Cytokine mRNA expression in inflammatory multiple sclerosis lesions: Detection by non-radioactive in situ hybridization

Woodroofe, 1986, Immunocytochemical characterisation of the immune reaction in the Central Nervous System in Multiple Sclerosis, J Neurol Sci, 74, 135, 10.1016/0022-510X(86)90100-0

Esiri, 1987, Macrophage populations associated with multiple sclerosis plaques, Neuropathol & Appl Neurobiol, 13, 451, 10.1111/j.1365-2990.1987.tb00074.x

Frei, 1991, Interleukin-6 is elevated in plasma in multiple sclerosis, J Neuroimmunol, 31, 147, 10.1016/0165-5728(91)90020-8

Gallo, 1991, A longitudinal study on IL-2, sIL-2R, IL-4 and IFN-γ in multiple sclerosis CSF and serum, J Neurol Sci, 101, 227, 10.1016/0022-510X(91)90050-H

Hauser, 1990, Cytokine accumulations in CSF of multiple sclerosis patients: frequent detection of interleukin-1 and tumor necrosis factor but not interleukin-6, Neurology, 40, 1735, 10.1212/WNL.40.11.1735

Peter, 1991, Serum and CSF levels of IL-2, sIL-2R, TNF-α, and IL-1β in chronic progressive multiple sclerosis: expected lack of clinical utility, Neurology, 41, 121, 10.1212/WNL.41.1.121

Maimone, 1991, Cytokine levels in the cerebrospinal fluid and serum of patients with multiple sclerosis, J Neuroimmunol, 32, 67, 10.1016/0165-5728(91)90073-G

Franiciotta, 1989, Tumour necrosis factor in serum and cerebrospinal fluid of patients with multiple sclerosis, Ann Neurol, 26, 787, 10.1002/ana.410260618

Tsukada, 1991, Tumor necrosis factor and interleukin-1 in the CSF and sera of patients with multiple sclerosis, J Neurol Sci, 102, 230, 10.1016/0022-510X(91)90315-X

Sharief, 1991, Association between tumor necrosis factor-α and disease progression in patients with multiple sclerosis, N Engl J Med, 325, 467, 10.1056/NEJM199108153250704

Hofman, 1989, Tumor necrosis factor identified in multiple sclerosis brain, J Exp Med, 170, 607, 10.1084/jem.170.2.607

Selmaj, 1991, Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions, J Clin Invest, 87, 949, 10.1172/JCI115102

Harrison PJ, Pearson RCA (1990) In situ hybridisation histochemistry and the study of gene expression in human brain

Selmaj, 1988, Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro, Ann Neurol, 23, 339, 10.1002/ana.410230405

Merrill, 1989, In vitro study of mediators of inflammation in multiple sclerosis, J Clin Immunol, 9, 84, 10.1007/BF00916935

Philip, 1986, Tumor necrosis factor as immunomodulator and mediator of monocyte cytotoxicity induced by itself, gamma-interferon and interleukin-1, Nature, 323, 86, 10.1038/323086a0

Loughlin, 1992, Regulation of Fc receptor and major histocompatibility complex antigen expression on isolated rat microglia by tumour necrosis factor, interleukin-1 and lipopolysaccharide: effects on interferon-gamma induced activation, Immunology, 75, 170

Parekh, 1992, Glycosylation of interleukin-6 purified from normal human blood mononuclear cells, Eur J Biochem, 203, 135, 10.1111/j.1432-1033.1992.tb19838.x

Van Damme, 1987, Identification of the human 26-KD protein, interferon β2 (IFN-β2) as a B cell hybridoma plasmacytoma growth factor induced by interleukin-1 and tumour necrosis factor, J Exp Med, 165, 914, 10.1084/jem.165.3.914

Loughlin, 1993, Modulation of interferon-gamma induced MHC class II and Fc receptor expression on isolated microglia by transforming growth factor β1, interleukin-4 noradrenaline and glucocorticoids, Immunol, 79, 125

Kennedy, 1992, Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery, J Immunol, 149, 2496

Woodroofe, 1991, Detection of interleukin-1 and interleukin-6 in adult rat brain, following mechanical injury, by in vivo microdialysis: evidence of a role for microglia in cytokine production, J Neuroimmunol, 33, 227, 10.1016/0165-5728(91)90110-S

Yamamura, 1991, Defining protective responses to pathogens: cytokine profiles in leprosy lesions, Science, 254, 277, 10.1126/science.1925582