Design, synthesis and biological evaluation of tyrosinase-targeting PROTACs

European Journal of Medicinal Chemistry - Tập 226 - Trang 113850 - 2021
Dingqiang Fu1,2, Yi Yuan1, Fengming Qin3, Yan Xu1, Xin Cui1, Guangxun Li1, Shaohua Yao3, Yun Deng4, Zhuo Tang1
1Natural Products Research Center, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China
2University of Chinese Academy of Sciences, Beijing, 100049, China
3Laboratory of Biotherapy, National Key Laboratory of Biotherapy, Cancer Center, West China Hospital, Sichuan University, Chengdu, 610041, China
4State Key Laboratory of Southwestern Chinese Medicine Resources, The Ministry of Education Key Laboratory of Standardization of Chinese Herbal Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China

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