Design of synthetic peptides for oral vaccination

La Granderie, 1993, Oral immunization with recombinant BCG induces cellular and humoral immune responses against the foreign antigen, Vaccine, 11, 1283, 10.1016/0264-410X(93)90096-G Dougan, 1987, Live oral Salmonella vaccines: Potential use of attenuated strains as carriers of heterologous antigens to the immune system, Parasite Immunol., 9, 151, 10.1111/j.1365-3024.1987.tb00496.x Langedijk, 1992, Comparison and fine mapping of both high and low neutralizing monoclonal antibodies against the principal neutralization domain of HIV-1, Arch. Virol., 126, 129, 10.1007/BF01309690 Meloen, 1991, The use of peptides to reconstruct conformational determinants. A brief review, Ann. Biol. Clin., 49, 231 Meloen, 1995, PEPSCAN to determine T- and B-cell epitopes Langeveld, 1994, First peptide vaccine providing protection against viral infection in the target animal: Studies of canine parvovirus in dogs, J. Virol., 68, 4506, 10.1128/JVI.68.7.4506-4513.1994 Langeveld, 1994, Effective induction of neutralizing antibodies with the amino terminus of VP2 of canine parvovirus as a synthetic peptide, Vaccine, 12, 1473, 10.1016/0264-410X(94)90158-9 Lenstra, 1992, Isolation of sequences from a random-sequence expression library that mimic viral epitopes, J. Immunol. Methods, 152, 149, 10.1016/0022-1759(92)90136-H Devlin, 1990, Random peptide libraries: a source of specific protein binding molecules, Science, 249, 404, 10.1126/science.2143033 Scott, 1990, Searching for peptide ligands with an epitope library, Science, 249, 386, 10.1126/science.1696028 Cwirla, 1990, Peptides on phage: a vast library of peptides for identifying ligands, 87, 6378 Houghten, 1991, Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery, Nature, 354, 84, 10.1038/354084a0 Fodor, 1991, Light-directed, spatially addressable parallel chemical synthesis, Science, 251, 767, 10.1126/science.1990438 Barbas, 1992, Semisynthetic combinatorial antibody libraries: A chemical solution to the diversity problem, 89, 4457 Geysen, 1984, Use of peptide synthesis to probe viral antigens for epitopes to a resolution of a single amino acid, 81, 3998 Geysen, 1985, Small peptides induce antibodies with a sequence and structural requirements for binding antigen comparable to antibodies raised against the native protein, 82, 178 Meloen, 1986, Epitope mapping of the outer structural protein VP1 of three different serotypes of FMDV, Virology, 149, 55, 10.1016/0042-6822(86)90086-3 Meloen, 1986, The use of peptides to locate epitopes on the surface of Foot-and-Mouth Disease, 34, 103 Meloen, 1987, Antigenicity and immunogenicity of synthetic peptides of foot-and-mouth disease virus, J. Gen. Virol., 68, 305, 10.1099/0022-1317-68-2-305 Posthumus, 1991, Surface locations of foot-and-mouth disease virus type A10 epitopes of neutralizing monoclonal antibodies, 21 McCahon, 1989, Evidence for at least four antigenic sites on type 0 foot-and-mouth disease virus involved in neutralisation; identification by single and multiple site monoclonal antibody resistant mutants, J. Gen. Virol., 70, 639, 10.1099/0022-1317-70-3-639 Brown, 1992, Localization of an immunodominant domain on baculovirus-produced parvovirus B19 capsids: Correlation to a major surface region on the native virus particle, J. Virol., 66, 6989, 10.1128/JVI.66.12.6989-6996.1992 Langeveld, 1993, B-cell epitopes of canine parvovirus: Distribution on the primary structure and exposure on the viral surface, J. Virol., 67, 765, 10.1128/JVI.67.2.765-772.1993 Middeldorp, 1988, Epitope-mapping on the Epstein-Barr virus major