Developments in inherent safety: A review of the progress during 2001–2011 and opportunities ahead

Process Safety and Environmental Protection - Tập 90 - Trang 389-403 - 2012
Rajagopalan Srinivasan1,2, Sathish Natarajan1
1Department of Chemical and Biomolecular Engg, National University of Singapore, 10 Kent Ridge Crescent, Singapore, 119260, Singapore
2Process Sciences and Modeling, Institute of Chemical and Engineering Science, 1 Pesek Road, Jurong Island, Singapore, 62783, Singapore

Tài liệu tham khảo

Abedi, 2005, Inherent safety evaluation in process plants—a comparison of methodologies, Cent. Eur. J. Chem., 3, 756, 10.2478/BF02475203 Abuswer, 2011, A quantitative risk management framework for dust and hybrid mixture explosions, J. Loss Prev. Process Ind., 10.1016/j.jlp.2011.08.010 Al-Mutairi, 2008, An optimization approach to the integration of inherently safer design and process scheduling, J. Loss Prev. Process Ind., 21, 543, 10.1016/j.jlp.2008.05.003 Amyotte, 2003, Reduction of dust explosion hazard by fuel substitution in power plants, Process Saf. Environ. Prot. Trans. Inst. Chem. Eng. Part B, 81, 457, 10.1205/095758203770866629 Amyotte, 2010, Prevention and mitigation of dust and hybrid mixture explosions, Process Saf. Prog., 29, 17, 10.1002/prs.10333 Amyotte, 2009, Application of inherent safety principles to dust explosion prevention and mitigation, Process Saf. Environ. Prot., 87, 35, 10.1016/j.psep.2008.06.007 Amyotte, 2007, Moderation of dust explosions, J. Loss Prev. Process Ind., 20, 675, 10.1016/j.jlp.2007.05.011 Amyotte, 2011, An analysis of CSB investigation reports concerning the hierarchy of controls, Process Safety Progress, 30, 261, 10.1002/prs.10461 Amyotte, 2010, Dust explosion causation, prevention and mitigation: An overview, J. Chem. Health Saf., 17, 15, 10.1016/j.jchas.2009.05.002 Arai, 2003, Nonflammable methyl nonafluorobutyl ether for electrolyte used in lithium secondary batteries, J. Electrochem. Soc., 150, A219, 10.1149/1.1538224 Ashford, 1993 Bajpai, 2005, Site security for chemical process industries, J. Loss Prev. Process Ind., 18, 301, 10.1016/j.jlp.2005.06.011 Banimostafa, 2011, Retrofit design of a pharmaceutical batch process considering green chemistry and engineering principles, 181 Benaïssa, 2008, Evaluation of an intensified continuous heat-exchanger reactor for inherently safer characteristics, J. Loss Prev. Process Ind., 21, 528, 10.1016/j.jlp.2008.04.004 Bennett, 2006, Major accidents: are we learning?, Hydrocarbon Eng., 11, 67 Boeh, 2011, Bottling a winning: clean-in-place solution, Water Wastewater Int., 26, 48 Bollinger, 1996 Bridges, 2009, Controlling risk during major capital projects, Chem. Eng. Prog., 105, 56 Bruggink, 2003, Concepts of nature in organic synthesis: cascade catalysis and multistep conversions in concert, Org. Process Res. Dev., 7, 622, 10.1021/op0340311 Carpenter, 2003, Toxic gas release caused by the thermal decomposition of a bulk powder blend containing sodium dichloroisocyanurate, Process Saf. Prog., 22, 75, 10.1002/prs.680220202 CCPS, 2009 Chang, 2009, Fire and explosion properties examinations of toluene–methanol mixtures approached to the minimum oxygen concentration, J. Therm. Anal. Calorim., 96, 741, 10.1007/s10973-009-0027-2 Chang, 2008, Flammability characteristics studies on toluene and methanol mixtures with different vapor mixing ratios at 1atm and 150°C, J. Therm. Anal. Calorim., 93, 183, 