Diagnosi dell’ipoglicemia nell’adulto non diabetico

Springer Science and Business Media LLC - Tập 22 - Trang 298-304 - 2021
Damiano Gullo1, Miriam Magliozzo1, Antonino Belfiore1, Maria Luisa Arpi1
1U.O.C. di Endocrinologia, Dipartimento di Medicina Clinica e Sperimentale, Università di Catania, Ospedale Garibaldi-Nesima, Catania, Italia

Tóm tắt

Nei soggetti adulti non diabetici che presentano ipoglicemia (glucosio $<55~\text{mg/dL}$ ) è necessario documentare la presenza di 3 condizioni, triade di Whipple: bassi valori glicemici, segni e sintomi clinici compatibili con l’ipoglicemia e loro risoluzione dopo aumento della glicemia. L’ipoglicemia può essere secondaria a farmaci (anche a uso surrettizio), a neoplasie (insulinomi), a sindromi autoimmuni (acido alfa lipoico), a forme reattive (idiopatiche, chirurgia dell’apparato digerente, prediabete). L’intossicazione da alcool e le malattie gravi come l’insufficienza epatica, lo scompenso cardiaco e la sepsi possono anche essere associate a ipoglicemia. Per indirizzare il paziente nel corretto percorso di diagnosi, per le forme tumorali o autoimmuni sono stati definiti protocolli standardizzati, diversamente da quanto accade per le forme reattive o post-prandiali, per le quali non sono ancora disponibili percorsi diagnostici condivisi e, pertanto, l’esame clinico e anamnestico svolgono un ruolo essenziale.

Tài liệu tham khảo

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