Dietary Cholesterol Oxidation Products Accelerate Plaque Destabilization and Rupture Associated with Monocyte Infiltration/Activation via the MCP-1-CCR2 Pathway in Mouse Brachiocephalic Arteries: Therapeutic Effects of Ezetimibe

1) Steinberg D. Lewis A: Conner memorial lecture. Oxidative modification of ldl and atherogenesis. Circulation, 1997; 95: 1062-1071

2) Libby P, Ridker PM, Maseri A: Inflammation and atherosclerosis. Circulation, 2002; 105: 1135-1143

3) Libby P, Aikawa M: Stabilization of atherosclerotic plaques: New mechanisms and clinical targets. Nat Med, 2002; 8: 1257-1262

10.1016/S0021-9150(98)00196-8

5) Carpenter KL: Good cop, bad cop: An unsolved murder. Are dietary cholesterol oxidation products guilty of atherogenicity ? Br J Nutr, 2002; 88: 335-338

10.1194/jlr.M200266-JLR200

10.1080/10715760100300571

10.1161/01.ATV.20.3.708

9) Staprans I, Pan XM, Rapp JH, Feingold KR: Oxidized cholesterol in the diet accelerates the development of aortic atherosclerosis in cholesterol-fed rabbits. Arterioscler Thromb Vasc Biol, 1998; 18: 977-983

10) Falk E, Shah PK, Fuster V: Coronary plaque disruption. Circulation, 1995; 92: 657-671

10.5551/jat.3939

10.1126/science.1093131

10.1194/jlr.M600261-JLR200

10.1161/hq1201.100260

10.1016/j.atherosclerosis.2008.05.026

10.1161/01.ATV.20.12.2587

10.1161/01.CIR.0000158435.98035.8D

10.1172/JCI25074

19) Clarke MC, Figg N, Maguire JJ, Davenport AP, Goddard M, Littlewood TD, Bennett MR: Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis. Nat Med, 2006; 12: 1075-1080

10.5551/jat.8136

10.5551/jat.7211

10.1161/01.ATV.0000143384.69170.2d

23) Osada K, Kodama T, Minehira K, Yamada K, Sugano M: Dietary protein modifies oxidized cholesterol-induced alterations of linoleic acid and cholesterol metabolism in rats. J Nutr, 1996; 126: 1635-1643

10.1161/01.ATV.0000118275.60121.2b

10.1016/j.atherosclerosis.2008.02.001

26) Satoh K, Nigro P, Matoba T, O' Dell MR, Cui Z, Shi X, Mohan A, Yan C, Abe J, Illig KA, Berk BC: Cyclophilin a enhances vascular oxidative stress and the development of angiotensin ii-induced aortic aneurysms. Nat Med, 2009; 15: 649-656

27) Usui S, Hara Y, Hosaki S, Okazaki M: A new on-line dual enzymatic method for simultaneous quantification of cholesterol and triglycerides in lipoproteins by hplc. J Lipid Res, 2002; 43: 805-814

10.1161/CIRCULATIONAHA.107.745174

28) Ishigaki Y, Katagiri H, Gao J, Yamada T, Imai J, Uno K, Hasegawa Y, Kaneko K, Ogihara T, Ishihara H, Sato Y, Takikawa K, Nishimichi N, Matsuda H, Sawamura T, Oka Y: Impact of plasma oxidized low-density lipoprotein removal on atherosclerosis. Circulation, 2008; 118: 75-83

10.1016/S0076-6879(84)05042-4

30) Swirski FK, Libby P, Aikawa E, Alcaide P, Luscinskas FW, Weissleder R, Pittet MJ: Ly-6chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata. J Clin Invest, 2007; 117: 195-205

10.1172/JCI29950

10.1172/JCI28549

32) Crisby M, Nordin-Fredriksson G, Shah PK, Yano J, Zhu J, Nilsson J: Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: Implications for plaque stabilization. Circulation, 2001; 103: 926-933

10.1016/S0735-1097(98)00250-2

10.1067/mhj.2001.112238