Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade
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An, 1996, Failure to activate interleukin-1β converting enzyme-like proteases and to cleave retinoblastoma protein in drug-resistant cells, FEBS Lett., 399, 158, 10.1016/S0014-5793(96)01311-7
Boldin, 1996, Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/Apo-1- and TNF receptor–induced cell death, Cell, 85, 803, 10.1016/S0092-8674(00)81265-9
Caciola-Rosen, 1996, Apopain/cpp32 cleaves proteins that are essential for cellular repair, J. Exp. Med., 183, 1957, 10.1084/jem.183.5.1957
Chinnaiyan, 1997, Interaction of CED-4 with CED-3 and CED-9, Science, 275, 1122, 10.1126/science.275.5303.1122
de Jong, 1994, Subcellular localization of the bcl-2 protein in malignant and normal lymphoid cells, Cancer Res., 54, 256
Duan, 1996, ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B, J. Biol. Chem., 271, 16720, 10.1074/jbc.271.28.16720
Eguchi, 1997, Intracellular ATP levels determine cell death fate by apoptosis or necrosis, Cancer Res., 57, 1835
Faleiro, 1997, Multiple species of CPP32 and Mch2 are the major active caspases present in apoptotic cells, EMBO J., 16, 2271, 10.1093/emboj/16.9.2271
Fernandes-Alnemri, 1994, cpp32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein CED-3 and mammalian interleukin-1β converting enzyme, J. Biol. Chem., 269, 30761, 10.1016/S0021-9258(18)47344-9
Hengartner, 1994, C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian protooncogene bcl-2, Cell, 76, 665, 10.1016/0092-8674(94)90506-1
Hengartner, 1992, Caenorhabditis elegans gene ced-9 protects cells from programmed cell death, Nature, 356, 494, 10.1038/356494a0
Horvitz, 1994, The genetics of programmed cell death in the nematode Caenorhabditis elegans, Cold Spring Harb. Symp. Quant. Biol., 59, 377, 10.1101/SQB.1994.059.01.042
Jacobson, 1997, Programmed cell death in animal development, Cell, 88, 347, 10.1016/S0092-8674(00)81873-5
Janicke, 1996, Specific cleavage of the retinoblastoma protein by an ICE-like protease in apoptosis, EMBO J., 15, 6969, 10.1002/j.1460-2075.1996.tb01089.x
Kharbanda, 1997, Role for Bcl-xL as an inhibitor of cytosolic cytochrome C accumulation in DNA damage-induced apoptosis, Proc. Natl. Acad. Sci. USA, 94, 6939, 10.1073/pnas.94.13.6939
Kim, 1997, Overexpression of Bcl-X(L) inhibits Ara-C-induced mitochondrial loss of cytochrome c and other perturbations that activate the molecular cascade of apoptosis, Cancer Res., 57, 3115
Kluck, 1997, The release of cytochrome c from mitochondria, Science, 275, 1132, 10.1126/science.275.5303.1132
Krajewski, 1993, Investigation of the subcellular distribution of the bcl-2 oncoprotein, Cancer Res., 53, 4701
Lazebnik, 1995, Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution, Proc. Natl. Acad. Sci. USA, 92, 9042, 10.1073/pnas.92.20.9042
Leist, 1997, Intracellular adenosine triphosphate (ATP) concentration, J. Exp. Med., 185, 1481, 10.1084/jem.185.8.1481
Liu, 1996, Purification and characterization of an interleukin-1β converting enzyme family of protease that activates cysteine protease p32, J. Biol. Chem., 271, 13371, 10.1074/jbc.271.23.13371
Liu, 1996, Induction of apoptotic program in cell-free extracts, Cell, 86, 147, 10.1016/S0092-8674(00)80085-9
Liu, 1997, DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis, Cell, 89, 175, 10.1016/S0092-8674(00)80197-X
Martins, 1997, Activation of multiple interleukin-1β converting enzyme homologues in cytosol and nuclei of HL-60 cells during etoposide-induced apoptosis, J. Biol. Chem., 272, 7421, 10.1074/jbc.272.11.7421
Monaghan, 1992, Ultrastructural localization of bcl-2 protein, J. Hist. Cytochem., 40, 1819, 10.1177/40.12.1453000
Muzio, 1996, FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/Apo-1) death-inducing signaling complex, Cell, 85, 817, 10.1016/S0092-8674(00)81266-0
Neer, 1994, The ancient regulatory-protein family of WD-repeat proteins, Nature, 371, 297, 10.1038/371297a0
