Diabetes induces tri-methylation at lysine 9 of histone 3 at Slc2a4 gene in skeletal muscle: A new target to improve glycemic control

Alves-Wagner, 2014, Decreased diabetes-induced glycemic impairment in WKY and SHR involves enhanced skeletal muscle Slc2a4/GLUT4 expression, Diabetol. Metab. Syndrome, 6, 97, 10.1186/1758-5996-6-97 Bannister, 2011, Regulation of chromatin by histone modifications, Cell Res., 21, 381, 10.1038/cr.2011.22 Blättler, 2012, Yin Yang 1 deficiency in skeletal muscle protects against rapamycin-induced diabetic-like symptoms through activation of insulin/IGF signaling, Cell Metabol., 15, 505, 10.1016/j.cmet.2012.03.008 Cantó, 2009, AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity, Nature, 458, 1056, 10.1038/nature07813 Cooke, 1999, Transcription factor NF1 mediates repression of the GLUT4 promoter by cyclic-AMP, Biochem. Biophys. Res. Commun., 260, 600, 10.1006/bbrc.1999.0959 Corrêa-Giannella, 2013, SLC2A4 gene: a promising target for pharmacogenomics of insulin resistance, Pharmacogenomics, 14, 847, 10.2217/pgs.13.45 Djazayery, 1973, The use of gold-thioglucose and monosodium glutamate to induce obesity in mice, Proc. Nutr. Soc., 32, 30A Fontcuberta-PiSunyer, 2018, Modulation of the endocrine transcriptional program by targeting histone modifiers of the H3K27me3 mark, Biochim. Biophys. Acta, 1861, 473, 10.1016/j.bbagrm.2018.03.003 Furuya, 2010, Anti-inflammatory effect of atorvastatin ameliorates insulin resistance in monosodium glutamate-treated obese mice, Metabolism, 59, 395, 10.1016/j.metabol.2009.08.011 Gaster, 2001, GLUT4 is reduced in slow muscle fibers of type 2 diabetic patients: is insulin resistance in type 2 diabetes a slow, type 1 fiber disease?, Diabetes, 50, 1324, 10.2337/diabetes.50.6.1324 Gibney, 2010, Epigenetics and gene expression, Heredity (Edinb)., 105, 4, 10.1038/hdy.2010.54 Goh, 2014, Effects of resveratrol in patients with type 2 diabetes mellitus on skeletal muscle SIRT1 expression and energy expenditure, Int. J. Sport Nutr. Exerc. Metabol., 24, 2, 10.1123/ijsnem.2013-0045 Gray, 2002, The Krüppel-like factor KLF15 regulates the insulin-sensitive glucose transporter GLUT4, J. Biol. Chem., 277, 34322, 10.1074/jbc.M201304200 Gut, 2013, The nexus of chromatin regulation and intermediary metabolism, Nature, 502, 489, 10.1038/nature12752 Herman, 2006, Glucose transport and sensing in the maintenance of glucose homeostasis and metabolic harmony, J. Clin. Invest., 116, 1767, 10.1172/JCI29027 Howlett, 2016, Epigenetic regulation of skeletal muscle metabolism, Clin. Sci., 130, 1051, 10.1042/CS20160115 Im, 2007, Regulation of glucose transporter type 4 isoform gene expression in muscle and adipocytes, IUBMB Life, 59, 134, 10.1080/15216540701313788 Ito-Nagahata, 2013, Stilbene analogs of resveratrol improve insulin resistance through activation of AMPK, Biosci. Biotechnol. Biochem., 77, 1229, 10.1271/bbb.121000 Jaenisch, 2003, Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals, Nat. Genet., 33, 245, 10.1038/ng1089 Jeong, 2015, Insulin-response epigenetic activation of Egr-1 and JunB genes at the nuclear periphery by A-type lamin-associated pY19-Caveolin-2 in the inner nuclear membrane, Nucleic Acids Res., 43, 3114, 10.1093/nar/gkv181 Joost, 2002, Nomenclature of the GLUT/SLC2A family of sugar/polyol transport facilitators, Am. J. Physiol. Endocrinol. Metab., 282, E974, 10.1152/ajpendo.00407.2001 Khamzina, 2005, Increased activation of the mammalian target of rapamycin pathway in liver and skeletal muscle of obese rats: possible involvement in obesity-linked insulin resistance, Endocrinology, 146, 1473, 10.1210/en.2004-0921 Kirchner, 2013, Epigenetic flexibility in metabolic regulation: disease cause and prevention?, Trends Cell Biol., 23, 203, 10.1016/j.tcb.2012.11.008 Komeda, 1980, Diabetic syndrome in the Chinese hamster induced with monosodium glutamate, Experientia, 36, 232, 10.1007/BF01953751 Kouzarides, 2007, Chromatin modifications and their function, Cell, 128, 693, 10.1016/j.cell.2007.02.005 Kuo, 1999, In vivo cross-linking and immunoprecipitation for studying dynamic protein:DNA associations in a chromatin environment, Methods, 19, 425, 10.1006/meth.1999.0879 Leturque, 1996, Improvement of insulin action in diabetic transgenic mice selectively overexpressing GLUT4 in