Dengue Virus Type 2 Infections of Aedes aegypti Are Modulated by the Mosquito's RNA Interference Pathway

K Clyde, 2006, Recent advances in deciphering viral and host determinants of dengue virus replication and pathogenesis., J Virol, 80, 11418, 10.1128/JVI.01257-06

DJ Gubler, 2002, The global emergence/resurgence of arboviral diseases as public health problems., Arch Med Res, 33, 330, 10.1016/S0188-4409(02)00378-8

JG Rigau-Perez, 2006, Severe dengue: the need for new case definitions., Lancet Infect Dis, 6, 297, 10.1016/S1473-3099(06)70465-0

LC Harrington, 2001, Why do female Aedes aegypti (Diptera: Culicidae) feed preferentially and frequently on human blood?, J Med Entomol, 38, 411, 10.1603/0022-2585-38.3.411

MI Salazar, 2007, Dengue virus type 2: replication and tropisms in orally infected Aedes aegypti mosquitoes., BMC Microbiol, 7, 9, 10.1186/1471-2180-7-9

V Nene, 2007, Genome Sequence of Aedes aegypti, a Major Arbovirus Vector., Science, 316, 1718, 10.1126/science.1138878

RM Waterhouse, 2007, Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes., Science, 316, 1738, 10.1126/science.1139862

Z Xi, 2008, The Aedes aegypti toll pathway controls dengue virus infection., PLoS Pathog, 4, e1000098, 10.1371/journal.ppat.1000098

D Galiana-Arnoux, 2006, Essential function in vivo for Dicer-2 in host defense against RNA viruses in drosophila., Nat Immunol, 7, 590, 10.1038/ni1335

RP van Rij, 2006, The RNA silencing endonuclease Argonaute 2 mediates specific antiviral immunity in Drosophila melanogaster., Genes Dev, 20, 2985, 10.1101/gad.1482006

XH Wang, 2006, RNA interference directs innate immunity against viruses in adult Drosophila., Science, 312, 452, 10.1126/science.1125694

E Bernstein, 2001, Role for a bidentate ribonuclease in the initiation step of RNA interference., Nature, 409, 363, 10.1038/35053110

YS Lee, 2004, Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways., Cell, 117, 69, 10.1016/S0092-8674(04)00261-2

JW Myers, 2003, Recombinant Dicer efficiently converts large dsRNAs into siRNAs suitable for gene silencing., Nat Biotechnol, 21, 324, 10.1038/nbt792

SM Elbashir, 2001, RNA interference is mediated by 21- and 22-nucleotide RNAs., Genes Dev, 15, 188, 10.1101/gad.862301

AJ Hamilton, 1999, A species of small antisense RNA in posttranscriptional gene silencing in plants., Science, 286, 950, 10.1126/science.286.5441.950

X Liu, 2006, Dicer-2 and R2D2 coordinately bind siRNA to promote assembly of the siRISC complexes., RNA, 12, 1514, 10.1261/rna.101606

JW Pham, 2005, Molecular requirements for RNA-induced silencing complex assembly in the Drosophila RNA interference pathway., J Biol Chem, 280, 39278, 10.1074/jbc.M509202200

C Matranga, 2005, Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes., Cell, 123, 607, 10.1016/j.cell.2005.08.044

JB Preall, 2005, RNAi: RISC gets loaded., Cell, 123, 543, 10.1016/j.cell.2005.11.006

SM Hammond, 2001, Argonaute2, a link between genetic and biochemical analyses of RNAi., Science, 293, 1146, 10.1126/science.1064023

K Miyoshi, 2005, Slicer function of Drosophila Argonautes and its involvement in RISC formation., Genes Dev, 19, 2837, 10.1101/gad.1370605

AW Franz, 2006, Engineering RNA interference-based resistance to dengue virus type 2 in genetically modified Aedes aegypti., Proc Natl Acad Sci U S A, 103, 4198, 10.1073/pnas.0600479103

NT Hoa, 2003, Characterization of RNA interference in an Anopheles gambiae cell line., Insect Biochem Mol Biol, 33, 949, 10.1016/S0965-1748(03)00101-2

KM Keene, 2004, RNA interference acts as a natural antiviral response to O'nyong-nyong virus (Alphavirus; Togaviridae) infection of Anopheles gambiae., Proc Natl Acad Sci U S A, 101, 17240, 10.1073/pnas.0406983101

I Sanchez-Vargas, 2004, RNA interference, arthropod-borne viruses, and mosquitoes., Virus Res, 102, 65, 10.1016/j.virusres.2004.01.017

CL Campbell, 2008, Aedes aegypti uses RNA interference in defense against Sindbis virus infection., BMC Microbiol, 8, 47, 10.1186/1471-2180-8-47

