Dbl family guanine nucleotide exchange factors

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Zhu, 2001, Oligomerization of DH domain is essential for Dbl-induced transformation, Mol. Cell. Biol., 21, 425, 10.1128/MCB.21.2.425-437.2001

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Gulli, 2000, Phosphorylation of the Cdc42 exchange factor Cdc24 by the PAK-like kinase Cla4 may regulate polarized growth in yeast, Mol. Cell, 6, 1155, 10.1016/S1097-2765(00)00113-1

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Zhang, 1999, Functional interaction between the cytoplasmic leucine-zpper domain of HIV-1 gp41 and p115RhoGEF, Curr. Biol., 9, 1271, 10.1016/S0960-9822(99)80511-9

Bourguignon, 2000, CD44 interaction with Tiam1 promotes Rac1 signaling and hyaluronic acid-mediated breast tumor cell migration, J. Biol. Chem., 275, 1829, 10.1074/jbc.275.3.1829

Bourguignon, 2000, Ankyrin–Tiam1 interaction promotes Rac1 signaling and metastatic breast tumor cell invasion and migration, J. Cell Biol., 150, 177, 10.1083/jcb.150.1.177

Shamah, 2001, EphA receptors regulate growth cone dynamics through the novel guanine nucleotide exchange factor ephexin, Cell, 105, 233, 10.1016/S0092-8674(01)00314-2

Manser, 1998, PAK kinases are directly coupled to the PIX family of nucleotide exchange factors, Mol. Cell, 1, 183, 10.1016/S1097-2765(00)80019-2

Bose, 2001, Assembly of scaffold-mediated complexes containing Cdc42p, the exchange factor Cdc4p, and the effector Cla4p required for cell cycle-regulated phosphorylation of Cdc42p, J. Biol. Chem., 276, 7176, 10.1074/jbc.M010546200

Cherfils, 1999, GEFs: structural basis for their activation of small GTP-binding proteins, Trends Biochem. Sci., 24, 306, 10.1016/S0968-0004(99)01429-2

Liu, 1998, NMR structure and mutagenesis of the N-terminal Dbl homology domain of the nucleotide exchange factor Trio, Cell, 95, 269, 10.1016/S0092-8674(00)81757-2

Soisson, 1998, Crystal structure of the Dbl and pleckstrin homology domains from the human son of sevenless protein, Cell, 95, 259, 10.1016/S0092-8674(00)81756-0

Aghazadeh, 1998, Structure and mutagenesis of the Dbl homology domain, Nat. Struct. Biol., 5, 1098, 10.1038/4209

Worthylake, 2000, Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1, Nature, 408, 682, 10.1038/35047014

Zhang, 2000, The role of Mg2+ cofactor in guanine nucleotide exchange and GTP hydrolysis reactions of Rho family GTPases, J. Biol. Chem., 275, 25299, 10.1074/jbc.M001027200

Gao, Y. et al. Trp56 of Rac1 specifies interaction with a subset of guanine nucleotide exchange factors. J. Biol. Chem. (in press)

Movilla, 1999, Biological and regulatory properties of Vav-3, a new member of the Vav family of oncoproteins, Mol. Cell. Biol., 19, 7870, 10.1128/MCB.19.11.7870

Hardt, 1998, S. typhimurium encodes an activator of Rho GTPases that induces membrane ruffling and nuclear responses in host cells, Cell, 93, 815, 10.1016/S0092-8674(00)81442-7

Chiang, 2001, Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10, Nature, 410, 944, 10.1038/35073608