Delaying Radical Cystectomy After Neoadjuvant Chemotherapy for Muscle-invasive Bladder Cancer is Associated with Adverse Survival Outcomes

Spiess, 2017, Bladder cancer, version 5.2017, NCCN clinical practice guidelines in oncology, J Natl Compr Cancer Netw, 15, 1240, 10.6004/jnccn.2017.0156 Grossman, 2003, Neoadjuvant chemotherapy plus cystectomy compared with cystectomy alone for locally advanced bladder cancer, N Engl J Med, 349, 859, 10.1056/NEJMoa022148 Advanced Bladder Cancer Meta-analysis Collaboration, 2005, Neoadjuvant chemotherapy in invasive bladder cancer: update of a systematic review and meta-analysis of individual patient data, Eur Urol, 48, 202, 10.1016/j.eururo.2005.04.006 Advanced Bladder Cancer Meta-analysis Collaboration, 2005, Adjuvant chemotherapy in invasive bladder cancer: a systematic review and meta-analysis of individual patient data, Eur Urol, 48, 189, 10.1016/j.eururo.2005.04.005 Zaid, 2014, Trends in the utilization of neoadjuvant chemotherapy in muscle-invasive bladder cancer: results from the National Cancer Database, Urology, 83, 75, 10.1016/j.urology.2013.07.072 Cowan, 2014, Neoadjuvant chemotherapy use in bladder cancer: a survey of current practice and opinions, Adv Urol, 2014, 746298, 10.1155/2014/746298 Chang, 2003, Delaying radical cystectomy for muscle invasive bladder cancer results in worse pathological stage, J Urol, 170, 1085, 10.1097/01.ju.0000086828.26001.ca Gore, 2009, Mortality increases when radical cystectomy is delayed more than 12 weeks: results from a Surveillance, Epidemiology, and End Results-Medicare analysis, Cancer, 115, 988, 10.1002/cncr.24052 Weight, 2009, Lack of pathologic down-staging with neoadjuvant chemotherapy for muscle-invasive urothelial carcinoma of the bladder: a contemporary series, Cancer, 115, 792, 10.1002/cncr.24106 Bruins, 2016, The effect of the time interval between diagnosis of muscle-invasive bladder cancer and radical cystectomy on staging and survival: a Netherlands Cancer Registry analysis, Urol Oncol, 34, 10.1016/j.urolonc.2015.11.006 Alva, 2012, Efficient delivery of radical cystectomy after neoadjuvant chemotherapy for muscle-invasive bladder cancer: a multidisciplinary approach, Cancer, 118, 44, 10.1002/cncr.26240 Mmeje, 2018, Determining the optimal time for radical cystectomy following neoadjuvant chemotherapy, BJU Int, 122, 89, 10.1111/bju.14211 Charlson, 1987, A new method of classifying prognostic comorbidity in longitudinal studies: development and validation, J Chronic Dis, 40, 373, 10.1016/0021-9681(87)90171-8 Edge, 2010 Hussain, 2014, A randomized phase 2 trial of gemcitabine/cisplatin with or without cetuximab in patients with advanced urothelial carcinoma, Cancer, 120, 2684, 10.1002/cncr.28767 von der Maase, 2000, Gemcitabine and cisplatin versus methotrexate, vinblastine, doxorubicin, and cisplatin in advanced or metastatic bladder cancer: results of a large, randomized, multinational, multicenter, phase III study, J Clin Oncol, 18, 3068, 10.1200/JCO.2000.18.17.3068 Sánchez-Ortiz, 2003, An interval longer than 12 weeks between the diagnosis of muscle invasion and cystectomy is associated with worse outcome in bladder carcinoma, J Urol, 169, 110, 10.1016/S0022-5347(05)64047-5 Lee, 2006, Cystectomy delay more than 3 months from initial bladder cancer diagnosis results in decreased disease specific and overall survival, J Urol, 175, 1262, 10.1016/S0022-5347(05)00644-0 Mahmud, 2006, Effect of preoperative delay on survival in patients with bladder cancer undergoing cystectomy in Quebec: a population based study, J Urol, 175, 78, 10.1016/S0022-5347(05)00070-4 Liedberg, 2005, Treatment delay and prognosis in invasive bladder cancer, J Urol, 174, 1777, 10.1097/01.ju.0000177521.72678.61 Nielsen, 2007, A delay in radical cystectomy of >3 months is not associated with a worse clinical outcome, BJU Int, 100, 1015, 10.1111/j.1464-410X.2007.07132.x