Differences in CXCR4-mediated signaling in B cells

Immunobiology - Tập 211 - Trang 377-389 - 2006
Elena Palmesino1, Barbara Moepps2, Peter Gierschik2, Marcus Thelen1
1Institute for Research in Biomedicine, Via Vincenzo Vela 6, CH-6500 Bellinzona, Switzerland
2Department of Pharmacology and Toxicology, University of Ulm, D-89081 Ulm, Germany

Tài liệu tham khảo

Allen, 2004, Germinal center dark and light zone organization is mediated by CXCR4 and CXCR5, Nat. Immunol., 5, 943, 10.1038/ni1100 Amara, 1997, HIV coreceptor downregulation as antiviral principle: SDF-1α-dependent internalization of the chemokine receptor CXCR4 contributes to inhibition of HIV replication, J. Exp. Med., 186, 139, 10.1084/jem.186.1.139 Ansel, 2000, A chemokine-driven positive feedback loop organizes lymphoid follicles, Nature, 406, 309, 10.1038/35018581 Azzi, 2003, Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors, Proc. Natl. Acad. Sci. USA, 100, 11406, 10.1073/pnas.1936664100 Baggiolini, 1998, Chemokines and leukocyte traffic, Nature, 392, 565, 10.1038/33340 Baggiolini, 1987, Inhibition of the phagocytosis-induced respiratory burst by the fungal metabolite wortmannin and some analogues, Exp. Cell Res., 169, 408, 10.1016/0014-4827(87)90201-1 Balabanian, 2005, WHIM syndromes with different genetic anomalies are accounted for by impaired CXCR4 desensitization to CXCL12, Blood, 105, 2449, 10.1182/blood-2004-06-2289 Baribaud, 2001, Antigenically distinct conformations of CXCR4, J. Virol., 75, 8957, 10.1128/JVI.75.19.8957-8967.2001 Benard, 1999, Characterization of rac and cdc42 activation in chemoattractant-stimulated human neutrophils using a novel assay for active GTPases, J. Biol. Chem., 274, 13198, 10.1074/jbc.274.19.13198 Brandes, 2000, Activation-dependent modulation of B lymphocyte migration to chemokines, Int. Immunol., 12, 1285, 10.1093/intimm/12.9.1285 Cherla, 2001, Stromal cell-derived factor 1 alpha-induced chemotaxis in T cells is mediated by nitric oxide signaling pathways, J. Immunol., 166, 3067, 10.4049/jimmunol.166.5.3067 D’Apuzzo, 1997, The chemokine SDF-1, stromal cell-derived factor 1, attracts early stage B cell precursors via the chemokine receptor CXCR4, Eur. J. Immunol., 27, 1788, 10.1002/eji.1830270729 Egawa, 2001, The earliest stages of B cell development require a chemokine stromal cell-derived factor/pre-b cell growth-stimulating factor, Immunity, 15, 323, 10.1016/S1074-7613(01)00185-6 Erickson, 2003, A genetic lesion that arrests plasma cell homing to the bone marrow, Proc. Natl. Acad. Sci. USA, 100, 12905, 10.1073/pnas.2131686100 Etienne-Manneville, 2002, Rho GTPases in cell biology, Nature, 420, 629, 10.1038/nature01148 Fedyk, 1999, Maturation decreases responsiveness of human bone marrow B lineage cells to stromal-derived factor 1 (SDF-1), J. Leukoc. Biol., 66, 667, 10.1002/jlb.66.4.667 Fenteany, 2004, Cytoskeletal remodeling in leukocyte function, Curr. Opin. Hematol., 11, 15, 10.1097/00062752-200401000-00004 Forster, 1998, Intracellular and surface expression of the HIV-1 coreceptor CXCR4/fusin on various leukocyte subsets: Rapid internalization and recycling upon activation, J. Immunol., 160, 1522, 10.4049/jimmunol.160.3.1522 Forster, 1996, A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen, Cell, 87, 1037, 10.1016/S0092-8674(00)81798-5 Forster, 1999, CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs, Cell, 99, 23, 10.1016/S0092-8674(00)80059-8 Giannini, 1995, Phosphorylation, dephosphorylation, and recycling of the C5a receptor in differentiated HL60 cells, J. Immunol., 154, 4055, 10.4049/jimmunol.154.8.4055 Glodek, 2003, Sustained activation of cell adhesion is a differentially regulated process in B lymphopoiesis, J. Exp. Med., 197, 461, 10.1084/jem.20021477 Glogauer, 2000, Two pathways through Cdc42 couple the N-formyl receptor to actin nucleation in permeabilized human neutrophils, J. Cell Biol., 150, 785, 10.1083/jcb.150.4.785 Gulino, 2004, Altered leukocyte response to CXCL12 in patients with Warts Hypogammaglobulinemia, Infections, Myelokathexis (WHIM) syndrome, Blood, 104, 444, 10.1182/blood-2003-10-3532 Hargreaves, 2001, A coordinated change in chemokine responsiveness guides plasma cell movements, J. Exp. Med., 194, 45, 10.1084/jem.194.1.45 Hernandez, 2003, Mutations in the chemokine receptor gene CXCR4 are associated with WHIM syndrome, a combined immunodeficiency disease, Nat. Genet., 34, 70, 10.1038/ng1149 Honczarenko, 1999, SDF-1 responsiveness does not correlate with CXCR4 expression levels of developing human bone marrow B cells, Blood, 94, 2990, 10.1182/blood.V94.9.2990 Illenberger, 1998, Stimulation of phospholipase C-β2 by the rho GTPases Cdc42Hs and Rac1, EMBO J., 17, 6241, 10.1093/emboj/17.21.6241 Illenberger, 2003, Specificity and structural requirements of phospholipase C-beta stimulation by Rho GTPases versus G protein beta gamma dimers, J. Biol. Chem., 278, 3006, 10.1074/jbc.M208282200 Kenakin, 2001, Inverse, protean, and ligand-selective agonism: matters of receptor conformation, FASEB J., 15, 598, 10.1096/fj.00-0438rev Kim, 1999, Chemokines: signal lamps for trafficking of T and B cells for development and effector function, J. Leukoc. Biol., 65, 6, 10.1002/jlb.65.1.6 Knall, 1997, Interleukin 8-stimulated phosphatidylinositol-3-kinase activity regulates the migration of human neutrophils independent of extracellular signal-regulated kinase and p38 mitogen-activated protein kinases, Proc. Natl. Acad. Sci. USA, 94, 3052, 10.1073/pnas.94.7.3052 Korsmeyer, 1983, Immunoglobulin gene rearrangement and cell surface antigen expression in acute lymphocytic leukemias of T cell and B cell precursor origins, J. Clin. Invest., 71, 301, 10.1172/JCI110770 Kunkel, 2003, Plasma-cell homing, Nat. Rev. Immunol., 3, 822, 10.1038/nri1203 Lapidot, 2002, Current understanding of stem cell mobilization: the roles of chemokines, proteolytic enzymes, adhesion molecules, cytokines, and stromal cells, Exp. Hematol., 30, 973, 10.1016/S0301-472X(02)00883-4 Liles, 2003, Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist, Blood, 102, 2728, 10.1182/blood-2003-02-0663 Liu, 1996, Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply exposed individuals to HIV-1 infection, Cell, 86, 367, 10.1016/S0092-8674(00)80110-5 Loetscher, 1994, Monocyte chemotactic proteins MCP-1, MCP-2, and MCP-3 are major attractants for human CD4+ and CD8+ T lymphocytes, FASEB J., 8, 1055, 10.1096/fasebj.8.13.7926371 Luttrell, 1999, Regulation of tyrosine kinase cascades by G-protein-coupled receptors, Curr. Opin. Cell Biol., 11, 177, 10.1016/S0955-0674(99)80023-4 Luttrell, 1999, β-arrestin-dependent formation of β2 adrenergic receptor Src protein kinase complexes, Science, 283, 655, 10.1126/science.283.5402.655 Ma, 1999, The chemokine receptor CXCR4 is required for the retention of B lineage and granulocytic precursors within the bone marrow microenvironment, Immunity, 10, 463, 10.1016/S1074-7613(00)80046-1 Martin, 2003, Chemokines acting via CXCR2 and CXCR4 control the release of neutrophils from the bone marrow and their return following senescence, Immunity, 19, 583, 10.1016/S1074-7613(03)00263-2 Mecsas, 2004, Evolutionary genetics: CCR5 mutation and plague protection, Nature, 427, 606, 10.1038/427606a Moepps, 2000, Characterization of a Xenopus laevis CXC chemokine receptor 4: implications for hematopoietic cell development in the vertebrate embryo, Eur. J. Immunol., 30, 2924, 10.1002/1521-4141(200010)30:10<2924::AID-IMMU2924>3.0.CO;2-Y Moser, 2004, Chemokines: multiple levels of leukocyte migration control, Trends Immunol., 25, 75, 10.1016/j.it.2003.12.005 Murphy, 2000, International union of pharmacology, XXII: nomenclature for chemokine receptors, Pharmacol. Rev., 52, 145 Nagasawa, 1996, Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1, Nature, 382, 635, 10.1038/382635a0 Neptune, 1997, Receptors induce chemotaxis by releasing the β gamma subunit of Gi, not by activating Gq or Gs, Proc. Natl. Acad. Sci. USA, 94, 14489, 10.1073/pnas.94.26.14489 Neptune, 1999, Gαi is not required for chemotaxis mediated by Gi-coupled receptors, J. Biol. Chem., 