Cutaneous tissue repair: Basic biologic considerations. I

Williams, 1981, Mediation of increased vascular permeability after complement activation. Histamine independent action of C5a, J Exp Med, 153, 136, 10.1084/jem.153.1.136

Williams, 1973, Simultaneous measurement of local plasma exudation and blood flow changes induced by in- tradermal injection of vasoactive substances using l31I albumin and l33Xe, J Physiol (Lond), 246, 215

Brandstedt, 1980, Wound healing and formation of granulation tissue in normal and defi-brinogenated rabbits. An experimental model and histological study, Eur Surg Res, 12, 12, 10.1159/000128105

Ginsberg, 1981, Role of platelets in inflammation and rheumatic disease, Adv Inflam Res, 2, 53

Moncada, 1976, An enzyme isolated from arteries transforms prostaglandin endoperoxidases to an unstable substance that inhibits platelet aggregation, Nature, 263, 663, 10.1038/263663a0

Raz, 1977, Characterization of a novel metabolic pathway of arachidonate in coronary arteries which generates a potent endogenous coronary vasodilator, J Biol Chem, 252, 1123, 10.1016/S0021-9258(19)75215-6

Weksler, 1977, Synthesis of prostaglandin I2 (prostacyclin) by cultured human and bovine endothelial cells, Proc Natl Acad Sci USA, 74, 3922, 10.1073/pnas.74.9.3922

Lollar, 1980, Binding of thrombin to cultured human endothelial cells. Nonequilibrium aspects, J Biol Chem, 255, 10279, 10.1016/S0021-9258(19)70461-X

Baker, 1980, Proteasenexin. A cellular component that links thrombin and plasminogen activator and mediates their binding to cells, Cell, 21, 37, 10.1016/0092-8674(80)90112-9

Kisiel, 1977, Anticoagulant properties of bovine plasma protein C following activation by thrombin, Biochemistry, 16, 5824, 10.1021/bi00645a029

Esmon, 1981, Identification of an endothelial cell cofactor for tnrombin-catalyzed activation of protein C, Proc Natl Acad Sci USA, 78, 2249, 10.1073/pnas.78.4.2249

Binder, 1979, Purification and characterization of human vascular plasminogen activator derived from blood vessel perfusates, J Biol Chem, 254, 1998, 10.1016/S0021-9258(17)37756-6

Rijken, 1980, Relationship between tissue plaminogen activator and the activators in blood and vascular wall, Thromb Res, 18, 815, 10.1016/0049-3848(80)90204-2

Loskutoff, 1977, Synthesis of a fibrinolytic activator and inhibitor by endothelial cells, Proc Natl Acad Sci USA, 74, 3903, 10.1073/pnas.74.9.3903

Kaplan, 1983, Hageman factor—dependent pathways. Mechanism of initiation and bradykinin formation, Fed Proc, 42, 3123

Dvorak, 1985, Regulation of extravascular coagulation by microvascular permeability, Science, 227, 1059, 10.1126/science.3975602

Maynard, 1975, Association of tissue factor activity with the surface of cultured cells, J Clin Invest, 55, 814, 10.1172/JCI107992

Josso, 1965, Interaction of tissue factor and factor VII at the earliest phase of coagulation, Thromb Diath Haemorrh (Suppl), 17, 35

Marlar, 1982, An alternative extrinsic pathway of human blood coagulation, Blood, 60, 1353, 10.1182/blood.V60.6.1353.1353

Detwiler, 1973, Kinetics of the thrombin-induced release of calcium by platelets, Biochemistry, 12, 282, 10.1021/bi00726a017

Sixma, 1978, Platelet coagulant activities, Thromb Haemost, 40, 163, 10.1055/s-0038-1648647

Bode, 1981, The platelet membrane as a catalytic surface in thrombin generation. Availability of platelet factor I and platelet factor 3, Ann NY Acad Sci, 370, 348, 10.1111/j.1749-6632.1981.tb29747.x

Kaplan, 1971, A prealbumin activator of pre-kallikrein U. Derivation of activators of prekallikrein from active Hageman factor with plasmin, J Exp Med, 133, 696, 10.1084/jem.133.4.696

Habal, 1976, Generation of kinin by plasma kallikrein and plasmin, 23

Ghebrehiwet, 1981, Activation of classic pathway of complement by Hageman factor fragment, J Exp Med, 153, 665, 10.1084/jem.153.3.665

Craddock, 1977, Hemodialysis leukopenia: Pulmonary vascular leukostasis resulting from complement activation by dialyzer cellophane membrane, J Clin Invest, 59, 879, 10.1172/JCI108710

