Determination of residual levels of metrafenone in lettuce grown under greenhouse conditions using gas chromatography with a micro-electron capture detector

Applied Biological Chemistry - Tập 59 - Trang 43-49 - 2016
Md. Humayun Kabir1, A. M. Abd El-Aty2,3, So Jeong Im1, Md. Musfiqur Rahman1, Sung-Woo Kim1, Waziha Farha1, Jeong-Heui Choi1, Da-I Jung1, Young-Jun Lee1, Troung Lieu1, Ho-Chul Shin2, Geon-Jae Im4, Su-Myeong Hong4, Jae-Han Shim1
1Biotechnology Research Institute, Chonnam National University, Gwangju, Republic of Korea
2Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea
3Department of Pharmacology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt
4Department of Agro-food Safety, National Academy of Agriculture Science, Rural Development Administration, Wanju, Republic of Korea

Tóm tắt

The current study was carried out to detect metrafenone residues and estimate the half-lives in lettuce grown under greenhouse conditions using gas chromatography with a micro-electron capture detector. Metrafenone was applied in two and three doses (with a 7-day interval) to two different sites in Naju (distance between sites 1 and 2 = 6.5 km) in different seasons (spring and autumn). Samples were extracted with acetone and matrix components were purified using a silica solid-phase extraction (SPE) cartridge. The calibration curve over the concentration range of 0.02–5.0 mg/L was linear with a determination coefficient (R 2) = 0.9993. The limits of detection and quantification were 0.003 and 0.01 mg/L, respectively. Recoveries at two fortification levels (0.1 and 0.5 mg/kg) ranged from 78.5 to 113.3 % with a relative standard deviation <8 %. The calculated half-lives were 2.3 and 2.2 days and 4.9 and 5.0 days for the double and triple doses at sites 1 and 2, respectively. These results suggest that the method is effective and sensitive for the determination of metrafenone residues in field-incurred lettuce samples, and the difference in the reported half-lives is due to seasonal variation.

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