DNA damage, mutation and fine structure DNA repair in aging

Mutation Research/DNAging - Tập 338 Số 1-6 - Trang 25-34 - 1995
Vilhelm A. Bohr1, R. Michael Anson
1Laboratory of Molecular Genetics, National Institutes on Aging, NIH, Baltimore, MD 21224, USA.

Tóm tắt

Từ khóa


Tài liệu tham khảo

Adachi, 1993, A deletion of mitochondrial DNA in murine doxorubicin-induced cardiotoxicity, Biochem. Biophys. Res. Commun., 195, 945, 10.1006/bbrc.1993.2135

Anderson, 1980, The presence of nuclear and mitochondrial uracil-DNA glycosylase in extracts of human KB cells, Nucleic Acids Res, 8, 875

Bandy, 1990, Mitochondrial mutations may increase oxidative stress: implications for carcinogenesis and aging?, Free Radical Biology and Medicine, 8, 523, 10.1016/0891-5849(90)90152-9

Bill, 1991, Loss of intragenomic DNA repair heterogeneity with cellular differentiation, J. Biol. Chem., 266, 21821, 10.1016/S0021-9258(18)54711-6

Bodenteich, 1991, A lifetime of retinal light exposure does not appear to increase initochondrial mutations, Gene, 108, 305, 10.1016/0378-1119(91)90451-G

Boerrigter, 1991, Decreased DNA repair capacity in familial but not sporadic Alzheimers disease, Neurobiol Aging., 12, 367, 10.1016/0197-4580(91)90024-E

Bohr, 1991, Gene specific DNA repair, Carcinogenesis, 12, 1983, 10.1093/carcin/12.11.1983

Bohr, 1995, DNA repair, oxidative stress, and ageing

Bradley, 1989, DNA repair deficiency for alkylation damage in cells from Alzheimers disease patients, Prog. Clin. Biol. Res., 317

Branda, 1993, Measurement of HPRT mutant frequencies in T-lymphocytes from healthy human populations, Mutat Res, 285, 10.1016/0027-5107(93)90115-V

Brossas, 1994, Multiple deletions in mitochondrial DNA are present in senescent mouse brain, Biochem. Biophys. Res. Commun., 202, 654, 10.1006/bbrc.1994.1980

Cardenas, 1993, A xenopus egg factor with DNA binding properties characteristic of terminus specific telomeric proteins, Genes and Development, 7, 883, 10.1101/gad.7.5.883

Chen, 1994, Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells, Chem. Res. Toxicol, 7, 420

Clayton, 1974, The absence of a pyrimidine dimer repair mechanism in mammalian mitochondria, 71, 2777

Cleaver, 1992, Replication of nuclear and mitochondrial DNA in X-ray-damaged cells: evidence for a nuclearspecific mechanism that down-regulates replication, Radiation Research, 131, 338, 10.2307/3578425

Cole, 1989, Measurement of mutant frequency to 6-thioguanine resistance in circulating T-lymphocytes for human population monitoring, 175

Cortopassi, 1992, A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues, 89, 7370

Danner, 1990, Alterations in Gene-Expression with Aging, 97

De Lange, 1992, Human telomeres are attached to the nuclear matrix, EMBO Journal, 717, 10.1002/j.1460-2075.1992.tb05104.x

Dileonardo, 1994, DNA Damage triggers a prolonged p53-dependent G (1) arrest and long-term induction of cip 1 in normal human fibroblasts, Genes & Development, 8, 2540, 10.1101/gad.8.21.2540

Drapkin, 1994, Dual role of TFIIH in DNA excision repair and in transcription by RNA polymerase II, Nature, 368, 769, 10.1038/368769a0

Driggers, 1993, Repair of oxidative damage within the mitochondrial DNA of RINr 38 cells, J. Biol. Chem., 268, 22042, 10.1016/S0021-9258(20)80645-0

Edris, 1994, Detection and quantitation by competitive PCR of an age-associated increase in a 4.8-KB deletion in rat mitochondrial DNA, Mutat Res, 316, 69, 10.1016/0921-8734(94)90009-4

