Cytokine-Induced Sickness Behavior: Where Do We Stand?

Anisman, 1999, Anhedonic and anxiogenic effects of cytokine exposure, Adv. Exp. Med. Biol., 461, 199, 10.1007/978-0-585-37970-8_12

Appels, 1999, Inflammation and the mental state before an acute coronary event, Ann. Med., 31, 41, 10.1080/07853890.1999.11904398

Aubert, 1995, Compared effects of cold ambient temperature and cytokines on macronutrient intake in rats, Physiol. Behav., 57, 869, 10.1016/0031-9384(94)00391-H

Aubert, 1997, Differential effects of lipopolysaccharide on pup retrieving and nest building in lactating mice, Brain Behav. Immun., 11, 107, 10.1006/brbi.1997.0485

Aubert, 1997, Differential effect of lipopolysaccharide on food hoarding behavior and food consumption in rats, Brain Behav. Immun., 11, 229, 10.1006/brbi.1997.0503

Aubert, 1995, Pyrogens specifically disrupt the acquisition of a task involving cognitive processing in the rat, Brain Behav. Immun., 9, 129, 10.1006/brbi.1995.1013

Bluthe, 1992, Effects of interleukin-1 receptor antagonist on the behavioral effects of lipopolysaccharide in rat, Brain Res., 573, 318, 10.1016/0006-8993(92)90779-9

Bluthe, 1996, Vagotomy attenuates behavioural effects of interleukin-1 injected peripherally but not centrally, NeuroReport, 7, 1485, 10.1097/00001756-199606170-00008

Bluthe, 1994, Synergy between tumor necrosis factor alpha and interleukin-1 in the induction of sickness behavior in mice, Psychoneuroendocrinology, 19, 197, 10.1016/0306-4530(94)90009-4

Bluthe, 1994, Lipopolysaccharide induces sickness behaviour in rats by a vagal mediated mechanism, C. R. Acad. Sci. III, 317, 499

Bolles, 1974, Cognition and motivation: Some historical trends, 1

Bull, 1991, Modulation of body temperature through taste aversion conditioning, Physiol. Behav., 49, 1229, 10.1016/0031-9384(91)90356-S

Bull, 1994, Acute-phase immune response: lipopolysaccharide-induced fever and sleep alterations are not simultaneously conditionable in the rat during the inactive (light) phase, Physiol. Behav., 56, 143, 10.1016/0031-9384(94)90272-0

Cao, 1997, Involvement of cyclooxygenase-2 in LPS-induced fever and regulation of its mRNA by LPS in the rat brain, Am. J. Physiol., 272, R1712

Capuron, 1999, Prediction of the depressive effects of interferon alfa therapy by the patient's initial affective state, N. Engl. J. Med., 340, 1370, 10.1056/NEJM199904293401716

Capuron, 2000, Early depressive symptoms in cancer patients receiving interleukin 2 and/or interferon alpha-2b therapy, J. Clin. Oncol., 18, 2143, 10.1200/JCO.2000.18.10.2143

Castanon, 2001, Chronic treatment with the atypical antidepressant tianeptine attenuates sickness behavior induced by peripheral but not central lipoplysaccharide and interleukin-1β in the rat, Psychopharmacology, 10.1007/s002130000595

Castanon, N, Konsman, J. P, Médina, C, Chauvet, N, &, Dantzer, R. Chronic treatment with the atypical antidepressant tianeptine attenuates lipopolysaccharide-induced Fos expression in the rat paraventricular nucleus and corticosterone secretion, (, in preparation, ).

