Demonstration of Multipotent Stem Cells in the Adult Human Endometrium by In Vitro Chondrogenesis

E Wolff1, Andrew B. Wolff2, Hongling Du3, Hugh S. Taylor3
1Department of Obstetrics, Gynecology and Reproductive Sciences Yale University School of Medicine New Haven Connecticut USA
2Department of Orthopedics and Rehabilitation, Yale University School of Medicine, New Haven, USA
3Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, USA

Tóm tắt

Từ khóa


Tài liệu tham khảo

Till JE, McCulloch CE A direct measurement of the radiation sensitivity of normal mouse bone marrow cells. Radiat Res. 1961;14:213–222.

Pittenger MF, Mackay AM, Beck SC, et al. Multilineage potential of adult human mesenchymal stem cells. Science. 1999;284(5411):143–147.

Lee RH, Kim B., Choi I., et al. Characterization and expression analysis of mesenchymal stem cells from human bone marrow and adipose tissue. Cell Physiol Biochem. 2004;14(4–6): 311–324.

Shih DT, Lee DC, Chen SC, et al. Isolation and characterization of neurogenic mesenchymal stem cells in human scalp tissue. Stem Cells. 2005;23(7):1012–1020.

Trubiani O., Di Primio R., Traini T., et al. Morphological and cytofluorimetric analysis of adult mesenchymal stem cells expanded ex vivo from periodontal ligament. Int J Immunopathol Pharmacol. 2005;18(2):213–221.

In’t Anker PS, Scherjon SA, et al. Isolation of mesenchymal stem cells of fetal or maternal origin from human placenta. Stem Cells. 2004;22(7):1338–1345.

Erices A., Conget P., Minguell JJ Mesenchymal progenitor cells in human umbilical cord blood. Br J Haematol. 2000; 109(1):235–242.

Roufosse CA, Direkze NC, Otto WR, Wright NA Circulating mesenchymal stem cells. Int J Biochem Cell Biol. 2004;36(4):585–597.

Lawson DA, Xin L., Lukacs RU, Cheng D., Witte ON Isolation and functional characterization of murine prostate stem cells. Proc Natl Acad Sci U S A. 2007;104(1):181–186.

Kattman SJ, Huber TL, Keller GM Multipotent flk-1+ cardiovascular progenitor cells give rise to the cardiomyocyte, endothelial, and vascular smooth muscle lineages. Dev Cell. 2006;11(5):723–732.

Moretti A., Caron L., Nakano A., et al. Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification. Cell. 2006;127(6):1151–1165.

De Coppi P., Bartsch G. Jr, Siddiqui MM, et al. Isolation of amniotic stem cell lines with potential for therapy. Nat Biotechnol. 2007;25(1):100–106.

Chan RW, Schwab KE, Gargett CE Clonogenicity of human endometrial epithelial and stromal cells. Biol Reprod. 2004; 70(6):1738–1750.

Schwab KE, Chan RW, Gargett CE Putative stem cell activity of human endometrial epithelial and stromal cells during the menstrual cycle. Fertil Steril. 2005;84(suppl 2):1124–1130.

Cervello I., Martinez-Conejero JA, Horcajadas JA, Pellicer A., Simon C. Identification, characterization and co-localization of label-retaining cell population in mouse endometrium with typical undifferentiated markers. Hum Reprod. 2007;22(1):45–51.

Cho NH, Park YK, Kim YT, Yang H., Kim SK Lifetime expression of stem cell markers in the uterine endometrium. Fertil Steril. 2004;81(2):403–407.

Matthai C., Horvat R., Noe M., et al. Oct-4 expression in human endometrium. Mol Hum Reprod. 2006;12(1):7–10.

Padykula HA, Coles LG, Okulicz WC, et al.The basalis of the primate endometrium: a bifunctional germinal compartment. Biol Reprod. 1989;40(3):681–690.

Taylor HS Endometrial cells derived from donor stem cells in bone marrow transplant recipients. JAMA. 2004;292(1):81–85.

Du H. Taylor HS Contribution of bone marrow derived stem cells to endometrium and endometriosis. Stem Cells. Epub ahead of print April 26, 2007.

Salamonsen LA Tissue injury and repair in the female human reproductive tract. Reproduction. 2003;125(3):301–311.

Meyer R. Knochengewebe im fotalen Uterus. Z Geburtsh Gynak. 1901;46:490.

Bird CC, Willis RA The production of smooth muscle by the endometrial stroma of the adult human uterus. J Pathol Bacteriol. 1965;90(1):75–81.

Hsu C. Endometrial ossification. Br J Obstet Gynaecol. 1975;82(10):836–839.

Roth E., Taylor HB Heterotopic cartilage in the uterus. Obstet Gynecol. 1966;27(6):838–844.

Blandamura S., Florea G., Chiarelli S., Rondinelli R., Ninfo V. Myometrial leiomyoma with chondroid lipoma-like areas. Histopathology. 2005;46(5):596–598.

Neumann H. Eine Knorpelinsel im Fundus uteri. Arch Gynaek. 1925;126:1.

Von Gierke E. Ueber Knorpelinseln in Uterusausschabungen. Zbl Allg Path. 1935;62:145.

Arici A., MacDonald PC, Casey ML Progestin regulation of interleukin-8 mRNA levels and protein synthesis in human endometrial stromal cells. J Steroid Biochem Mol Biol. 1996; 58(1):71–76.

Derfoul A., Perkins GL, Hall DJ, Tuan RS Glucocorticoids promote chondrogenic differentiation of adult human mesenchymal stem cells by enhancing expression of cartilage extracellular matrix genes. Stem Cells. 2006;24(6):1487–1495.

Arici A., Head JR, MacDonald PC, Casey ML Regulation of interleukin-8 gene expression in human endometrial cells in culture. Mol Cell Endocrinol. 1993;94(2):195–204.

Chan RW, Gargett CE Identification of label-retaining cells in mouse endometrium. Stem Cells. 2006;24(6):1529–1538.

Gargett CE Identification and characterisation of human endometrial stem/progenitor cells. Aust N Z J Obstet Gynaecol. 2006;46(3):250–253.

Gargett CE, Chan RW Label retaining cells in mouse endometrium: evidence for epithelial and stromal stem cells. J Soc Gynecol Invest. 2006;13(2 suppl):82A.

Blaise D., Kuentz M., Fortanier C., et al. Randomized trial of bone marrow versus lenograstim-primed blood cell allogeneic transplantation in patients with early-stage leukemia: a report from the Société Française de Greffe de Moelle. J Clin Oncol. 2000;18(3):537–546.

Morrison SJ, Wright DE, Weissman IL Cyclophosphamide/ granulocyte colony-stimulating factor induces hematopoietic stem cells to proliferate prior to mobilization. Proc Natl Acad Sci U S A. 1997;94(5):1908–1913.

Flomenberg N., Devine SM, Dipersio JF, et al. The use of AMD3100 plus G-CSF for autologous hematopoietic progenitor cell mobilization is superior to G-CSF alone. Blood. 2005;106(5):1867–1874.