Cyclin kinase inhibitors add a new dimension to cell cycle control
Tài liệu tham khảo
Hinds, 1994, Tumor suppressor genes, Curr Opin Genet Devel, 4, 135, 10.1016/0959-437X(94)90102-3
Buchkovich, 1989, The retinoblastoma protein is phosphorylated during specific phases of the cell cycle, Cell, 58, 1097, 10.1016/0092-8674(89)90508-4
Nevins, 1994, Cell cycle targets of the DNA tumor viruses, Curr Opin Genet Devel, 4, 130, 10.1016/0959-437X(94)90101-5
Kastan, 1992, mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia, Cell, 71, 587, 10.1016/0092-8674(92)90593-2
Nurse, 1994, Ordering S phase and M phase in the cell cycle, Cell, 79, 547, 10.1016/0092-8674(94)90539-8
Sherr, 1993, Mammalian G1 cyclins, Cell, 73, 1059, 10.1016/0092-8674(93)90636-5
Schauer, 1994, Cyclin D1 overexpression vs retinoblastoma inactivation: implications for growth control evasion in non-small cell and small cell lung cancer, 91, 7827
Keyomarsi, 1993, Redundant cyclin overexpression and gene amplification in breast cancer cells, 90, 1112
Gillett, 1994, Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining, Cancer Res, 54, 1812
Lammie, 1991, D11S287, a putative oncogene on chromosome 11q13, is amplified and expressed in squamous cell and mammary carcinomas and linked to BCL-1, Oncogene, 6, 439
Tam, 1994, Differential expression and regulation of cyclin D1 protein in normal and tumor human cells: association with cdk4 is required for cyclin D1 function in G1 progression, Oncogene, 9, 2663
Pietenpol, 1990, TGFβ1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains, Cell, 61, 777, 10.1016/0092-8674(90)90188-K
Laiho, 1990, Growth inhibition by TGFβ linked to suppression of retinoblastoma protein phosphorylation, Cell, 62, 175, 10.1016/0092-8674(90)90251-9
Howe, 1991, Transforming growth factor β1 inhibition of p34cdc2 phosphorylation and histone H1 kinase activity is associated with G1/S phase growth arrest, Mol Cell Biol, 11, 1185, 10.1128/MCB.11.3.1185
Carpenter, 1979, Epidermal growth factor, Annu Rev Biochem, 48, 193, 10.1146/annurev.bi.48.070179.001205
Heldin, 1990, Signal transduction by the receptors for platelet-derived growth factor, J Cell Sci, 96, 193, 10.1242/jcs.96.2.193
Xiong, 1992, D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA, Cell, 71, 505, 10.1016/0092-8674(92)90518-H
Harper, 1993, The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases, Cell, 75, 805, 10.1016/0092-8674(93)90499-G
El-Deiry, 1993, WAF1, a potential mediator of p53 tumor suppression, Cell, 75, 817, 10.1016/0092-8674(93)90500-P
Noda, 1994, Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen, Exp Cell Res, 211, 90, 10.1006/excr.1994.1063
Li Jenkins, 1994, Cell cycle expression and p53 regulation of the cyclin-dependent kinase inhibitor p21, Oncogene, 9, 2261
El-Deiry, 1994, WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis, Cancer Res, 54, 1169
Lin, 1994, Constitutive expression of B-myb can bypass p53-induced Waf 1/Cip1-mediated G1 arrest, 91, 10079
Travali, 1991, Constitutively activated c-myb abrogates the requirement for insulin-like growth factor 1 in 3T3 fibroblasts, Mol Cell Biol, 11, 731, 10.1128/MCB.11.2.731
Harris, 1993, p53: at the crossroads of molecular carcinogenesis and risk assessment, Science, 262, 1980, 10.1126/science.8266092
