Dermatofibrosarcoma protuberans: therapeutic challenges
Tóm tắt
Dermatofibrosarcoma protuberans (DFSP) is an uncommon dermal neoplasm with proclivity for recurrence with little metastatic potential. Patients with histologic diagnosis of DFSP seen during a ten year period (January 2000 to December 2009) at the University of Calabar Teaching Hospital Calabar, Nigeria were studied. In total, 11 patients (5 males and 6 females) whose ages ranged from 17–52 years (mean 31.7 years) accounted for 6.8% of skin malignancies. The commonest site was the trunk 6 (54.5%), the head and neck ranked second, 3 (27.3%) followed by the lower limb 2 (18.2%). Eight (73%) patients presented with recurrent lesions. Follow up was poor (mean 6.8 months). DFSP is an uncommon tumour with most patients presenting with recurrent lesions. Follow up was poor; consequently, we advocate adjuvant radiotherapy and treatment with imatinib be included in patients treatment plan from the onset.
Tài liệu tham khảo
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