Dietary citrulline does not modify rat colon tumor response to chemotherapy, but failed to improve nutritional status

Clinical Nutrition - Tập 40 - Trang 4560-4568 - 2021
C. Breuillard1,2,3, C. Moinard2,3, A. Goron3, N. Neveux2,4, A. De Reviers3, V.C. Mazurak5, L. Cynober2,4, V.E. Baracos1
1Department of Oncology, University of Alberta, Edmonton, Canada
2Nutrition Laboratory EA 4466, Paris Descartes University, Paris, France
3Univ. Grenoble Alpes, Inserm U1055, LBFA, Grenoble, France
4Clinical Chemistry, Cochin Hospital, APHP, Paris, France
5Division of Human Nutrition, Department of Agricultural Food & Nutritional Science, University of Alberta, Edmonton, Canada

Tài liệu tham khảo

Fearon, 2011, Definition and classification of cancer cachexia: an international consensus, Lancet Oncol, 12, 489, 10.1016/S1470-2045(10)70218-7 Fearon, 2013, Understanding the mechanisms and treatment options in cancer cachexia, Nat Rev Clin Oncol, 10, 90, 10.1038/nrclinonc.2012.209 Martin, 2015, Diagnostic criteria for the classification of cancer-associated weight loss, J Clin Oncol, 33, 90, 10.1200/JCO.2014.56.1894 Prado, 2011, Two faces of drug therapy in cancer: drug-related lean tissue loss and its adverse consequences to survival and toxicity, Curr Opin Clin Nutr Metab Care, 14, 250, 10.1097/MCO.0b013e3283455d45 Arends, 2017, ESPEN expert group recommendations for action against cancer-related malnutrition, Clin Nutr, 36, 1187, 10.1016/j.clnu.2017.06.017 Arends, 2017, ESPEN guidelines on nutrition in cancer patients, Clin Nutr, 36, 11, 10.1016/j.clnu.2016.07.015 Chevalier, 2014, Do patients with advanced cancer have any potential for protein anabolism in response to amino acid therapy?, Curr Opin Clin Nutr Metab Care, 17, 213, 10.1097/MCO.0000000000000047 Breuillard, 2018, Citrulline and skeletal muscle, 309 Moinard, 2015, Citrulline supplementation induces changes in body composition and limits age-related metabolic changes in healthy male rats, J Nutr, 145, 1429 Bouillanne, 2019, Impact of 3-week citrulline supplementation on postprandial protein metabolism in malnourished older patients: the Ciproage randomized controlled trial, Clin Nutr, 38, 564, 10.1016/j.clnu.2018.02.017 Le Plénier, 2017, Citrulline directly modulates muscle protein synthesis via the PI3K/MAPK/4E-BP1 pathway in a malnourished state: evidence from in vivo, ex vivo, and in vitro studies, Am J Physiol Endocrinol Metab, 312, E27, 10.1152/ajpendo.00203.2016 Ventura, 2013, Effect of citrulline on muscle functions during moderate dietary restriction in healthy adult rats, Amino Acids, 45, 1123, 10.1007/s00726-013-1564-3 Osowska, 2006, Citrulline modulates muscle protein metabolism in old malnourished rats, Am J Physiol Endocrinol Metab, 291, E582, 10.1152/ajpendo.00398.2005 Crenn, 2008, Citrulline as a biomarker of intestinal failure due to enterocyte mass reduction, Clin Nutr, 27, 328, 10.1016/j.clnu.2008.02.005 Engelen, 2018, Major surgery diminishes systemic arginine availability and suppresses nitric oxide response to feeding in patients with early stage breast cancer, Clin Nutr, 37, 1645, 10.1016/j.clnu.2017.07.019 Goron, 2017, Synergistic effects of citrulline supplementation and exercise on performance in male rats: evidence for implication of protein and energy metabolisms, Clin Sci, 131, 775, 10.1042/CS20170088 Lim, 2015, Current clinical regulation of PI3K/PTEN/Akt/mTOR signaling in treatment of human cancer, J Canc Res Clin Oncol, 141, 671, 10.1007/s00432-014-1803-3 Akashi, 2001, Citrulline, a novel compatible solute in drought-tolerant wild watermelon leaves, is