Demonstration of HCV-RNA and HBV-DNA in the serum of HBsAg negative patients with hepatocellular carcinoma

Jaime Enríquez1, Klaus Fuchs2, Francisco José Martínez-Cerezo1, R Seminago1, P Madoz1, J. Torras1, M Roggendorf3
1Liver Unit, Department of Gastroenterology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
2The Max von Pettenkofer Institut, University of Munich, Germany
3Institut für Virologie, Universitätklinikum Essen, Germany

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Tài liệu tham khảo

Beasley RP, Hwang LY, Lin CC, Chien CS. Hepatocellular carcinoma and hepatitis B virus. Lancet 1981 (ii): 1129–1133.

Lai M, Chen P, Yang P, Sheu J, Shung J, Chen D. Identification and characterization of intrahepatic Hepatitis B virus DNA in HBsAg seronegative patients with chronic liver disease and hepatocellular carcinoma in Taiwan. Hepatology 1990; 12: 575–581.

Takada S, Gotoh Y, Hayashi Sh, Kobayasi M, Koike K. Integrated structures of HBV DNA in chronic hepatitis and hepatoma tissues. Gastroenterol Japon 1990; 25: 33–37.

Kekulé AS, Lauer U, Meyer M, Caselmann W, Hofschneider PH, Koshy R. The PreS2/S region of integrated hepatitis B virus DNA encodes a transcriptional transactivator. Nature 1990; 343: 457–461.

Takada S, Koike K. Transactivation function of a 3′ truncated X gene-cell fusion product from integrated hepatitis B virus DNA in chronic hepatitis tissues. Proc Natl Acad Sci USA 1990; 87: 5628–5632.

Fourel G, Trepo C, Bougesleret L, et al. Frequent activation of N-myc genes by hepadnavirus insertion in woodchuck liver tumors. Nature 1990; 347: 294–298.

Hsu T, Fourel G, Etiemble J, Tiollais P, Buendia M-A. Integration of hepatitis virus DNA near c-myc in woodchuck hepatocellular carcinoma. Gastroenterol Japon 1990; 25: 43–48.

Paterlini P, Gerken G, Nakajima E, Terre S, D'Errico A, Grigioni W, et al. Polymerase chain reaction to detect hepatits B virus DNA and RNA sequences in primary liver cancers from patients negative for hepatitis B surface antigen. N Eng J Med 1990; 323: 80–85.

Choo QL, Kuo G, Weiner AJ, Overby LR, Bradley DW, Houghton M. Isolation of a cDNA clone derived from a blood-borne non-A non-B viral hepatitis genome. Science 1989; 244: 359–362.

Esteban JI, Esteban R, Viladomiu L, et al. Hepatitis C virus antibodies among risk groups in Spain. Lancet 1989 (ii): 294–297.

Roggendorf M, Deinhardt F, Rasshofer R, et al. Antibodies to hepatitis C virus. Lancet 1989 (ii): 324–325.

Bruix J, Barrera JM, Calvet X, et al. Prevalence of antibodies to hepatitis C virus in Spanish patients with hepatocellular carcinoma and hepatic cirrhosis. Lancet 1989 (ii): 1004–1006.

Colombo M, Kuo G, Choo QL, et al. Prevalence of antibodies of hepatitis C virus in Italian patients with hepatocellular carcinoma. Lancet 1989 (ii): 1006–1008.

Farinati F, Fagiuoli S, De Maria N, et al. Anti-HCV positive hepatocellular carcinoma in cirrhosis. J Hepatol 1992; 14: 183–187.

Hasan F, Jeffers L, De Medina M, et al. Hepatitis C-associated hepatocellular carcinoma. Hepatology 1990; 12: 589–591.

Kew MC, Houghton M, Choo QL, Kuo G. Hepatitis C virus antibodies in southern African blacks with hepatocellular carcinoma. Lancet 1990; 335: 873–874.