Snyderman, 1971, Biological activity of complement in vivo: Role of C5 in the accumulation of polymorphonuclear leukocytes in inflammatory exudates, J Exp Med, 134, 1131, 10.1084/jem.134.5.1131

Fernandez, 1978, Chemotactic response to human C3a and C5a anaphylatox-ins I. Evaluation of C3a and C5a leukotaxis in vitro and under simulated in vivo conditions, J Immunol, 120, 109, 10.4049/jimmunol.120.1.109

Snyderman, 1972, Human mononuclear leukocyte Chemotaxis: A quantitative assay for humoral and cellular chemotactic factors, J Immunol, 108, 857, 10.4049/jimmunol.108.3.857

Hugli, 1978, Anaphylatoxins, C3a and C5a, Adv Immunol, 26, 1, 10.1016/S0065-2776(08)60228-X

Stimler, 1982, Release of leukotrienes from guinea pig lung stimulated by C5a des Arg anaphylatoxin, J Immunol, 128, 2247, 10.4049/jimmunol.128.5.2247

McCarthy, 1979, Induction of lysosomal enzyme secretion by macrophages in response to the purified complement fragments C5a and C5a des Arg, J Immunol, 123, 2511, 10.4049/jimmunol.123.6.2511

Turk, 1976, A histochemical analysis of mononuclear cell infiltrates of the skin with particular reference to delayed hypersensitivity in the guinea pig, Int Arch Allergy Appl Immunol, 29, 278, 10.1159/000229709

Kaplan, 1972, A prealbumin activator of prekallikrein III. Appearance of chemotactic activity for human neutrophils by conversion of human prekallikrein to kallikrein, J Exp Med, 135, 81, 10.1084/jem.135.1.81

Gallin, 1974, Mononuclear cell chemotactic activity of kallikrein and plasminogen activator and its inhibition by CI inhibitor and α3-macroglobulin, J Immunol, 113, 1928, 10.4049/jimmunol.113.6.1928

Kay, 1973, Generation of che- motactic activity for leukocytes by the action of thrombin on human fibrinogen, Nature (NB), 243, 56

Stecher, 1972, The chemotactic activity of fibrin lysis products, Int Arch Allergy Appl Immunol, 43, 879, 10.1159/000230905

Ford-Hutchinson, 1980, Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes, Nature, 286, 264, 10.1038/286264a0

Freer, 1980, Further studies on the structural requirement for synthetic peptide che-moattractants, Biochemistry, 19, 2404, 10.1021/bi00552a019

Duel, 1981, Platelet factor 4 is chemotactic for neutrophils and monocytes, Proc Natl Acad Sci USA, 78, 4584, 10.1073/pnas.78.7.4584

Duel, 1982, Chemotaxis of monocytes and neutrophils to platelet-derived growth factor, J Clin Invest, 69, 1046, 10.1172/JCI110509

Postlethwaite, 1976, Collagen and collagen peptide-induced Chemotaxis of human blood monocytes, J Exp Med, 143, 1299, 10.1084/jem.143.6.1299

Senoir, 1980, Chemotactic activity of elastin-derived peptides, J Clin Invest, 66, 859, 10.1172/JCI109926

Nortis, 1982, Fibronectin fragments are chemotactic for human peripheral blood monocytes, J Immunol, 129, 1612, 10.4049/jimmunol.129.4.1612

Bar-Shavit, 1983, Chemotactic response of monocytes to thrombin, J Cell Biol, 96, 282, 10.1083/jcb.96.1.282

Leibovitch, 1975, The role of the macrophage in wound repair: A study with hydrocortisone and anti-macrophage serum, Am J Pathol, 78, 71

Fearon, 1978, Activation of the alternative complement pathway by E. coll: Resistance of bound C3b to inactivation by C3b INA and βIH, J Immunol, 120, 1772, 10.4049/jimmunol.120.5.1772.b

Fearon, 1977, Activation of the alternative complement pathway due to resistance of zymosan-bound amplification convertase to endogenous regulatory mechanisms, Proc Natl Acad Sci USA, 74, 1683, 10.1073/pnas.74.4.1683

Loose, 1979, Macrophage dysfunction after burn injury, Infect Immunol, 26, 157, 10.1128/IAI.26.1.157-162.1979

Newman, 1982, Phagocytosis of senescent neutrophils by human monocyte derived macrophages and rabbit inflammatory macrophages, J Exp Med, 156, 430, 10.1084/jem.156.2.430

