DNA adducts derived from administration of acrylamide and glycidamide to mice and rats

LoPachin, 2003, Acrylamide axonopathy revisited, Toxicol. Appl. Pharmacol., 188, 135, 10.1016/S0041-008X(02)00072-8

Calleman, 1994, Relationships between biomarkers of exposure and neurological effects in a group of workers exposed to acrylamide, Toxicol. Appl. Pharmacol., 126, 361, 10.1006/taap.1994.1127

IARC, Acrylamide, IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, vol. 60, Some Industrial Chemicals, International Agency for Research on Cancer, IARC Press, Lyon, France, 1994, pp. 389–433.

Dearfield, 1995, Acrylamide: a review of its genotoxicity and an assessment of heritable genetic risk, Mutat. Res., 330, 71, 10.1016/0027-5107(95)00037-J

Johnson, 1986, Chronic toxicity and oncogenicity study on acrylamide incorporated in the drinking water of Fischer 344 rats, Toxicol. Appl. Pharmacol., 85, 154, 10.1016/0041-008X(86)90109-2

Friedman, 1995, A lifetime oncogenicity study in rats with acrylamide, Fundam. Appl. Toxicol., 27, 95, 10.1006/faat.1995.1112

Bergmark, 1997, Hemoglobin adducts of acrylamide and acrylonitrile in laboratory workers, smokers, and nonsmokers, Chem. Res. Toxicol., 10, 78, 10.1021/tx960113p

Tareke, 2002, Analysis of acrylamide, a carcinogen formed in heated foodstuffs, J. Agric. Food Chem., 50, 4998, 10.1021/jf020302f

Sumner, 1999, Role of cytochrome P4502E1 in the metabolism of acrylamide and acrylonitrile in mice, Chem. Res. Toxicol., 12, 1110, 10.1021/tx990040k

Solomon, 1985, Direct alkylation of 2′-deoxynucleosides and DNA following in vitro reaction with acrylamide, Cancer Res., 45, 3465

Solomon, 1999, Cyclic adducts and intermediates induced by simple epoxides, IARC Sci. Publ., 150, 123

Bergmark, 1991, Formation of hemoglobin adducts of acrylamide and its epoxide metabolite glycidamide in the rat, Toxicol. Appl. Pharmacol., 111, 352, 10.1016/0041-008X(91)90036-E

Sumner, 1992, Characterization and quantitation of urinary metabolites of [1,2,3-13C]acrylamide in rats and mice using 13C nuclear magnetic resonance spectroscopy, Chem. Res. Toxicol., 5, 81, 10.1021/tx00025a014

Twaddle, 2004, Determination of acrylamide and glycidamide serum toxicokinetics in B6C3F1 mice using LC-ES/MS/MS, Cancer Lett., 207, 9, 10.1016/j.canlet.2003.10.017

D.R. Doerge, J.F. Young, L.P. McDaniel, N.C. Twaddle, M.I. Churchwell, Toxicokinetics of acrylamide and glycidamide in B6C3F1 mice, Toxicol. Appl. Pharmacol., in press.

Bergmark, 1993, Determination of hemoglobin adducts in humans occupationally exposed to acrylamide, Toxicol. Appl. Pharmacol., 120, 45, 10.1006/taap.1993.1085

Licea Perez, 1999, Simultaneous analysis of hemoglobin adducts of acrylamide and glycidamide by gas chromatography–mass spectrometry, Anal. Biochem., 274, 59, 10.1006/abio.1999.4267

Vesper, 2004, Pilot study on the impact of potato chips consumption on biomarkers of acrylamide exposure, Am. Chem. Soc. Spring Meet. Abstr.

Paulsson, 2002, Hemoglobin adducts and micronucleus frequencies in mouse and rat after acrylamide or N-methylolacrylamide treatment, Mutat. Res., 516, 101, 10.1016/S1383-5718(02)00027-X

Generoso, 1996, Dominant lethal mutations, heritable translocations, and unscheduled DNA synthesis induced in male mouse germ cells by glycidamide, a metabolite of acrylamide, Mutat. Res., 371, 175, 10.1016/S0165-1218(96)90106-8

Adler, 2000, 1-Aminobenzotriazole inhibits acrylamide-induced dominant lethal effects in spermatids of male mice, Mutagenesis, 15, 133, 10.1093/mutage/15.2.133

Hashimoto, 1985, Mutagenicity of acrylamide and its analogues in Salmonella typhimurium, Mutat. Res., 158, 129, 10.1016/0165-1218(85)90075-8

Besaratinia, 2004, Genotoxicity of acrylamide and glycidamide, J. Nat. Cancer Inst., 96, 1023, 10.1093/jnci/djh186

Bucher, 1990, Neurotoxicity and carcinogenicity of N-methylolacrylamide in F344 rats and B6C3F1 mice, J. Toxicol. Environ. Health, 31, 161, 10.1080/15287399009531446

Segerbäck, 1995, Formation of N-7-(2-carbamoyl-2-hydroxyethyl)guanine in DNA of the mouse and the rat following intraperitoneal administration of [14C]acrylamide, Carcinogenesis, 16, 1161, 10.1093/carcin/16.5.1161

Gamboa da Costa, 2003, DNA adduct formation from acrylamide via conversion to glycidamide in adult and neonatal mice, Chem. Res. Toxicol., 16, 1328, 10.1021/tx034108e

Twaddle, 2004, Autoclave sterilization produces acrylamide in rodent diets: implications for toxicity testing, J. Agric. Food Chem., 52, 4344, 10.1021/jf0497657

Park, 2002, Acrylamide-induced cellular transformation, Toxicol. Sci., 65, 177, 10.1093/toxsci/65.2.177

Manière, 2004, DNA damage and DNA adduct formation in rat tissues following oral administration of acrylamide, Mutat. Res.

Segerbäck, 1998, Tissue distribution of DNA adducts in male Fischer rats exposed to 500ppm of propylene oxide: quantitative analysis of 7-(2-hydroxypropyl)guanine by 32P-postlabeling, Chem. Biol. Interact., 115, 229, 10.1016/S0009-2797(98)00076-3

Walker, 1992, Molecular dosimetry of ethylene oxide: formation and persistence of 7-(2-hydroxyethyl)guanine in DNA following repeated exposures of rats and mice, Cancer Res., 52, 4328

Koskinen, 2000, Specific DNA adducts induced by some mono-substituted epoxides in vitro and in vivo, Chem. Biol. Interact., 129, 209, 10.1016/S0009-2797(00)00206-4

Loeb, 1986, Mutagenesis by apurinic/apyrimidinic sites, Ann. Rev. Genet., 20, 201, 10.1146/annurev.ge.20.120186.001221

Engelward, 1998, A chemical and genetic approach together define the biological consequences of 3-methyladenine lesions in the mammalian genome, J. Biol. Chem., 273, 5412, 10.1074/jbc.273.9.5412

Manjanatha, 2004, Evaluation of mutagenicity in Big Blue (BB) mice administered acrylamide (AA) and glycidamide (GA) in drinking water for 4 weeks, Environ. Mol. Mutagen., 44, 214