an efficient hydroxyl radical scavenger, FEBS Lett, 508, 438, 10.1016/S0014-5793(01)03123-4 Fu, 2014, Antioxidants decrease the apoptotic effect of 5-Fu in colon cancer by regulating Src-dependent caspase-7 phosphorylation, Cell Death Dis, 5, e983, 10.1038/cddis.2013.509 Gajek, 2020, Antagonistic effects of CAPE (a Component of Propolis) on the cytotoxicity and genotoxicity of Irinotecan and SN38 in Human gastrointestinal cancer cells in vitro, Molecules, 25, 658, 10.3390/molecules25030658 Giles, 2016, Diet composition as a source of variation in experimental animal models of cancer cachexia, J Cachexia Sarcopenia Muscle, 7, 110, 10.1002/jcsm.12058 Almasud, 2017, Fish oil mitigates myosteatosis and improves chemotherapy efficacy in a preclinical model of colon cancer, PloS One, 12, 10.1371/journal.pone.0183576 Xue, 2009, Br J Nutr, 102, 434, 10.1017/S0007114508199482 Lin, 2014, The role of intestinal microbiota in development of irinotecan toxicity and in toxicity reduction through dietary fibres in rats, PloS One, 9 Cao, 2000, Synergistic antitumor activity of irinotecan in combination with 5-fluorouracil in rats bearing advanced colorectal cancer: role of drug sequence and dose, Canc Res, 60, 3717 Blandizzi, 2001, Characterization of a novel mechanism accounting for the adverse cholinergic effects of the anticancer drug irinotecan, Br J Pharmacol, 132, 73, 10.1038/sj.bjp.0703766 Neveux, 2004, Measurement of amino acid concentrations in biological fluids and tissues using ion exchange chromatography, 17e28 Le Guen, 2016, A 9-wk docosahexaenoic acid-enriched supplementation improves endurance exercise capacity and skeletal muscle mitochondrial function in adult rats, Am J Physiol Endocrinol Metab, 310, E213, 10.1152/ajpendo.00468.2014 Ham, 2014, Glycine administration attenuates skeletal muscle wasting in a mouse model of cancer cachexia, Clin Nutr, 33, 448, 10.1016/j.clnu.2013.06.013 Grossie, 1996, Citrulline and arginine increase the growth of the ward colon tumor in parenterally fed rats, Nutr Canc, 26, 91, 10.1080/01635589609514466 Goron, 2019, Citrulline stimulates muscle protein synthesis, by reallocating ATP consumption to muscle protein synthesis, J Cachexia Sarcopenia Muscle, 10, 919, 10.1002/jcsm.12435 Xu, 2002, Irinotecan: mechanisms of tumor resistance and novel strategies for modulating its activity, Ann Oncol, 13, 1841, 10.1093/annonc/mdf337 Longley, 2003, 5-fluorouracil: mechanisms of action and clinical strategies, Nat Rev Canc, 3, 330, 10.1038/nrc1074 Jung, 2019, Antioxidant supplementation and breast cancer prognosis in postmenopausal women undergoing chemotherapy and radiation therapy, Am J Clin Nutr, 109, 69, 10.1093/ajcn/nqy223 Allerton, 2018, l-Citrulline supplementation: impact on cardiometabolic Health, Nutrients, 10, 921, 10.3390/nu10070921 Breuillard, 2015, In vitro anti-inflammatory effects of citrulline on peritoneal macrophages in Zucker diabetic fatty rats, Br J Nutr, 113, 120, 10.1017/S0007114514002086 Breuillard, 2017, Nitric oxide production by peritoneal macrophages from aged rats: a short term and direct modulation by citrulline, Biochimie, 133, 66, 10.1016/j.biochi.2016.10.020 Antunes, 2016, Pretreatment with L-citrulline positively affects the mucosal architecture and permeability of the small intestine in a murine mucositis model, J Parenter Enter Nutr, 40, 279, 10.1177/0148607114567508 Balage, 2001, Amino acids and insulin are both required to regulate assembly of the eIF4E. eIF4G complex in rat skeletal muscle, Am J Physiol Endocrinol Metab, 281, E565, 10.1152/ajpendo.2001.281.3.E565