Nicholson, 1995, Identification and inhibition of the ICE/CED-3 protease necessory for mammalian apoptosis, Nature, 376, 37, 10.1038/376037a0
Oltvai, 1993, Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death, Cell, 74, 609, 10.1016/0092-8674(93)90509-O
Orth, 1996, The CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin A, J. Biol. Chem., 271, 16443, 10.1074/jbc.271.28.16443
Sambrook, 1989
Seshagiri, 1997, Caenorhabditis elegans CED-4 stimulates CED-3 processing and CED-3-induced apoptosis, Curr. Biol., 7, 455, 10.1016/S0960-9822(06)00216-8
Shaham, 1996, Developing Caenorhabditis elegans neurons may contain both cell-death protective and killer activities, Genes Dev., 10, 578, 10.1101/gad.10.5.578
Shaham, 1996, An alternative spliced C. elegans ced-4 RNA encodes a novel cell death inhibitor, Cell, 86, 201, 10.1016/S0092-8674(00)80092-6
Skoog, 1974, Nuclear and cytoplasmic pools of deoxyribonucleoside triphosphates in Chinese hamster ovary cells, J. Biol. Chem., 249, 6434, 10.1016/S0021-9258(19)42175-3
Sondek, 1997, Crystal structure of a Ga protein bg dimer at 2.1 A resolution, Nature, 379, 369, 10.1038/379369a0
Song, 1996, DNA-dependent protein kinase catalytic subunit, EMBO J., 15, 3238, 10.1002/j.1460-2075.1996.tb00688.x
Spector, 1997, Interaction between the C. elegans cell-death regulators CED-9 and CED-4, Nature, 385, 653, 10.1038/385653a0
Srinivasula, 1996, The Ced-3/Interleukin 1 converting enzyme-like homolog Mch6 and the lamin-cleaving enzyme Mch2 are substrates for the apoptotic mediator CPP32, J. Biol. Chem., 271, 27099, 10.1074/jbc.271.43.27099
Srinivasula, 1996, Molecular ordering of the Fas-apoptotic pathway, Proc. Natl. Acad. Sci. USA., 93, 14486, 10.1073/pnas.93.25.14486
Takahashi, 1996, Cleavage of lamin A by Mch2 α but not CPP32, Proc. Natl. Acad. Sci. USA, 93, 8395, 10.1073/pnas.93.16.8395
Takahashi, 1997, Affinity labeling displays the stepwise activation of ICE-related proteases by Fas, staurosporine, and CrmA-sensitive caspase-8, Oncogene, 14, 2741, 10.1038/sj.onc.1201131
Tewari, 1995, Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase, Cell, 81, 801, 10.1016/0092-8674(95)90541-3
Thornberry, 1992, A novel heterodimeric cysteine protease is required for interleukin-1β processing in monocytes, Nature, 356, 768, 10.1038/356768a0
Ubeda, 1997, The large subunit of the DNA replication complex C (DSEB/RF-C140) cleaved and inactivated by caspase-3 (CPP32/YAMA) during fas-induced apoptosis, J. Biol. Chem., 272, 19562, 10.1074/jbc.272.31.19562
Vaux, 1992, Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2, Science, 258, 1955, 10.1126/science.1470921
Walker, 1982, Distantly related sequence in the α- and β-subunits of ATP synthase, myosin, kinase, and other ATP-requiring enzymes and a common nucleotide binding fold, EMBO J., 1, 945, 10.1002/j.1460-2075.1982.tb01276.x
Wall, 1995, The structure of the G protein heterotrimer Giαβ1γ2, Cell, 83, 1047, 10.1016/0092-8674(95)90220-1
Wang, 1994, Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death, Cell, 78, 739, 10.1016/S0092-8674(94)90422-7
Wang, 1996, Cleavage of sterol regulatory element binding proteins (SREBPs) by cpp32 during apoptosis, EMBO J., 15, 1012, 10.1002/j.1460-2075.1996.tb00438.x
Wu, 1997, Interaction and regulation of subcellular localization of CED-4 by CED-9, Science, 275, 1126, 10.1126/science.275.5303.1126
Xue, 1996, The Caenorhabditis elegans cell-death protein CED-3 is a cysteine protease with substrate specificities similar to those of human cpp32 protease, Genes Dev., 10, 1073, 10.1101/gad.10.9.1073
Yuan, 1990, Genetics mosaic analysis of ced-3 and ced-4, two genes that control programmed cell death in the nematode C. elegans, Dev. Biol., 138, 33, 10.1016/0012-1606(90)90174-H
Yuan, 1992, The C. elegans cell death gene ced-4 encodes a novel protein and is expressed during the period of extensive programmed cell death, Development, 116, 309, 10.1242/dev.116.2.309
Yuan, 1993, The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β converting enzyme, Cell, 75, 641, 10.1016/0092-8674(93)90485-9