capsid protein using systematic synthesis of overlapping oligopeptides, J. Virol. Methods, 21, 147, 10.1016/0166-0934(88)90061-4 Jacobs, 1990, Epitope analysis of glycoprotein I of Pseudorabies virus, J. Gen. Virol., 71, 881, 10.1099/0022-1317-71-4-881 Goudsmit, 1988, HIV type 1 neutralization epitope with conserved architecture elicits early type-specific antibodies in experimentally infected chimpanzees, 85, 4478 Goudsmit, 1988, Baculovirus expressed gp160 of HIV-1 induces antibodies with isolate-specific binding to a nine-amino acid sequence related to type-specific cell fusion inhibition, AIDS, 2, 231 Krone, 1988, Natural antibodies to HIV-tat epitopes and expression of HIV-1 genes in vivo, J. Med. Virol., 26, 261, 10.1002/jmv.1890260306 Goudsmit, 1989, Shared and cross reactive epitopes on peptide antigens binding HIV-1 neutralizing antibodies of susceptible hosts, 145 Goudsmil, 1989, Specificity of chimpanzee antibodies binding a strain specific HIV-1 neutralization epitope of the external envelope, J. Med. Primatol., 18, 357, 10.1111/j.1600-0684.1989.tb00238.x Goudsmit, 1989, Human B-cell epitopes of HIV-2 transmembrane protein are similarly spaced as in HIV-1, J. AIDS, 2, 297 Meloen, 1989, Specificity and function of the individual amino acids of a major determinant of HIV-1 that induces neutralization activity, J. Gen. Virol., 70, 1505, 10.1099/0022-1317-70-6-1505 Boucher, 1990, Immune response and epitope mapping of a candidate HIV-1 p17 vaccine HGP30, J. Clin. Lab. Anal., 4, 43, 10.1002/jcla.1860040109 Brake, 1990, Characterization of murine monoclonal antibodies to the tat protein from human immunodeficiency virus type 1, J. Virol., 64, 962, 10.1128/JVI.64.2.962-965.1990 Goudsmit, 1990, Map of sequential B-cell epilopes of the HIV-1 transmembrane protein using human antibodies as probe, Intervirology, 31, 327, 10.1159/000150169 Langedijk, 1990, Location of epitopes on the major core protein p24 of the human immunodeficiency virus (HIV), J. Gen. Virol., 71, 2609, 10.1099/0022-1317-71-11-2609 Langcdijk, 1991, Neutralizing activity of anti-peptide antibodies against the principal neutralization domain of HIV-1, J. Gen. Virol., 72, 2519, 10.1099/0022-1317-72-10-2519 De Wolf, 1991, Characterization of human antibody binding sites on the external envelope of human immunodeficiency virus type 2, J. Gen. Virol., 72, 1261, 10.1099/0022-1317-72-6-1261 Zwart, 1991, Immunodominance and Antigenic Variation of the Principal Neutralization Domain of HIV-1, Virology, 181, 481, 10.1016/0042-6822(91)90880-K Javaherian, 1992, The principal neutralization determinant of simian immunodeficiency virus differs from that of human immunodeficiency virus type 1, 89, 1418 Langedijk, 1992, Comparison and fine mapping of both high and low neutralizing monoclonal antibodies against the principal neutralization domain of HIV-1, Arch. Virol., 126, 129, 10.1007/BF01309690 Langedijk, 1992, Identification of cross-reactive epitopes recognized by HIV-1 false-positive sera, AIDS, 6, 1547, 10.1097/00002030-199212000-00023 D'Souza, 1991, Evaluation of monoclonal antibodies to HIV-1 by neutralization and serological assays: an international collaboration, AIDS, 5, 1061, 10.1097/00002030-199109000-00001 Kusters, 1989, Analysis of an immunodominant region of avian coronavirus IBV, J. Immunol., 143, 2692, 10.4049/jimmunol.143.8.2692 Luytjes, 1989, Amino acid sequence of a conserved neutralizing epitopc of murine coronaviruses, J. Virol., 63, 1408, 10.1128/JVI.63.3.1408-1412.1989 Bredenbeek, 1990, The polymerase gene of coronaand toroviruses: evidence for an evolutionary