Deep breathing exercises with positive expiratory pressure in patients with multiple sclerosis – a randomized controlled trial

Clinical Respiratory Journal - Tập 10 Số 6 - Trang 698-706 - 2016
Elisabeth Westerdahl1, Anna Wittrin2, Margareta Kånåhols2, Martin Gunnarsson2, Ylva Nilsagård3
1Faculty of Medicine and Health Surgery Örebro University Örebro Sweden
2Faculty of Medicine and Health Department of Neurology and Neurophysiology Örebro University Örebro Sweden
3Faculty of Medicine and Health Medicine Örebro University Örebro Sweden

Tóm tắt

AbstractIntroductionBreathing exercises with positive expiratory pressure are often recommended to patients with advanced neurological deficits, but the potential benefit in multiple sclerosis (MS) patients with mild and moderate symptoms has not yet been investigated in randomized controlled trials.ObjectivesTo study the effects of 2 months of home‐based breathing exercises for patients with mild to moderate MS on respiratory muscle strength, lung function, and subjective breathing and health status outcomes.MethodsForty‐eight patients with MS according to the revised McDonald criteria were enrolled in a randomized controlled trial. Patients performing breathing exercises (n = 23) were compared with a control group (n = 25) performing no breathing exercises. The breathing exercises were performed with a positive expiratory pressure device (10–15 cmH2O) and consisted of 30 slow deep breaths performed twice a day for 2 months. Respiratory muscle strength (maximal inspiratory and expiratory pressure at the mouth), spirometry, oxygenation, thoracic excursion, subjective perceptions of breathing and self‐reported health status were evaluated before and after the intervention period.ResultsFollowing the intervention, there was a significant difference between the breathing group and the control group regarding the relative change in lung function, favoring the breathing group (vital capacity: P < 0.043; forced vital capacity: P < 0.025). There were no other significant differences between the groups.ConclusionBreathing exercises may be beneficial in patients with mild to moderate stages of MS. However, the clinical significance needs to be clarified, and it remains to be seen whether a sustainable effect in delaying the development of respiratory dysfunction in MS can be obtained.

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Clinical Respiratory Journal

Tập 10 Số 6

698-706

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