Fraga, 1990, Oxidative damage to DNA during aging: 8-Hydroxy-2′-deoxyguanosine in rat organ DNA and urine, 87, 4533

Gadaleta, 1992, Mitochondrial DNA copy number and mitochondrial DNA deletion in adult and senescent rats, Mutat. Res., 275, 181, 10.1016/0921-8734(92)90022-H

Grist, 1992, In vivo human somatic mutation: frequency and spectrum with age, Mutat Res, 266, 189, 10.1016/0027-5107(92)90186-6

Grollman, 1993, Mutagenesis by 8-oxoguanine: an enemy within, Trends Genet, 9, 246, 10.1016/0168-9525(93)90089-Z

Gupta, 1980, Senescence of cultured human diploid fibroblasts. Are mutations responsible?, J Cell Physiol, 103, 209, 10.1002/jcp.1041030206

Harley, 1990, Telomeres shorten during aging of human fibroblasts, Nature, 345, 458, 10.1038/345458a0

Hart, 1974, 71, 2169

Hastie, 1990, Telomere reduction in human colorectal carcinoma and with aging, Nature, 346, 866, 10.1038/346866a0

Hayakawa, 1993, Age-associated damage in mitochondrial DNA in human hearts, Mol Cell Biochem, 119, 95, 10.1007/BF00926859

Holliday, 1991, A re-examination of the effects of ionizing radiation on lifespan and transformation of human diploid fibroblasts, Mutat Res, 256, 295, 10.1016/0921-8734(91)90020-C

Holliday, 1990, Evidence for allelic exclusion in chinese hamster ovary cells, The New Biologist, 2, 719

Homma, 1994, Evidence for the accumulation of oxidative stress during cellular ageing of human diploid fibroblasts, Biochem. Biophys. Res. Commun., 203, 1063, 10.1006/bbrc.1994.2290

Horn, 1984, A cloning assay for 6-thioguanine resistance provides evidence against certain somatic mutational theories of aging, J Cell Physiol., 121, 309, 10.1002/jcp.1041210207

Islas, 1995, DNA Repair in the c-myc and fms protooncogenes in UV irradiated human HL60 promyelocytic cells during differentiation, Cancer Res., 55, 336

Jones, 1989, Decreased DNA Repair in familial Alzheimers disease, Mutat Res, 219, 247, 10.1016/0921-8734(89)90007-6

Kantor, 1978, A study of the effect of ultraviolet light on the division potential of human diploid fibroblasts, Exp. Cell Res., 113, 283, 10.1016/0014-4827(78)90368-3

Kim, 1994, Specific association of human telomerase activity with immortal cells and cancer, Science, 266, 2011, 10.1126/science.7605428

Kinsella, 1987, Alzheimers disease fibroblasts have normal repair of N-methyl-N′-nitro-N-nitroso-guanidine-induced DNA damage determined by the alkaline elution technique, Biochem. Biophys. Res. Commun., 149, 355, 10.1016/0006-291X(87)90374-3

Kirkwood, 1989, DNA, Mutations and Aging, Mutat Res, 219, 1, 10.1016/0921-8734(89)90035-0

Kruk, 1995, DNA damage and repair in telomeres: Relation to aging, 92, 258

LeDoux, 1992, Repair of mitochondrial DNA after various types of DNA damage in Chinese hamster ovary cells, Carcinogenesis, 13, 1967, 10.1093/carcin/13.11.1967

LeDoux, 1993, Repair of N-methylpurines in the mitochondrial DNA of xeroderma pigmentosum complementation group D cells, Carcinogenesis, 14, 913, 10.1093/carcin/14.5.913

LeDoux, 1993, Mitochondrial DNA repair and cell injury, 461

Lee, 1993, Multiple mitochondrial DNA deletions associated with age in skeletal muscle of rhesus monkeys, Journal of Gerontology, 48, B201, 10.1093/geronj/48.6.B201

Li, 1995, Radiation-induced irreversible G(0) G(1) block is abolished in human diploid fibroblasts transfected with the human papilloma virus E6 gene-implication of the p53-cipl wafl pathway, International Journal of Oncology, 6, 233

