De novo fatty acid synthesis at the mitotic exit is required to complete cellular division
Tóm tắt
Từ khóa
Tài liệu tham khảo
Bergeron, 1970, Phospholipid synthesis and degradation during the life-cycle of P815Y mast cells synchronized with excess of thymidine, Biochem J, 119, 489, 10.1042/bj1190489
Warmsley, 1970, The use of conventional and zonal centrifugation to study the life cycle of mammalian cells. Phospholipid and macromolecular synthesis in neoplastic mast cells, Biochem J, 119, 493, 10.1042/bj1190493
Graham, 1973, Sequence of events in plasma membrane assembly during the cell cycle, Nature, 246, 291, 10.1038/246291a0
Jackowski, 1994, Coordination of membrane phospholipid synthesis with the cell cycle, J Biol Chem, 269, 3858, 10.1016/S0021-9258(17)41939-9
Northwood, 1999, Shuttling of CTP:Phosphocholine cytidylyltransferase between the nucleus and endoplasmic reticulum accompanies the wave of phosphatidylcholine synthesis during the G(0) --> G(1) transition, J Biol Chem, 274, 26240, 10.1074/jbc.274.37.26240
Golfman, 2001, Transcription of the CTP:phosphocholine cytidylyltransferase alpha gene is enhanced during the S phase of the cell cycle, J Biol Chem, 276, 43688, 10.1074/jbc.M108170200
Manguikian, 2004, Cell cycle dependence of group VIA calcium-independent phospholipase A2 activity, J Biol Chem, 279, 52881, 10.1074/jbc.M410659200
Banchio, 2004, Phosphorylation of Sp1 by cyclin-dependent kinase 2 modulates the role of Sp1 in CTP:phosphocholine cytidylyltransferase alpha regulation during the S phase of the cell cycle, J Biol Chem, 279, 40220, 10.1074/jbc.M406468200
Tercé, 1994, Requirement of phosphatidylcholine for normal progression through the cell cycle in C3H/10T1/2 fibroblasts, J Lipid Res, 35, 2130, 10.1016/S0022-2275(20)39919-3
Cui, 1996, A genetic defect in phosphatidylcholine biosynthesis triggers apoptosis in Chinese hamster ovary cells, J Biol Chem, 271, 14668, 10.1074/jbc.271.25.14668
Bluemink, 1973, New membrane formation during cytokinesis in normal and cytochalasin B-treated eggs of Xenopus laevis. I. Electron microscope observations, J Cell Biol, 59, 89, 10.1083/jcb.59.1.89
Shuster, 2002, Targeted new membrane addition in the cleavage furrow is a late, separate event in cytokinesis, Proc Natl Acad Sci U S A, 99, 3633, 10.1073/pnas.052342699
Boucrot, 2007, Endosomal recycling controls plasma membrane area during mitosis, Proc Natl Acad Sci U S A, 104, 7939, 10.1073/pnas.0702511104
Bosmann, 1970, Synthesis of glycoprotein, glycolipid, protein, and lipid in synchronized L5178Y cells, J Cell Biol, 45, 23, 10.1083/jcb.45.1.23
Kobayashi, 1989, Lipid transport during mitosis. Alternative pathways for delivery of newly synthesized lipids to the cell surface, J Biol Chem, 264, 5966, 10.1016/S0021-9258(18)83644-4
Lin, 2007, Phospholipids are synthesized in the G2/M phase of the cell cycle, Int J Biochem Cell Biol, 39, 597, 10.1016/j.biocel.2006.10.011
Ellenberg, 1997, Nuclear membrane dynamics and reassembly in living cells: targeting of an inner nuclear membrane protein in interphase and mitosis, J Cell Biol, 138, 1193, 10.1083/jcb.138.6.1193
Anderson, 2007, Nuclear envelope formation by chromatin-mediated reorganization of the endoplasmic reticulum, Nat Cell Biol, 9, 1160, 10.1038/ncb1636
Kuhajda, 1994, Fatty acid synthesis: a potential selective target for antineoplastic therapy, Proc Natl Acad Sci U S A, 91, 6379, 10.1073/pnas.91.14.6379
Kuhajda, 2006, Fatty acid synthase and cancer: new application of an old pathway, Cancer Res, 66, 5977, 10.1158/0008-5472.CAN-05-4673
Flavin, 2010, Fatty acid synthase as a potential therapeutic target in cancer, Future Oncol, 6, 551, 10.2217/fon.10.11
Zhang, 2010, Palmitate impairs cytokinesis associated with RhoA inhibition, Cell Res, 20, 492, 10.1038/cr.2010.33
Banko, 2011, Chemical genetic screen for AMPKα2 substrates uncovers a network of proteins involved in mitosis, Mol Cell, 44, 878, 10.1016/j.molcel.2011.11.005
Bengoechea-Alonso, 2005, Hyperphosphorylation regulates the activity of SREBP1 during mitosis, Proc Natl Acad Sci U S A, 102, 11681, 10.1073/pnas.0501494102
Bengoechea-Alonso, 2006, Cdk1/cyclin B-mediated phosphorylation stabilizes SREBP1 during mitosis, Cell Cycle, 5, 1708, 10.4161/cc.5.15.3131
Vander Heiden, 2011, Targeting cancer metabolism: a therapeutic window opens, Nat Rev Drug Discov, 10, 671, 10.1038/nrd3504
Almeida, 2010, E3 ubiquitin ligase APC/C-Cdh1 accounts for the Warburg effect by linking glycolysis to cell proliferation, Proc Natl Acad Sci U S A, 107, 738, 10.1073/pnas.0913668107
