Delayed inhibition of epidermal DNA synthesis after injection of an aqueous skin extract (Chalone)

Henry Hennings1, Kjell Elgjo1, Olav Hilmar Iversen1
1Institutt for Generell og Eksperimentell Patologi, Universitetet i Oslo, Oslo, Norway

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Baden, H. P., andS. Sviokla: The effect of chalone on epidermal DNA synthesis. Exp. Cell Res.50, 644–646 (1968).

Bailey, J. L.: Techniques in protein chemistry, second edit. Amsterdam: Elsevier 1967.

Baserga, R.: The relationship of the cell cycle to tumor growth and control of cell division: a review. Cancer Res.25, 581–595 (1965).

—R. D. Estensen, andR. O. Petersen: Inhibition of DNA synthesis in Ehrlich ascites cells by actinomycin D. II. The presynthetic block in the cell cycle. Proc. nat. Acad. Sci. (Wash.)54, 1141–1148 (1965).

Bates, R. R., J. S. Wortham, W. B. Counts, C. W. Dingman, andH. V. Gelboin: Inhibition by actinomycin D of DNA synthesis and skin tumorigenesis induced by 7,12-dimethylbenz (a)-anthracene. Cancer Res.28, 27–34 (1968).

Bollum, F. J., andV. R. Potter: Nucleic acid metabolism in regenerating rat liver. VII. Soluble enzymes which convert thymidine to thymidine phosphates and DNA. Cancer Res.19, 561–566 (1959).

Bullough, W. S.: The control of mitotic activity in adult mammalian tissues. Biol. Rev.37, 307–342 (1962).

—C. L. Hewett, andE. B. Laurence: The epidermal chalone: a preliminary attempt at isolation. Exp. Cell Res.36, 192–200 (1964).

—, andE. B. Laurence: The control of epidermal mitotic activity in the mouse. Proc. roy. Soc. B151, 517–536 (1960).

—— Mitotic control by internal secretion. The role of the chalone-adrenalin complex. Exp. Cell Res.33, 176–194 (1964).

— The role of glucocorticoid hormones in the control of epidermal mitosis. Cell Tiss. Kinet.1, 5–10 (1968).

—O. H. Iversen, andK. Elgjo: The vertebrate epidermal chalone. Nature (Lond.)214, 578–580 (1967).

—, andT. Rytömaa: Mitotic homeostasis. Nature (Lond.)205, 573–578 (1965).

Burton, K.: A study of the conditions and mechanisms of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid. Biochem. J.62, 315–323 (1956).

Cameron, I. L., andR. C. Greulich: Evidence for an essentially constant duration of DNA synthesis in renewing epithelia of the adult mouse. J. Cell Biol.18, 31–40 (1963).

Christophers, E., andO. Braun-Falco: Epidermale Regeneration am Meerschweinchenohr nach Hornschichtabriß. Eine autoradiographische Untersuchung. Arch. klin. exp. Derm.231, 85–96 (1967).

Cowdry, E. V.: Laboratory technique in biology and medicine. Baltimore: Williams & Wilkins 1948.

Finegold, M. J.: Control of cell multiplication in epidermis. Proc. Soc. exp. Biol. (N.Y.)119, 96–100 (1965).

Flamm, W. G., M. R. Banerjee, andW. B. Counts: Topical application of actinomycin D on mouse skin: effect on the synthesis of ribonucleic acid and protein. Cancer Res.26, 1349–1360 (1966).

Frankfurt, O. S.: Effect of hydrocortisone, adrenalin and actinomycin D on transition of cells to the DNA synthesis phase. Exp. Cell Res.52, 222–232 (1968).

Fujioka, M., M. Koga, andI. Lieberman: Metabolism of ribonucleic acid after partial hepatectomy. J. biol. Chem.238, 3401–3406 (1963).

Hell, E. A., andD. N. D. Cruickshank: The effect of injury upon the uptake of3H-thymidine by guinea pig epidermis. Exp. Cell Res.31, 128–139 (1963).

Hennings, H.: Unpublished results, 1969. 18–24 hours after 5 strippings with cellophane tape, thymidine-3H incorporation into epidermal DNA was increased 2—3 times the control value.

—, andR. K. Boutwell: The effect of croton oil on DNA, RNA and protein synthesis in mouse skin. Proc. Amer. Ass. Cancer Res.9, 29 (1968).

—H. C. Smith, N. H. Colburn, andR. K. Boutwell: Inhibition by actinomycin D of DNA and RNA synthesis and of skin carcinogenesis initiated by 7,12-dimethylbenz [a]-anthracene or β-propiolactone. Cancer Res.28, 543–552 (1968).

Hondius Boldingh, W., andE. B. Laurence: Extraction, purification and preliminary characterisation of the epidermal chalone: a tissue specific mitotic inhibitor obtained from vertebrate skin. Europ. J. Biochem.5, 191–198 (1968).

Iversen, O. H.: Cell metabolism in experimental skin carcinogenesis. Acta path, microbiol. scand.50, 17–24 (1960).

- Chalones of the skin. In: Ciba Symp. on Homeostatic Regulators (G. E. W. Wolstenholme andM. O’Connor, eds.). London: Churchill Ltd. 1969 (in press).

—E. Aandahl, andK. Elgjo: The effect of an epidermis-specific mitotic inhibitor (chalone) extracted from epidermal cells. Acta path. microbiol. scand.64, 506–510 (1965).

Iversen, O. H., andA. Evensen: Experimental skin carcinogenesis in mice. Acta path. miorobiol. scand., Suppl. 156 (1962).

Mercer, E. H.: Keratin and Keratinization. London: Pergamon Press 1961.

Mueller, G. C., andK. Kajiwara: Actinomycin D and p-flurophenylalanine, inhibitors of nuclear replication in HeLa cells. Biochim. biophys. Acta (Amst.)119, 557–565 (1966).

——,E. Stubblefield, andR. Rueckert: Molecular events in the reproduction of animal cells. I. Cancer Res.22, 1084–1090 (1962).

Nome, O.: Personal communication, 1969.

Prescott, D. M.: Regulation of cell reproduction. Cancer Res.28, 1815–1820 (1968).

Rytömaa, R., andK. Kiviniemi: Control of granulocyte production. II. Mode of action of chalone and antichalone. Cell Tiss. kinet.1, 341–350 (1968).

Schneider, W. C.: Determination of nucleic acids in tissues by pentose analysis. In: Methods in enzymology, vol.3, p. 680–684 (S. P. Colowick andN. O. Kaplan, eds.). New York: Academic press 1957.

Shinozuka, H., andA.C. Ritchie: Pretreatment with croton oil, DNA synthesis, and carcinogenesis by carcinogen followed by croton oil. Int. J. Cancer2, 77–84 (1967).

Terayama, H., andM. Sasada: Activity of the cell-sap factor inhibiting DNA synthesis of rat ascites hepatoma cells in normal tissues, various malignant and minimal deviation hepatomas, as well as livers during the course of carcinogenesis. Gann59, 51–59 (1968).

Volm, M., V. Kinzel, U. Mohr, andR. Süss: Inactivation of tissue-specific inhibitors by a carcinogen (diethylnitrosamine). Experientia (Basel)25 (1), 68–69 (1969).