Humes, 1977, Macrophages synthesize and release prostaglandins in response to inflammatory stimuli, Nature, 269, 149, 10.1038/269149a0

Rouzer, 1982, Secretion of leukotriene C and other arachidonic acid metabolites by mouse pulmonary macrophages, J Exp Med, 155, 720, 10.1084/jem.155.3.720

Tsukamoto, 1981, Macrophage production of fibronectin, a chemoattractant for fibroblasts, J Immunol, 127, 673, 10.4049/jimmunol.127.2.673

Leibovich, 1978, Production of macrophage-dependent fi-broblast-stimulating activity (M-FSA) by murine macrophages, Exp Cell Res, 113, 47, 10.1016/0014-4827(78)90086-1

Martin, 1981, Stimulation of nonlymphoid mesenchymal cell proliferation by a macrophage-derived growth factor, J Immunol, 126, 1510, 10.4049/jimmunol.126.4.1510

Lachman, 1983, Human interleukin I: Purification and properties, Fed Proc, 42, 2639

Schroff, 1981, Transglutaminase as a marker for subsets of murine macrophages, Eur J Immunol, 11, 637, 10.1002/eji.1830110809

Wahl, 1977, Prostaglandin regulation of macrophage collagenase production, Proc Natl Acad Sci USA, 74, 4955, 10.1073/pnas.74.11.4955

Werb, 1975, Secretion of a specific collagenase by stimulated macrophages, J Exp Med, 142, 346, 10.1084/jem.142.2.346

Werb, 1975, Elastase secretion by stimulated macrophages, J Exp Med, 142, 361, 10.1084/jem.142.2.361

Morland, 1977, Macrophage activation in vivo and in vitro, Exp Cell Res, 108, 279, 10.1016/S0014-4827(77)80035-9

Hunt, 1980

Winter, 1962, Formation of the scab and the rate of ep-ithelialization of superficial wounds in the skin of the young domestic pig, Nature, 193, 293, 10.1038/193293a0

Gabbiani, 1978, Cytoplasmic filaments and gap junctions in epithelial cells and myofibroblasts during wound healing, J Cell Biol, 76, 561, 10.1083/jcb.76.3.561

Hennings, 1980, Calcium regulation of growth and differentiation of mouse epidermal cells in culture, Cell, 19, 245, 10.1016/0092-8674(80)90406-7

Winter, 1972, Epidermal regeneration studied in the domestic pig

Krawczyk, 1971, A pattern of epidermal cell migration during wound healing, J Cell Biol, 49, 247, 10.1083/jcb.49.2.247

Hell, 1963, The effect of injury upon the uptake of 3H thymidine by guinea pig epidermis, Exp Cell Res, 31, 128, 10.1016/0014-4827(63)90162-9

Schwartz, 1982, Vessel wall growth control, 63

Cohen, 1962, Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening in the newborn animal, J Biol Chem, 237, 1555, 10.1016/S0021-9258(19)83739-0

Cohen, 1965, The stimulation of epidermal proliferation by a specific protein (EGF), Dev Biol, 12, 394, 10.1016/0012-1606(65)90005-9

Carpenter, 1979, Rapid enhancement of protein phosphorylation in A-431 cell membrane preparation by epidermal growth factor, J Biol Chem, 254, 4884, 10.1016/S0021-9258(17)30094-7

Stanley, 1981, Detection of basement membrane zone antigens during epidermal wound healing in pigs, J Invest Dermatol, 77, 240, 10.1111/1523-1747.ep12480082

Clark, 1982, Fibronectin and fibrin provide a provisional matrix for epidermal cell migration during wound reepithelialization, J Invest Dermatol, 70, 264, 10.1111/1523-1747.ep12500075

Repesh, 1982, Fibronectin involvement in granulation tissue and wound healing in rabbits, J Histochem Cytochem, 30, 351, 10.1177/30.4.6174568

Donaldson, 1983, Fibrinogen and fibronectin as substrates for epidermal cell migration during wound closure, J Cell Sci, 62, 117, 10.1242/jcs.62.1.117

Odland, 1968, Human wound repair. I. Epidermal regeneration, J Cell Biol, 39, 135, 10.1083/jcb.39.1.135

Stenn, 1979, Migrating epidermis produces ABi collagen and requires continued collagen synthesis for movement, Nature, 277, 229, 10.1038/277229a0

Clark, 1983, Fibronectin beneath reepithelializing epidermis in vivo: Sources and significance, J Invest Dermatol, 80, 26, 10.1038/jid.1983.7

