Depression in patients with hidradenitis suppurativa

Journal of the European Academy of Dermatology and Venereology - Tập 27 Số 4 - Trang 473-478 - 2013
Armanda Onderdijk1,2, Hessel H. van der Zee1, Solveig Esmann3, Søren Lophaven4, D Dufour3, Gregor B. E. Jemec3,5, Jurr Boer2,5
1Department of Dermatology and Immunology, Erasmus MC, University Medical Center, Rotterdam, Netherlands
2Department of Dermatology, Deventer Hospital, and
3Department of Dermatology, Roskilde Hospital, Health Sciences Faculty, University of Copenhagen, Roskilde, and
4Statistical Consultant, Denmark
5Thesse two authors share the senior authorship of this manuscript equally.

Tóm tắt

AbstractBackground  Hidradenitis suppurativa (HS) is a chronic recurrent inflammatory skin disease with abscess formation and scarring predominantly in the inverse areas. The disease is often difficult to treat and patients experience a decreased quality of life (QoL). It is hypothesized that depression is more common in HS patients than among other dermatological patients.Objectives  To evaluate the prevalence of depression in patients with HS.Methods  In total 211 HS patients were included in the study and 233 were dermatological control patients. Their QoL and depression scores were assessed using the Dermatology Life Quality Index (DLQI) and the Major Depression Inventory (MDI) questionnaires. HS severity was recorded with a questionnaire and Hurley stages were extracted from the case records.Results  The DLQI was significantly higher for HS patients than for the control patients, 8.4 ± 7.5 vs. 4.3 ± 5.6 (P < 0.0001) and correlated with Hurley stage severity scores. Mean MDI scores were significantly higher for HS patients, 11.0 vs. 7.2 (P < 0.0001). However, clinically defined depression rates according to the International Classification of Diseases, 10th edition (ICD‐10) criteria were not significantly higher in HS patients compared to controls (9% vs. 6%).Conclusions  HS is a chronic skin disease with major impact on QoL even when compared to other dermatological diseases. MDI scores in HS patients correlate with disease severity. This correlation could indicate that the MDI represents a valid measure of disease related morbidity that may serve as an outcome measure in future studies and a relevant point of intervention for individual patients.

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Thông tin
Thông tin xuất bản

Journal of the European Academy of Dermatology and Venereology

Tập 27 Số 4

473-478

Thông tin tác giả