Li, 1985, Deficient repair of DNA lesions in Alzheimers disease fibroblasts, Biochem. Biophys. Res. Commun., 129, 733, 10.1016/0006-291X(85)91953-9

Link, 1995, Gene specific DNA repair of damage induced in familial Alzheimer disease cells by ultraviolet irradiation or by nitrogen mustard, Mutat Res, 10.1016/0921-8777(94)00051-7

Liu, 1994, BCL2 translocation frequency rises with age in humans, 91, 8910

Mecocci, 1993, Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain, Ann. Neurol., 34, 609, 10.1002/ana.410340416

Mellon, 1987, Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene, Cell, 51, 241, 10.1016/0092-8674(87)90151-6

Mellon, 1989, Induction of E. Coli lactose operon selectively increases repair of its transcribed strand, Nature, 342, 95, 10.1038/342095a0

Meyne, 1989, Conservation of the human telomere sequence (TTAGGG) n among vertebrates, 86, 7049

Monnat, 1985, Nucleotide sequence preservation of human mitochondrial DNA, 82, 2895

Morley, 1982, Human lymphocytes resistant to 6-thioguanine increase with age, Mech. Ageing Dev., 19, 21, 10.1016/0047-6374(82)90046-X

Mullaart, 1990, DNA damage metabolism and aging, Mutat. Res., 237, 189, 10.1016/0921-8734(90)90001-8

Munscher, 1993, The point mutation of mitochondrial DNA characteristic for MERRF disease is found also in healthy people of different ages, FEBS Lett., 317, 27, 10.1016/0014-5793(93)81484-H

Nagasawa, 1985, Effects of X-irradiation on cell-cycle progression, induction of chromosomal aberrations and cell killing in ataxia (AT) fibroblasts, Mutat Res, 148, 71, 10.1016/0027-5107(85)90209-X

Nagasawa, 1983, Comparison of kinetics of X-ray-induced cell killing in normal, ataxia telangiectasia and hereditary retinoblastoma fibroblasts, Mutat Res, 109, 297, 10.1016/0027-5107(83)90054-4

Niggli, 1989, Mitomycin C-induced postmitotic fibroblasts retain the capacity to repair pyrimidine photodimers formed after UV-irradiation, Mutat Res, 219, 231, 10.1016/0921-8734(89)90005-2

Noda, 1994, Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen, Exp. Cell Res., 211, 90, 10.1006/excr.1994.1063

Pettepher, 1991, Repair of alkali-labile sites within the mitochondrial DNA of Rinr38 cells after exposure to the nitrosurea streptozotocin, J. Biol. Chem., 266, 3113, 10.1016/S0021-9258(18)49961-9

Pirsel, 1993, Methyl methanesulfonate adduct formation and repair in the DHFR gene and in mitochondrial DNA in hamster cells, Carcinogenesis, 14, 2105, 10.1093/carcin/14.10.2105

Purmal, 1994, Major oxidative products of cytosine, 5-hydroxycytosine and 5-hy-droxyuracil, exhibit sequence context-dependent mispairing in vitro, Nucleic Acids Res., 22, 72, 10.1093/nar/22.1.72

Rattan, 1989, DNA damage and repair during cellular aging, Int. Review of Cytology, 116, 47, 10.1016/S0074-7696(08)60638-5

Richter, 1992, Reactive oxygen and DNA damage in mitochondria, Mutat Res, 275, 249, 10.1016/0921-8734(92)90029-O

Richter, 1988, Normal oxidative damage to mitochondrial and nuclear DNA is extensive, 85, 6465

Robhins, 1974, Xeroderma pigmentosum: An inherited disease with sun sensitivity, multiple cutaneous neoplasms, and abnormal DNA repair, Ann. Int. Med., 80, 221, 10.7326/0003-4819-80-2-221

Robbins, 1985, Parkinsons disease and Alzheimers disease, J. Neurol. Neurosurg. Psych., 48, 916, 10.1136/jnnp.48.9.916

