Cyclin-dependent kinase 5, Munc18a and Munc18-interacting protein 1/X11α protein up-regulation in Alzheimer’s disease

Neuroscience - Tập 138 - Trang 511-522 - 2006
E.H. Jacobs1, R.J. Williams1, P.T. Francis1
1Wolfson Centre for Age-Related Diseases, Guy’s, King’s and St Thomas’ Schools of Biomedical Sciences, King’s College London, St. Thomas Street, London SE1 1UL, UK

Tài liệu tham khảo

Ahlijanian, 2000, Hyperphosphorylated tau and neurofilament and cytoskeletal disruptions in mice overexpressing human p25, an activator of cdk5, Proc Natl Acad Sci U S A, 97, 2910, 10.1073/pnas.040577797 Alvarez, 2001, A cdk5-p35 stable complex is involved in the β-amyloid-induced deregulation of cdk5 activity in hippocampal neurons, Exp Cell Res, 264, 266, 10.1006/excr.2001.5152 1987 Beach, 1992, Cholinergic fiber loss occurs in the absence of synaptophysin depletion in Alzheimer’s disease primary visual cortex, Neurosci Lett, 142, 253, 10.1016/0304-3940(92)90385-K Biederer, 2000, Mints as adaptors. Direct binding to neurexins and recruitment of Munc18, J Biol Chem, 275, 39803, 10.1074/jbc.C000656200 Biederer, 2002, Regulation of APP-dependent transcription complexes by Mint/X11s, J Neurosci, 22, 7340, 10.1523/JNEUROSCI.22-17-07340.2002 Borg, 1998, The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion, J Biol Chem, 273, 14761, 10.1074/jbc.273.24.14761 Braak, 1991, Neuropathological staging of Alzheimer-related changes, Acta Neuropathol, 82, 239, 10.1007/BF00308809 Braak, 1998, Evolution of Alzheimer’s disease related cortical lesions, J Neural Transm Suppl, 54, 97, 10.1007/978-3-7091-7508-8_9 Bradford, 1976, A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding, Anal Biochem, 72, 248, 10.1016/0003-2697(76)90527-3 Brun, 1983, An overview of light and electron microscopic changes, 37 Cruz, 2003, Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles, Neuron, 40, 471, 10.1016/S0896-6273(03)00627-5 DeKosky, 2002, Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment, Ann Neurol, 51, 145, 10.1002/ana.10069 Delacourte, 1999, The biochemical pathway of neurofibrillary degeneration in aging and Alzheimer’s disease, Neurology, 52, 1158, 10.1212/WNL.52.6.1158 Dhavan, 2001, A decade of CDK5, Nat Rev Mol Cell Biol, 2, 749, 10.1038/35096019 Fletcher, 1999, Regulation of exocytosis by cyclin-dependent kinase 5 via phosphorylation of Munc18, J Biol Chem, 274, 4027, 10.1074/jbc.274.7.4027 Folstein, 1975, “Mini-Mental State”: A practical method for grading the cognitive state of patients for the clinician, J Psychiat Res, 12, 189, 10.1016/0022-3956(75)90026-6 Francis, 1993, Cortical pyramidal neurone loss may cause glutamatergic hypoactivity and cognitive impairment in Alzheimer’s disease, J Neurochem, 60, 1589, 10.1111/j.1471-4159.1993.tb13381.x Francis, 1999, The cholinergic hypothesis of Alzheimer’s disease, J Neurol Neurosurg Psychiatry, 66, 137, 10.1136/jnnp.66.2.137 Gallwitz, 2003, The riddle of the Sec1/Munc-18 proteins, Trends Biochem Sci, 28, 113, 10.1016/S0968-0004(03)00028-8 Hardy, 1985, The patients dying after long terminal phase have acidotic brains, J Neural Transm, 61, 253, 10.1007/BF01251916 Haug, 1996, Decreased inositol (1,4,5)-triphosphate receptor levels in Alzheimer’s disease cerebral cortex, Neurodegeneration, 5, 169, 10.1006/neur.1996.0024 Hill, 2003, Munc18 interacting proteins, J Biol Chem, 278, 36032, 10.1074/jbc.M301632200 Ho, 2003, A role for Mints in transmitter release, Proc Natl Acad Sci U S A, 100, 1409, 10.1073/pnas.252774899 Ho, 2002, Synergistic effects of Munc18a and X11 proteins on amyloid precursor protein metabolism, J Biol Chem, 30, 27021, 10.1074/jbc.M201823200 