Development of the PREDS score to predict in-hospital mortality of patients with Ebola virus disease under advanced supportive care: Results from the EVISTA cohort in the Democratic Republic of the Congo

eClinicalMedicine - Tập 54 - Trang 101699 - 2022
Marie Jaspard1,2, Sabue Mulangu3, Sylvain Juchet1,2, Beatrice Serra1,2, Ibrahim Dicko1, Hans-Joeg Lang1, Baweye Mayoum Baka1, Gaston Musemakweli Komanda4, Jeremie Muhindo Katsavara4, Patricia Kabuni5, Fabrice Mbika Mambu3, Margaux Isnard6, Christophe Vanhecke7, Alexia Letord8, Ibrahima Dieye9, Oscar Patterson-Lomba9, Olivier Tshiani Mbaya3, Fiston Isekusu5, Donatien Mangala5, Jean Luc Biampata3
1Alliance for International Medical Action (ALIMA), Dakar, Senegal
2University of Bordeaux, National Institute for Health and Medical Research (Inserm), Research Institute for Sustainable Development (IRD), Bordeaux Population Health Center, UMR 1219, Bordeaux, France
3National Biomedical Research Institute (INRB), Kinshasa, Democratic Republic of the Congo
4Beni General Hospital, North Kivu province, Democratic Republic of the Congo
5Kinshasa University Hospital, Democratic Republic of the Congo
6Intensive Care Unit, Savoie Hospital, France
7Internal Medicine Department, West Réunion Hospital, Réunion, France
8Surgical Intensive Care Unit, Henri Mondor University Hospital, Créteil, France
9Analysis Group, Inc., Boston, MA 02199, USA

Tài liệu tham khảo

10th Ebola outbreak in the Democratic Republic of the Congo declared over; vigilance against flare-ups and support for survivors must continue.https://www.who.int/news/item/25-06-2020-10th-ebola-outbreak-in-the-democratic-republic-of-the-congo-declared-over-vigilance-against-flare-ups-and-support-for-survivors-must-continue. Accessed 21 July 2022. Henao-Restrepo, 2017, Efficacy and effectiveness of an rVSV-vectored vaccine in preventing Ebola virus disease: final results from the Guinea ring vaccination, open-label, cluster-randomised trial (Ebola Ça Suffit!), Lancet Lond Engl, 389, 505, 10.1016/S0140-6736(16)32621-6 Coller, 2017, Clinical development of a recombinant Ebola vaccine in the midst of an unprecedented epidemic, Vaccine, 35, 4465, 10.1016/j.vaccine.2017.05.097 Mulangu, 2019, A randomized, controlled trial of Ebola virus disease therapeutics, N Engl J Med, 381, 2293, 10.1056/NEJMoa1910993 Fischer, 2019, Shifting the paradigm - applying universal standards of care to ebola virus disease, N Engl J Med, 380, 1389, 10.1056/NEJMp1817070 Lamontagne, 2018, Evidence-based guidelines for supportive care of patients with Ebola virus disease, Lancet Lond Engl, 391, 700, 10.1016/S0140-6736(17)31795-6 Leligdowicz, 2016, Ebola virus disease and critical illness, Crit Care Lond Engl, 20, 217, 10.1186/s13054-016-1325-2 Langer, 2018, Intensive care support and clinical outcomes of patients with Ebola virus disease (EVD) in West Africa, Intensive Care Med, 44, 1266, 10.1007/s00134-018-5308-4 Fowler, 2014, Caring for critically ill patients with ebola virus disease. Perspectives from West Africa, Am J Respir Crit Care Med, 190, 733, 10.1164/rccm.201408-1514CP Lamontagne, 2014, Doing today's work superbly well–treating Ebola with current tools, N Engl J Med, 371, 1565, 10.1056/NEJMp1411310 Optimized supportive care for Ebola virus disease.https://www.who.int/publications-detail/optimized-supportive-care-for-ebola-virus-disease. Accessed 6 January 2020. National Early Warning Score (NEWS) 2. RCP Lond. 2017; published online Dec 19. https://www.rcplondon.ac.uk/projects/outputs/national-early-warning-score-news-2. Accessed 17 September 2021. Lamontagne, 2019, The evolution of supportive care for Ebola virus disease, Lancet Lond Engl, 393, 620, 10.1016/S0140-6736(19)30242-9 Malvy, 2019, Ebola virus disease, Lancet Lond Engl, 393, 936, 10.1016/S0140-6736(18)33132-5 Sullivan, 2004, Presentation of multivariate data for clinical use: the Framingham study risk score functions, Stat Med, 23, 1631, 10.1002/sim.1742 Buuren, 2011, MICE: multivariate imputation by chained equations in R, J Stat Softw, 45, 10.18637/jss.v045.i03 Marshall, 2010, Comparison of imputation methods for handling missing covariate data when fitting a Cox proportional hazards model: a resampling study, BMC Med Res Methodol, 10, 112, 10.1186/1471-2288-10-112 Jacob, 2020, Ebola virus disease, Nat Rev Dis Primer, 6, 13, 10.1038/s41572-020-0147-3 Bah, 2015, Clinical presentation of patients with Ebola virus disease in Conakry, Guinea, N Engl J Med, 372, 40, 10.1056/NEJMoa1411249 Mobula, 2018, Clinical manifestations and modes of death among patients with Ebola virus disease, Monrovia, Liberia, 2014, Am J Trop Med Hyg, 98, 1186, 10.4269/ajtmh.17-0090 Schieffelin, 2014, Clinical illness and outcomes in patients with Ebola in Sierra Leone, N Engl J Med, 371, 2092, 10.1056/NEJMoa1411680 Lado, 2015, Clinical features of patients isolated for suspected Ebola virus disease at Connaught Hospital, Freetown, Sierra Leone: a retrospective cohort study, Lancet Infect Dis, 15, 1024, 10.1016/S1473-3099(15)00137-1 van Griensven, 2016, Electrolyte and metabolic disturbances in Ebola patients during a clinical trial, Guinea, 2015, Emerg Infect Dis, 22, 10.3201/eid2212.161136 Hunt, 2015, Clinical presentation, biochemical, and haematological parameters and their association with outcome in patients with Ebola virus disease: an observational cohort study, Lancet Infect Dis, 15, 1292, 10.1016/S1473-3099(15)00144-9 Loignon, 2018, Barriers to supportive care during the Ebola virus disease outbreak in West Africa: results of a qualitative study, PloS One, 13, 10.1371/journal.pone.0201091 Iversen, 2020, Recent successes in therapeutics for Ebola virus disease: no time for complacency, Lancet Infect Dis, 20, e231, 10.1016/S1473-3099(20)30282-6 Uyeki, 2016, Clinical Management of Ebola virus disease in the United States and Europe, N Engl J Med, 374, 636, 10.1056/NEJMoa1504874 Kangbai, 2020, Severity score for predicting in-facility Ebola treatment outcome, Ann Epidemiol, 49, 68, 10.1016/j.annepidem.2020.07.017 Hartley, 2017, Predicting Ebola severity: a clinical prioritization score for Ebola virus disease, PLoS Negl Trop Dis, 11 Duvignaud, 2021, Lassa fever outcomes and prognostic factors in Nigeria (LASCOPE): a prospective cohort study, Lancet Glob Health, 9, e469, 10.1016/S2214-109X(20)30518-0