Robison, 1987, Alzheimers disease cells exhibit defective repair of alkylating agent induced DNA damage, Ann. Neurol., 21, 250, 10.1002/ana.410210306

Rodemann, 1989, Selective enrichment and biochemical characterization of seven human skin fibroblasts cell types in vitro, Exp. Cell Res., 180, 84, 10.1016/0014-4827(89)90214-0

Scudiero, 1981, Hypersensitivity to N-methyl-N′-nitro-N-nitroso-guanidine in fibroblasts from patients with Huntington disease, familial dysautonomia and other primary neuronal degenerations, 78, 6451

Scudiero, 1986, Alzheimers disease fibroblasts are hypersensitive to the lethal effects of DNA damaging chemicals, Mutat Res, 159, 125, 10.1016/0027-5107(86)90121-1

Shigenaga, 1994, Oxidative damage and mitochondrial decay in aging, 91, 10771

Slagboom, 1992, The dynamics of genomeorganization and expression during the aging process, Ann. N.Y. Acad. Sci., 673, 58, 10.1111/j.1749-6632.1992.tb27437.x

Snyderwine, 1992, Gene- and strand-specific damage and repair in Chinese Hamster Ovary cell treated with 4-nitroquinoline 1-oxide, Cancer Research., 52, 4183

Sohal, 1994, Oxidative damage, mitoehondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse, Mechanisms of Ageing and Development, 74, 121, 10.1016/0047-6374(94)90104-X

Stevenson, 1981, Senescence in vitro and ionising radiations-the human diploid fibroblast model, Mechanisms of Ageing and Development, 15, 51, 10.1016/0047-6374(81)90007-5

Szilard, 1959, On the nature of the aging process, 45, 30

Thompson, 1994, Specific repression of the yeast silent mating locus HMR by an adjacent telomere, Mol Cell Biol, 14, 446, 10.1128/MCB.14.1.446

Tice, 1985, DNA repair and replication in aging organisms and cells, 173

Tobi, 1993, Alkylation damage and repair in Alzheimer's disease lymphocytes, Gerontology, 39, 241, 10.1159/000213539

Tobi, 1993, DNA double strand breaks measured by pulsed field gel electrophoresis in irradiated lymphocytes from normal humans and those with Alzheimer's disease, Int. J. Radiat. Biol., 63, 617, 10.1080/09553009314450801

Tomkinson, 1988, Mitochondrial endonuclease activities for apurinic/apyrimidinic sites in DNA from mouse cells, J. Biol. Chem., 263, 12532, 10.1016/S0021-9258(18)37787-1

Tornaletti, 1994, Slow repair of pyrimidine dimers at p53-mutation hotspots in skin cancer, Science, 263, 1436, 10.1126/science.8128225

Trainor, 1984, Mutation frequency in human lymphocytes increases with age, Mech. Ageing Dev., 27, 83, 10.1016/0047-6374(84)90084-8

Venema, 1990, The genetic defect in Cockayne syndrome is associated with a defect in repair of UV-induced DNA damage in transcriptionally active DNA, 87, 4707

Wang, 1991, Reduced DNA repair in progeria cells and effects of gamma ray irradiation on UV-induced unscheduled DNA synthesis in normal and progeria cells, Mutat Res, 256, 59, 10.1016/0921-8734(91)90034-9

Wei, 1993, DNA repair and aging in basal cell carcinoma: A molecular epidemiology study, 90, 1614

Williams, 1981, DNA damage and repair in aging mammals, 25

Wright, 1992, The two stage mechanism controlling cellular senescence and immortalization, Experimental Gerontology, 27, 383, 10.1016/0531-5565(92)90069-C

Yu, 1991, Developmentally programmed healing of chromosomes by telomerase in tetrahymena, Cell, 67, 823, 10.1016/0092-8674(91)90077-C

Zhang, 1993, Occurrence of a particular base substitution (3243 A to G) in mitochondrial DNA of tissues of ageing humans, Biochem. Biophys. Res. Commun., 195, 1104, 10.1006/bbrc.1993.2158