Hofman, 1991, The prevalence of dementia in Europe, Int J Epidemiol, 20, 736, 10.1093/ije/20.3.736 Honer, 1992, Regional synaptic pathology in Alzheimer’s disease, Neurobiol Aging, 13, 375, 10.1016/0197-4580(92)90111-A Hope, 1992, The Present Behavioural Examination (PBE), Psychol Med, 22, 223, 10.1017/S0033291700032888 Hope, 1997, Behaviour changes in dementia. I. Point of entry data of a prospective study, Int J Geriatr Psychiatry, 12, 1062, 10.1002/(SICI)1099-1166(199711)12:11<1062::AID-GPS675>3.0.CO;2-N Hope, 1997, Behaviour changes in dementia. II. Are there behavioural syndromes?, Int J Geriatr Psychiatry, 12, 1074, 10.1002/(SICI)1099-1166(199711)12:11<1074::AID-GPS696>3.0.CO;2-B Hope, 1999, Natural history of behavioural changes and psychiatric symptoms in Alzheimer’s disease, Br J Psychiatry, 174, 39, 10.1192/bjp.174.1.39 Hsiao, 1996, Correlative memory deficits, Aβ elevation, and amyloid plaques in transgenic mice, Science, 274, 99, 10.1126/science.274.5284.99 Ikonomovic, 2003, Cholinergic plasticity in hippocampus of individuals with mild cognitive impairment, J Alzheimers Dis, 5, 39, 10.3233/JAD-2003-5106 Irizarry, 1997, APPSw transgenic mice develop age-related Aβ deposits and neuropil abnormalities, but no neuronal loss in CA1, J Neuropathol Exp Neurol, 56, 965, 10.1097/00005072-199709000-00002 King, 2002, Maintained synaptophysin immunoreactivity in Tg2576 transgenic mice during aging, Brain Res, 926, 58, 10.1016/S0006-8993(01)03294-2 King, 2003, X11α modulates secretory and endocytotic trafficking and metabolism of amyloid precursor protein, Neuroscience, 120, 143, 10.1016/S0306-4522(03)00284-7 King, 2004, X11α impairs γ- but not β-cleavage of amyloid precursor protein, J Neurochem, 88, 971, 10.1046/j.1471-4159.2003.02234.x Lee, 2003, The neuronal adaptor protein X11α reduces Aβ levels in the brains of Alzheimer’s APPswe Tg2576 transgenic mice, J Biol Chem, 278, 47025, 10.1074/jbc.M300503200 Lee, 2004, The neuronal adaptor protein X11β reduces amyloid β-protein levels and amyloid plaque formation in the brains of transgenic mice, J Biol Chem, 279, 49099, 10.1074/jbc.M405602200 Lee, 2000, Neurotoxicity induces cleavage of p35 to p25 by calpain, Nature, 405, 360, 10.1038/35012636 Masliah, 1989, Immunohistochemical quantification of the synapse-related protein synaptophysin in Alzheimer disease, Neurosci Lett, 103, 234, 10.1016/0304-3940(89)90582-X Masliah, 1991, Cortical and subcortical patterns of synaptophysinlike immunoreactivity in Alzheimer’s disease, Am J Pathol, 138, 235 McKhann, 1984, Clinical diagnosis of Alzheimer’s disease, Neurology, 34, 939, 10.1212/WNL.34.7.939 McLoughlin, 1999, Mint2/X11-like colocalizes with the Alzheimer’s disease amyloid precursor protein and is associated with neuritic plaques in Alzheimer’s disease, Eur J Neurosci, 11, 1988, 10.1046/j.1460-9568.1999.00610.x Mirra, 1991, The Consortium to Establish a Registry for Alzheimer’s Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer’s disease, Neurology, 41, 479, 10.1212/WNL.41.4.479 Mori, 2002, Alteration of methamphetamine-induced striatal dopamine release in mint-1 knockout mice, Neurosci Res, 43, 251, 10.1016/S0168-0102(02)00041-X Mueller, 2000, Modulation of amyloid precursor protein metabolism by X11α/Mint-1, J Biol Chem, 275, 39302, 10.1074/jbc.M008453200 Nishimura, 2000, Changes in Mint1, a novel synaptic protein, after transient global ischemia in mouse hippocampus, J Cereb Blood Flow Metab, 20, 1437, 10.1097/00004647-200010000-00005 Noble, 2003, Cdk5 is a key factor in tau aggregation and tangle formation in vivo, Neuron, 38, 555, 10.1016/S0896-6273(03)00259-9 Okamoto, 1997, Mints, Munc18-interacting