Design and Development of a Clot Burst Pressure Device to Investigate Resuscitation Strategies

Rhee, 2014, Increasing trauma deaths in the United States, Ann Surg, 260, 13, 10.1097/SLA.0000000000000600 Kauvar, 2006, Impact of hemorrhage on trauma outcome: an overview of epidemiology, clinical presentations, and therapeutic considerations, J Trauma Inj Infect Crit Care, 60, S3 Spahn, 2013, Management of bleeding and coagulopathy following major trauma: an updated European guideline, Crit Care, 17, 3, 10.1186/cc12685 Sumislawski, 2018, Dynamic coagulability after injury: is delaying venous thromboembolism chemoprophylaxis worth the wait?, J Trauma Acute Care Surg, 85, 907, 10.1097/TA.0000000000002048 Rezende-Neto, 2010, Permissive hypotension and desmopressin enhance clot formation, J Trauma Inj Infect Crit Care, 68, 42 Smith, 2014, Hypotensive resuscitation, Curr Anesthesiol Rep, 4, 209, 10.1007/s40140-014-0064-7 Bolliger, 2010, Haemodilution-induced profibrinolytic state is mitigated by fresh-frozen plasma: Implications for early haemostatic intervention in massive haemorrhage, Br J Anaesth, 104, 318, 10.1093/bja/aeq001 Morrison, 2011, Hypotensive resuscitation strategy reduces transfusion requirements and severe postoperative coagulopathy in trauma patients with hemorrhagic shock: preliminary results of a randomized controlled trial, J Trauma Inj Infect Crit Care, 70, 652 Owattanapanich, 2018, Risks and benefits of hypotensive resuscitation in patients with traumatic hemorrhagic shock: a meta-analysis, Scand J Trauma Resusc Emerg Med, 26, 1, 10.1186/s13049-018-0572-4 Tapia, 2013, TEG-guided resuscitation is superior to standardized MTP resuscitation in massively transfused penetrating trauma patients, J Trauma Acute Care Surg, 74, 378, 10.1097/TA.0b013e31827e20e0 Dunham, 2014, TEG® and RapidTEG® are unreliable for detecting warfarin-coagulopathy: a prospective cohort study, Thromb J, 12, 1, 10.1186/1477-9560-12-4 George, 2018, A useful device to measure kinetics of platelet contraction, ASAIO J, 64, 529, 10.1097/MAT.0000000000000677 Levy, 2015, How I use fibrinogen replacement therapy in acquired bleeding, Blood, 125, 1387, 10.1182/blood-2014-08-552000 Erdfelder, 2009, Statistical power analyses using G∗Power 3.1: tests for correlation and regression analyses, Behav Res Methods, 41, 1149, 10.3758/BRM.41.4.1149 Machlus, 2011, Causal relationship between hyperfibrinogenemia, thrombosis, and resistance to thrombolysis in mice, Blood, 117, 4953, 10.1182/blood-2010-11-316885 Schöchl, 2009, Hyperfibrinolysis after major trauma: Differential diagnosis of lysis patterns and prognostic value of thrombelastometry, J Trauma, 67, 125 Govindarajan, 2018, Impact of tissue factor Localization on blood clot structure and resistance under venous shear, Biophys J, 114, 978, 10.1016/j.bpj.2017.12.034 Collet, 2005, The elasticity of an individual fibrin fiber in a clot, Proc Natl Acad Sci U S A, 102, 9133, 10.1073/pnas.0504120102 Campbell, 2010, Flow profoundly influences fibrin network structure: Implications for fibrin formation and clot stability in haemostasis, Thromb Haemost, 104, 1281, 10.1160/TH10-07-0442