Determination of nociceptin–orphanin FQ metabolites by capillary LC–MS

Suder, 1999, Metabolic fate of nociceptin/orphanin FQ in the rat spinal cord and biological activity of metabolites, Peptides, 20, 239, 10.1016/S0196-9781(98)00165-X Smoluch, 1999, Metabolism of nociceptin/orphanin FQ in the spinal cord, studied by LC-ESI MS, Protein and Peptide Lett., 6, 49 Sandin, 1997, Differential processing of dynorphins insubstantia nigra, striatum and hippocampus, Peptides, 18, 949, 10.1016/S0196-9781(97)00025-9 Vlaskovska, 1999, Biotransformation of nociceptin/orphanin FQ by enzyme activity from morphine-naive and morphine-treated cell cultures, Brain Res., 818, 212, 10.1016/S0006-8993(98)01266-9 Silberring, 1997, Analysis of neuropeptides by size-exclusion HPLC linked to electrospray mass spectrometry, 129 Nylander, 1995, Processing of prodynorphin-derived peptides in striatal extracts, Identification by electrospray-ionization mass spectrometry linked to size-exclusion chromatography. Life Sci., 57, 123 Smoluch, 1999, Size-exclusion chromatography performed in capillaries; Studies by LC/MS, J. Chromatogr. B, 726, 37, 10.1016/S0378-4347(99)00032-8 Hjertén, 1987, A high-performance liquid chromatographic matrix based on agarose cross-linked with divinyl sulphone, J. Chromatogr., 396, 101, 10.1016/S0021-9673(01)94046-4 Sandin, 1999, In vivo and in vitro metabolism of nociceptin/orphanin FQ in the rat hippocampus, Neuroreport, 10, 71, 10.1097/00001756-199901180-00014 Reinscheid, 1995, Orphanin FQ: a neuropeptide that activates an opioid-like G protein-coupled receptor, Science, 270, 792, 10.1126/science.270.5237.792 Meunier, 1995, Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor, Nature, 377, 532, 10.1038/377532a0 Silberring, 1997, Rapid analysis of endogenous LVV-hemorphin-7 in cerebrospinal fluid by size-exclusion chromatography and electrospray ionization mass spectrometry, J. Chromatogr. A, 777, 41, 10.1016/S0021-9673(97)00277-X