Dietary ascorbic acid and muscle carnitine (β-OH-γ-(trimethylamino) butyric acid) in guinea-pigs

British Journal of Nutrition - Tập 43 Số 2 - Trang 385-387 - 1980
R. E. Hughes1, Robert Hurley1, Eleri Jones1
1University of Wales Institute of Science and Technology, Cardiff, Wales

Tóm tắt

Tissue ascorbic acid (AA) contents of approximately 12 and 100% saturation respectively were produced in two groups of guinea-pigs. The ‘low-AA’ group had significantly lower muscle carnitine concentrations than the ‘high-AA’group. There was no concomitant emergence of the symptoms customarily regarded as characteristic of hypovitaminosis C. It is concluded that muscle carnitine (β-OH-γ-(trimethylamino) butyric acid) is a highly-sensitive indicator of tissue AA contents; this could account for the lassitude and fatigue reported to precede the emergence of frank scurvy in man.

Từ khóa


Tài liệu tham khảo

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Thông tin
Thông tin xuất bản

British Journal of Nutrition

Tập 43 Số 2

385-387

Thông tin tác giả