10.1007/s10973-007-8873-2 Chen, 2004, An inherently safer process of cyclohexane oxidation using pure oxygen—an example of how better process safety leads to better productivity, Process Saf. Prog., 23, 72, 10.1002/prs.10008 Cheng, 2008, Runaway reaction on tert-butyl peroxybenzoate by DSC tests, J. Therm. Anal. Calorim., 93, 121, 10.1007/s10973-007-8831-z Chia, 2003, Application of inherent safety challenge to an offshore platform design for a new gas field development—approaches and experiences, 257 Chiappetta, 2006, Analysis of safety aspects in a membrane reactor, Desalination, 193, 267, 10.1016/j.desal.2005.06.064 Chou, 2011, Effects of stirring rate for thermal runaway reaction in cumene hydroperoxide manufacturing process using calorimetric techniques, J. Therm. Anal. Calorim., 106, 243, 10.1007/s10973-011-1513-x Clark, 2008, Applying the ‘limitation of effects’ inherently safer processing strategy when siting and designing facilities, Process Saf. Prog., 27, 121, 10.1002/prs.10240 Considine, 2010, Enhancing offshore safety: a description of the offshore major accident risk (OMAR) model Cordella, 2009, Inherent safety of substances: Identification of accidental scenarios due to decomposition products, J. Loss Prev. Process Ind., 22, 455, 10.1016/j.jlp.2009.02.015 Cozzani, 2007, Prevention of domino effect: from active and passive strategies to inherently safer design, J. Hazard. Mater., 139, 209, 10.1016/j.jhazmat.2006.06.041 Crowl, 2011 CSB, 2007 D’Aquino, 2007, Update: solid-acid catalysts shape up for alkylation, Chem. Eng. Prog., 103, 8 Dahl, 2007, Toward greener nanosynthesis, Chem. Rev., 107, 2228, 10.1021/cr050943k Dermaut, 2007, Safety aspects of a cyanamide reaction: Inherent safe design through kinetic modelling and adiabatic testing, Org. Process Res. Dev., 11, 1126, 10.1021/op700166b Di Benedetto, 2010, Modelling the effect of particle size on dust explosions, Chem. Eng. Sci., 65, 772, 10.1016/j.ces.2009.09.029 Dow, 1994 Dowell, 2001, Critical safe operating parameters: never exceed limit and never deviate action, Process Saf. Prog., 20, 208, 10.1002/prs.680200310 Dunbobbin, 2004, Security vulnerability assessment in the chemical industry, Process Saf. Prog., 23, 214, 10.1002/prs.10037 Ebrahimi, 2009, Safety advantages of on-site microprocesses, Org. Process Res. Dev., 13, 965, 10.1021/op900079f Eckhoff, 2005, Current status and expected future trends in dust explosion research, J. Loss Prev. Process Ind., 18, 225, 10.1016/j.jlp.2005.06.012 Eckhoff, 2009, Dust explosion prevention and mitigation, status and developments in basic knowledge and in practical application, Int. J. Chem. Eng., 10.1155/2009/569825 Eckhoff, 2009, Understanding dust explosions. The role of powder science and technology, J. Loss Prev. Process Ind., 22, 105, 10.1016/j.jlp.2008.07.006 Edwards, 2005, Are we too risk-averse for inherent safety? An examination of current status and barriers to adoption, Process Saf. Environ. Prot., 83, 90, 10.1205/psep.04309 Edwards, 1993, Assessing the inherent safety of chemical process routes: is there a relation between plant costs and inherent safety?, Process Saf. Environ. Prot. Trans. Inst. Chem. Eng. Part B, 71, 252 Etowa, 2002, Quantification of inherent safety aspects of the Dow indices, J. Loss Prev. Process Ind., 15, 477, 10.1016/S0950-4230(02)00039-6 Falcke, 2011, The sustainability of clean coal technology: IGCC with/without CCS, Process Saf. Environ. Prot., 89, 