J Richardson, 2006, Quantitative analysis of dengue-2 virus RNA during the extrinsic incubation period in individual Aedes aegypti., Am J Trop Med Hyg, 74, 132, 10.4269/ajtmh.2006.74.132

H Li, 2002, Induction and suppression of RNA silencing by an animal virus., Science, 296, 1319, 10.1126/science.1070948

BM Roth, 2004, Plant viral suppressors of RNA silencing., Virus Res, 102, 97, 10.1016/j.virusres.2004.01.020

BJ Geiss, 2005, Actively replicating West Nile virus is resistant to cytoplasmic delivery of siRNA., Virol J, 2, 53, 10.1186/1743-422X-2-53

PD Uchil, 2003, Architecture of the flaviviral replication complex. Protease, nuclease, and detergents reveal encasement within double-layered membrane compartments., J Biol Chem, 278, 24388, 10.1074/jbc.M301717200

F Weber, 2006, Double-stranded RNA is produced by positive-strand RNA viruses and DNA viruses but not in detectable amounts by negative-strand RNA viruses., J Virol, 80, 5059, 10.1128/JVI.80.10.5059-5064.2006

WC Black, 2002, Flavivirus susceptibility in Aedes aegypti., Arch Med Res, 33, 379, 10.1016/S0188-4409(02)00373-9

S Miller, 2006, Subcellular localization and membrane topology of the Dengue virus type 2 Non-structural protein 4B., J Biol Chem, 281, 8854, 10.1074/jbc.M512697200

A Molnar, 2005, Plant virus-derived small interfering RNAs originate predominantly from highly structured single-stranded viral RNAs., J Virol, 79, 7812, 10.1128/JVI.79.12.7812-7818.2005

S Schubert, 2005, Local RNA target structure influences siRNA efficacy: systematic analysis of intentionally designed binding regions., J Mol Biol, 348, 883, 10.1016/j.jmb.2005.03.011

KE Bennett, 2002, Variation in vector competence for dengue 2 virus among 24 collections of Aedes aegypti from Mexico and the United States., Am J Trop Med Hyg, 67, 85, 10.4269/ajtmh.2002.67.85

KE Bennett, 2005, Quantitative trait loci that control dengue-2 virus dissemination in the mosquito Aedes aegypti., Genetics, 170, 185, 10.1534/genetics.104.035634

JR Anderson, 2006, Aedes aegypti vectorial capacity is determined by the infecting genotype of dengue virus., Am J Trop Med Hyg, 75, 886, 10.4269/ajtmh.2006.75.886

PM Armstrong, 2001, Differential susceptibility of Aedes aegypti to infection by the American and Southeast Asian genotypes of dengue type 2 virus., Vector Borne Zoonotic Dis, 1, 159, 10.1089/153036601316977769

E Gomariz-Zilber, 1995, Drosophila C virus: experimental study of infectious yields and underlying pathology in Drosophila melanogaster laboratory populations., J Invertebr Pathol, 65, 243, 10.1006/jipa.1995.1037

SS Soldan, 2005, La Crosse virus nonstructural protein NSs counteracts the effects of short interfering RNA., J Virol, 79, 234, 10.1128/JVI.79.1.234-244.2005

G Blakqori, 2007, La Crosse bunyavirus nonstructural protein NSs serves to suppress the type I interferon system of mammalian hosts., J Virol, 81, 4991, 10.1128/JVI.01933-06

HL Chotkowski, 2008, West Nile virus infection of Drosophila melanogaster induces a protective RNAi response., Virology, 377, 197, 10.1016/j.virol.2008.04.021

D Sladowski, 1993, An improved MTT assay., J Immunol Methods, 157, 203, 10.1016/0022-1759(93)90088-O

H Takeuchi, 1991, An application of tetrazolium (MTT) colorimetric assay for the screening of anti-herpes simplex virus compounds., J Virol Methods, 33, 61, 10.1016/0166-0934(91)90008-N

CF Bosio, 1998, Quantitative genetics of vector competence for dengue-2 virus in Aedes aegypti., Am J Trop Med Hyg, 59, 965, 10.4269/ajtmh.1998.59.965

ZN Adelman, 2002, RNA silencing of dengue virus type 2 replication in transformed C6/36 mosquito cells transcribing an inverted-repeat RNA derived from the virus genome., J Virol, 76, 12925, 10.1128/JVI.76.24.12925-12933.2002

GS Pall, 2007, Carbodiimide-mediated cross-linking of RNA to nylon membranes improves the detection of siRNA, miRNA and piRNA by northern blot., Nucleic Acids Res, 35, e60, 10.1093/nar/gkm112