Decipher the action mechanism of Simiao Pill in the treatment of knee osteoarthritis by integrating network pharmacology

Journal of Herbal Medicine - Tập 42 - Trang 100777 - 2023
Mengjing Cheng1, Mingchao Hong2, Feipeng Hu1, Wenhua Liu1
1Department of Orthopaedic Surgery, The Orthopaedic Hospital of Yongkang, Yongkang, Zhejiang, China
2Department of Rehabilitation, People's Hospital of Pujiang, Pujiang, Zhejiang, China

Tài liệu tham khảo

Ali, 2021, In vitro study of licorice on IL-1β-induced chondrocytes and in silico approach for osteoarthritis, Pharmaceuticals (Basel), 14, 1337, 10.3390/ph14121337 Chen, 2020, LncRNA LOXL1-AS1 is transcriptionally activated by JUND and contributes to osteoarthritis progression via targeting the miR-423-5p/KDM5C axis, Life Sciences, 258, 10.1016/j.lfs.2020.118095 Chin, 2014, cytoHubba: identifying hub objects and sub-networks from complex interactome, BMC Systems Biology, 8 Suppl 4, S11, 10.1186/1752-0509-8-S4-S11 Chung, 2020, Arsenic induces human chondrocyte senescence and accelerates rat articular cartilage aging, Archives of Toxicology, 94, 89, 10.1007/s00204-019-02607-2 Dai, 2014, Association of single nucleotide polymorphisms in estrogen receptor alpha gene with susceptibility to knee osteoarthritis: a case-control study in a Chinese han population, BioMed Research International, 2014, 10.1155/2014/151457 Damen, 2019, Prevalence and development of hip and knee osteoarthritis according to American College of Rheumatology criteria in the CHECK cohort, Arthritis Research and Therapy, 21, 4, 10.1186/s13075-018-1785-7 Donati Giulio, 2022, MYC and therapy resistance in cancer: risks and opportunities, Molecular Oncology, 16, 3828 Duan, 2015, Vegfa regulates perichondrial vascularity and osteoblast differentiation in bone development, Development, 142, 1984, 10.1242/dev.117952 Guan, 2020, Low-intensity pulsed ultrasound inhibits VEGFA expression in chondrocytes and protects against cartilage degeneration in experimental osteoarthritis, FEBS Open Bio, 10, 434, 10.1002/2211-5463.12801 Hong, 2017, MicroRNA-143 and -145 modulate the phenotype of synovial fibroblasts in rheumatoid arthritis, Experimental and Molecular Medicine, 49, 10.1038/emm.2017.108 Huang, 2018, Kaempferol inhibits interleukin‑1β stimulated matrix metalloproteinasesby suppressing the mapk‑associated erk and p38 signaling pathways, Molecular Medicine Reports, 18, 2697 Huang, 2022, αTruncated lubricin glycans in osteoarthritis stimulate the synoviocyte secretion of VEGFA, IL-8, and MIP-1: interplay between -linked glycosylation and inflammatory cytokines, Frontiers in Molecular Biosciences, 9 J M C, 2017, Negative regulators of jak/stat signaling in rheumatoid arthritis and osteoarthritis, International Journal of Molecular Sciences, 18, 484, 10.3390/ijms18030484 Ji Min, 2021, Synovial fluid of patient with rheumatoid arthritis enhanced osmotic sensitivity through the cytotoxic edema module in synoviocytes, Frontiers in Cell and Developmental Biology, 9 Katz Jeffrey, 2021, Diagnosis and treatment of hip and knee osteoarthritis: a review, JAMA, 325, 568, 10.1001/jama.2020.22171 Krishnasamy, 2018, The role of skeletal muscle in the pathophysiology and management of knee osteoarthritis, Rheumatology (Oxford), 57, iv22, 10.1093/rheumatology/kex515 Li, 2022, Comparative metabolomics study of Tartary (Fagopyrum tataricum (L.) Gaertn) and common (Fagopyrum esculentum Moench) buckwheat seeds, Food Chemistry, 371, 10.1016/j.foodchem.2021.131125 Li, 2021, Chitosan oligosaccharides packaged into rat adipose mesenchymal stem cells-derived extracellular vesicles facilitating cartilage injury repair and alleviating osteoarthritis, Journal of Nanobiotechnology, 19, 343 Lin, 2017, Inhibition of interleukin-6 function attenuates the central sensitization and pain behavior induced by osteoarthritis, European Journal of Pharmacology, 811, 260, 10.1016/j.ejphar.2017.06.032 Lin, 2022, The efficacy and safety of Chinese herbal medicine in the treatment of knee osteoarthritis: an updated systematic review and meta-analysis of 56 randomized controlled trials, Oxidative Medicine and Cellular Longevity Liu, 2022, Type H vessels-a bridge connecting subchondral bone