41, 10.1016/j.psep.2010.08.002 Falke, 1994 First, 2010, Scenario identification and evaluation for layers of protection analysis, J. Loss Prev. Process Ind., 23, 705, 10.1016/j.jlp.2010.07.008 French, 1996, Inherent safety, health, and environmental (SHE) reviews, Process Saf. Prog., 15, 48, 10.1002/prs.680150112 García-Serna, 2007, Green HAZOP analysis: incorporating green engineering into design, assessment and implementation of chemical processes, Green Chem., 9, 111, 10.1039/B518092A Gentile, 2003, Development of a fuzzy logic-based inherent safety index, Process Saf. Environ. Prot. Trans. Inst. Chem. Eng. Part B, 81, 444, 10.1205/095758203770866610 Gilmour, 2010, Floating LNG: shell's recent history and current approach Gupta, 2003, A simple graphical method for measuring inherent safety, J. Hazard. Mater., 104, 15, 10.1016/S0304-3894(03)00231-0 Hansson, 2010, Promoting inherent safety, Process Saf. Environ. Prot., 88, 168, 10.1016/j.psep.2010.02.003 Hassim, 2006, Development of a methodology for assessing inherent occupational health hazards, Process Saf. Environ. Prot., 84, 378, 10.1205/psep.04412 Hassim, 2010, Inherent occupational health assessment during basic engineering stage, J. Loss Prev. Process Ind., 23, 260, 10.1016/j.jlp.2009.10.006 Hassim, 2010, Inherent occupational health assessment during preliminary design stage, J. Loss Prev. Process Ind., 23, 476, 10.1016/j.jlp.2009.12.004 Hassim, 2010, Inherent occupational health assessment during process research and development stage, J. Loss Prev. Process Ind., 23, 127, 10.1016/j.jlp.2009.06.009 Hassim, 2010, Occupational chemical exposure and risk estimation in process development and design, Process Saf. Environ. Prot., 88, 225, 10.1016/j.psep.2010.03.011 Heikkila, A.M., 1999. Inherent safety in process plant design: an index-based approach. Unpublished doctoral, Technica Research Centre of Finland, Helsinki University of Technology (Espoo, Finland), Espoo. Heikkila, 1996, Safety considerations in process synthesis, Comput. Chem. Eng., 20, S115, 10.1016/0098-1354(96)00030-0 Heikkila, 1998 Hendershot, 2006, An overview of inherently safer design, Process Saf. Prog., 25, 98, 10.1002/prs.10121 Hendershot, 2007, Tell me why, J. Hazard. Mater., 142, 582, 10.1016/j.jhazmat.2006.06.128 Hendershot, 2010, A summary of inherently safer technology, Process Saf. Prog., 29, 389, 10.1002/prs.10395 Hendershot, 2011, Inherently safer design—not only about reducing consequences!, Process Saf. Prog., 30, 351, 10.1002/prs.10469 Hendershot, 2006, Implementing inherently safer design in an existing plant, Process Saf. Prog., 25, 52, 10.1002/prs.10117 Hess, 2009, Inherent safety, Chem. Eng. News, 87, 34, 10.1021/cen-v087n020.p034 Huser, 2009, A CFD based approach to the correlation of maximum explosion overpressure to process plant parameters, J. Loss Prev. Process Ind., 22, 324, 10.1016/j.jlp.2008.12.001 Johnson, 2011, Getting the toxics out, Chem. Eng. News, 89, 31, 10.1021/cen-v089n008.p031 Kestenbaum, 2002, Silver-catalyzed oxidation of ethylene to ethylene oxide in a microreaction system, Ind. Eng. Chem. Res., 41, 710, 10.1021/ie010306u Khan, 2002, Inherent safety in offshore oil and gas activities: a review of the present status and future directions, J. Loss Prev. Process Ind., 15, 279, 10.1016/S0950-4230(02)00009-8 Khan, 2004, Integrated inherent safety index (I2SI): a tool for inherent safety evaluation, Process Saf. Prog., 23, 136, 