Development of a High Throughput Screening Assay for Mitochondrial Membrane Potential in Living Cells

Mitchell, 1977, Vectorial chemiosmotic processes, Annu Rev' Biochem, 46, 996, 10.1146/annurev.bi.46.070177.005024

Chen, 1988, Mitochondrial membrane potential in living cells, Annu Rev Cell Biol, 4, 155, 10.1146/annurev.cb.04.110188.001103

Sugrue, 2001, Mitochondrial membrane potential in aging cells, Biol Signals Recept, 10, 176, 10.1159/000046886

Hagen, 1998, Mitochondrial decay in aging: reversal through supplementation of acetyl-L-camitine and N-tert-butyl-alpha-phenyl-nitrone, Ann N Y Acad Sci, 854, 214, 10.1111/j.1749-6632.1998.tb09904.x

Harper, 1998, Age-related increase in mitochondrial proton leak and decrease in ATP turnover reactions in mouse hepatocytes, Am J Physiol, 275, E197

Sugrue, 1999, Reduced mitochondrial membrane potential and altered responsiveness of a mitochondrial membrane megachannel in p53-induced senescence, Biochem Biophys Res Commun, 261, 123, 10.1006/bbrc.1999.0984

Susin, 1998, Mitochondria as regulators of apoptosis: doubt no more, Biochim Biophys Acta, 1366, 151, 10.1016/S0005-2728(98)00110-8

Zamzami, 1998, Subcellular and submitochondrial mode of action of Bcl-2-like oncoproteins, Oncogene, 16, 2265, 10.1038/sj.onc.1201989

Duchen, 2000, Mitochondria and calcium: from cell signalling to cell death, J Physiol, 529, 57, 10.1111/j.1469-7793.2000.00057.x

Galati, 2000, Cancer chemoprevention and apoptosis mechanisms induced by dietary polyphenolics, Drug Metab Drug Interact, 17, 311, 10.1515/DMDI.2000.17.1-4.311

Nicholls, 1984, Thermogenic mechanisms in brown fat, Physiol Rev, 64, 1, 10.1152/physrev.1984.64.1.1

Klingenberg, 1990, Mechanism and evolution of the uncoupling protein of brown adipose tissue, Trends Biochem Sci, 15, 8, 10.1016/0968-0004(90)90194-G

Zamzami, 2000, Quantitation of mitochondrial transmembrane potential in cells and in isolated mitochondria, Methods Enzymol, 322, 208, 10.1016/S0076-6879(00)22021-1

Nicholls, 2000, Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts, Trends Neurosci, 23, 166, 10.1016/S0166-2236(99)01534-9

Scaduto, 1999, Measurement of mitochondrial membrane potential using fluorescent rhodamine derivatives, Biophys J, 76, 469, 10.1016/S0006-3495(99)77214-0

Haugland, 1996, Probes for membrane potential, 585

Blattner, 2001, Screening assays for the mitochondrial permeability transition using a fluorescence multiwell plate reader, Anal Biochem, 295, 220, 10.1006/abio.2001.5219

Shimizu, 1998, Bcl-2 prevents apoptotic mitochondrial dysfunction by regulating proton flux, Proc Natl Acad Sci USA, 95, 1455, 10.1073/pnas.95.4.1455

Loew, 1994, Physiological cytosolic Ca2l transients evoke concurrent mitochondrial depolarizations, Proc Natl Acad Sci U S A, 91, 12579, 10.1073/pnas.91.26.12579

Krysko, 2001, Mitochondrial transmembrane potential changes support the concept of mitochondrial heterogeneity during apoptosis, J Histochem Cytochem, 49, 1277, 10.1177/002215540104901010

Kindmark, 2001, Glucose-induced oscillations in cytoplasmic free Ca2+ concentration precede oscillations in mitochondrial membrane potential in the pancreatic beta-cell, J Biol Chem, 276, 34530, 10.1074/jbc.M102492200

Floryk, 1999, Tetramethyl rhodamine methyl ester (TMRM) is suitable for cytofluorometric measurements of mitochondrial membrane potential in cells treated with digitonin, Biosci Rep, 19, 27, 10.1023/A:1020193906974

Sureda, 1997, Mitochondrial membrane potential measurement in rat cerebellar neurons by flow cytometry, Cytometry, 28, 74, 10.1002/(SICI)1097-0320(19970501)28:1<74::AID-CYTO9>3.0.CO;2-H

Farrelly, 2001, A high-throughput assay for mitochondrial membrane potential in permeabilized yeast cells, Anal Biochem, 293, 269, 10.1006/abio.2001.5139

Nicholls, 1984, Thermogenic mechanisms in brown fat, Physiol Rev, 64, 1, 10.1152/physrev.1984.64.1.1

Klingenberg, 1999, Structure and function of the uncoupling protein from brown adipose tissue, Biochim Biophys Acta, 1415, 271, 10.1016/S0005-2736(98)00232-6

Yu, 1997, Mediation of neuronal apoptosis by enhancement of outward potassium current, Science, 278, 114, 10.1126/science.278.5335.114

Farkas, 1989, Simultaneous imaging of cell and mitochondrial membrane potentials, Biophys J, 56, 1053, 10.1016/S0006-3495(89)82754-7

Davis, 1985, Mitochondrial and plasma membrane potentials cause unusual accumulation and retention of rhodamine 123 by human breast adenocarcinoma-derived MCF-7 cells, J Biol Chem, 260, 13844, 10.1016/S0021-9258(17)38802-6

Krohn, 1999, Mitochondrial depolarization is not required for neuronal apoptosis, J Neurosci, 19, 7394, 10.1523/JNEUROSCI.19-17-07394.1999

Ward, 2000, Mitochondrial membrane potential and glutamate excitotoxicity in cultured cerebellar granule cells, J Neurosci, 20, 7208, 10.1523/JNEUROSCI.20-19-07208.2000

Zhang, 1999, A simple statistical parameter for use in evaluation and validation of high throughput screening assays, J Biomol Screen, 4, 67, 10.1177/108705719900400206

Ziegler, 1991, CELISA for rapid screening of monoclonal islet cell surface antibodies using living rat insulinoma cells as target, Diabetes Res, 16, 41

Wallace, 1999, Mitochondrial diseases in man and mouse, Science, 283, 1482, 10.1126/science.283.5407.1482

Howell, 1999, Human mitochondrial diseases: answering questions and questioning answers, Int Rev Cytol, 186, 49, 10.1016/S0074-7696(08)61051-7

Hanna, 1999, Genetics and molecular pathogenesis of mitochondrial respiratory chain diseases, Cell Mol Life Sci, 55, 691, 10.1007/s000180050327

Schapira, 1999, Mitochondrial myopathies and encephalomyopathies, Eur J Clin Invest, 29, 886, 10.1046/j.1365-2362.1999.00540.x