Shiohara, 1994, Absence of WAF1 mutations in a variety of human malignancies, Blood, 11, 3781, 10.1182/blood.V84.11.3781.bloodjournal84113781
Li, 1995, Polymorphisms and probable lack of mutation in the WAF1-CIP1 gene in colorectal cancer, Oncogene, 10, 599
Chedid, 1994, A single nucleotide substitution at codon 31 (Ser-Arg) defines a polymorphism in a highly conserved region of the p53-inducible gene WAF1/CIP1, Oncogene, 9, 3021
Bhatia, 1995, A mutant p21 cyclindependent kinase inhibitor isolated from a Burkitt's lymphoma, Cancer Res, 55, 1431
Gaidano, 1991, p53 mutations in human lymphoid malignancies: association with Burkitt's lymphoma and chronic lymphocytic leukemia, 88, 5413
Michieli, 1994, Induction of WAF1/CIP1 by a p53-independent pathway, Cancer Res, 54, 3391
Zhang, 1995, p53-independent induction of WAF1/CIP1 in human leukemia cells is correlated with growth arrest accompanying monocyte/macrophage differentiation, Cancer Res, 55, 668
Sheikh, 1994, Mechanisms of regulation of WAF1/Cip1 gene expression in human breast carcinoma: role of p53-dependent and independent signal transduction pathways, Oncogene, 9, 3407
Steinman, 1994, Induction of p21 (WAF1/CIP1) during differentiation, Oncogene, 9, 3389
Strausfeld, 1994, Cip1 blocks the initiation of DNA replication in Xenopus extracts by inhibition of cyclin-dependent kinases, Curr Biol, 4, 876, 10.1016/S0960-9822(00)00196-2
Waga, 1994, The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA, Nature, 369, 574, 10.1038/369574a0
Li, 1994, Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair, Nature, 371, 534, 10.1038/371534a0
Shivji, 1992, Cip1 inhibits DNA replication but not PCNA-dependent mucleotide excision repair. Curr Biol 1994, 4, 1062-1068. 39. Lane DP. p53: Guardian of the genome, Nature, 358, 15
Serrano, 1993, A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4, Nature, 366, 704, 10.1038/366704a0
Hinds, 1992, Regulation of retinoblastoma protein functions by ectopic expression of human cyclins, Cell, 70, 993, 10.1016/0092-8674(92)90249-C
Nevins, 1992, E2F: a link between the Rb tumor suppressor protein and viral oncoproteins, Science, 258, 424, 10.1126/science.1411535
Nawroz, 1994, Allelotype of head and neck squamous cell carcinoma, Cancer Res, 54, 1152
Ah-See, 1994, An allelotype of squamous cell carcinoma of the head and neck using microsatellite markers, Cancer Res, 54, 1617
Cairns, 1994, Homozygous deletions of 9p21 in primary human bladder tumors detected by comparative multiplex polymerase chain reaction, Cancer Res, 54, 1422
Cairns, 1993, Initiation of bladder cancer may involve deletion of a tumor suppressor gene on chromosome 9, Oncogene, 8, 1083
Diaz, 1990, Deletions of interferon genes in acute lymphoblastic leukemia, N Engl J Med, 332, 77, 10.1056/NEJM199001113220202
Fountain, 1992, Homozygous deletions within human chromosome band 9p21 in melanoma, 89, 10557
Olopade, 1993, Homozygous loss of the interferon genes defines the critical region on 9p that is deleted in lung cancers, Cancer Res, 53, 2410
Kamb, 1994, A cell cycle regulator potentially involved in genesis of many tumor types, Science, 264, 436, 10.1126/science.8153634
Nobori, 1994, Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers, Nature, 368, 753, 10.1038/368753a0
Cairns, 1994, Rates of p16(MTS1) mutations in primary tumors with 9p loss, Science, 265, 415, 10.1126/science.8023167