Kariniemi, 1982, Cytoskeleton and pericellular matrix organization of pure adult human keratinocytes cultured from suction-blister roof epidermis, J Cell Sci, 58, 49, 10.1242/jcs.58.1.49

O’Keefe, 1984, Production of soluble and cell-associated fibronectin by cultured keratinocytes, J Invest Dermatol, 82, 150, 10.1111/1523-1747.ep12259708

Kubo, 1984, Human keratinocytes synthesize, secrete and deposit fibronectin in the pericellular matrix, J Invest Dermatol, 82, 580, 10.1111/1523-1747.ep12261325

Donoff, 1971, Preparation and properties of collagenases from epithelium and mesenchyme of healing mammalian wounds, Biochim Biophys Acta, 227, 639, 10.1016/0005-2744(71)90014-3

Isseroff, 1982, Plasminogen activator in differentiating mouse keratinocytes, J Invest Dermatol, 80, 217, 10.1111/1523-1747.ep12534464

Takashima, 1984, Human keratinocyte adhesion and phagocytosis promoted by fibronectin, J Invest Dermatol, 83, 352, 10.1111/1523-1747.ep12264522

Hinter, 1980, Expression of basement membrane zone antigens at the dermo-epibolic function in organ culture of human skin, J Invest Dermatol, 74, 200, 10.1111/1523-1747.ep12541715

Krawczyk, 1973, Hemidesmosome and des-mosome morphogenesis during epidermal wound healing, J Ultrastruct Res, 45, 93, 10.1016/S0022-5320(73)90035-X

Gipson, 1983, Hemidesmosome formation in vitro, J Cell Biol, 97, 849, 10.1083/jcb.97.3.849

Mayno, 1979, The story of the myofibroblasts, Am Surg Pathol, 3, 535, 10.1097/00000478-197912000-00006

Gabbiani, 1979, The role of contractile proteins in wound healing and fibrocontractive disease, Methods Achiev Exp Pathol, 9, 187

Gospodarowicz, 1975, Purification of fibroblast growth factor from bovine pituitary, J Biol Chem, 250, 2515, 10.1016/S0021-9258(19)41631-1

Zetter, 1976, Effects of protease treatment on growth, morphology, adhesion, and cell surface proteins of secondary chick embryo fibroblasts, Cell, 7, 407, 10.1016/0092-8674(76)90170-7

Pohjanpelto, 1978, Stimulation of DNA synthesis in human fibroblasts by thrombin, J Cell Physiol, 95, 189, 10.1002/jcp.1040950208

Glenn, 1979, Thrombin-stimulated cell division involves proteolysis of its cell surface receptor, Nature, 278, 711, 10.1038/278711a0

Hall, 1980, Differential effects of thrombin on growth of human fibroblasts, J Cell Biol, 85, 70, 10.1083/jcb.85.1.70

Liebovich, 1976, A macrophage dependent factor that stimulates the proliferation of fibroblasts in vitro, Am J Pathol, 84, 501

Heldin, 1979, Platelet-derived growth factor: Purification and partial characterization, Proc Natl Acad Sci USA, 76, 3722, 10.1073/pnas.76.8.3722

Vogel, 1980, Role of serum components in density-dependent inhibition of growth of cells in culture: Platelet-derived growth factor is the major-serum determinant of saturation density, J Cell Biol, 85, 377, 10.1083/jcb.85.2.377

Antoniades, 1983, Human platelet-derived growth factor: Structure and function, Fed Proc, 42, 2630

Carpenter, 1976, 125I-labeled human epidermal growth factor (hEGF): Binding, internalization, and degradation in human fibroblasts, J Cell Biol, 71, 159, 10.1083/jcb.71.1.159

Rinderknecht, 1976, Polypeptides with non-suppressible insulin-like and cell-growth promoting activities in human serum: Isolation, chemical characterization and some biological properties of forms I and II, Proc Natl Acad Sci USA, 73, 2365, 10.1073/pnas.73.7.2365

Adams, 1983, Developmental patterns of insulin-like growth factor-I and -II synthesis and regulation in rat fibroblasts, Nature, 302, 150, 10.1038/302150a0

Oppenheimer, 1983, Insulin action rapidly modulates the apparent affinity of the insulin-like growth factor II receptor, J Biol Chem, 258, 4824, 10.1016/S0021-9258(18)32499-2

Assoian, 1983, Transforming growth factor-β in human platelets: Identification of a major storage site, purification, and characterization, J Biol Chem, 258, 7155, 10.1016/S0021-9258(18)32345-7

Assoian, 1984, Transforming growth factor-β controls receptor levels for epidermal growth factor in NRK fibroblasts, Cell, 36, 35, 10.1016/0092-8674(84)90071-0

