Design and conduct of clinical trials in patients with osteoarthritis: Recommendations from a task force of the Osteoarthritis Research Society

Osteoarthritis and Cartilage - Tập 4 Số 4 - Trang 217-243 - 1996
Roy D. Altman1, Kenneth D. Brandt2, Marc C. Hochberg3, Roland W. Moskowitz4, Nicholas Bellamy, D. Blöch5, Joseph A. Buckwalter6, M Dougados7, George E. Ehrlich8, Michel Lequesne7, Stefan Lohmander9, William A. Murphy10, Theresa Rosario-Jansen11, Benjamin J. Schwartz12, Stephen B. Trippel13
1Miami Dept. Veterans Affairs Hosp., FL 33125, USA.
2Indianapolis, IN, U.S.A.
3Baltimore, Md., U.S.A.
4Cleveland, OH, U.S.A.
5Stanford, CA, U.S.A.
6Iowa City, IO, U.S.A.
7Paris – France
8Philadelphia, PA, U.S.A.
9Lund, Sweden
10Houston, TX, U.S.A.
11Cincinnati, OH, U.S.A.
12St. Louis, Mo. U.S.A.
13Boston, MA, U.S.A.

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Lequesne, 1994, Guidelines for testing slow acting drugs in osteoarthritis, J Rheumatol, 21, 65

1995

Furst, 1995

1996, Recommendations for the registration of drugs used in the treatment of osteoarthritis, Ann Rheum Dis, 55, 552, 10.1136/ard.55.8.552

Bellamy, 1996, Recommendations for a core set of outcome measures for future phase III clinical trials in knee, hip, and hand osteoarthritis: consensus development at OMERACT III, J Rheumatol

Altman, 1983, Degenerative joint disease, Clin Rheum Dis, 9, 681, 10.1016/S0307-742X(21)00653-6

Rataiu, 1990, Clinical trials: a guide to understanding methodology and interpreting results, Arthritis Rheum, 33, 131, 10.1002/art.1780330118

FDA Document #77-3040. General considerations for the clinical evaluation of drugs, CDER Executive secretarial staff, HFD-8, FDA (Center for Drug Evaluation and Research, 5400 Fisher's lane, Rockville, MD 20857.

FDA Document: Guidelines for industry. The extent of population exposure to assess clinical safety: for drugs intended for long-term treatment of non-lifethreatening conditions, ICH-EIA, March 1995; Federal Register March 1, 1995 (60FR11270).

Altman, 1986, Development of criteria for the classification and reporting of osteoarthritis: classification of osteoarthritis of the Knee, Arthritis Rheum, 29, 1039, 10.1002/art.1780290816

ACR Subcommittee on Classification Criteria of Osteoarthritis—Altman RD, 1990, Chairman: The American College of Rheumatology Criteria for the Classification and Reporting of Osteoarthritis of the Hand, Arthritis Rheum, 33, 1601, 10.1002/art.1780331101

ACR Subcommittee on Classification Criteria of Osteoarthritis—Altman RD, 1991, Chairman: The American College of Rheumatology Criteria for the Classification and Reporting of Osteoarthritis of the Hip, Arthritis Rheum, 34, 505, 10.1002/art.1780340502

Kellgren, 1957, Radiological assessment of osteoarthritis, Ann Rheum Dis, 16, 494, 10.1136/ard.16.4.494

Kellgren, 1963, The epidemiology of chronic rheumatism. Atlas of standard radiographs of arthritis, 1

Burnett, 1994

Kalman, 1989, New radiographic grading scales of osteoarthritis of the hand, Arthritis Rheum, 32, 1584, 10.1002/anr.1780321213

Altman, 1995, Atlas of individual radiographic features in osteoarthritis, Osteoarthritis Cart, 3, 3

Spector, 1994, Indicence and progression of osteoarthritis in women with unilateral knee disease in the general population: the effect of obesity, Ann Rheum Dis, 53, 565, 10.1136/ard.53.9.565