Spruck, 1994, p16 gene in uncultured tumors, Nature, 370, 183, 10.1038/370183a0
Kamb, 1994, Rates of p16 (MTS1) mutations in primary tumors with 9p loss, Science, 265, 416, 10.1126/science.265.5170.416
Bonetta, 1994, Open questions on p16, Nature, 370, 180, 10.1038/370180a0
Mori, 1994, Frequent somatic mutation of the MTS1/CDK4I (Multiple Tumor Suppressor/Cyclin Dependent Kinase 4 Inhibitor) gene in esophageal squamous cell carcinoma, Cancer Res, 54, 3396
Yeudall, 1994, MTS1/CDK4I is altered in cell lines derived from primary and metastatic oral squamous cell carcinoma, Carcinogenesis, 15, 2683, 10.1093/carcin/15.12.2683
Porterfield, 1992, Induction of senescence in two neoplastic cell lines by microcell transfer of human chromosome 9, 33, 73
Loughran, 1994, Loss of heterozygosity of chromosome 9p21 is associated with the immortal phenotype of neoplastic human head and neck keratinocytes, Cancer Res, 54, 5045
Okamoto, 1994, Mutations and altered expression of p16INK4 in human cancer, 91, 11045
Otterson, 1994, Absence of p16INK4 protein is restricted to the subset of lung cancer lines that retains wildtype RB, Oncogene, 9, 3375
Liu, 1995, CDKN2 (MTS1) tumor suppressor gene mutations in human tumor cell lines, Oncogene, 10, 1061
Schmidt, 1994, CDKN2 (p16/MTS1) gene deletion or CDK4 amplification occurs in the majority of glioblastomas, Cancer Res, 54, 6321
He, 1994, CDK4 amplification is an alternative mechanism to p16 gene homozygous deletion in glioma cell lines, Cancer Res, 54, 5804
Walker, 1995, Homozygous deletions of the multiple tumor suppressor gene 1 in the progression of human astrocytomas, Cancer Res, 55, 20
Zhang, 1994, Higher frequency of alterations in the p16/CDKN2 gene in squamous cell carcinoma cell lines than in primary tumors of the head and neck, Cancer Res, 54, 5050
Parry, 1995, Lack of cyclin D-Cdk complexes in Rb-negative cells correlates with high levels of p16INK4/MTS1 tumour suppressor gene product, EMBO J, 503, 10.1002/j.1460-2075.1995.tb07026.x
Tam, 1994, Differential expression and cell cycle regulation of the cyclin-dependent kinase inhibitor p16Ink4, Cancer Res, 54, 5816
Cannon-Albright, 1992, Assignment of a locus for familial melanoma, MLM, to chromosome 9p13–22, Science, 258, 1148, 10.1126/science.1439824
Hussussian, 1994, Germline p16 mutations in familial melanoma, Nature Genet, 8, 15, 10.1038/ng0994-15
Kamb, 1994, Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus, Nature Genet, 8, 21, 10.1038/ng0994-22
Caldas, 1994, Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma, Nature Genet, 8, 27, 10.1038/ng0994-27
Ivinson, 1994, p16 and familial melanoma, Nature, 371, 180, 10.1038/371180a0
Serrano, 1995, Inhibition of ras-induced proliferation and cellular transformation by p16ink4, Science, 267, 249, 10.1126/science.7809631
Whyte, 1988, Association between an oncogene and an anti-oncogene: the adeno virus E1A protein binds to the retinoblastoma gene product, Nature, 334, 124, 10.1038/334124a0
Arap, 1995, Replacement of the p16/CDKN2 gene suppresses human glioma cell growth, Cancer Res, 55, 1351
Hannon, 1994, p15INK4B is a potential effector of TGF-β-induced cell cycle arrest, Nature, 371, 257, 10.1038/371257a0