Dantzer, 2001, Cytokine effects on behavior, 703

Dantzer, 2000, Neural and humoral pathways of communication from the immune system to the brain: parallel or convergent?, Autonom. Neurosci., 85, 60, 10.1016/S1566-0702(00)00220-4

Dantzer, 1999, Cytokines, stress, and depression: Conclusions and perspectives, Adv. Exp. Med. Biol., 461, 317, 10.1007/978-0-585-37970-8_17

Denicoff, 1989, The neuroendocrine effects of interleukin-2 treatment, J. Clin. Endocrinol. Metab., 69, 402, 10.1210/jcem-69-2-402

Ericsson, 1994, A functional anatomical analysis of central pathways subserving the effects of interleukin-1 on stress-related neuroendocrine neurons, J. Neurosci., 14, 897, 10.1523/JNEUROSCI.14-02-00897.1994

Exton, 1995, Behavioral conditioning of lipopolysaccharide-induced anorexia, Physiol. Behav., 57, 401, 10.1016/0031-9384(94)00249-5

Exton, 1995, Modification of body temperature and sleep state using behavioral conditioning, Physiol. Behav., 57, 723, 10.1016/0031-9384(94)00314-9

Gatti, 1993, Induction of tumor necrosis factor-alpha mRNA in the brain after peripheral endotoxin treatment: Comparison with interleukin-1 family and interleukin-6, Brain Res., 624, 291, 10.1016/0006-8993(93)90090-A

Gibertini, 1995, Spatial learning impairment in mice infected with Legionella pneumophila or administered exogenous interleukin-1-beta, Brain. Behav. Immun., 9, 113, 10.1006/brbi.1995.1012

Goehler, 1999, Interleukin-1beta in immune cells of the abdominal vagus nerve: A link between the immune and nervous systems?, J. Neurosci., 19, 2799, 10.1523/JNEUROSCI.19-07-02799.1999

Goujon, 1995, Stress downregulates lipopolysaccharide-induced expression of proinflammatory cytokines in the spleen, pituitary, and brain of mice, Brain. Behav. Immun., 9, 292, 10.1006/brbi.1995.1028

Grunfeld, 1996, Regulation of lipid metabolism by cytokines during host defense, Nutrition, 12, S24

Hansen, 1998, Vagotomy blocks the induction of interleukin-1beta (IL-1beta) mRNA in the brain of rats in response to systemic IL-1beta, J. Neurosci., 18, 2247, 10.1523/JNEUROSCI.18-06-02247.1998

Hare, 1995, Bacterial lipopolysaccharide-induced changes in FOS protein expression in the rat brain: Correlation with thermoregulatory changes and plasma corticosterone, J. Neuroendocrinol., 7, 791, 10.1111/j.1365-2826.1995.tb00716.x

Hart, 1988, Biological basis of the behavior of sick animals, Neurosci. Biobehav. Rev., 12, 123, 10.1016/S0149-7634(88)80004-6

Hiramoto, 1991, Conditioning the elevation of body temperature, a host defensive reflex response, Life Sci., 49, 93, 10.1016/0024-3205(91)90022-4

Janz, 1996, Pavlovian conditioning of LPS-induced responses: Effects on corticosterone, splenic NE, and IL-2 production, Physiol. Behav., 59, 1103, 10.1016/0031-9384(95)02171-X

Kelley, 2001, It's time for psychoneuroimmunology, Brain Behav. Immun., 10.1006/brbi.2000.0608

Kent, 1992, Different receptor mechanisms mediate the pyrogenic and behavioral effects of interleukin 1, Proc. Natl. Acad. Sci. USA, 89, 9117, 10.1073/pnas.89.19.9117

Kent, 1992, Sickness behavior as a new target for drug development, Trends Pharmacol. Sci., 13, 24, 10.1016/0165-6147(92)90012-U

Kent, 1996, Mechanisms of sickness-induced decreases in food-motivated behavior, Neurosci. Biobehav. Rev., 20, 171, 10.1016/0149-7634(95)00037-F

Kluger, 1991, Fever: Role of pyrogens and cryogens, Physiol. Rev., 71, 93, 10.1152/physrev.1991.71.1.93

Konsman, J. P. 2000, Immune-to-brain communication. A functional neuroanatomy analysis. Unpublished PhD thesis, University of Groningen, Groningen, The Netherlands.

