Defining the osteoarthritis patient: back to the future

Heberden, 1816 Martel-Pelletier, 2016, Osteoarthritis, Nat Rev Dis Primers, 13, 16072, 10.1038/nrdp.2016.72 Loeser, 2012, Osteoarthritis: a disease of the joint as an organ, Arthritis Rheum, 64, 1697, 10.1002/art.34453 Pelletier, 2001, Osteoarthritis, an inflammatory disease: potential implication for the selection of new therapeutic targets, Arthritis Rheum, 44, 1237, 10.1002/1529-0131(200106)44:6<1237::AID-ART214>3.0.CO;2-F Malemud, 2015, Biologic basis of osteoarthritis: state of the evidence, Curr Opin Rheumatol, 27, 289, 10.1097/BOR.0000000000000162 Kalaitzoglou, 2017, Innate immune responses and osteoarthritis, Curr Rheumatol Rep, 19, 45, 10.1007/s11926-017-0672-6 Warner, 2017, Genetic association studies in osteoarthritis: is it fairytale?, Curr Opin Rheumatol, 29, 103, 10.1097/BOR.0000000000000352 Dequeker, 2008, The history of osteoarthritis-osteoarthrosis, Ann Rheum Dis, 67, 5, 10.1136/ard.2007.079764 Garrod, 1890 Willy, 2008, Richard von Volkmann: surgeon and Renaissance man, Clin Orthop Relat Res, 466, 500, 10.1007/s11999-007-0007-4 Jones, 1909 Jones, 1910, Arthritis deformans, Proc R Soc Med, 3, 85 Garrod, 1910, Discussion on arthritis deformans, Proc R Soc Med, 3, 99 Parish, 1963, An historical approach to the nomenclature of rheumatoid arthritis, Arthritis Rheum, 6, 138, 10.1002/art.1780060206 Benedek, 1999, When did “osteo-arthritis” become osteoarthritis?, J Rheumatol, 26, 1374 Bauer, 1941, Osteo-arthritis deformans of the temporomandibular joint, Am J Pathol, 17, 129 Robinson, 2016, Low-grade inflammation as a key mediator of the pathogenesis of osteoarthritis, Nat Rev Rheumatol, 12, 580, 10.1038/nrrheum.2016.136 Forsbrook, 1893 Burt, 1914, The production of osteophytes and exostoses in chronic gout and arthritis deformans, Proc R Soc Med, 7, 45 Garrod, 1924, Discussion on “The etiology and treatment of osteo-arthritis and rheumatoid arthritis”, Proc R Soc Med, 17, 1 Brandt, 2009, Commentary: is it useful to subset “primary” osteoarthritis? A critique based on evidence regarding the etiopathogenesis of osteoarthritis, Semin Arthritis Rheum, 39, 81, 10.1016/j.semarthrit.2009.06.001 Berenbaum, 2013, Osteoarthritis as an inflammatory disease (osteoarthritis is not osteoarthrosis!), Osteoarthr Cartil, 21, 16, 10.1016/j.joca.2012.11.012 Garrod, 1888, Nervous origin of rheumatoid arthritis, Med Chir Trans, 71, 89, 10.1177/095952878807100107 Spender, 1889, The early symptoms and early treatment of osteoarthritis (review of his book), Br Med J, 1, 1232 Ulrich-Lai, 2009, Neural regulation of endocrine and autonomic stress responses, Nat Rev Neurosci, 10, 397, 10.1038/nrn2647 Heidt, 2014, Chronic variable stress activates hematopoietic stem cells, Nat Med, 20, 754, 10.1038/nm.3589 Dobson, 2015, Addressing the global burden of trauma in major surgery, Front Surg, 2, 43, 10.3389/fsurg.2015.00043 Grill, 2009, The nucleus tractus solitarius: a portal for visceral afferent signal processing, energy status assessment and integration of their combined effects on food intake, Int J Obes (Lond), 33, S11, 10.1038/ijo.2009.10 Bonaz, 2016, Autonomic dysfunction: a predictive factor of risk to develop rheumatoid arthritis?, EBioMedicine, 6, 20, 10.1016/j.ebiom.2016.03.005 Thayer, 2009, Vagal tone and the inflammatory reflex, Clevel Clin J Med, 76, S23, 10.3949/ccjm.76.s2.05 Tracey, 2009, Reflex control of immunity, Nat Rev Immunol, 9, 418, 10.1038/nri2566 Pawelec, 2014, Inflammation, ageing and chronic disease, Curr Opin Immunol, 29, 23, 10.1016/j.coi.2014.03.007 Straub, 2017, The brain and immune system prompt energy shortage in chronic inflammation and ageing, Nat Rev Rheumatol, 12, 743, 10.1038/nrrheum.2017.172 Grässel, 2017, Peripheral nerve fibers and their neurotransmitters in osteoarthritis pathology, Int J Mol Sci, 18, 5, 10.3390/ijms18050931 Schaible, 2012, Mechanisms of chronic pain in osteoarthritis, Curr Rheumatol Rep, 14, 549, 10.1007/s11926-012-0279-x Kodama, 2017, Bidirectional communication between sensory neurons and osteoblasts in an in vitro coculture system, FEBS Lett, 591, 527, 10.1002/1873-3468.12561 Schwab, 1998, Innervation pattern of different cartilaginous tissues in the rat, Acta Anat, 163, 184, 10.1159/000046497 Koopman, 2017, Balancing the autonomic nervous system to reduce inflammation in rheumatoid arthritis, J Intern Med, 282, 64, 10.1111/joim.12626 Driban, 2016, Exploratory analysis of osteoarthritis progression among medication users: data from the Osteoarthritis Initiative, Ther Adv Musculoskel Dis, 8, 207, 10.1177/1759720X16664323 Kim, 2010, Reduction in endocannabinoid tone is a homeostatic mechanism for specific inhibitory synapses, Nat Neurosci, 13, 592, 10.1038/nn.2517 Turrigiano, 2012, Homeostatic synaptic plasticity: local and global mechanisms for stabilizing neuronal function, Cold Spring Harb Perspect Biol, 4, 10.1101/cshperspect.a005736 Dobson, 2014, Addressing the global burden of sepsis: importance of a systems-based approach, Crit Care Med, 42, e797, 10.1097/CCM.0000000000000595 Mueller, 2017, Systems approaches in osteoarthritis: identifying routes to novel diagnostic and therapeutic strategies, J Orthop Res, 35, 1573, 10.1002/jor.23563