274, 2824, 10.1074/jbc.274.5.2824 Odendahl, 2005, Generation of migratory antigen-specific plasma blasts and mobilization of resident plasma cells in a secondary immune response, Blood, 105, 1614, 10.1182/blood-2004-07-2507 Ogilvie, 2001, Eotaxin is a natural antagonist for CCR2 and an agonist for CCR5, Blood, 97, 1920, 10.1182/blood.V97.7.1920 Ogilvie, 2004, Unusual chemokine receptor antagonism involving a mitogen-activated protein kinase pathway, J. Immunol., 172, 6715, 10.4049/jimmunol.172.11.6715 Patrucco, 2004, PI3Kgamma modulates the cardiac response to chronic pressure overload by distinct kinase-dependent and -independent effects, Cell, 118, 375, 10.1016/j.cell.2004.07.017 Pierce, 2002, Signalling: Seven-transmembrane receptors, Nat. Rev. Mol. Cell Biol., 3, 639, 10.1038/nrm908 Rabiet, 2002, Inhibitory effects of a dominant-interfering form of the Rho-GTPase Cdc42 in the chemoattractant-elicited signaling pathways leading to NADPH oxidase activation in differentiated HL-60 cells, Blood, 100, 1835, 10.1182/blood-2001-12-0193 Ridley, 1992, Distinct patterns of actin organization regulated by the small GTP-binding proteins Rac and Rho, Cold Spring Harbor Symp. Quant. Biol., 57, 661, 10.1101/SQB.1992.057.01.072 Samson, 1996, Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene, Nature, 382, 722, 10.1038/382722a0 Sander, 1998, Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell–cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase, J. Cell Biol., 143, 1385, 10.1083/jcb.143.5.1385 Smit, M.J., Verdijk, P., Van Der Raaij-Helmer, E.M., Navis, M., Hensbergen, P.J., Leurs, R., Tensen, C.P., 2003. CXCR3-mediated chemotaxis of human T cells is regulated by a Gi- and phospholipase C-dependent pathway and not via activation of MEK/p44/p42 MAPK nor Akt/PI-3-kinase. Blood. Snyder, 2003, The pleckstrin homology domain of phospholipase C-beta 2 as an effector site for Rac, J. Biol. Chem., 278, 21099, 10.1074/jbc.M301418200 Sotsios, 1999, The CXC chemokine stromal cell-derived factor activates a Gi-coupled phosphoinositide 3-kinase in T lymphocytes, J. Immunol., 163, 5954, 10.4049/jimmunol.163.11.5954 Srinivasan, 2003, Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P3 and polarity during neutrophil chemotaxis, J. Cell Biol., 160, 375, 10.1083/jcb.200208179 Tachibana, 1998, The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract, Nature, 393, 591, 10.1038/31261 Thelen, 2001, Dancing to the tune of chemokines, Nat. Immunol., 2, 129, 10.1038/84224 Thelen, 1994, Wortmannin binds specifically to 1-phosphatidylinositol 3-kinase while inhibiting guanine nucleotide-binding protein-coupled receptor signaling in neutrophil leukocytes, Proc. Natl. Acad. Sci. USA, 91, 4960, 10.1073/pnas.91.11.4960 Thompson, 1998, Delineation of the Cdc42/Rac-binding domain of p21-activated kinase, Biochemistry, 37, 7885, 10.1021/bi980140+ Tilton, 2000, Signal transduction by CXC chemokine receptor 4: stromal cell-derived factor 1 stimulates prolonged protein kinase b and extracellular signal-regulated kinase 2 activation in t lymphocytes, J. Exp. Med., 192, 313, 10.1084/jem.192.3.313 Van Buul, 2003, Leukocyte-endothelium interaction promotes SDF-1-dependent polarization of CXCR4, J. Biol. Chem., 278, 30302, 10.1074/jbc.M304764200 Wain, 2002, Leucocyte chemotaxis: Examination of mitogen-activated protein kinase and phosphoinositide 3-kinase activation by Monocyte Chemoattractant Proteins-1, -2, -3 and -4, Clin. Exp. Immunol., 127, 436, 10.1046/j.1365-2249.2002.01764.x Wang, 2002, PAK1 kinase is required for CXCL1-induced chemotaxis, Biochemistry, 41, 7100, 10.1021/bi025902m Xythalis, 2002, Inhibition of IL-8-mediated MAPK activation in human neutrophils by beta1 integrin ligands, Inflammation, 26, 83, 10.1023/A:1014836211643 Yen, 1997, MCP-1-mediated chemotaxis requires activation of non-overlapping signal transduction pathways, J. Leukoc. Biol., 61, 529, 10.1002/jlb.61.4.529 Zou, 1998, Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development, Nature, 393, 595, 10.1038/31269