Dichotomous Role of Plasmin in Regulation of Macrophage Function after Acetaminophen Overdose

The American Journal of Pathology - Tập 189 - Trang 1986-2001 - 2019
Katherine Roth1,2,3, Jenna Strickland1,2, Nikita Joshi2,4, Meihong Deng5, Rebekah C. Kennedy1,2, Cheryl E. Rockwell1,2,3, James P. Luyendyk2,4, Timothy R. Billiar5, Bryan L. Copple1,2,3
1Department of Pharmacology and Toxicology, Michigan State University, East Lansing, Michigan
2Institute for Integrative Toxicology, Michigan State University, East Lansing, Michigan
3Cell and Molecular Biology Program, Michigan State University, East Lansing, Michigan
4Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, Michigan
5Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania

Tài liệu tham khảo

Nourjah, 2006, Estimates of acetaminophen (Paracetomal)-associated overdoses in the United States, Pharmacoepidemiol Drug Saf, 15, 398, 10.1002/pds.1191 Lee, 2008, Acute liver failure: summary of a workshop, Hepatology, 47, 1401, 10.1002/hep.22177 Rumack, 1981, Acetaminophen overdose. 662 cases with evaluation of oral acetylcysteine treatment, Arch Intern Med, 141, 380, 10.1001/archinte.1981.00340030112020 Smilkstein, 1988, Efficacy of oral N-acetylcysteine in the treatment of acetaminophen overdose: analysis of the national multicenter study (1976 to 1985), N Engl J Med, 319, 1557, 10.1056/NEJM198812153192401 Fisher, 2013, Role of Kupffer cells and toll-like receptor 4 in acetaminophen-induced acute liver failure, J Surg Res, 180, 147, 10.1016/j.jss.2012.11.051 Holt, 2008, Identification and characterization of infiltrating macrophages in acetaminophen-induced liver injury, J Leukoc Biol, 84, 1410, 10.1189/jlb.0308173 Dambach, 2002, Role of CCR2 in macrophage migration into the liver during acetaminophen-induced hepatotoxicity in the mouse, Hepatology, 35, 1093, 10.1053/jhep.2002.33162 Zigmond, 2014, Infiltrating monocyte-derived macrophages and resident Kupffer cells display different ontogeny and functions in acute liver injury, J Immunol, 193, 344, 10.4049/jimmunol.1400574 Berry, 2010, Admission levels and early changes in serum interleukin-10 are predictive of poor outcome in acute liver failure and decompensated cirrhosis, Liver Int, 30, 733, 10.1111/j.1478-3231.2010.02219.x Antoniades, 2008, The importance of immune dysfunction in determining outcome in acute liver failure, J Hepatol, 49, 845, 10.1016/j.jhep.2008.08.009 Bhushan, 2014, Pro-regenerative signaling after acetaminophen-induced acute liver injury in mice identified using a novel incremental dose model, Am J Pathol, 184, 3013, 10.1016/j.ajpath.2014.07.019 Ploplis, 1998, Plasminogen deficiency differentially affects recruitment of inflammatory cell populations in mice, Blood, 91, 2005, 10.1182/blood.V91.6.2005 Wygrecka, 2009, Enolase-1 promotes plasminogen-mediated recruitment of monocytes to the acutely inflamed lung, Blood, 113, 5588, 10.1182/blood-2008-08-170837 Das, 2014, Plasminogen promotes macrophage phagocytosis in mice, Blood, 124, 679, 10.1182/blood-2014-01-549659 Borg, 2015, Dendritic cell-mediated phagocytosis but not immune activation is enhanced by plasmin, PLoS One, 10, e0131216, 10.1371/journal.pone.0131216 Sugimoto, 2017, Plasmin and plasminogen induce macrophage reprogramming and regulate key steps of inflammation resolution via annexin A1, Blood, 129, 2896, 10.1182/blood-2016-09-742825 Bezerra, 1999, Plasminogen deficiency leads to impaired remodeling after a toxic injury