Depressive symptoms and anti-N-methyl-D-aspartate-receptor GluN1 antibody seropositivity in the PROSpective cohort with incident stroke

Amidfar, 2019, The role of NMDA receptor in neurobiology and treatment of major depressive disorder: evidence from translational research, Prog. Neuro-Psychopharmacol. Biol. Psychiatry, 94, 10.1016/j.pnpbp.2019.109668 Arwert, 2018, Poststroke depression: a long-term problem for stroke survivors, Am. J. Phys. Med. Rehabil., 97, 565, 10.1097/PHM.0000000000000918 Collaborators, 2019, Global, regional, and national burden of neurological disorders, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016, Lancet Neurol., 18, 459, 10.1016/S1474-4422(18)30499-X Daguano Gastaldi, 2023, Factors predisposing to humoral autoimmunity against brain-antigens in health and disease: analysis of 49 autoantibodies in over 7000 subjects, Brain Behav. Immun., 108, 135, 10.1016/j.bbi.2022.10.016 Dahm, 2014, Seroprevalence of autoantibodies against brain antigens in health and disease, Ann. Neurol., 76, 82, 10.1002/ana.24189 Dalmau, 2007, Paraneoplastic anti-N-methyl-D-aspartate receptor encephalitis associated with ovarian teratoma, Ann. Neurol., 61, 25, 10.1002/ana.21050 Dar, 2017, Post stroke depression frequently overlooked, undiagnosed, untreated, Neuropsychiatry, 7, 906 Daza, 2017, Estimating inverse-probability weights for longitudinal data with dropout or truncation: the xtrccipw command, STATA J., 17, 253, 10.1177/1536867X1701700202 Deutsch, 2021, Autoantibodies against the NMDAR subunit NR1 are associated with neuropsychiatric outcome after ischemic stroke, Brain Behav. Immun., 96, 73, 10.1016/j.bbi.2021.05.011 Dhawan, 2011, A new look at glutamate and ischemia: NMDA agonist improves long-term functional outcome in a rat model of stroke, Future Neurol., 6, 823, 10.2217/fnl.11.55 Dong, 2020, Sex difference in prevalence of depression after stroke, Neurology, 94, e1973, 10.1212/WNL.0000000000009394 Doss, 2014, High prevalence of NMDA receptor IgA/IgM antibodies in different dementia types, Ann Clin Transl Neurol, 1, 822, 10.1002/acn3.120 Endres, 2022, Immune pathways in etiology, Acute phase, and chronic sequelae of ischemic stroke, Circ. Res., 130, 1167, 10.1161/CIRCRESAHA.121.319994 Fang, 2019, Effect of inflammation on the process of stroke rehabilitation and poststroke depression, Front. Psychiatr., 10, 184, 10.3389/fpsyt.2019.00184 Ferro, 2016, Neuropsychiatric sequelae of stroke, Nat. Rev. Neurol., 12, 269, 10.1038/nrneurol.2016.46 Finke, 2017, High prevalence of neuronal surface autoantibodies associated with cognitive deficits in cancer patients, J. Neurol., 264, 1968, 10.1007/s00415-017-8582-0 Hardingham, 2010, Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders, Nat. Rev. Neurosci., 11, 682, 10.1038/nrn2911 Hardingham, 2002, Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways, Nat. Neurosci., 5, 405, 10.1038/nn835 Hashimoto, 2009, Emerging role of glutamate in the pathophysiology of major depressive disorder, Brain Res. Rev., 61, 105, 10.1016/j.brainresrev.2009.05.005 Hatano, 1976, Experience from a multicentre stroke register: a preliminary report, Bull. World Health Organ., 54, 541 Hill, 1965 Iadarola, 2015, Ketamine and other N-methyl-D-aspartate receptor antagonists in the treatment of depression: a perspective review, Ther Adv Chronic Dis, 6, 97, 10.1177/2040622315579059 Jahn, 2018, [Criterion validity of the German version of the CES-D in the general population], Psychiatr. Prax., 45, 434 Kreye, 2016, Human cerebrospinal fluid monoclonal N-methyl-D-aspartate receptor autoantibodies are sufficient for encephalitis pathogenesis, Brain, 139, 2641, 10.1093/brain/aww208 Levite, 2014, J. Neural. Transm., 121, 1029, 10.1007/s00702-014-1193-3 Liman, 2013, Prediction of vascular risk after stroke - protocol and pilot data of the Prospective Cohort with Incident Stroke (PROSCIS), Int. J. Stroke, 8, 484, 10.1111/j.1747-4949.2012.00871.x Loubinoux, 2012, Post-stroke depression: mechanisms, translation and therapy, J. Cell Mol. Med., 16, 1961, 10.1111/j.1582-4934.2012.01555.x Pan, 2021, Multiple inducers and novel roles of autoantibodies against the obligatory NMDAR subunit NR1: a translational study from chronic life stress to brain injury, Mol. Psychiatr., 26, 2471, 10.1038/s41380-020-0672-1 Parikh, 1988, The sensitivity and specificity of the Center for Epidemiologic Studies Depression Scale in screening for post-stroke depression, Int. J. Psychiatr. Med., 18, 169, 10.2190/BH75-EUYA-4FM1-J7QA Pruss, 2012, IgA NMDA receptor antibodies are markers of synaptic immunity in slow cognitive impairment, Neurology, 78, 1743, 10.1212/WNL.0b013e318258300d Ramberger, 2015, Comparison of diagnostic accuracy of microscopy and flow cytometry in evaluating N-methyl-D-aspartate receptor antibodies in serum using a live cell-based assay, PLoS One, 10, 10.1371/journal.pone.0122037 Roth, 2020, Depressive symptoms after ischemic stroke: population-based comparisons of patients and caregivers with matched controls, Stroke, 51, 54, 10.1161/STROKEAHA.119.027039 Shrier, 2008, Reducing bias through directed acyclic graphs, BMC Med. Res. Methodol., 8, 70, 10.1186/1471-2288-8-70 Sperber, 2019, Serum anti-NMDA (N-Methyl-D-Aspartate)-Receptor antibodies and long-term clinical outcome after stroke (PROSCIS-B), Stroke, 50, 3213, 10.1161/STROKEAHA.119.026100 Sperber, 2022, Serum anti-NMDA-receptor antibodies and cognitive function after ischemic stroke (PROSCIS-B), J. Neurol., 269, 5521, 10.1007/s00415-022-11203-x Steiner, 2014, Prevalence of N-methyl-D-aspartate receptor autoantibodies in the peripheral blood: healthy control samples revisited, JAMA Psychiatr., 71, 838, 10.1001/jamapsychiatry.2014.469 Wenke, 2019, N-methyl-D-aspartate receptor dysfunction by unmutated human antibodies against the NR1 subunit, Ann. Neurol., 85, 771, 10.1002/ana.25460 Wijeratne, 2021, Understanding why post-stroke depression may Be the norm rather than the exception: the anatomical and neuroinflammatory correlates of post-stroke depression, J. Clin. Med., 10, 10.3390/jcm10081674 Zerche, 2015, Preexisting serum autoantibodies against the NMDAR subunit NR1 modulate evolution of lesion size in Acute ischemic stroke, Stroke, 46, 1180, 10.1161/STROKEAHA.114.008323