Neyret, 1993, Partial meniscectomy and anterior cruciate ligament rupture in soccer players: a study with a minimum 20-yr follow-up, Am J Sports Med, 21, 455, 10.1177/036354659302100322

Roos, 1994, The prevalence of gonarthrosis and its relation to meniscectomy in former soccer players, Am J Sports Med., 22, 219, 10.1177/036354659402200211

Croft, 1990, Defining osteoarthritis of the hip for epidemiologic studies, Am J Epidemiol, 132, 514, 10.1093/oxfordjournals.aje.a115687

Hochberg, 1995, The association of radiographic changes of osteoarthritis of the hand and hip in elderly women, J Rheumatol, 22, 2291

Sharif, 1995, Serum hyaluronic acid level as a predictor of disease progression in osteoarthritis of the knee, Arthritis Rheum, 38, 760, 10.1002/art.1780380608

Sharif, 1995, Relationship between serum cartilage oligomeric matrix protein levels and disease progression in osteoarthritis of the knee joint, Br J Rheumatol, 34, 306, 10.1093/rheumatology/34.4.306

Bellamy, 1988, Validation of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee, J Rheumatol, 15, 1833

Lequesne, 1987, Indices of severity for osteoarthritis of the hip and knee, Scand J Rheumatol, 85, 10.3109/03009748709102182

U.S. Food and Drug Administration Regulations 21 CFR Parts 50.20–50.27.

Haynes, 1987, Patient compliance and the conduct and interpretation of therapeutic trials, Controlled Clin Trials, 8, 12, 10.1016/0197-2456(87)90021-3

Drummond, 1980

Ehrlich, 1996, Treatment decisions, side-effect liability and cost-effectiveness in osteoarthritis, Inflammopharmacology, 4, 137, 10.1007/BF02735468

Fries, 1980, Measurement of patient outcome in arthritis, Arthritis Rheum, 23, 137, 10.1002/art.1780230202

Meenan, 1980, Measuring health status in arthritis: the Arthritis Impact Measurement Scales, Arthritis Rheum, 23, 146, 10.1002/art.1780230203

Mason, 1989, Application of a health status model to osteoarthritis, Arthritis Care Res, 2, 89, 10.1002/anr.1790020303

Treves, 1994, Therapeutic trials in digital osteoarthritis. A critical review, Revue Rheumatisme Engl edition, 626, 33S

Bellamy, 1996, Development of a disease-specific health status measure for hand osteoarthritis clinical trials. 1. Assessment of the symptom dimensionality, Scand J Rheumatol, 5

Ware, 1992, The MOS 36-item short-form health survey (SF36): I. Conceptual framework and item selection, Med Care, 30, 473, 10.1097/00005650-199206000-00002

Bergner, 1981, The Sickness Impact Profile: development and final revision of a health status measure, Med Care, 19, 778, 10.1097/00005650-198108000-00001

Hunt, 1980, The development of a subjective health indicator, Sociol Health Illness, 2, 231, 10.1111/1467-9566.ep11340686

1990, Euroqol: A new facility for the measurement of health related quality of life, Health Policy, 16, 199, 10.1016/0168-8510(90)90421-9

Torrance, 1976, Social preferences for health status. An empirical evaluation of the measurement techniques, Socio-economic Planning Sciences, 10, 128, 10.1016/0038-0121(76)90036-7

Feeny, 1992, A comprehensive multiattribute system for classifying the health status of survivors of childhood cancer, J Clin Oncol, 10, 923, 10.1200/JCO.1992.10.6.923

Theiler, 1994, Parametric and non-parametric measures in the assessment of knee and hip osteoarthritis: interobserver reliability and correlation with radiology, Osteoarthritis Cart, 2, 1, 10.1016/S1063-4584(05)80002-0