Ray, 2009, Cell cycle regulation of the BRCA1/acetyl-CoA-carboxylase complex, Biochem Biophys Res Commun, 378, 615, 10.1016/j.bbrc.2008.11.090
Wieprecht, 1996, Evidence for phosphorylation of CTP:phosphocholine cytidylyltransferase by multiple proline-directed protein kinases, J Biol Chem, 271, 9955, 10.1074/jbc.271.17.9955
Shah, 2001, Cell cycle-mediated drug resistance: an emerging concept in cancer therapy, Clin Cancer Res, 7, 2168
Bettuzzi, 1999, Coordinate changes of polyamine metabolism regulatory proteins during the cell cycle of normal human dermal fibroblasts, FEBS Lett, 446, 18, 10.1016/S0014-5793(99)00182-9
Brand, 1988, Cell-cycle-related metabolic and enzymatic events in proliferating rat thymocytes, Eur J Biochem, 172, 695, 10.1111/j.1432-1033.1988.tb13944.x
Geley, 2001, Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint, J Cell Biol, 153, 137, 10.1083/jcb.153.1.137
Clute, 1999, Temporal and spatial control of cyclin B1 destruction in metaphase, Nat Cell Biol, 1, 82, 10.1038/10049
Zadra, 2014, A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis, EMBO Mol Med, 10.1002/emmm.201302734
Vazquez-Martin, 2009, The active form of the metabolic sensor: AMP-activated protein kinase (AMPK) directly binds the mitotic apparatus and travels from centrosomes to the spindle midzone during mitosis and cytokinesis, Cell Cycle, 8, 2385, 10.4161/cc.8.15.9082
Jackowski, 1996, Cell cycle regulation of membrane phospholipid metabolism, J Biol Chem, 271, 20219, 10.1074/jbc.271.34.20219
Saitoh, 1996, Aberrant mitosis in fission yeast mutants defective in fatty acid synthetase and acetyl CoA carboxylase, J Cell Biol, 134, 949, 10.1083/jcb.134.4.949
Al-Feel, 2003, A Saccharomyces cerevisiae mutant strain defective in acetyl-CoA carboxylase arrests at the G2/M phase of the cell cycle, Proc Natl Acad Sci U S A, 100, 3095, 10.1073/pnas.0538069100
Li, 2001, Pharmacological inhibition of fatty acid synthase activity produces both cytostatic and cytotoxic effects modulated by p53, Cancer Res, 61, 1493
Gao, 2006, Growth arrest induced by C75, A fatty acid synthase inhibitor, was partially modulated by p38 MAPK but not by p53 in human hepatocellular carcinoma, Cancer Biol Ther, 5, 978, 10.4161/cbt.5.8.2883
Horiguchi, 2008, Pharmacological inhibitor of fatty acid synthase suppresses growth and invasiveness of renal cancer cells, J Urol, 180, 729, 10.1016/j.juro.2008.03.186
Knowles, 2007, Genome-wide changes accompanying knockdown of fatty acid synthase in breast cancer, BMC Genomics, 8, 168, 10.1186/1471-2164-8-168
Niculescu, 2007, Lymphocyte gene expression in subjects fed a low-choline diet differs between those who develop organ dysfunction and those who do not, Am J Clin Nutr, 86, 230, 10.1093/ajcn/86.1.230
Modolell, 1979, Disturbance of phospholipid metabolism during the selective destruction of tumor cells induced by alkyl-lysophospholipids, Cancer Res, 39, 4681
Engebraaten, 1991, Effect of alkyl-lysophospholipid on glioblastoma cell invasion into fetal rat brain tissue in vitro, Cancer Res, 51, 1713
Boggs, 1995, Lysophosphatidylcholine attenuates the cytotoxic effects of the antineoplastic phospholipid 1-O-octadecyl-2-O-methyl-rac-glycero-3- phosphocholine, J Biol Chem, 270, 11612, 10.1074/jbc.270.19.11612
Patel, 2002, Perifosine, a novel alkylphospholipid, induces p21(WAF1) expression in squamous carcinoma cells through a p53-independent pathway, leading to loss in cyclin-dependent kinase activity and cell cycle arrest, Cancer Res, 62, 1401
Igal, 2010, Stearoyl-CoA desaturase-1: a novel key player in the mechanisms of cell proliferation, programmed cell death and transformation to cancer, Carcinogenesis, 31, 1509, 10.1093/carcin/bgq131
Tong, 2006, Acetyl-coenzyme A carboxylases: versatile targets for drug discovery, J Cell Biochem, 99, 1476, 10.1002/jcb.21077
De Witt Hamer, 2011, WEE1 kinase targeting combined with DNA-damaging cancer therapy catalyzes mitotic catastrophe, Clin Cancer Res, 17, 4200, 10.1158/1078-0432.CCR-10-2537
Dixon, 2002, Therapeutic exploitation of checkpoint defects in cancer cells lacking p53 function, Cell Cycle, 1, 362, 10.4161/cc.1.6.257
Whitfield, 2000, Stem-loop binding protein, the protein that binds the 3′ end of histone mRNA, is cell cycle regulated by both translational and posttranslational mechanisms, Mol Cell Biol, 20, 4188, 10.1128/MCB.20.12.4188-4198.2000
Sreekumar, 2009, Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression, Nature, 457, 910, 10.1038/nature07762
Bligh, 1959, A rapid method of total lipid extraction and purification, Can J Biochem Physiol, 37, 911, 10.1139/o59-099