relationship, 276, 307 Enjuanes, 1990, Location of antigenic sites of the S-glycoprotein of transmissible gastroenteritis virus and their conservation in coronaviruses, 276, 159 Posthumus, 1990, Analysis and simulation of a neutralizing epitope of transmissible gastroenteritis virus, J. Virol., 64, 3304, 10.1128/JVI.64.7.3304-3309.1990 Posthumus, 1990, Linear neutralizing epitopes on the peplomer protein of coronaviruses, 276, 181 Gebauer, 1991, Residues involved in the antigenic sites of transmissible gastroenteritis coronavirus S glycoprotein, Virology, 183, 225, 10.1016/0042-6822(91)90135-X Versteeg-van Oosten, 1989, Epitope Mapping of the fusion protein of measles virus, 521 Coursaget, 1991, Mapping of linear B-cell epitopes of hepatitis B surface antigen, Virology, 142, 461, 10.1016/0923-2516(91)90068-E Snijders, 1991, Identification of linear epitopes on Semliki Forest virus E2 membrane protein and their effectiveness as a synthetic peptide vaccine, J. Gen. Virol., 72, 557, 10.1099/0022-1317-72-3-557 Chassot, 1993, Fine mapping of neutralization epitopes on duck hepatitis B virus (DHBV) pre-S protein using monoclonal antibodies and overlapping peptides, Virology, 192, 217, 10.1006/viro.1993.1024 Gonzalez, 1993, Immunological characterization of a rotavirus-neutralizing epitope fused to the cholera toxin B subunit, Gene, 133, 227, 10.1016/0378-1119(93)90643-H Radford, 1990, Epitope mapping of the Mycobacterium bovis secretory protein MPB70 using overlapping peptide analysis, J. Gen. Microbiol., 136, 265, 10.1099/00221287-136-2-265 Van Amerongen, 1989, Identification of a peptide sequence of the 25 kD surface protein of Plasmodium falciparum recognized by transmission-blocking monoclonal antibodies: implications for synthetic vaccine development, Parasite Immunol., 11, 425, 10.1111/j.1365-3024.1989.tb00679.x Van Amerongen, 1990, PEPSCAN based amino acid modifications of a P. Falciparum pfs25 peptide sequence substantially increase reactivity with transmission blocking monoclonal antibodies, 461 Stüber, 1990, New B-cell epitopes in the Plasmodium falciparum malaria circumsporozoite protein, Eur. J. Immunol., 20, 819, 10.1002/eji.1830200416 Van Amerongen, 1992, Peptides reactive with a transmission blocking monoclonal antibody against Plasmodium falciparum Pfs25: 2000-fold affinity increase by PEPSCAN-based amino acid substitutions, Peptide Res., 5, 269 Clarke, 1990, Pepscan and circular-dishroism analysis of a repetitive antigen of Trypanosoma cruzi, Biochem. Soc. Trans., 18, 868, 10.1042/bst0180868 Ahlborg, 1991, Definition of the epitope recognized by the Plasmodium falciparum-reactive human monoclonal antibody 33G2, Mol. Biochem. Parasitol., 46, 89, 10.1016/0166-6851(91)90202-H Miles, 1989, Multiple peptide synthesis (Pepscan method) for the systematic analysis of B- and T-cell epitopes: application to parasite proteins, Parasitol. Today, 5, 397, 10.1016/0169-4758(89)90307-4 Grootenhuis, 1989, Inhibin and activin-like activity in fluids from male and female gonads: different molecular weight forms and bioactivity/immunoactivity ratios, J. Endocrinol., 122, 293, 10.1677/joe.0.1220293 Van Amerongen, 1994, Design of peptides with improved affinities for anti-human chononic gonadotropin monoclonal antibodies, Peplide Res., 7, 83 Van 't Hof, 1991, Epitope mapping of the Dermatophagoides pteronyssinus house dust mite major allergen Der p II using overlapping synthetic peptides, Mol. Immunol., 28, 1225, 10.1016/0161-5890(91)90009-9 Van Millegen, 1994, IgE epitopes on the cat (Felis domesticus) major allergen Fei d I: a study with overlapping