10.1002/prs.10015 Khan, 2005, I2SI: a comprehensive quantitative tool for inherent safety and cost evaluation, J. Loss Prev. Process Ind., 18, 310, 10.1016/j.jlp.2005.06.022 Khan, 2003, Evaluation of available indices for inherently safer design options, Process Saf. Prog., 22, 83, 10.1002/prs.680220203 Khan, 2002, Risk-based process safety assessment and control measures design for offshore process facilities, J. Hazard. Mater., 94, 1, 10.1016/S0304-3894(02)00004-3 Klais, 2009, Guidance on safety/health for process intensification including MS Design: Part II. Explosion hazards, Chem. Eng. Technol., 32, 1966, 10.1002/ceat.200900217 Kletz, 1978, What you dont have, can’t leak, Chem. Ind., 287 Kletz, 1985, Inherently safer plants, Plant Oper. Prog., 4, 164, 10.1002/prsb.720040311 Kletz, 1998 Koban, 2011, Dispersion modeling of leaks of low global warming potential refrigerant HFO-1234yf in an automobile garage, Process Saf. Prog., 30, 27, 10.1002/prs.10415 Koc, 2011, Process safety aspects in water-gas-shift (WGS) membrane reactors used for pure hydrogen production, J. Loss Prev. Process Ind., 24, 852, 10.1016/j.jlp.2011.06.012 Koller, 2001, Comparison of methods suitable for assessing the hazard potential of chemical processes during early design phases, Process Saf. Environ. Prot., 79, 157, 10.1205/09575820150511939 Landucci, 2008, Inherent safety key performance indicators for hydrogen storage systems, J. Hazard. Mater., 159, 554, 10.1016/j.jhazmat.2008.02.080 Lawrence, D., 1996. Quantifying the inherent safety of chemical process routes. Unpublished Doctorol Thesis, Loughborough University of Technology, UK. Leffler, 2007, Ambient intelligence, ABB Rev., 53 Leong, 2008, Inherent safety index module (ISIM) to assess inherent safety level during preliminary design stage, Process Saf. Environ. Prot., 86, 113, 10.1016/j.psep.2007.10.016 Leong, 2009, Process route index (PRI) to assess level of explosiveness for inherent safety quantification, J. Loss Prev. Process Ind., 22, 216, 10.1016/j.jlp.2008.12.008 Li, 2011, Incorporating exergy analysis and inherent safety analysis for sustainability assessment of biofuels, Ind. Eng. Chem. Res., 50, 2981, 10.1021/ie101660q Li, M., Subramaniam, B., Niu, F., Zuo, X., & Busch, D. (2009). Development and modeling of a novel spray reactor for p-xylene oxidation to terephthalic acid. In 2009 AIChE Annual Meeting. Nashville, TN. Liaw, 2008, Flash-point prediction for binary partially miscible aqueous–organic mixtures, Chem. Eng. Sci., 63, 4543, 10.1016/j.ces.2008.06.005 Liaw, 2010, Flash point for ternary partially miscible mixtures of flammable solvents, J. Chem. Eng. Data, 55, 134, 10.1021/je900287r Liaw, 2010, Flash-point measurements and modeling for ternary partially miscible aqueous–organic mixtures, J. Chem. Eng. Data, 55, 3451, 10.1021/je100163q Liebner, 2011, Are micro reactors inherently safe? An investigation of gas phase explosion propagation limits on ethene mixtures, Process Saf. Environ. Prot. Limbach, 2009, Physico-chemical differences between particle- and molecule-derived toxicity: can we make inherently safe nanoparticles?, Chimia, 63, 38, 10.2533/chimia.2009.38 Lin, 2009, A comparison of thermal decomposition energy and nitrogen content of nitrocellulose in non-fat process of linters by DSC and EA, J. Therm. Anal. Calorim., 95, 547, 10.1007/s10973-008-9463-7 Lin, 2010, Modeling thermal decomposition kinetic algorithms on CL-20 and