Determination of the relative contributions of the diselenide and selenol forms of ebselen in the mechanism of its glutathione peroxidase-like activity
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Ebselen European Patent 44,1971; Ger. 3,027,073; Jpn. K-8256,427; US. 4,352,799. A. Nattermann and Cie GmbH, Köln, Germany.
Muller, 1984, A novel biologically active compound 1. Glutathione peroxidase activity in vitro and antioxidant capacity of PZ51 (ebselen), Biochem. Pharmacol., 33, 3235
Hayashi, 1986, Inhibitory effects of ebselen on lipid peroxidation in isolated rat liver microsomes, Free Rad. Res. Commun., 2, 179, 10.3109/10715768609088070
Fisher, 1987, Mechanism of the catalytic reduction of hydroperoxides by ebselen: A selenium 77 NMR study, Bull. Soc. Chim. Belg., 96, 757, 10.1002/bscb.19870961006
Haenen, 1990, Mechanism of the reaction of ebselen with endogenous thiols. Dihydroplipoate is a better substrate than glutathione in the peroxidase activity of ebselen, Mol. Pharmacol., 37, 412
Mairoino, 1988, Kinetic mechanism and substrate specificity of the glutathione peroxidase activity of ebselen (PZ51), Biochem. Pharmacol., 37, 2267, 10.1016/0006-2952(88)90591-6
Cotgreave, 1992, Characterisation and quantitation of a selenol intermediate in the reaction of ebselen with thiols, Chem.-Biol. Interact., 84, 67, 10.1016/0009-2797(92)90121-Z
Engman, 1989, Expedient synthesis of ebselen and related compounds, J. Org. Chem., 54, 2964, 10.1021/jo00273a035