Rejeski, 1995, Assessing performance related disability in patients with knee osteoarthritis, Osteoarthritis Cart, 3, 157, 10.1016/S1063-4584(05)80050-0

Felson, 1995, American College of Rheumatology Preliminary definition of improvement in rheumatoid arthritis, Arthritis Rheum, 38, 727, 10.1002/art.1780380602

Hochberg, 1996, Quantitative radiography: osteoarthritis-analysis, Bailliere's Clin Rheum, 10

Dougados, 1995, Sensitivity to change of various roentgenological severity scoring systems for osteoarthritis of the hip, Rev Rhum, 62, 169

Lequesne, 1995, Chondrometry quantitative evaluation of joint space width and rate of joint space loss in osteoarthritis of the hip, Rev Rhum, 62, 155

Buckland-Wright, 1995, Accuracy and precesion of joint space width measurements in standard and macroradiographs of osteoarthritic knees, Ann Rheum Dis, 54, 872, 10.1136/ard.54.11.872

Ravaud, 1996, Radiographic assessment of knee osteoarthritis: reproducibility and sensitivity to change, J Rheumatol, 23, 1756

Dieppe, 1995, Standardization of methods used to assess the progression of osteoarthritis of hip and knee, 481

Buckland-Wright, 1995, Protocols for precise radio-anatomical positioning of the tibiofemoral and patellofemoral compartments of the knee, Osteoarthritis Cart, 3, 71

Ravaud, 1996, An experimental study of the influence of radiographic procedure and joint positioning on knee joint space width measurement, Br J Rheumatol, 35, 761, 10.1093/rheumatology/35.8.761

Mazzuca S, Brandt KD, Katz B. Is conventional radiography suitable for evaluation of a diseasemodifying drug in patients with knee osteoarthritis. Osteoarthritis Cart. In press.

Buckland-Wright, 1995, Radioanatomic assessment of therapeutic outcome in osteoarthritis, 51

Klashman, 1995, Validation of an osteoarthritis data report form for knee arthroscopy, Arthritis Rheum, 38, S178

Ayral, 1996, Arthroscopic evaluation of chondropathy in osteoarthritis of the knee, J Rheumatol, 23, 698

Poole, 1994, Immunochemical markers of joint inflammation, skeletal damage and repair; where are we now?, Ann Rheum Dis, 53, 3, 10.1136/ard.53.1.3

Lohmander, 1994, Articular cartilage and osteoarthrosis—the role of molecular markers to monitor breakdown, repair and disease, J Anat, 184, 477

Lark, 1995, Aggrecan degradation in osteoarthritis and rheumatoid arthritis, Acta Orthop Scand, 66, 92, 10.3109/17453679509157660

Hully, 1988

Meinert, 1986

Bellamy, 1996, Recommendations for a core set of outcome measures for future phase III clinical trials in knee, hip and hand osteoarthritis. Consensus development at OMERACT III, J Rheumatol

Bellamy, 1993, Pain measurement, 65

Bellamy, 1982, Osteoarthritis—An evaluative index for clinical trials

Bellamy, 1988, Validation study of WOMAC: a health status instrument for measuring clinically important patient-relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee, J Rheumatol, 15, 1833

Bellamy, 1988, Validation study of WOMAC: a health status instrument for measuring clinically-important patient-relevant outcomes following total hip or knee arthroplasty in osteoarthritis, J Orthopaed Rheumatol, 1, 95

Bellamy, 1996

Lequesne, 1987, Indexes of severity for osteoarthritis of the hip and knee: validation-value in comparison with other assessment tests, Scandinavian J Rheumatol, 85, 10.3109/03009748709102182

Lequesne, 1991, Indices of severity and disease activity for osteoarthritis, Semin Arthritis Rheum, 20, 48, 10.1016/0049-0172(91)90027-W

Fries, 1980, Measurement of patient outcome in arthritis, Arthritis Rheum, 23, 137, 10.1002/art.1780230202

