DNA-based vaccines for the treatment of cancer – an experimental model

Shigemasa, 2000, Induction of matrix metalloprotease-7 is common in mucinous ovarian tumors including early stage disease, Med. Oncol., 17, 52, 10.1007/BF02826217 Folkman, 2000, Incipient angiogenesis, J. Natl. Cancer Inst., 92, 94, 10.1093/jnci/92.2.94 Hahnfeldt, 1999, Tumor development under angiogenic signaling: a dynamical theory of tumor growth, treatment response, and postvascular dormancy, Cancer Res., 59, 4770 Kolchinsky, 1997, Drug resistance conferred by MDR1 expression in spheroids formed by glioblastoma cell lines, Anticancer Res., 17, 3321 Bronner, 1994, Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer, Nature, 368, 258, 10.1038/368258a0 Prehn, 1957, Immunity to methylcholanthrene-induced sarcomas, J. Natl. Cancer Inst., 18, 769 Van Pel, 1982, Protection against a nonimmunogenic mouse leukemia by an immunogenic variant obtained by mutagenesis, Proc. Natl. Acad. Sci. USA, 79, 4718, 10.1073/pnas.79.15.4718 Gilewski, 2000, Vaccination of high-risk breast cancer patients with mucin-1 (MUC1) keyhole limpet hemocyanin conjugate plus QS-21, Clin. Cancer Res., 6, 1670 Disis, 2000, Delayed-type hypersensitivity response is predictor of peripheral blood T-cell immunity after HER2/neu peptide immunization, Clin. Cancer Res., 6, 1347 Minchell, 2000, Naked DNA and adenoviral immunizations for immunotherapy of prostate cancer: a Phase I/II clinical trial, Eur. Urol., 38, 208, 10.1159/000020281 Bhattachary-Chatterjee, 2000, Counterpoint. Cancer vaccines: single-epitope versus multiple-epitope antigen vaccine, Cancer Immunol. Immunother., 49, 133, 10.1007/s002620050612 Cavallo, 1993, Protective and curative potential of vaccination with interleukin-2-gene-transfected cells from a spontaneous mouse mammary adenocarcinoma, Cancer Res., 53, 5067 Nabel, 1996, Immune response in human melanoma after transfer of an allogeneic class I major histocompatibility complex gene with DNA-liposome complexes, Proc. Natl. Acad. Sci. USA, 93, 15388, 10.1073/pnas.93.26.15388 Gilboa, 1998, Immunotherapy of cancer with dendritic cell-based vaccines, Cancer Immunol. Immunother., 46, 82, 10.1007/s002620050465 Cohen, 1994, Neoplastic cells that express low levels of MHC class I determinants escape host immunity, Semin. Cancer Biol., 5, 419 Gong, 1997, Induction of antitumor activity by immunization with fusions of dendritic and carcinoma cells, Nat. Med., 3, 558, 10.1038/nm0597-558 Liang, 1975, Resistance to murine leukemia in mice rejecting syngeneic somatic hybrid cells, J. Immunol., 116, 623, 10.4049/jimmunol.116.3.623 Liang, 1977, Resistance to murine leukemia in mice receiving simultaneous injections of syngeneic hybrid and parental neoplastic cells, J. Immunol., 118, 903, 10.4049/jimmunol.118.3.903 de Zoeten, 1998, Resistance to melanoma in mice immunized with semi-allogeneic fibroblasts transfected with genomic DNA from melanoma cells, J. Immunol., 160, 2915, 10.4049/jimmunol.160.6.2915 de Zoeten, 1999, Immunity to breast cancer in mice immunized with semi-allogeneic fibroblasts transfected with DNA from breast cancer cells, J. Immunol., 162, 6934, 10.4049/jimmunol.162.11.6934