skeletal muscle, Diabetes, 45, 23, 10.2337/diab.45.1.23 Lima, 2009, Contractile activity per se induces transcriptional activation of SLC2A4 gene in soleus muscle: involvement of MEF2D, HIF-1a, and TRα transcriptional factors, Am. J. Physiol. Metab., 296, E132 Machado, 1993, Decreased glucose transporter (GLUT 4) content in insulin-sensitive tissues of obese aurothioglucose- and monosodium glutamate-treated mice, Horm. Metab. Res., 25, 462, 10.1055/s-2007-1002149 Moraes, 2014, Insulin acutely triggers transcription of Slc2a4 gene: participation of the AT-rich, E-box and NFKB-binding sites, Life Sci., 114, 36, 10.1016/j.lfs.2014.07.040 Moss, 1985, Cafeteria feeding promotes diet-induced thermogenesis in monosodium glutamate-treated mice, Metabolism, 34, 1094, 10.1016/0026-0495(85)90152-0 Mulligan, 2011, A SIRT1-LSD1 corepressor complex regulates Notch target gene expression and development, Mol. Cell, 42, 689, 10.1016/j.molcel.2011.04.020 Nemeroff, 1977, Analysis of the disruption in hypothalamic-pituitary regulation in rats treated neonatally with monosodium L-glutamate (MSG): evidence for the involvement of tuberoinfundibular cholinergic and dopaminergic systems in neuroendocrine regulation, Endocrinology, 101, 613, 10.1210/endo-101-2-613 Oida, 1984, Plasma lipoproteins of monosodium glutamate-induced obese rats, Int. J. Obes., 8, 385 Okamoto, 2011, Intensive insulin treatment induces insulin resistance in diabetic rats by impairing glucose metabolism-related mechanisms in muscle and liver, J. Endocrinol., 211, 55, 10.1530/JOE-11-0105 Price, 2012, SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function, Cell Metabol., 15, 675, 10.1016/j.cmet.2012.04.003 Santalucía, 2001, A novel functional co-operation between MyoD, MEF2 and TRalpha1 is sufficient for the induction of GLUT4 gene transcription, J. Mol. Biol., 314, 195, 10.1006/jmbi.2001.5091 Smith, 2008, CaMK activation during exercise is required for histone hyperacetylation and MEF2A binding at the MEF2 site on the Glut4 gene, Am. J. Physiol. Endocrinol. Metab., 295, E698, 10.1152/ajpendo.00747.2007 Stentz, 2007, Transcriptome and proteome expressions involved in insulin resistance in muscle and activated T-lymphocytes of patients with type 2 diabetes, Genom. Proteom. Bioinform., 5, 216, 10.1016/S1672-0229(08)60009-1 Tang, 2018, Metformin inhibits ovarian cancer via decreasing H3K27 trimethylation, Int. J. Oncol., 52, 1899 Tian, 2015, Histone deacetylase HDAC8 promotes insulin resistance and -catenin activation in NAFLD-associated hepatocellular carcinoma, Cancer Res., 75, 4803, 10.1158/0008-5472.CAN-14-3786 Tsao, 1996, Enhanced insulin action due to targeted GLUT4 overexpression exclusively in muscle, Diabetes, 45, 28, 10.2337/diab.45.1.28 Tsao, 1999, Prevention of insulin resistance and diabetes in mice heterozygous for GLUT4 ablation by transgenic complementation of GLUT4 in skeletal muscle, Diabetes, 48, 775, 10.2337/diabetes.48.4.775 Wan, 2018, Phosphorylation of EZH2 by AMPK suppresses PRC2 methyltransferase activity and oncogenic function, Mol. Cell, 69, 279, 10.1016/j.molcel.2017.12.024 Wang, 2016, Intra-uterine undernutrition amplifies age-associated glucose intolerance in pigs via altered DNA methylation at muscle GLUT4 promoter, Br. J. Nutr., 116, 390, 10.1017/S0007114516002166 Yamatsugu, 2018, Leading approaches in synthetic epigenetics for novel therapeutic strategies, Curr. Opin. Chem. Biol., 46, 10, 10.1016/j.cbpa.2018.03.011 Yan, 2014, HDAC inhibitor sodium butyrate augments the MEF2C enhancement of Nampt expression under hypoxia, Curr. Pharmaceut. Des., 20, 1604, 10.2174/13816128113199990544 Yonamine, 2017, Resveratrol improves glycemic control in type 2 diabetic obese mice by regulating glucose transporter expression in skeletal muscle and liver, Molecules, 22, 1180, 10.3390/molecules22071180 Yonamine, 2016, Resveratrol improves glycemic control in insulin-treated diabetic rats: participation of the hepatic territory, Nutr. Metab. (Lond)., 13, 44, 10.1186/s12986-016-0103-0 Zisman, 2000, Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance, Nat. Med., 6, 924, 10.1038/78693 Zorzano, 2005, Mechanisms regulating GLUT4 glucose transporter expression and glucose transport in skeletal muscle, Acta Physiol. Scand., 183, 43, 10.1111/j.1365-201X.2004.01380.x