Derivation of new reference tables for human heart weights in light of increasing body mass index

Journal of Clinical Pathology - Tập 64 Số 4 - Trang 358-362 - 2011
Kezia Gaitskell1, Rafael Perera2, Elizabeth J. Soilleux3
1Somerville College, Oxford University, Oxford, UK
2Department of Primary Health Care, Oxford University, Headington, Oxford, UK
3Consultant Pathologist/Honorary Senior Clinical Lecturer, Department of Cellular Pathology, John Radcliffe Hospital/ Oxford University, Headley Way, Headington, Oxford OX3 9DU, UK

Tóm tắt

As body weights and body mass indices have increased over time, we questioned the validity of correlating heart weight with body weight and whether tables from previous decades remain relevant. We investigated this by collecting details of heart weight, body weight, height, gender and age from 384 autopsy cases with no obvious heart or lung disease. Heart weights, body weights and heights showed a normal distribution for both genders. Heart weight correlated slightly better with body surface area than body weight and we present new reference charts derived from these data. The correlation between heart weight and body weight has changed little, despite increases in body weight and body mass index. As life expectancy is increasing, we investigated the effect of age on heart weight and demonstrated a small increase in heart weight relative to body surface area for both genders, in contrast to a previous study.

Từ khóa


Tài liệu tham khảo

Schoen FJ Mitchell RN . The heart. In: Kumar V Abbas AK Fausto N , eds. The Pathologic Basis of Disease. Philadelphia: Elsevier Saunders, 2010:529–87.

10.1016/j.mpdhp.2008.11.005

10.1016/S0002-8703(29)90099-5

10.1038/ijo.2008.247

Low, 2009, Review on epidemic of obesity, Ann Acad Med Singapore, 38, 57, 10.47102/annals-acadmedsg.V38N1p57

Kuczmarski, 2000, Criteria for definition of overweight in transition: background and recommendations for the United States, Am J Clin Nutr, 72, 1074, 10.1093/ajcn/72.5.1074

10.1016/S0379-0738(00)00401-1

10.1016/S0025-6196(12)64946-5

Cunha, 2002, Heart weight and heart weight/body weight coefficient in malnourished adults, Arq Bras Cardiol, 78, 382, 10.1590/S0066-782X2002000400005

10.1001/archinte.1933.00160060085007

10.1080/15287390802647203

Du Bois, 1989, A formula to estimate the approximate surface area if height and weight be known. 1916, Nutrition, 5, 303

10.1002/sim.4780111005

10.1016/j.mcna.2009.02.010

10.1016/j.jacc.2005.02.075