HMX, Int. J. Chem. React. Eng., 8 Liu, 2009, Recovery of indium from etching wastewater using supercritical carbon dioxide extraction, J. Hazard. Mater., 172, 744, 10.1016/j.jhazmat.2009.07.098 Lopez, 2005, Process development of an inherently safer oxidation: synthesis of 2-chloro-6-methylbenzoic acid in the R411 manufacturing process, Org. Process Res. Dev., 9, 1003, 10.1021/op050083+ Louvar, 2007, Education materials for universities and industry, Process Saf. Prog., 26, 85, 10.1002/prs.10196 Lu, 2011, Prediction of the reactivity hazards for organic peroxides using the QSPR approach, Ind. Eng. Chem. Res., 50, 1515, 10.1021/ie100833m Lu, 2010, Key observations of cumene hydroperoxide concentration on runaway reaction parameters, Thermochim. Acta, 501, 65, 10.1016/j.tca.2010.01.011 Luyben, 2004, Dynamic disadvantages of intensification in inherently safer process design, Ind. Eng. Chem. Res., 43, 384, 10.1021/ie030266p Maestri, 2007, Safe and productive operation of homogeneous semibatch reactors involving autocatalytic reactions with arbitrary reaction order, Ind. Eng. Chem. Res., 46, 5333, 10.1021/ie070427f Mannan, 2005 Mansfield, 1997, INSET toolkit stages III and IVs process front end and detailed design Marsh, 2001 McKeon-Slattery, 2010, Will IST stall CFATS reauthorization?, Chem. Eng. Prog., 106, 6 Meel, 2006, Plant-specific dynamic failure assessment using Bayesian theory, Chem. Eng. Sci., 61, 7036, 10.1016/j.ces.2006.07.007 Meel, 2008, Real-time risk analysis of safety systems, Comput. Chem. Eng., 32, 827, 10.1016/j.compchemeng.2007.03.006 Meel, 2006, Game theoretic approach to multiobjective designs: focus on inherent safety, AIChE J., 52, 228, 10.1002/aic.10635 Mohd Shariff, 2006, Inherent safety tool for explosion consequences study, J. Loss Prev. Process Ind., 19, 409, 10.1016/j.jlp.2005.10.008 Molga, 2007, Runaway prevention in liquid-phase homogeneous semibatch reactors, Chem. Eng. Sci., 62, 5074, 10.1016/j.ces.2007.03.016 Moradi, 2008, vol. 25, 127 Murphy, 2011, The black swan: LOPA and inherent safety cannot prevent all rare and catastrophic incidents, Process Saf. Prog., 30, 202, 10.1002/prs.10462 Myers, 2008, Reducing aluminum dust explosion hazards: case study of dust inerting in an aluminum buffing operation, J. Hazard. Mater., 159, 72, 10.1016/j.jhazmat.2008.02.106 Nair, 2009, Hazardous material storage installations: steps to address concerns on safety and build public confidence, J. Inst. Eng. (India): Chem. Eng. Div., 90, 17 Palaniappan, 2002, A material-centric methodology for developing inherently safer environmentally benign processes, Comput. Chem. Eng., 26, 757, 10.1016/S0098-1354(01)00786-4 Palaniappan, 2002, Expert system for the design of inherently safer processes. 1. Route selection stage, Ind. Eng. Chem. Res., 41, 6698, 10.1021/ie020175c Palaniappan, 2004, Selection of inherently safer process routes: a case study, Chem. Eng. Process.: Process Intensification, 43, 647, 10.1016/j.cep.2002.12.001 Palaniappan, 2002, Expert system for the design of inherently safer processes. 