Meenan, 1980, Measuring health status in arthritis: the Arthritis Impact Measurement Scales, Arthritis Rheum, 23, 146, 10.1002/art.1780230203

Meenan, 1992, AIMS2. The content and properties of a revised and expanded Arthritis Impact Measurement Scales Health Status Questionnaire, Arthritis Rheum, 35, 1, 10.1002/art.1780350102

Bellamy, 1996, Development of a disease-specific health status measure for hand osteoarthritis clinical trials. I. Assessment of symptom dimensionality [Abstract], Scand J Rheumatol, 5

Bellamy, 1993, Health status instruments and functional indices. Musculoskeletal Clinical Metrology, 77

Dreiser, 1995, Validation of an algofunctional index for osteoarthritis of the hand, Revue du rhumatisme, 43S

Bellamy, 1993, Standardized procedures for outcome measurement and parameters for calculating sample size for antirheumatic-drug studies, 193

Ware, 1992, The MOS 36-item Short-Form Health Status Survey (SF-36): I. Conceptual framework and item selection, Medical Care, 30, 473, 10.1097/00005650-199206000-00002

Jobanputra, 1994, Validity of Euroqol—a generic health status instrument in patients with rheumatoid arthritis, Br J Rheumatol, 33, 655, 10.1093/rheumatology/33.7.655

1992

Feeny, 1992, A comprehensive multiattribute system for classifying the health status of survivors of childhood cancer, J Clin Oncol, 10, 923, 10.1200/JCO.1992.10.6.923

Von Neumann, 1953

Torrance, 1972, A utility maximization model for evaluation of health care programs, Health Services Research, 7, 118

Torrance, 1976, Social preferences for health states: an empirical evaluation of three measurement techniques, Socioeconomic Planning Sciences, 10, 128, 10.1016/0038-0121(76)90036-7

Bellamy, 1993, Mechanical and electromechanical devices, 117

Lequesne, 1995, Quantitative measurement of joint space during progression of osteoarthritis: ‘chondrometry’, 427

Conrozier, 1995, Quantitative assessment of radiographic normal and osteoarthritic hip joint space, Osteoarthritis Cart, 3, 81

Buckland-Wright, 1997, Quantitation of radiographic change

Fife, 1991, Relationship between arthroscopic evidence of cartilage damage and radiographic evidence of joint space narrowing in early osteoarthritis of the knee, Arthritis Rheum, 34, 377, 10.1002/art.1780340402

Lynch, 1993, Precision of joint space width measurement in knee ostcoanhritis from digital image analysis of high definition macroradiographs, Osteoarthritis Cart, 1, 209, 10.1016/S1063-4584(05)80327-9

Dieppe, 1995, Recommended methodology for assessing the progression of osteoarthritis of the hip and knee joint, Osteoarthritis Cart, 3, 73, 10.1016/S1063-4584(05)80040-8

Ravaud, 1996, Knee joint space width measurement: an experimental study of the influence of radiographic procedure and joint positioning, Br J Rheumatol, 35, 761, 10.1093/rheumatology/35.8.761

Ravaud, 1996, Radiographic assessment of knee osteoarthritis: reproducibility and sensitivity to change, J Rheumatol, 23, 1756

Ravaud, 1996, Assessment of joint space width in patients with osteoarthritis of the knee: a comparison of four measuring instruments, J Rheumatol, 23, 1

Buckland-Wright, 1995, Protocols for precise radio-anatomical position of the tibiofemoral and patellofemoral compartment of the knee, Osteoarthritis Cart, 3, 71

Buckland-Wright, 1995, Accuracy and precision of joint space width measurement in standard and macroradiographs of osteoarthritic knees, Ann Rheum Dis, 54, 872, 10.1136/ard.54.11.872

Mazzuca S, Brandt KD, Katz B. Is conventional radiography suitable for evaluation of a disease-modifying drug in patients with knee osteoarthritis. Osteoarthritis Cart. In press.