to the liver, Proc Natl Acad Sci U S A, 96, 15143, 10.1073/pnas.96.26.15143 Kawao, 2010, Role of plasminogen in macrophage accumulation during liver repair, Thromb Res, 125, e214, 10.1016/j.thromres.2009.12.009 Ling, 2004, Annexin II regulates fibrin homeostasis and neoangiogenesis in vivo, J Clin Invest, 113, 38, 10.1172/JCI19684 Griffin, 2001, A role for thrombin receptor signaling in endothelial cells during embryonic development, Science, 293, 1666, 10.1126/science.1061259 Deng, 2018, The endotoxin delivery protein HMGB1 mediates caspase-11-dependent lethality in sepsis, Immunity, 49, 740, 10.1016/j.immuni.2018.08.016 Mochizuki, 2014, Hepatic stellate cells orchestrate clearance of necrotic cells in a hypoxia-inducible factor-1alpha-dependent manner by modulating macrophage phenotype in mice, J Immunol, 192, 3847, 10.4049/jimmunol.1303195 Kim, 2006, Early growth response factor-1 is critical for cholestatic liver injury, Toxicol Sci, 90, 586, 10.1093/toxsci/kfj111 Schwarz, 2014, Residual endotoxin contaminations in recombinant proteins are sufficient to activate human CD1c+ dendritic cells, PLoS One, 9, e113840, 10.1371/journal.pone.0113840 Carmo, 2014, Plasmin induces in vivo monocyte recruitment through protease-activated receptor-1-, MEK/ERK-, and CCR2-mediated signaling, J Immunol, 193, 3654, 10.4049/jimmunol.1400334 Laumonnier, 2006, Identification of the annexin A2 heterotetramer as a receptor for the plasmin-induced signaling in human peripheral monocytes, Blood, 107, 3342, 10.1182/blood-2005-07-2840 Huebener, 2015, The HMGB1/RAGE axis triggers neutrophil-mediated injury amplification following necrosis, J Clin Invest, 125, 539, 10.1172/JCI76887 Antoine, 2009, High-mobility group box-1 protein and keratin-18, circulating serum proteins informative of acetaminophen-induced necrosis and apoptosis in vivo, Toxicol Sci, 112, 521, 10.1093/toxsci/kfp235 Cresci, 2015, Alternative complement pathway component factor D contributes to efficient clearance of tissue debris following acute CCl(4)-induced injury, Mol Immunol, 64, 9, 10.1016/j.molimm.2014.10.017 Arnold, 2007, Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis, J Exp Med, 204, 1057, 10.1084/jem.20070075 Odaka, 2003, Murine macrophages produce secretory leukocyte protease inhibitor during clearance of apoptotic cells: implications for resolution of the inflammatory response, J Immunol, 171, 1507, 10.4049/jimmunol.171.3.1507 Fadok, 1998, Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF, J Clin Invest, 101, 890, 10.1172/JCI1112 Yang, 2014, Monocyte and macrophage differentiation: circulation inflammatory monocyte as biomarker for inflammatory diseases, Biomark Res, 2, 1, 10.1186/2050-7771-2-1 Gao, 2018, Excessive plasmin compromises hepatic sinusoidal vascular integrity after acetaminophen overdose, Hepatology, 68, 1991, 10.1002/hep.30070 Gong, 2008, Inflammatory macrophage migration requires MMP-9 activation by plasminogen in mice, J Clin Invest, 118, 3012, 10.1172/JCI32750 Swaisgood, 2007, Plasminogen is an important regulator in the pathogenesis of a murine model of asthma, Am J Respir Crit Care Med, 176, 333, 10.1164/rccm.200609-1345OC Hultman, 2014, Plasmin deficiency leads to fibrin accumulation and a compromised inflammatory response in the mouse brain, J Thromb Haemost, 12, 701, 10.1111/jth.12553 Syrovets, 2001, Plasmin-induced expression of cytokines and tissue factor in human monocytes involves AP-1 and IKKbeta-mediated NF-kappaB