Postlethwaite, 1976, Chemotactic attraction of human fibroblasts to a lymphocyte-derived factor, J Exp Med, 144, 1188, 10.1084/jem.144.5.1188

Postlethwaite, 1978, Chemotactic attraction of human fibroblasts to type I, II and III col-lagens and collagen-derived peptides, Proc Natl Acad Sci USA, 75, 871, 10.1073/pnas.75.2.871

Postlethwaite, 1979, Generation of a fibroblast chemotactic factor in serum by activation of complement, J Clin Invest, 64, 1379, 10.1172/JCI109595

Gauss-Muller, 1980, Role of attachment factors and attractants in fibroblast Chemotaxis, J Lab Clin Med, 96, 1071

Postlethwaite, 1981, Induction of fibroblast Chemotaxis by fibronectin: Localization of the chemotactic region to a 140,000 molecular weight non-gelatin binding fragment, J Exp Med, 153, 494, 10.1084/jem.153.2.494

Seppa, 1982, The platelet-derived growth factor is a chemoattractant for fibroblasts, J Cell Biol, 92, 584, 10.1083/jcb.92.2.584

Abercrombie, 1971, The locomotion of fibroblasts in culture. IV. Electron microscopy of the leading lamella, Exp Cell Res, 67, 359, 10.1016/0014-4827(71)90420-4

Bellows, 1982, Fibroblasts contracting three-dimensional collagen gels exhibit ultrastructure consistent with either contraction or protein secretion, J Ultrastruct Res, 78, 178, 10.1016/S0022-5320(82)80022-1

Wrann, 1980, Modulation of epidermal growth factor receptors on 3T3 cells by platelet-derived growth factor, Science, 210, 1363, 10.1126/science.6254158

Bowen-Pope, 1983, Interactions between receptors for platelet-derived growth factor and epidermal growth factor, J Cell Physiol, 96, 679

Stiles, 1979, Dual control of cell growth by somatomedins and platelet-derived growth factor, Proc Natl Acad Sci USA, 76, 1279, 10.1073/pnas.76.3.1279

Rozengurt, 1982, Inhibition of epidermal growth factor binding to mouse cultured cells by fibroblast-derived growth factor, J Biol Chem, 257, 3680, 10.1016/S0021-9258(18)34834-8

Clemmons, 1980, Sequential addition of platelet factor and plasma to Balb/c 3T3 fibroblast cultures stimulates somatomedin-C binding early in cell cycle, Proc Natl Acad Sci USA, 77, 6644, 10.1073/pnas.77.11.6644

Grotendorst, 1984, Alteration of the chemotactic response of NIH/3T3 cells to PDGF by growth factors, transformation and tumor promoters, Cell, 36, 279, 10.1016/0092-8674(84)90221-6

Kurkinen, 1980, Sequential appearance of fibronectin and collagen in experimental granulation tissue, Lab Invest, 43, 47

Grinnell, 1981, Distribution of fibronectin during wound healing in vivo, J Invest Dermatol, 76, 181, 10.1111/1523-1747.ep12525694

Yamada, 1978, Fibronectin-adhesive glycoproteins of cell surface and blood, Nature, 275, 179, 10.1038/275179a0

Mosher, 1978, Thrombin stimulates the production and release of a major surface-associated glycoprotein (fibronectin) in cultures of human fibroblasts, Exp Cell Res, 112, 323, 10.1016/0014-4827(78)90215-X

Chen, 1977, Control of a cell surface major glycoprotein by epidermal growth factor, Science, 197, 776, 10.1126/science.302030

Klebe, 1974, Isolation of a collagen-dependent cell attachment factor, Nature, 250, 248, 10.1038/250248a0

Pearlstein, 1976, Plasma membrane glycoprotein which mediates adhesion of fibroblasts to collagen, Nature, 262, 497, 10.1038/262497a0

Grinnell, 1980, Fibroblast adhesion to fibrinogen and fibrin substrate: Requirement for cold-insoluble globulin (plasma fibronectin), Cell, 19, 517, 10.1016/0092-8674(80)90526-7

Carter, 1965, Principles of cell motility: The direction of cell movement and cancer invasion, Nature, 208, 1183, 10.1038/2081183a0

Ali, 1978, Effect of LETS glycoprotein on cell motility, Cell, 14, 439, 10.1016/0092-8674(78)90129-0

Hsieh, 1983, Behavior of cells seeded in isolated fibronectin matrices, J Cell Biol, 96, 1208, 10.1083/jcb.96.5.1208