2. Flowsheet development stage, Ind. Eng. Chem. Res., 41, 6711, 10.1021/ie0201765 Papadaki, 2008, Inherent safety, ethics and human error, J. Hazard. Mater., 150, 826, 10.1016/j.jhazmat.2007.09.121 Papadaki, 2005, Catalytic decomposition of hydrogen peroxide in the presence of alkylpyridines: runaway scenarios studies, J. Loss Prev. Process Ind., 18, 384, 10.1016/j.jlp.2005.06.024 Patel, 2010, Inherently safer design of solvent processes at the conceptual stage: practical application for substitution, J. Loss Prev. Process Ind., 23, 483, 10.1016/j.jlp.2010.03.002 Pekalski, 2005, A review of explosion prevention and protection systems suitable as ultimate layer of protection in chemical process installations, Process Saf. Environ. Prot., 83, 1, 10.1205/psep.04023 Pula, 2007, A model for estimating the probability of missile impact: missiles originating from bursting horizontal cylindrical vessels, Process Saf. Prog., 26, 129, 10.1002/prs.10178 Rahman, 2005, Comparison of inherent safety indices in process concept evaluation, J. Loss Prev. Process Ind., 18, 327, 10.1016/j.jlp.2005.06.015 Rathnayaka, 2011, SHIPP methodology: Predictive accident modeling approach. Part I: Methodology and model description, Process Saf. Environ. Prot., 89, 151, 10.1016/j.psep.2011.01.002 Reisch, 2009, Inherently safer water purification, Chem. Eng. News, 87 Rogers, 2004, Upgrading an alkoxylation facility: the value of calorimetric studies, Process Saf. Environ. Prot., 82, 12, 10.1205/095758204322777624 Rusli, 2010, Qualitative assessment for inherently safer design (QAISD) at preliminary design stage, J. Loss Prev. Process Ind., 23, 157, 10.1016/j.jlp.2009.07.005 Sawyer, 2010, Regulating inherent safety Contra Costa County's industrial safety ordinance Schabel, 1997, INSET toolkit stages I and IIs route selection and optimisation Scheffler, 1996, Inherently safer latex plants, Process Saf. Prog., 15, 11, 10.1002/prs.680150107 Schweitzer, 2010, Thermal runaway analysis of a three-phase reactor for LCO hydrotreatment, Chem. Eng. Sci., 65, 313, 10.1016/j.ces.2009.07.012 Seay, 2008, Incorporating risk assessment and inherently safer design practices: into chemical engineering education, Chem. Eng. Educ., 42, 141 Shah, 2009, Inherent safety analysis of a propane precooled gas-phase liquified natural gas process, Ind. Eng. Chem. Res., 48, 4917, 10.1021/ie8015939 Shah, 2003, A hierarchical approach for the evaluation of chemical process aspects from the perspective of inherent safety, Process Saf. Environ. Prot. Trans. Inst. Chem. Eng. Part B, 81, 430, 10.1205/095758203770866601 Shah, 2005, Assessment of chemical process hazards in early design stages, J. Loss Prev. Process Ind., 18, 335, 10.1016/j.jlp.2005.06.016 Shariff, 2009, Inherent risk assessment—a new concept to evaluate risk in preliminary design stage, Process Saf. Environ. Prot., 87, 371, 10.1016/j.psep.2009.08.004 Shariff, 2010, Toxic release consequence analysis tool (TORCAT) for inherently safer design plant, J. Hazard. Mater., 182, 394, 10.1016/j.jhazmat.2010.06.046 Sharratt, 2003, Novel process design methods to access safer processing options Srinivasan, 2003, A decision support database for inherently safer design, 287 Srinivasan, 2006, Application of the TRIZ creativity enhancement approach to design of inherently safer chemical processes, Chem. Eng. Process. Process Intensification, 45, 507, 10.1016/j.cep.2005.11.009 Srinivasan, 2008, A statistical approach for evaluating inherent benign-ness of chemical process routes in early design stages, Process Saf. Environ. Prot., 86, 163, 10.1016/j.psep.2007.10.011 Steyer, 2008, A novel reactive distillation process for the indirect hydration of cyclohexene to cyclohexanol using a reactive entrainer, Ind. Eng. Chem. Res., 47, 9581, 10.1021/ie800303k Stolte, 2007, Effects of different head