Data fusion in metabolomic cancer diagnostics

Metabolomics - Tập 9 - Trang 3-8 - 2012
Rasmus Bro1, Hans Jørgen Nielsen2, Francesco Savorani1, Karin Kjeldahl1, Ib Jarle Christensen3, Nils Brünner4, Anders Juul Lawaetz1
1Department of Food Science, University of Copenhagen, Copenhagen, Denmark
2Department of Surgical Gastroenterology, Copenhagen University Hospital, Hvidovre, Denmark
3The Finsen Laboratory, Rigshospitalet, Copenhagen Biocenter, Copenhagen, Denmark and Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Copenhagen, Denmark
4Department of Veterinary Disease Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Tóm tắt

We have recently shown that fluorescence spectroscopy of plasma samples has promising abilities regarding early detection of colorectal cancer. In the present paper, these results were further developed by combining fluorescence with the biomarkers, CEA and TIMP-1 and traditional metabolomic measurements in the form of 1H NMR spectroscopy. The results indicate that using an extensive profile established by combining such measurements together with the biomarkers is better than using single markers.

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Metabolomics

Tập 9

3-8

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