synthetic peptides, J. Allergy Clin. Immunol., 93, 34, 10.1016/0091-6749(94)90230-5 Tzartos, 1990, Fine localization of the major alpha-bungarotoxin binding site to residues alpha 189–195 of the Torpedo acetylcholine receptor. Residues 189, 190 and 195 are indispensable for binding, J. Biol. Chem., 265, 21462, 10.1016/S0021-9258(18)45760-2 Xing, 1991, Effect of variations in peptide sequence on anti-human milk fat globule membrane antibody reactions, Immunology, 72, 304 Stiemer, 1992, Immunological characterization of an immunomodulatory epitope in S-antigen/arrestin with a sequence motif common to tumor necrosis factor alpha, Immunol. Lett., 32, 233, 10.1016/0165-2478(92)90055-S Germain, 1994, MHC-dependent antigen processing and peptide presentation: providing ligands for T lymphocyte activation, Cell, 76, 287, 10.1016/0092-8674(94)90336-0 Van Lierop, 1994, T-cell stimulatory fragments of foot-and-mouth disease virus released by mild treatment with cathepsin D, J. Gen. Virol., 75, 2937, 10.1099/0022-1317-75-11-2937 Van Lierop, 1995, Sequences derived from the highly antigenic VP1 region 140–160 of Foot-and-mouth disease virus do not prime for a Bovine T-cell response against intact virus, J. Virol., 69, 2782, 10.1128/JVI.69.7.4511-4514.1995 Van der Zee, 1989, Efficient mapping and characterization of a T-cell epitope by the simultaneous synthesis of multiple peptides, Eur. J. Immunol., 19, 43, 10.1002/eji.1830190108 Halimi, 1993, Immune response related to the molecular structure of a peptide from the cholera toxin β subunit, Vaccine, 11, 1233, 10.1016/0264-410X(93)90048-3 Calvo-Calle, 1993, Immunogenicity of multiple antigen peptides containing B and non-repeat T cell epitopes of the circumsporozoite protein of Plasmodium falciparum, J. Immunol., 150, 1403, 10.4049/jimmunol.150.4.1403 Hermanek, 1994, Lymphocyte, antibody and cytokine responses during concurrent infections between helminths that selectively promote T-helper-1 or T-helper-2 activity, Parasite Immunol., 16, 111, 10.1111/j.1365-3024.1994.tb00330.x Ramsay, 1993, Interleukin-5 expressed by a recombinant virus vector enhances specific mucosal IgA responses in vivo, Eur. J. Immunol., 23, 3141, 10.1002/eji.1830231215 Bomford, 1992, The control of the antibody isotype response to recombinant human immunodeficiency virus gpl20 antigen by adjuvants, AIDS Res. Hum. Retroviruses, 8, 1765, 10.1089/aid.1992.8.1765 Sheh, 1993, Studies of the synthesis, immunology, and cytotoxicity of a cyclic octapeptide corresponding to TNF-alpha-(59–66), J. Med. Chem., 36, 4302, 10.1021/jm00078a020 Jones, 1994, Synthetic macrophage activating peptides derived from the N-terminus of human MCF, Biochem. Biophys. Res. Commun., 199, 20, 10.1006/bbrc.1994.1186 Husband, 1993, Novel vaccination strategies for the control of mucosal infection, Vaccine, 11, 107, 10.1016/0264-410X(93)90003-G Burroughs, 1993, A structure-activity relationship for induction of meningeal inflammation by muramyl peptides, J. Clin. Invest., 92, 297, 10.1172/JCI116565 Tagliabue, 1993, Cytokines as vaccine adjuvants: interleukin 1 and its synthetic peptide 163–171, Vaccine, 11, 594, 10.1016/0264-410X(93)90240-X Orlandi, 1993, Orientation of cholera toxin hound to target cells, J. Biol. Chem., 268, 17038, 10.1016/S0021-9258(19)85298-5 Dertzbauch, 1993, Comparative effectiveness of the cholera toxin B subunit and alkaline phosphatase as carriers for oral vaccines, Infect. Immun., 61, 48, 10.1128/IAI.61.1.48-55.1993 Morris, 1994, Potential of polymer microencapsulation technology for vaccine innovation, Vaccine, 12, 5, 10.1016/0264-410X(94)90003-5