Guan, 1994, Growth suppression by p18, a p16INK4/MTS1 and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function, Genes Devel, 2939, 10.1101/gad.8.24.2939
Hirai, 1995, Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6, Mol Cell Biol, 15, 2672, 10.1128/MCB.15.5.2672
Chan, 1995, Identification of human and mouse p19, a novel CDK4 and CDK6 inhibitor with homology to p16ink4, Mol Cell Biol, 15, 2682, 10.1128/MCB.15.5.2682
Okamoto, 1995, Mutations in the p16INK4/MTS1/CDKN2, p15INK4B/MTS2, and p18 genes in primary and metastatic lung cancer, Cancer Res, 55, 1448
Otsuki, 1995, Involvement of CD KN2(p16INK4A/MTS1) and p15INK4B/MTS2 in human leukemias and lymphomas, Cancer Res, 55, 1436
Jen, 1994, Deletion of p16 and p15 genes in brain tumors, Cancer Res, 54, 6353
Toyoshima, 1994, p27, a novel inhibitor of G1 cyclinCdk protein kinase activity, is related to p21, Cell, 78, 67, 10.1016/0092-8674(94)90573-8
Polyak, 1994, Cloning of p27kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitotic signals, Cell, 78, 59, 10.1016/0092-8674(94)90572-X
Slingerland, 1994, A novel inhibitor of cyclin-Cdk activity detected in transforming growth factor β-arrested epithelial cells, Mol Cell Biol, 14, 3683, 10.1128/MCB.14.6.3683
Nakanishi, 1995, Identification of the active region of the DNA synthesis inhibitory gene p21Sdi1/Cip1/WAF1, EMBO J, 555, 10.1002/j.1460-2075.1995.tb07031.x
Bullrich, 1995, Chromosomal mapping of members of the cdc2 family of protein kinases, cdk3, cdk6, PISSLRE, and PITALRE, and a cdk inhibitor, p27Kip1, to regions involved in human cancer, Cancer Res, 55, 1199
Pietenpol, 1995, Assignment of the p27Kip1 gene to 12p13 and its analysis in leukemias, Cancer Res, 55, 1206
Ponce-Castaneda, 1995, p27Kip1:chromosomal mapping to 12p12 and absence of mutations in human tumors, Cancer Res, 55, 1211
Hengst, 1994, A cell cycle-regulated inhibitor of cyclin-dependent kinases, 91, 5291
Geng, 1993, Transforming growth factor β effects on expression of G1 cyclins and cyclin-dependent protein kinases, 90, 10315
Ewen, 1993, TGFβ inhibition of cdk4 synthesis is linked to cell cycle arrest, Cell, 74, 1009, 10.1016/0092-8674(93)90723-4
Ewen, 1995, p53-dependent repression of CDK4 translation in TGF-β-induced G, cell-cycle arrest, Genes Devel, 9, 204, 10.1101/gad.9.2.204
Peters, 1994, Stifled by inhibitions, Nature, 371, 204, 10.1038/371204a0
Ravitz, 1995, Transforming growth factor β-induced activation of cyclin E-cdk2 kinase and downregulation of p27Kip1 in C3H 10T1/2 mouse fibroblasts, Cancer Res, 55, 1413
Li, 1995, Potential role of WAF1/Cip1/p21 as a mediator of TGF-β cytoinhibitory effect, J Biol Chem, 270, 4971, 10.1074/jbc.270.10.4971
Gill, 1981, Increased phosphotyrosine content and inhibition of proliferation in EGF-treated A431 cells, Nature, 293, 305, 10.1038/293305a0
Firpo, 1994, Inactivation of a Cdk2 inhibitor during interleukin 2-induced proliferation of human T lymphocytes, Mol Cell Biol, 14, 4889, 10.1128/MCB.14.7.4889
Parker, 1995, p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells, Science, 267, 1024, 10.1126/science.7863329
Halevy, 1995, Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD, Science, 267, 1018, 10.1126/science.7863327
Skapek, 1995, Inhibition of myogenic differentiation in proliferating myoblasts by cyclin D1-dependent kinase, Science, 267, 1022, 10.1126/science.7863328