Majno, 1971, Contraction of granulation tissue in vitro: Similarity to smooth muscle, Science, 173, 548, 10.1126/science.173.3996.548

Ryan, 1974, Myofibroblasts in human granulation tissue, Hum Pathol, 5, 55, 10.1016/S0046-8177(74)80100-0

Gabbiani, 1972, Granulation tissue as a contractile organ: A study of structure and function, J Exp Med, 135, 719, 10.1084/jem.135.4.719

Singer, 1979, The fibronexus: A transmembrane association of fibronectin-containing fibers and bundles of 5 nm filaments in hamster and human fibroblasts, Cell, 16, 675, 10.1016/0092-8674(79)90040-0

Furcht, 1980, An axial periodic fibrillar arrangement of antigenic determinants for fibronectin and procollagen on ascor-bate-treated human fibroblasts, J Supramol Struct, 13, 15, 10.1002/jss.400130103

Singer, 1981, A transmembrane relationship between fibronectin and vinculin (130 kd protein): Serum modulation in normal and transformed hamster fibroblasts, Cell, 24, 481, 10.1016/0092-8674(81)90339-1

Singer, 1984, In vivo co-distribution of fibronectin and actin fibers in granulation tissue: Immunofluorescence and electron microscope studies of the fibronexus at the myofibroblast surface, J Cell Biol, 98, 2091, 10.1083/jcb.98.6.2091

Bell, 1979, Production of a tissuelike structure by contraction of collagen lattices by human fibroblasts of different proliferative potential in vitro, Proc Natl Acad Sci USA, 76, 1274, 10.1073/pnas.76.3.1274

Bell, 1981, Living tissue formed in vitro and accepted as skin-equivalent tissue of full thickness, Science, 211, 1052, 10.1126/science.7008197

Bell, 1983, The reconstitution of living skin, J Invest Dermatol, 81, 2, 10.1111/1523-1747.ep12539993

Ausprunk, 1977, Migration arid proliferation of endothelial cells in preformed and newly formed blood vessels during tumor angiogenesis, Microvasc Res, 14, 53, 10.1016/0026-2862(77)90141-8

Rifkin, 1982, Proteases and angiogenesis: Production of plasminogen activation and collagenase by endothelial cells, 191

Kalebic, 1983, Basement membrane collagen: degradation by migrating endothelial cells, Science, 221, 281, 10.1126/science.6190230

Sholley, 1978, The effects of leukocyte depletion on corneal neovascularization, Lab Invest, 38, 32

Folkman, 1982, Angiogenesis: Initiation and control, Ann NY Acad Sci, 401, 212, 10.1111/j.1749-6632.1982.tb25720.x

Folkman, 1974, Tumor angiogenesis, Adv Cancer Res, 19, 331, 10.1016/S0065-230X(08)60058-5

Polverini, 1977, Activated macrophages induce vascular proliferation, Nature, 269, 804, 10.1038/269804a0

Sidky, 1975, Lymphocyte-induced angiogenesis A quantitative and sensitive assay of the graft-vs-host reaction, J Exp Med, 141, 1084, 10.1084/jem.141.5.1084

Brown, 1980, Angiogenic factor from synovial fluid resembling that from tumors, Lancet, 1, 682, 10.1016/S0140-6736(80)91173-3

D’Amore, 1981, Angiogenic activity from bovine retina: Partial purification and characterization, Proc Natl Acad Sci USA, 78, 3068, 10.1073/pnas.78.5.3068

Frederick, 1984, Initiation of angiogenesis by human follicular fluid, Science, 224, 389, 10.1126/science.6200930

Wolf, 1973, Demonstration and characterization of a epidermal angiogenic factor, J Invest Dermatol, 61, 130, 10.1111/1523-1747.ep12676198

Banda, 1982, Isolation of a nonmitogenic angiogenesis factor from wound fluid, Proc Natl Acad Sci USA, 79, 7773, 10.1073/pnas.79.24.7773

Remensnyder, 1968, Oxygen gradients in healing wounds, Am J Pathol, 52, 301

Imre, 1964, Studies on the mechanism of retinal neovascularization: Role of lactic acid, Br J Ophthalmol, 48, 75, 10.1136/bjo.48.2.75

Zauberman, 1969, Stimulation of neovascularization of the cornea by biogenic amines, Exp Eye Res, 8, 77, 10.1016/S0014-4835(69)80083-7

Haudenschild, 1976, Human vascular endothelial cells in culture: Lack of response to serum growth factors, Exp Cell Res, 98, 175, 10.1016/0014-4827(76)90477-8