Buckland-Wright, 1995, Joint space width measures cartilage thickness in osteoarthritis of the knee: high resolution plain film and double contrast macroradiographic investigation, Ann Rheum Dis, 54, 263, 10.1136/ard.54.4.263

Thomas, 1975, Compartmental evaluation of osteoarthritis of the knee. A comparative study of available diagnostic modalities, Radiology, 116, 585, 10.1148/116.3.585

Lequesne, 1994, Guidelines for testing slow acting drugs in OA, 21, 65

Peterfy, 1996, Emerging applications of magnetic resonance imaging for evaluating the articular cartilage, Radiol Clin N Am, 34, 195, 10.1016/S0033-8389(22)00463-8

Peterfy, 1994, MR imaging of the arthritic knee: improved discrimination of cartilage, synovium and effusion with pulsed saturation transfer and fat-suppressed T1-weighted sequences, Radiology, 191, 413, 10.1148/radiology.191.2.8153315

Peterfy, 1994, Quantification of articular cartilage in the knee by pulsed saturation transfer and fat-suppressed MRI: optimization and validation, Radiology, 192, 485, 10.1148/radiology.192.2.8029420

Recht, 1996, Accuracy of fat-suppressed three-dimensional spoiled gradient-echo FLASH MR imaging in the detection of patellofemoral articular cartilage abnormalities, Radiology, 198, 209, 10.1148/radiology.198.1.8539380

Disler, 1996, Fat-suppressed three-dimensional spoiled gradient-echo MR imaging of hyaline cartilage defects in the knee: comparison with standard MR imaging and arthroscopy, AJR, 167, 127, 10.2214/ajr.167.1.8659356

Recht, 1993, Abnormalities of articular cartilage in the knee: analysis of available MR techniques, Radiology, 187, 473, 10.1148/radiology.187.2.8475293

Peterfy, 1995, Quantification of articular cartilage in the metacarpophalangeal joints of the hand: accuracy and precision of 3D MR imaging, AJR, 165, 371, 10.2214/ajr.165.2.7618560

Robson, 1995, A combined analysis and magnetic resonance imaging technique for computerised automatic measurement of cartilage thickness in the distal interphalangeal joint, Magnetic Resonance Imag, 13, 709, 10.1016/0730-725X(95)00025-C

Ateshian, 1995

Selby, 1995, In vivo MR quantification of articular cartilage water content: a potential early indicator of osteoarthritis. Book of Abstracts: Society of Magnetic Resonance 1995, 204

Burstein, 1993, Diffusion of small solutes in cartilage as measured by nuclear magnetic resonance (NMR) spectroscopy and imaging, J Orthop Res, 11, 465, 10.1002/jor.1100110402

Xia, 1994, Diffusion and relaxation mapping of cartilage-bone plugs and excised disks using microscopic magnetic resonance imaging, Magn Reson Med, 31, 273, 10.1002/mrm.1910310306

Kusaka, 1992, MR microimaging of articular cartilage and contrast enhancement by manganese ions, Magn Reson Med, 24, 137, 10.1002/mrm.1910240114

Eng, 1991, Quantitative 1 H magnetization transfer imaging in vivo, Magn Reson Med, 17, 304, 10.1002/mrm.1910170203

Rubenstein, 1993, Effects of collagen Orientation on MR imaging characteristics of bovine cartilage, Radiology, 188, 219, 10.1148/radiology.188.1.8511302

Peterfy, 1996, Applications of magnetic resonance imaging in arthritis

Resnick, 1995, Internal derangements of joints, 3063

Bell, 1996, Economics of MRI technology, JMRI, 6, 10, 10.1002/jmri.1880060105

Peterfy, 1996, Dedicated extremity MRI: an emerging technology

Dieppe, 1995, Standardization of methods used to assess the progression of osteoarthritis of hip and knee, 481