Desialylation of human cancer cells leading apoptosis by treatment with purified and overexpressed nanI cloned from Clostridium perfringens ATCC 10543

Faillard, 1989, The early history of sialic acids, Trends Biochem Sci, 14, 237, 10.1016/0968-0004(89)90034-0 Yogeeswaran, 1981, Metastatic potential is positively correlated with cell surface sialylation of cultured murine tumor cell lines, Science, 212, 1514, 10.1126/science.7233237 Rapoport, 1999, Glycosylation alterations of cells in late phase apoptosis from colon carcinomas, Glycobiology, 12, 1337, 10.1093/glycob/9.12.1337 Roggentin, 1995, Diversity in the properties of two sialidase isoenzymes produced by Clostridium perfringens spp, Biol Chem Hoppe-Seyler, 376, 569, 10.1515/bchm3.1995.376.9.569 Bouwstra, 1987, Purification and kinetic properties of sialidase from Clostridium perfringens, Biol Chem Hoppe-Seyler, 368, 269, 10.1515/bchm3.1987.368.1.269 Muller, 1974, Neuraminidase of bacteria and protozoa and their pathogenic role, Behring Inst Mitt, 55, 34 Newstead, 2004, Crystallization and atomic resolution X-ray diffraction of the catalytic domain of the large sialidase, nanI, from Clostridium perfringens, Acta Crystallogr D Biol Crystallogr, 60, 2063, 10.1107/S090744490402181X Thobhani, 2003, Multivalency and the mode of action of bacterial sialidases, J Am Chem Soc, 125, 7154, 10.1021/ja029759w Tokuyama, 1997, Suppression of pulmonary metastasis in murine B16 melanoma cells by transfection of a sialidase cDNA, Int J Cancer, 73, 410, 10.1002/(SICI)1097-0215(19971104)73:3<410::AID-IJC16>3.0.CO;2-G Sawada, 2002, Reduced sialidase expression in highly metastatic variants of mouse colon adenocarcinoma 26 and retardation of their metastatic ability by sialidase overexpression, Int J Cancer, 97, 180, 10.1002/ijc.1598 Flores-Diaz, 2005, A cellular deficiency of gangliosides causes hypersensitivity to Clostridium perfringens phospholipase C, J Biol Chem, 280, 26680, 10.1074/jbc.M500278200 Sheu, 2002, Cloning expression, and deletion analysis of large nanI of Clostridium perfringens ATCC 10543, Enzyme Microb Technol, 31, 794, 10.1016/S0141-0229(02)00177-1 Enari, 1995, Involvement of an ICE-like proteases in Fas-mediated apoptosis, Nature, 375, 78, 10.1038/375078a0 Kohler, 2002, Evaluation of caspase activity in apoptotic cells, J Immunol Methods, 265, 97, 10.1016/S0022-1759(02)00073-X Schauer, 1985, Sialic acids and their role as biological masks, TIBS, 10, 357 0rntoft, 1990, O-linked mucin-type glycoproteins in normal and malignant colon mucosa: lack of T-antigen expression and accumulation of Tn and sialosyl-Tn antigens in carcinomas, Int J Cancer, 45, 666, 10.1002/ijc.2910450416 Cao, 1997, Immunodetection of epithelial mucin (MUC1, MUC3) and mucin-associated glycotopes (TF, Tn, and sialosyl-Tn) in benign and malignant lesions of colonic epithelium: apolar localization corresponds to malignant transformation, Virchows Arch, 431, 159, 10.1007/s004280050083 Kato, 2001, Overexpression of lysosomal-type sialidase leads to suppression of metastasis associated with reversion of malignant phenotype in murine B16 melanoma cells, Int J Cancer, 92, 797, 10.1002/ijc.1268 Kakugawa, 2002, Up-regulation of plasma membrane-associated ganglioside sialidase (Neu3) in human colon cancer and its involvement in apoptosis suppression, Proc Natl Acad Sci, 99, 10718, 10.1073/pnas.152597199 Ueno, 2006, Plasma membrane-associated sialidase is up-regulated in renal cell carcinoma and promotes interleukin-6-induced apoptosis suppression and cell motility, J Biol Chem, 281, 7756, 10.1074/jbc.M509668200 Vierbuchen, 1995, Quantitative lectin-histochemical and immunohistochemical studies on the occurrence of alpha(2,3)-and alpha(2,6)-linked sialic acid residues in colorectal carcinomas, Cancer, 76, 727, 10.1002/1097-0142(19950901)76:5<727::AID-CNCR2820760504>3.0.CO;2-R Bosch, 1998, Preparation and characterization of differently aggregated colorectal carcinoma cell subpopulations from surgical specimens, Cancer Detect Prev, 22, 319, 10.1046/j.1525-1500.1998.CDOA42.x Zhu, 2001, Suppression of a sialyltransferase by antisense DNA reduces invasiveness of human colon cancer cells in vitro, Biochem Biophys Acta, 1536, 148 Keppler, 1999, Differential sialylation of cell surface glycoconjugates in a human B lymphoma cell line regulates susceptibility for CD95 (APO-l/Fas)-mediated apoptosis and for infection by a lymphotropic virus, Glycobiology, 9, 557, 10.1093/glycob/9.6.557 Peter, 1995, Cell-surface sialylation plays a role in modulating sensitivity towards APO-1 mediated apoptotic cell-death, Cell Death Differ, 2, 163 Adams, 1998, The Bcl-2 protein family: arbiters of cell survival, Science, 281, 1322, 10.1126/science.281.5381.1322 Ashkenazi, 1998, Death receptors: signaling and modulation, Science, 281, 1305, 10.1126/science.281.5381.1305 Green, 2000, Apoptotic pathways: paper wraps stone blunts scissors, Cell, 102, 1, 10.1016/S0092-8674(00)00003-9 Hengartner, 2000, The biochemistry of apoptosis, Nature, 7, 70 Reed, 2000, Mechanisms of apoptosis, Am J Pathol, 157, 1415, 10.1016/S0002-9440(10)64779-7 Yamaguchi, 2002, Bcl-XL protects BimEL-induced Bax conformational change and cytochrome C release independent of interacting with Bax or BimEL, J Biol Chem, 277, 41604, 10.1074/jbc.M207516200 Cheng, 2001, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis, Mol Cell, 8, 705, 10.1016/S1097-2765(01)00320-3 Kashkar, 2002, Defective Bax activation in Hodgkin B-cell lines confers resistance to staurosporine-induced apoptosis, Cell Death Differ, 9, 750, 10.1038/sj.cdd.4401024 Cheng, 2006, Mitochondrial factors with dual roles in death and survival, Oncogene, 25, 4697, 10.1038/sj.onc.1209596 Wang, 2001, The expanding role of mitochondria in apoptosis, Genes Dev, 15, 2922 Naumovski, 1994, Bcl2 inhibits apoptosis associated with terminal differentiation of HL-60 myeloid leukemia cells, Blood, 83, 2261, 10.1182/blood.V83.8.2261.2261 Li, 2006, Catalpol modulates the expressions of Bcl-2 and Bax and attenuates apoptosis in gerbils after ischemic injury., Brain Res, 115, 179, 10.1016/j.brainres.2006.07.063 Azad N, Vallyathan V, Wang L, Tantishaiyakul V, Stehlik C, Leonard SS, Rojanasakul Y. S-nitrosylation of Bcl-2 inhibits its ubiquitin-proteasomal degradation: a novel anti-apoptotic mechanism that suppresses apoptosis. J Biol Chem 2006;15 [Epub ahead of print].