Gospodarowicz, 1977, Control of proliferation of bovine vascular endothelial cells, J Cell Physiol, 91, 377, 10.1002/jcp.1040910307

Wall, 1978, Factors influencing endothelial cell proliferation in vitro, J Cell Physiol, 96, 203, 10.1002/jcp.1040960209

Clemmons, 1983, Dialyzable factor in human serum of platelet origin stimulates endothelial cell replication and growth, Proc Natl Acad Sci USA, 80, 1641, 10.1073/pnas.80.6.1641

King, 1984, Characterization and partial purification of an endothelial cell growth factor from human platelets, J Clin Invest, 73, 392, 10.1172/JCI111224

Gospodarowicz, 1978, Control of proliferation of human vascular endothelial cells: Characterization of the response of human umbilical vein endothelial cells to fibroblast growth factor, epidermal growth factor, and thrombin, J Cell Biol, 77, 774, 10.1083/jcb.77.3.774

Gospodarowicz, 1983, Bovine brain and pituitary fibroblast growth factors: Comparison of their abilities to support the proliferation of human and bovine vascular endothelial cells, J Cell Biol, 97, 1677, 10.1083/jcb.97.6.1677

Maciag, 1982, High and low molecular weight forms of endothelial cell growth factor, J Biol Chem, 257, 5333, 10.1016/S0021-9258(19)83778-X

Maciag, 1984, Heparin binds endothelial cell growth factor, the principal endothelial cell mitogen in bovine brain, Science, 225, 932, 10.1126/science.6382607

Glazer, 1980, Adult tissues contain chemoattractants for vascular endothelial cells, Nature, 288, 483, 10.1038/288483a0

Bowersox, 1982, Chemotaxis of aortic endothelial cells in response to fibronectin, Cancer Res, 42, 2547

Wall, 1978, Human endothelial cell migration: Stimulated by a released platelet factor, Lab Invest, 39, 523

Azizkhan, 1980, Mast cell heparin stimulates migration of capillary endothelial cells in vitro, J Exp Med, 152, 931, 10.1084/jem.152.4.931

Bernstein, 1982, Migration of cultured vascular cells in response to plasma and platelet-derived factors, J Cell Sci, 56, 71, 10.1242/jcs.56.1.71

Raju, 1984, Characterization of a chemoattractant for endothelium induced by angiogenesis effectors, Cancer Res, 44, 1579

Madri, 1982, Aortic endothelial cell migration. I. Matrix requirements and composition, Am J Pathol, 106, 180

Clark, 1982, Blood vessel fibronectin increases in conjunction with endothelial cell proliferation and capillary ingrowth during wound healing, J Invest Dermatol, 79, 269, 10.1111/1523-1747.ep12500076

Clark, 1982, Fibronectin is produced by blood vessels in response to injury, J Exp Med, 156, 646, 10.1084/jem.156.2.646

Jaffe, 1978, Synthesis of fibronectin by cultured human endothelial cells, J Exp Med, 147, 1779, 10.1084/jem.147.6.1779

Macarak, 1978, Synthesis of cold-insoluble globulin by cultured calf endothelial cells, Proc Natl Acad Sci USA, 75, 2621, 10.1073/pnas.75.6.2621

Birdwell, 1978, Identification, localization, and role of fibronectin in cultured bovine endothelial cells, Proc Natl Acad Sci USA, 75, 3273, 10.1073/pnas.75.7.3273

Ausprunk, 1981, Proteoglycans in the microvasculature. II. Histochemical localization in proliferating capillaries of the rabbit cornea, Am J Pathol, 103, 367

Delvos, 1982, Interaction of vascular wall cells with collagen gels, Lab Invest, 46, 61

Madri, 1983, Capillary endothelial cell cultures: Phenotypic modulation by matrix components, J Cell Biol, 97, 153, 10.1083/jcb.97.1.153

Tseng, 1983, Modulation of collagen synthesis by a growth factor and by the extracellular matrix: Comparison of cellular response to two different stimuli, J Cell Biol, 97, 803, 10.1083/jcb.97.3.803

Montesano, 1983, In vitro organization of endothelial cells into capillary networks is promoted by collagen matrices, J Cell Biol, 97, 1648, 10.1083/jcb.97.5.1648

Schor, 1983, Effects of culture conditions on the proliferation, morphology and migration of bovine aortic endothelial cells, J Cell Sei, 62, 267, 10.1242/jcs.62.1.267

Ausprunk, 1978, The sequence of events in the regression of corneal capillaries, Lab Invest, 38, 284

