DNA Damage Response Proteins and Oxygen Modulate Prostaglandin E2 Growth Factor Release in Response to Low and High LET Ionizing Radiation

Chris Allen1, Walter Tinganelli2,3, Neelam Sharma1, Jingyi Nie1, Cory Sicard1, Francesco Natale2, Maurice King1, Steven B. Keysar4, Antonio Jimeno4, Yoshiya Furusawa5,3, Ryuichi Okayasu6, Akira Fujimori6, Marco Durante2, Jac A. Nickoloff1
1Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, USA
2GSI Helmholtzzentrum für Schwerionenforschung GmbH, Darmstadt, Germany
3Research Development and Support Center, National Institute of Radiological Sciences, Chiba, Japan
4Division of Medical Oncology, University of Colorado School of Medicine, Aurora, CO, USA
5Research Center for Radiation Protection, National Institute of Radiological Sciences, Chiba, Japan
6Research Center for Charged Particle Therapy, National Institute of Radiological Sciences, Chiba, Japan

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