Cytomegalovirus encephalitis: diagnosis with clinical approach, EEG and PCR techniques

Springer Science and Business Media LLC - Tập 20 - Trang 255-258 - 1999
M. Maschio1, F. Giudiceandrea2, P. Contadini3, B. Jandolo4
1Section of Neurology, A. Angelucci Hospital, I-00028 Subiaco (Roma), Italy, , IT
2Department of Surgery, University of Rome Tor Vergata, Roma, Italy, , FR
3Intensive Care Unit, A. Angelucci Hospital, Subiaco (Roma), Italy, , IT
4Department of Neurology, Regina Elena National Oncological Institute, Roma, Italy, , IT

Tóm tắt

Cytomegalovirus (CMV) encephalitis is particularly evident in immunodepressed patients. Often diagnosis is difficult and time-consuming because of the complex basic clinical picture of these patients. We describe the diagnostic steps taken in a case of cytomegalovirus encephalitis affecting an elderly patient, classified as immunodepressed and deceased on the thirty-fifth day of hospitalisation in the intensive care unit due to acute myocardial infarction. Treatment with ganciclovir, 30 mg/kg per day, begun at the time of diagnosis, appears to have had a positive effect on the neurologic symptoms.