Cytochrome P-450-linked monooxygenase system and drug-induced spectral interactions in human liver microsomes

Chemico-Biological Interactions - Tập 9 - Trang 205-216 - 1974
Olavi Pelkonen1, Eero H. Kaltiala1, Teuvo K.I. Larmi1, Niilo T. Kärki1
1Department of Pharmacology and Department of Surgery, University Of Oulu, SF-90220 Oulu 22 (Finland)

Tài liệu tham khảo

Conney, 1967, Pharmacological implications of microsomal enzyme induction, Pharmacol. Rev., 19, 317 Kuntzman, 1966, Metabolism of drugs and carcinogens by human liver enzymes, J. Pharmacol. Exptl. Therap., 152, 151 Alvares, 1969, Cytochromes P-450 and b5 in human liver microsomes, Clin. Pharmacol. Therap., 10, 655, 10.1002/cpt1969105655 Ackermann, 1970, Die Aktivität der N- and O-Demethylase in der Leber des Menschen, Biochem. Pharmacol., 19, 327, 10.1016/0006-2952(70)90190-5 Raj, 1971, Studies on drug metabolism in human liver, Chem.-Biol. Interactions, 3, 303, 10.1016/0009-2797(71)90070-6 Nelson, 1971, Oxidative drug metabolism in human liver microsomes, J. Pharmacol. Exptl. Therap., 178, 580 Davies, 1971, Mechanism of hepatic drug oxidation and its relationship to individual differences in rates of oxidation in man, Ann. N.Y. Acad. Sci., 179, 411, 10.1111/j.1749-6632.1971.tb46918.x Schoene, 1972, Determination of drug metabolizing enzymes in needle biopsies of human liver, European J. Clin. Pharmacol., 4, 65, 10.1007/BF00562499 Ackermann, 1972, Entalkylierung von Äthylmorphin and p-C-Hydroxylierung von Anilin in Lebermikrosomen von Menschen and von männlichen and weiblichen Ratten, Biochem. Pharmacol., 21, 2169, 10.1016/0006-2952(72)90032-9 Black, 1973, Hepatic bilirubin UDP-glucuronyl transferarse activity and cytochrome P-450 content in a surgical population, and the effects of preoperative drug therapy, J. Lab. Clin. Med., 81, 704 Gold, 1973, Dimethylaniline N-oxidase and aminopyrine N-demethylase activities of human liver tissues, Xenobiotica, 3, 179, 10.3109/00498257309151512 Darby, 1972, Apparent Michaelis constants for the metabolism of (ureyl-14C) tolbutamide by human liver microsomal preparations, Biochem. Pharmacol., 21, 407, 10.1016/0006-2952(72)90352-8 Greim, 1970, The influence of phenobarbital on the turnover of hepatic microsomal cytochrome b5 and cytochrome P-450 hemes in the rat, Biochim. Biophys. Acta, 201, 20, 10.1016/0304-4165(70)90005-X Omura, 1964, The carbon-monoxide-binding pigment of liver microsomes, I. Evidence for its hemoprotein nature, J. Biol. Chem., 239, 2370, 10.1016/S0021-9258(20)82244-3 Masters, 1967, The preparation and properties of microsomal TPNH-cytochrome c reductase from pig liver, Vol. X, 565 Layne, 1954, Spectrophotometric and turbidimetric methods for measuring proteins, Vol. I, 447 Pelkonen, 1973, Comparison of activities of drug-metabolizing enzymes in human fetal and adult livers, Clin. Pharmacol. Therap., 14, 840, 10.1002/cpt1973145840 Kamath, 1971, A Simple procedure for the isolation of rat liver microsomes, FEBS Letters, 17, 90, 10.1016/0014-5793(71)80571-9 Cinti, 1972, Kinetic parameters of drug-metabolizing enzymes in Ca2+-sedimented microsomes from rat liver, Biochem. Pharmacol., 21, 3249, 10.1016/0006-2952(72)90089-5 Sladek, 1966, Evidence for a new P-450 hemoprotein in hepatic microsomes from methylcholanthrene treated rats, Biochem. Biophys. Res. Commun., 24, 668, 10.1016/0006-291X(66)90376-7 Hildebrandt, 1968, Cytochrome P-450 of liver microsomes — one pigment or many?, Biochem. Biophys. Res. Commun., 30, 607, 10.1016/0006-291X(68)90555-X Alvares, 1967, Studies on the induction of CO-binding pigments in liver microsomes by phenobarbital and 3-methylcholanthrene, Biochem. Biophys. Res. Commun., 29, 521, 10.1016/0006-291X(67)90515-3 Kuntzman, 1971, The importance of cytochrome P-450 and P-448 in determining the specificity of the reconstituted liver microsomal hydroxylation system, Chem.-Biol. Interactions, 3, 287, 10.1016/0009-2797(71)90063-9 Lu, 1972, Partial purification of cytochrome P-450 and P-448 from rat liver microsomes, Biochem. Biophys. Res. Commun., 46, 1334, 10.1016/S0006-291X(72)80121-9 Lu, 1972, Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds, and endogenous substrates, II. Role of the cytochrome P-450 and P-448 fractions in drug and steroid hydroxylations, J. Biol. Chem., 247, 1727, 10.1016/S0021-9258(19)45536-1 Pelkonen, 1972, Effect of maternal cigarette smoking on 3,4-benzpyrene and N-methylaniline metabolism in human fetal liver and placenta, Toxicol. Appl. Pharmacol., 23, 399, 10.1016/0041-008X(72)90042-7 Rane, 1973, Drug metabolism in the human fetus, 287 Schenkman, 1972, The nature of the reverse type I (modified type II) spectral change in liver microsomes, Biochemistry, 11, 4243, 10.1021/bi00773a008 Darby, 1973, The metabolism of (ureyl-14C) tolbutamide in vitro and in vivo in man, Life Sci., 13, 97, 10.1016/0024-3205(73)90184-7