Konsman, 1999, Temporal and spatial relationships between lipopolysaccharide-induced expression of Fos, interleukin-1beta and inducible nitric oxide synthase in rat brain, Neuroscience, 89, 535, 10.1016/S0306-4522(98)00368-6

Laye, 1995, Subdiaphragmatic vagotomy blocks induction of IL-1 beta mRNA in mice brain in response to peripheral LPS, Am. J. Physiol., 268, R1327

Laye, 1994, Peripheral administration of lipopolysaccharide induces the expression of cytokine transcripts in the brain and pituitary of mice, Brain Res. Mol. Brain Res., 27, 157, 10.1016/0169-328X(94)90197-X

Maes, 1995, The monocyte-T-lymphocyte hypothesis of major depression [editorial], Psychoneuroendocrinology, 20, 111, 10.1016/0306-4530(94)00066-J

Maier, 1995, Intracerebroventricular interleukin-1 receptor antagonist blocks the enhancement of fear conditioning and interference with escape produced by inescapable shock, Brain Res., 695, 279, 10.1016/0006-8993(95)00930-O

Mascarucci, 1998, Glutamate release in the nucleus tractus solitarius induced by peripheral lipopolysaccharide and interleukin-1 beta, Neuroscience, 86, 1285, 10.1016/S0306-4522(98)00105-5

Meyers, 1999, Mood and cognitive disorders in cancer patients receiving cytokine therapy, Adv. Exp. Med. Biol., 461, 75, 10.1007/978-0-585-37970-8_5

Miller, 1999, Effects of cytokines on glucocorticoid receptor expression and function. Glucocorticoid resistance and relevance to depression, Adv. Exp. Med. Biol., 461, 107, 10.1007/978-0-585-37970-8_7

Miller, 1964, Some psychophysiological studies of motivation and of the behavioral effects of illness, Bull. Br. Psychol. Soc., 17, 1

Oitzl, 1993, Interleukin-1 beta, but not interleukin-6, impairs spatial navigation learning, Brain Res., 613, 160, 10.1016/0006-8993(93)90468-3

Plata-Salaman, 1999, 1998 Curt P. Richter Award. Brain mechanisms in cytokine-induced anorexia, Psychoneuroendocrinology, 24, 25

Ross, 1999, Atherosclerosis is an inflammatory disease, Am. Heart J., 138, S419, 10.1016/S0002-8703(99)70266-8

Sagar, 1995, Anatomic patterns of Fos immunostaining in rat brain following systemic endotoxin administration, Brain Res. Bull., 36, 381, 10.1016/0361-9230(94)00217-O

Sawchenko, 1982, The organization of noradrenergic pathways from the brainstem to the paraventricular and supraoptic nuclei in the rat, Brain Res., 257, 275, 10.1016/0165-0173(82)90010-8

Smith, 1988, Effects of interferon alpha on performance in man: A preliminary report, Psychopharmacology, 96, 414, 10.1007/BF00216072

Tilders, 1999, Cross-sensitization between immune and non-immune stressors. A role in the etiology of depression?, Adv. Exp. Med. Biol., 461, 179, 10.1007/978-0-585-37970-8_11

Tkacs, 1999, Immune stimulation induces Fos expression in brainstem amygdala afferents, Brain Res. Bull., 48, 223, 10.1016/S0361-9230(98)00167-1

Tkacs, 1997, Central amygdala Fos expression during hypotensive or febrile, nonhypotensive endotoxemia in conscious rats, J. Comp. Neurol., 379, 592, 10.1002/(SICI)1096-9861(19970324)379:4<592::AID-CNE9>3.0.CO;2-Y

van Dam, 1992, Appearance of interleukin-1 in macrophages and in ramified microglia in the brain of endotoxin-treated rats: A pathway for the induction of non-specific symptoms of sickness?, Brain Res., 588, 291, 10.1016/0006-8993(92)91588-6

Wan, 1994, Neural and biochemical mediators of endotoxin and stress-induced c-fos expression in the rat brain, Brain Res. Bull., 34, 7, 10.1016/0361-9230(94)90179-1

Yirmiya, 1996, Endotoxin produces a depressive-like episode in rats, Brain Res., 711, 163, 10.1016/0006-8993(95)01415-2

Yirmiya, 1999, Cytokines, “depression due to a general medical condition,” and antidepressant drugs, Adv. Exp. Med. Biol., 461, 283, 10.1007/978-0-585-37970-8_16