Kiyosawa K, Sodeyama T, Tanaka E, et al. Interrelationship of blood transfusion, non-A, non-B hepatitis and hepatocellular carcinoma: Analysis by detection of antibody to Hepatitis C Virus. Hepatology 1990; 12: 671–675.

Lee S, Lee F, Wu J, Hwang S, Wang S, Lo K. The prevalence of anti-hepatitis C virus among Chinese patients with hepatocellular carcinoma. Cancer 1990; 69: 342–345.

Nishioka K, Watanabe J, Furuta S, et al. A high prevalence of antibody to the hepatitis C virus in patients with hepatocellular carcinoma in Japan. Cancer 1991; 67: 429–433.

Ohkoshi S, Kojima H, Tawaraya H, et al. Prevalence of antibody against non-A, non-B hepatitis virus in Japanese patients with hepatocellular carcinoma. Jpn J Cancer Res 1990; 81: 550–553.

Saito I, Miyamura T, Ohbayashi A, et al. Hepatitis C virus infection is associated with the development of hepatocellular carcinoma. Proc Natl Acad Sci USA 1990; 87: 6547–6549.

Tzonou A, Trichopoulos D, Kaklamani K, Zavitsanos X, Koumantaki Y, Hsieh C. Epidemiologic assessment of interactions of hepatitis-C virus with seromarkers of hepatitis-B and -D viruses, cirrhosis and tobacco smoking in hepatocellular carcinoma. Int J Cancer 1991; 49: 377–380.

Yu M, Tong M, Coursaget P, Ross R, Govindarajan S, Henderson E. Prevalence of Hepatitis B and C viral markers in black and white patients with hepatocellular carcinoma in the United States. J Nat Cancer Ins 1990; 82 (12): 1038–1041.

Fuchs K, Motz M, Schreier E, Zachoval R, Deinhart F, Roggendorf M. Characterization of nucleotide sequences from European hepatitis C virus isolates. Gene 1991; 103: 163–169.

Okamoto H, Okada S, Sugiyama Y, et al. The 5′-terminal sequence of hepatitis C virus genome. Japan J Exp Med 1990; 60: 167–177.

Zaaijer HL, Cuypers HTM, Reesink HW, et al. Reliability of polymerase chain reaction for detection of hepatitis C virus. Lancet 1993; 341: 722–724.

Valenzuela P, Quiroga M, Zaldivar J, et al. The nucleotide sequence of the hepatitis B viral genome and the identification of the major viral genes. In: Fields BN, Jaenichs R, Fox CF, eds. Animal virus genetics. New York: Academic Press, 1980: 55–70.

Sanger F, Nicklen S, Coulson AR. DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci USA 1977; 74: 5463–5467.

Kwok S, Higuchi H. Avoiding false positives with PCR. Nature 1989; 339: 237–238.

Domenech JM. Bioestadística. Métodos estadísticos para investigadores, 3rd ed. Barcelona: Ed. Herder, 1980.

Cristiano K, DiBisceglie AM, Hoofnagle JM, Feinstone SM. Hepatitis C viral RNA in serum of patients with chronic non-A, non-B hepatitis: Detection by the polymerase chain reaction using multiple primer sets. Hepatology 1991; 14: 51–55.

Farci P, Alter HJ, Wong D, et al. A long term study of hepatitis C virus replication in non-A, non-B hepatitis. N Engl J Med 1991; 325: 98–104.

Brillanti S, Barbara L, Miglioli M, Bonino F. Hepatitis C virus: A possible cause of chronic hepatitis in alcoholics. Lancet 1989 (ii): 1390–1391.

Ruíz J, Sangro B, Cuendo JI, et al. Hepatitis B and C viral infection in patients with hepatocellular carcinoma. Hepatology 1992; 16: 637–641.

Sheu J, Huang G, Shih L, et al. Hepatitis C and B viruses in Hepatitis B surface antigen-negative hepatocellular carcinoma. Gastroenterology 1992; 103: 1322–1327.