Determination of methotrexate and indomethacin in urine using SPE-LC-DAD after derivatization

Balis, 2002, General principles of chemotherapy, 237 Weinblatt, 1995, Methotrexate for chronic diseases in adults, N. Engl. J. Med., 332, 330, 10.1056/NEJM199502023320512 Wang, 2005, Indomethacin suppresses growth of colon cancer via inhibition of angiogenesis in vivo, World J. Gastroenterol., 11, 340, 10.3748/wjg.v11.i3.340 Bennett, 1987, Studies on the mechanism by which indomethacin increases the anticancer effect of methotrexate, Br. J. Pharmacol., 91, 229, 10.1111/j.1476-5381.1987.tb09003.x Kobayashi, 1999, The marked anticancer effect of combined VCR, MTX, and indomethacin against drug-resistant recurrent small cell lung carcinoma after conventional chemotherapy: report of a case, Surg. Today, 29, 666, 10.1007/BF02482998 Frenia, 1992, Methotrexate and nonsteroidal anti-inflammatory drug interactions, Ann. Pharmacother., 26, 234, 10.1177/106002809202600219 Uwai, 2000, Interaction between methotrexate and nonsteroidal anti-inflammatory drugs in organic anion transporter, Eur. J. Pharmacol., 409, 31, 10.1016/S0014-2999(00)00837-2 Nozaki, 2007, Species difference in the inhibitory effect of nonsteroidal anti-inflammatory drugs on the uptake of methotrexate by human kidney slices, J. Phamacol. Exp. Ther., 322, 1162, 10.1124/jpet.107.121491 Maeda, 2008, Evaluation of the interaction between nonsteroidal anti-inflammatory drugs and methotrexate using human organic anion transporter 3-transfected cells, Eur. J. Pharmacol., 596, 166, 10.1016/j.ejphar.2008.08.023 Shen, 1978, Clinical pharmacokinetics of methotrexate, Clin. Pharmacokinet., 3, 1, 10.2165/00003088-197803010-00001 Davies, 2000, Choosing the right nonsteroidal anti-inflammatory drug for the right patient: a pharmacokinetic approach, Clin. Pharmacokinet., 38, 377, 10.2165/00003088-200038050-00001 Rubino, 2001, Separation methods for methotrexate, its structural analogues and metabolites, J. Chromatogr. B, 764, 217, 10.1016/S0378-4347(01)00402-9 Novakova, 2005, Development and validation of HPLC method for determination of indomethacin and its two degradation products in topical gel, J. Pharm. Biomed. Anal., 37, 899, 10.1016/j.jpba.2004.09.012 Stubbs, 1986, Improved method for the determination of indomethacin in plasma and urine by reversed-phase high-performance liquid chromatography, J. Chromatogr. B: Biomed. Sci. Appl., 383, 432, 10.1016/S0378-4347(00)83491-X Vree, 1993, Determination of indomethacin, its metabolites and their glucuronides in human plasma and urine by means of direct gradient high-performance liquid chromatographic analysis: preliminary pharmacokinetics and effect of probenecid, J. Chromatogr. B: Biomed. Sci. Appl., 616, 271, 10.1016/0378-4347(93)80395-K Niopas, 1994, Determination of indomethacin and mefenamic acid in plasma by high-performance liquid chromatography, J. Chromatogr. B: Biomed. Sci. Appl., 656, 447, 10.1016/0378-4347(94)00116-2 2008 2009 Prey, 2009, Effect of folic or folinic acid supplementation on methotrexate-associated safety and efficacy in inflammatory disease: a systematic review, Br. J. Dermatol., 160, 622, 10.1111/j.1365-2133.2008.08876.x Bressole, 1996, Validation of liquid chromatographic and gas chromatographic methods. Applications to pharmacokinetics, J. Chromatogr. B, 686, 3, 10.1016/S0378-4347(96)00088-6 2005 2004, 1133 Miwa, 2000, High-performance liquid chromatographic determination of mono-, poly- and hydroxycarboxylic acids in foods and beverages as their 2-nitrophenylhydrazides, J. Chromatogr. A, 881, 365, 10.1016/S0021-9673(00)00284-3 Miwa, 1985, High-performance liquid chromatography of short-and long-chain fatty acids as 2-nitrophenylhydrazides, J. Chromatogr. A, 321, 165, 10.1016/S0021-9673(01)90433-9 2001 Shah, 2000, Bioanalytical method validation – a revisit with a decade of progress, Pharmaceut. Res., 17, 1551, 10.1023/A:1007669411738 1992 Duggan, 1972, The metabolism of indomethacin in man, J. Pharmacol. Exp. Ther., 181, 563 Jacobs, 1976, 7-Hydroxymethotrexate as a urinary metabolite in human subjects and rhesus monkeys receiving high dose methotrexate, J. Clin. Investig., 57, 534, 10.1172/JCI108308