proteins in synaptic vesicle exocytosis, J Biol Chem, 272, 31459, 10.1074/jbc.272.50.31459 Okamoto, 1998, Mint3, Eur J Cell Biol, 77, 161, 10.1016/S0171-9335(98)80103-9 Palmer, 1987, Monoaminergic innervation of the frontal and temporal lobes in Alzheimer’s disease, Brain Res, 401, 231, 10.1016/0006-8993(87)91408-9 Patrick, 1998, P35, the neuronal-specific activator of cyclin-dependent kinase 5 (cdk5) is degraded by the ubiquitin-proteasome pathway, J Biol Chem, 273, 24057, 10.1074/jbc.273.37.24057 Patrick, 1999, Conversion of p35 to p25 deregulates cdk5 activity and promotes neurodegeneration, Nature, 402, 615, 10.1038/45159 Pérez-Brangulí, 2002, Munc 18a binding to syntaxin 1A and 1B isoforms defines its localization at the plasma membrane and blocks SNARE assembly in a three-hybrid system assay, Mol Cell Neurosci, 20, 169, 10.1006/mcne.2002.1122 Rizo, 2002, SNAREs and Munc18 in synaptic vesicle fusion, Nat Rev Neurosci, 3, 641, 10.1038/nrn898 Roth, 1986, CAMDEX, Br J Psychiatry, 149, 698, 10.1192/bjp.149.6.698 Ruiz-Montasell, 1996, Differential distribution of syntaxin isoforms 1A and 1B in the rat central nervous system, Eur J Neurosci, 8, 2544, 10.1111/j.1460-9568.1996.tb01548.x Sastre, 1998, The X11α protein slows cellular amyloid precursor protein processing and reduces Aβ40 and Aβ42 secretion, J Biol Chem, 273, 22351, 10.1074/jbc.273.35.22351 Savage, 2002, Activation of c-Jun N-terminal kinase and p38 in an Alzheimer’s disease model is associated with amyloid deposition, J Neurosci, 22, 3376, 10.1523/JNEUROSCI.22-09-03376.2002 Scorza, 2003, Levels of the synaptic protein X11alpha/mint1 are increased in hippocampus of rats with epilepsy, Epilepsy Res, 57, 49, 10.1016/j.eplepsyres.2003.10.010 Shuang, 1998, Regulation of Munc-18/syntaxin 1A interaction by cyclin-dependent kinase 5 in nerve endings, J Biol Chem, 273, 4957, 10.1074/jbc.273.9.4957 Smith, 2002, Cdk5 behind the wheel, Trends Cell Biol, 12, 28, 10.1016/S0962-8924(01)02181-X Sze, 1997, Loss of the presynaptic vesicle protein synaptophysin in hippocampus correlates with cognitive decline in Alzheimer disease, J Neuropathol Exp Neurol, 56, 933, 10.1097/00005072-199708000-00011 Takashima, 2001, Involvement of cyclin dependent kinase 5 activator p25 on tau phosphorylation in mouse brain, Neurosci Lett, 306, 37, 10.1016/S0304-3940(01)01864-X Takeuchi, 2001, Age-related amyloid β deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid β precursor protein Swedish mutant is not associated with global neuronal loss, Am J Pathol, 157, 331, 10.1016/S0002-9440(10)64544-0 Tandon, 2003, Brain levels of CDK5 activator p25 are not increased in Alzheimer’s or other neurodegenerative diseases with neurofibrillary tangles, J Neurochem, 86, 572, 10.1046/j.1471-4159.2003.01865.x Taniguchi, 2001, Calpain-mediated degradation of p35 to p25 in postmortem human and rat brains, FEBS Lett, 489, 46, 10.1016/S0014-5793(00)02431-5 Taru, 2004, Facilitation of stress-induced phosphorylation of β-amyloid precursor protein family members by X11-like/Mint2 protein, J Biol Chem, 279, 21628, 10.1074/jbc.M312007200 Tomita, 1999, Interaction of a neuron-specific protein containing PDZ domains with Alzheimer’s amyloid precursor protein, J Biol Chem, 274, 2243, 10.1074/jbc.274.4.2243 Tseng, 2002, A survey of Cdk5 activator p35 and p25 levels in Alzheimer’s disease brains, FEBS Lett, 523, 58, 10.1016/S0014-5793(02)02934-4 Valtorta, 1989, Synaptophysin and synapsin I as tools for the study of the exo-endocytotic cycle, Cell Biol Int Rep, 13, 1023, 10.1016/0309-1651(89)90017-9 Yoo, 2001, p25 Protein in neuodegeneration, Nature, 411, 763, 10.1038/35081146