activation, Blood, 97, 3941, 10.1182/blood.V97.12.3941 Weide, 1996, Plasmin is a specific stimulus of the 5-lipoxygenase pathway of human peripheral monocytes, Thromb Haemost, 76, 561, 10.1055/s-0038-1650623 Miles, 1991, Role of cell-surface lysines in plasminogen binding to cells: identification of alpha-enolase as a candidate plasminogen receptor, Biochemistry, 30, 1682, 10.1021/bi00220a034 Miles, 2017, Deficiency of plasminogen receptor, Plg-RKT, causes defects in plasminogen binding and inflammatory macrophage recruitment in vivo, J Thromb Haemost, 15, 155, 10.1111/jth.13532 Lighvani, 2011, Regulation of macrophage migration by a novel plasminogen receptor Plg-R KT, Blood, 118, 5622, 10.1182/blood-2011-03-344242 Abraham, 2000, HMG-1 as a mediator of acute lung inflammation, J Immunol, 165, 2950, 10.4049/jimmunol.165.6.2950 Andersson, 2000, High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes, J Exp Med, 192, 565, 10.1084/jem.192.4.565 Yang, 2013, The many faces of HMGB1: molecular structure-functional activity in inflammation, apoptosis, and chemotaxis, J Leukoc Biol, 93, 865, 10.1189/jlb.1212662 Ge, 2014, High mobility group box-1 (HMGB1) participates in the pathogenesis of alcoholic liver disease (ALD), J Biol Chem, 289, 22672, 10.1074/jbc.M114.552141 Youn, 2008, High mobility group box 1 protein binding to lipopolysaccharide facilitates transfer of lipopolysaccharide to CD14 and enhances lipopolysaccharide-mediated TNF-alpha production in human monocytes, J Immunol, 180, 5067, 10.4049/jimmunol.180.7.5067 Qin, 2009, HMGB1 enhances the proinflammatory activity of lipopolysaccharide by promoting the phosphorylation of MAPK p38 through receptor for advanced glycation end products, J Immunol, 183, 6244, 10.4049/jimmunol.0900390 Tian, 2007, Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE, Nat Immunol, 8, 487, 10.1038/ni1457 Schiraldi, 2012, HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4, J Exp Med, 209, 551, 10.1084/jem.20111739 Parkkinen, 1991, Interactions of plasminogen and tissue plasminogen activator (t-PA) with amphoterin: enhancement of t-PA-catalyzed plasminogen activation by amphoterin, J Biol Chem, 266, 16730, 10.1016/S0021-9258(18)55362-X Ito, 2008, Proteolytic cleavage of high mobility group box 1 protein by thrombin-thrombomodulin complexes, Arterioscler Thromb Vasc Biol, 28, 1825, 10.1161/ATVBAHA.107.150631 Roy, 2014, Mast cell chymase degrades the alarmins heat shock protein 70, biglycan, HMGB1, and interleukin-33 (IL-33) and limits danger-induced inflammation, J Biol Chem, 289, 237, 10.1074/jbc.M112.435156 Marchetti, 2012, High mobility group box 1 is a novel substrate of dipeptidyl peptidase-IV, Diabetologia, 55, 236, 10.1007/s00125-011-2213-6 Kopec, 2017, Fibrin(ogen) drives repair after acetaminophen-induced liver injury via leukocyte alphaMbeta2 integrin-dependent upregulation of Mmp12, J Hepatol, 66, 787, 10.1016/j.jhep.2016.12.004 Monea, 2002, Plasmin activates pro-matrix metalloproteinase-2 with a membrane-type 1 matrix metalloproteinase-dependent mechanism, J Cell Physiol, 192, 160, 10.1002/jcp.10126 Ito, 2005, Inhibition of matrix metalloproteinases minimizes hepatic microvascular injury in response to acetaminophen in mice, Toxicol Sci, 83, 190, 10.1093/toxsci/kfh291 Lisman, 2012, Intact thrombin generation and decreased fibrinolytic capacity in patients with acute liver injury or acute liver failure, J Thromb Haemost, 10, 1312, 10.1111/j.1538-7836.2012.04770.x