remodelling and articular cartilage degeneration in osteoarthritis development, Rheumatology (Oxford), 62, 1436, 10.1093/rheumatology/keac539 Loucks, 2023, The multifaceted role of mast cells in joint inflammation and arthritis, Osteoarthritis Cartilage, 567, 10.1016/j.joca.2023.01.005 Ma, 2021, Bioinformatic analysis reveals an exosomal miRNA-mRNA network in colorectal cancer, BMC Medical Genomics, 14, 60, 10.1186/s12920-021-00905-2 Nagao, 2017, Vascular endothelial growth factor in cartilage development and osteoarthritis, Scientific Reports, 7, 13027, 10.1038/s41598-017-13417-w Persson Monica, 2020, Predicting response to topical non-steroidal anti-inflammatory drugs in osteoarthritis: an individual patient data meta-analysis of randomized controlled trials, Rheumatology (Oxford), 59, 2207, 10.1093/rheumatology/keaa113 Phinyomark, 2016, Gender differences in gait kinematics for patients with knee osteoarthritis, BMC Musculoskeletal Disorders, 17, 157, 10.1186/s12891-016-1013-z Pomilio Alicia, 2022, Dietary anthocyanins balance immune signs in osteoarthritis and obesity - update of human in vitro studies and clinical trials, Critical Reviews in Food Science and Nutrition, 1, 10.1080/10408398.2022.2124948 Reimand, 2019, Pathway enrichment analysis and visualization of omics data using g: Profiler, GSEA, Cytoscape and Enrichment Map, Nature Protocols, 14, 482, 10.1038/s41596-018-0103-9 Riegger, 2020, Crucial role of the terminal complement complex in chondrocyte death and hypertrophy after cartilage trauma, Osteoarthritis and Cartilage, 28, 685 Riis, 2016, Synovitis assessed on static and dynamic contrast-enhanced magnetic resonance imaging and its association with pain in knee osteoarthritis: a cross-sectional study, European Journal of Radiology, 85, 1099, 10.1016/j.ejrad.2016.03.017 Sepulveda, 2020, Using R and bioconductor in clinical genomics and transcriptomics, The Journal of Molecular Diagnostics, 22, 3 Xiaoqing, 2022, Calycosin mitigates chondrocyte inflammation and apoptosis by inhibiting the PI3K/AKT and NF-κB pathways, Journal of Ethnopharmacology, 297 Sun, 2020, The pi3k/akt/mtor signaling pathway in osteoarthritis: a narrative review, Osteoarthritis and Cartilage, 28, 400, 10.1016/j.joca.2020.02.027 Sun, 2022, Network pharmacology-based analysis of the potential biological mechanisms of coix seed against colorectal cancer, Evidence-Based Complementary and Alternative Medicine, 2022, 10.1155/2022/9261768 Szklarczyk, 2021, The STRING database in 2021: customizable protein-protein networks, and functional characterization of user-uploaded gene/measurement sets, Nucleic Acids Research, 49, D605, 10.1093/nar/gkaa1074 UniProt Consortium, 2021, UniProt: the universal protein knowledgebase in 2021, Nucleic Acids Research, 49, D480, 10.1093/nar/gkaa1100 Wang, 2020, Mechanism of traditional Chinese medicine in treating knee osteoarthritis, Journal of Pain Research, 13, 1421, 10.2147/JPR.S247827 Wang, 2022, Novel role of estrogen receptor-α on regulating chondrocyte phenotype and response to mechanical loading, Osteoarthritis and Cartilage, 30, 302 Wang, 2022, Stage-specific and location-specific cartilage calcification in osteoarthritis development, Annals of the Rheumatic Diseases, 2022 Chen, 2023, Identification and validation of BCL6 and VEGFA as biomarkers and ageing patterns correlating with immune infiltrates in OA progression, Sci Rep., 13, 2558, 10.1038/s41598-023-28000-9 Xiong, 2022, Mechanisms and molecular targets of BuShenHuoXue formula for osteoarthritis, ACS Omega, 7, 4703, 10.1021/acsomega.1c07270 Xu, 2020, Observation on the treatment of early damp-heat obstructive knee osteoarthritis with Simiao Pill, Guangxi Traditional Chinese Medicine, 43, 17 Yu, 2022, Identification of key candidate genes and biological pathways in the synovial tissue of patients with rheumatoid arthritis, Experimental and Therapeutic Medicine, 23, 368, 10.3892/etm.2022.11295 Yu, 2012, clusterProfiler: an R package for comparing biological themes among gene clusters, OMICS, 16, 284, 10.1089/omi.2011.0118 Zupan, 2018, VEGF-A is associated with early degenerative changes in cartilage and subchondral bone, Growth Factors, 36, 263, 10.1080/08977194.2019.1570926