Cytotoxic T Lymphocytes Regenerated from iPS Cells Have Therapeutic Efficacy in a Patient-Derived Xenograft Solid Tumor Model

iScience - Tập 23 - Trang 100998 - 2020
Soki Kashima1,2,3, Takuya Maeda1, Kyoko Masuda1, Seiji Nagano1, Takamitsu Inoue2, Masashi Takeda3, Yuka Kono1,3, Takashi Kobayashi3, Shigeyoshi Saito4, Takahiro Higuchi5, Hiroshi Ichise1, Yuka Kobayashi1, Keiko Iwaisako6, Koji Terada7, Yasutoshi Agata7, Kazuyuki Numakura2, Mitsuru Saito2, Shintaro Narita2, Masaki Yasukawa8, Osamu Ogawa3
1Laboratory of Immunology, Institute for Frontier Life and Medical Sciences, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan
2Department of Urology, Akita University Graduate School of Medicine, Akita, Japan
3Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, Japan
4Department of Medical Physics and Engineering, Division of Health Sciences, Osaka University, Osaka, Japan
5Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, Osaka, Japan
6Department of Medical Life Systems, Faculty of Life and Medical Sciences, Doshisha University, Kyoto, Japan
7Department of Biochemistry and Molecular Biology, Shiga University of Medical School, Shiga, Japan
8Department of Hematology, Clinical Immunology and Infectious Diseases, Graduate School of Medicine, Ehime University, Matsuyama, Ehime, Japan

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