groups and functionalised side chains on the aquatic toxicity of ionic liquids, Green Chem., 9, 1170, 10.1039/b711119c Study, 2007, A real-life example of choosing an inherently safer process option, J. Hazard. Mater., 142, 771, 10.1016/j.jhazmat.2006.06.097 Suardin, 2007, The integration of Dow's fire and explosion index (F&EI) into process design and optimization to achieve inherently safer design, J. Loss Prev. Process Ind., 20, 79, 10.1016/j.jlp.2006.10.006 Subramaniam, 2010, Gas-expanded liquids for sustainable catalysis and novel materials: Recent advances, Coord. Chem. Rev., 254, 1843, 10.1016/j.ccr.2009.12.009 Summers, 2008, Alternative approach to wellhead flowline-pressure protection, J. Petrol. Technol., 60, 69, 10.2118/0208-0069-JPT Sutton, 2010 Takriff, 2010, Integration of Inherent Safety assessment into process simulation Tanabe, 2011, Risk reduction concept to provide design criteria for emergency systems for onshore LNG plants, J. Loss Prev. Process Ind., 24, 383, 10.1016/j.jlp.2011.02.002 Thayer, 2005, Harnessing microreactions, Chem. Eng. News, 83, 43, 10.1021/cen-v083n022.p043 Tugnoli, 2007, A consequence based approach to the quantitative assessment of inherent safety, AIChE J., 53, 3171, 10.1002/aic.11315 Tugnoli, 2008, Safety assessment in plant layout design using indexing approach: implementing inherent safety perspective. Part 1—Guideword applicability and method description, J. Hazard. Mater., 160, 100, 10.1016/j.jhazmat.2008.02.089 Tugnoli, 2008, Safety assessment in plant layout design using indexing approach: Implementing inherent safety perspective. Part 2. Domino Hazard Index and case study, J. Hazard. Mater., 160, 110, 10.1016/j.jhazmat.2008.02.091 Tugnoli, 2009, Key performance indicators for inherent safety: application to the hydrogen supply chain, Process Saf. Prog., 28, 156, 10.1002/prs.10303 Tugnoli, 2010, LNG regasification terminals: Comparing the inherent safety performance of innovative technologies Tugnoli, 2011, Implementation of sustainability drivers in the design of industrial chemical processes, AIChE J., 57, 3063, 10.1002/aic.12497 Vaughen, 2011, Improving operational discipline to prevent loss of containment incidents, Process Saf. Prog., 30, 216, 10.1002/prs.10430 Wang, 2009, Singularity theory based stability analysis of reacting systems, Computer Aided Chemical Engineering, 27, 645, 10.1016/S1570-7946(09)70328-1 Wang, 2011, Analysis of the stability and controllability of chemical processes, Comput. Chem. Eng., 35, 1101, 10.1016/j.compchemeng.2010.12.011 Westerterp, 2004, No more runaways in fine chemical reactors, Ind. Eng. Chem. Res., 43, 4585, 10.1021/ie030725m Wu, 2011, Thermal hazard evaluation of tert-butyl peroxide using non-isothermal and adiabatic calorimetric approaches, J. Therm. Anal. Calorim., 1 You, 2009, Thermal explosion and runaway reaction simulation of lauroyl peroxide by DSC tests, J. Therm. Anal. Calorim., 96, 777, 10.1007/s10973-009-0025-4 Yuan, 2011, Controllability analysis for the liquid-phase catalytic oxidation of toluene to benzoic acid, Chem. Eng. Sci., 66, 5137, 10.1016/j.ces.2011.07.005 Yuan, 2009, Operating zone segregation of chemical reaction systems based on stability and non-minimum phase behavior analysis, Chem. Eng. J., 155, 304, 10.1016/j.cej.2009.06.036 Zwetsloot, 2003, The feasibility of encouraging inherently safer production in industrial firms, Saf. Sci., 41, 219, 10.1016/S0925-7535(02)00003-6