Hynes, 1982, Fibronectins: Multifunctional modular glycoproteins, J Cell Biol, 95, 369, 10.1083/jcb.95.2.369

Bornstein, 1977, Cell surface-associated structural proteins in connective tissue cells, Proc Natl Acad Sei USA, 74, 2480, 10.1073/pnas.74.6.2480

Vaheri, 1978, Codistribution of pericellular matrix proteins in cultured fibroblasts and loss in transformation: Fibronectin and procollagen, Proc Natl Acad Sei USA, 75, 4944, 10.1073/pnas.75.10.4944

Hayman, 1982, Codistribution of heparan sulfate proteoglycan, laminin, and fibronectin in the extracellular matrix of normal rat kidney cells, J Cell Biol, 94, 28, 10.1083/jcb.94.1.28

Hedman, 1982, Structure of the pericellular matrix: Association of heparan and chondroitin sulfates with fibronectin-procollagen fibers, Cell, 28, 663, 10.1016/0092-8674(82)90221-5

McDonald, 1982, Role of fibronectin in collagen deposition: Fab' antibodies to the gelatin-binding domain of fibronectin inhibits both fibronectin and collagen organization in fibroblast extracellular matrix, J Cell Biol, 92, 485, 10.1083/jcb.92.2.485

Chen, 1978, Studies on intracellular LETS glycoprotein matrices, Cell, 14, 377, 10.1016/0092-8674(78)90123-X

Keski-Oja, 1981, Thrombin affects fibronectin and procollagen in the pericellular matrix of cultured human fibroblasts, Biochim Biophys Acta, 673, 323, 10.1016/0304-4165(81)90463-3

Holund, 1982, Fibronectin in experimental granulation tissue, Acta Pathol Microbiol Immunol Scand, 90, 159

Viljanto, 1981, Fibronectin in early phases of wound healing in children, Acta Chir Scand, 147, 7

Furthmayr, 1982, The use of antibodies to connective tissue proteins in studies on their location in tissue, vol. II, 89

Epstein, 1974, [α1,(III)]3 human skin collagen: Release by pepsin digestion and preponderance in fetal life, J Biol Chem, 249, 3225, 10.1016/S0021-9258(19)42661-6

Clore, 1979, Quantitation of collagen types I and III during wound healing in rat skin, Proc Soc Exp Biol Med, 161, 337, 10.3181/00379727-161-40548

Gay, 1978, Collagen types in early phases of wound healing in children, Acta Chir Scand, 144, 205

Balian, 1979, Isolation of a collagen-binding fragment from fibronectin and cold-insoluble globulin, J Biol Chem, 254, 1429, 10.1016/S0021-9258(17)37782-7

McDonald, 1980, Degradation of fibronectin by human leukocyte elastase, J Biol Chem, 255, 8848, 10.1016/S0021-9258(18)43580-6

Vartio, 1981, Susceptibility of soluble and matrix fibronectins to degradation by tissue proteinases, mast cell chymase and cathepsin, J Biol Chem, 256, 471, 10.1016/S0021-9258(19)70161-6

Furie, 1980, Proteolytically derived fragments of human plasma fibronectin and their localization within intact molecule, J Biol Chem, 365, 3134, 10.1016/S0021-9258(19)85862-3

Silbert, 1982, Structure and metabolism of proteoglycans and glycosaminoglycans, J Invest Dermatol, 79, 31, 10.1111/1523-1747.ep12545094

Hascall, 1981, Proteoglycans, 39

Balazs, 1950, The basic dye-uptake and the presence of growth inhibiting substance in the healing tissue of skin wounds, Exp Cell Res, 1, 206, 10.1016/0014-4827(50)90033-4

Bently, 1967, Rate of chondroitin sulfate formation in wound healing, Ann Surg, 165, 186, 10.1097/00000658-196702000-00004

Dorner, 1967, Glycosaminoglycans of regenerating tendon, Arthritis Rheum, 10, 275

Anseth, 1961, Glycosaminoglycans in corneal regeneration, Exp Eye Res, 1, 122, 10.1016/S0014-4835(61)80017-1

Toole, 1971, The extracellular matrix of the regenerating newt limb: Synthesis and removal of hyal-uronate prior to differentiation, Dev Biol, 25, 57, 10.1016/0012-1606(71)90019-4

Toole, 1971, Hyaluronate production and removal during corneal development in the chick, Dev Biol, 26, 28, 10.1016/0012-1606(71)90104-7

Toole, 1972, Hyaluronate turnover during chondrogenesis in the developing chick limb and axial skeleton, Dev Biol, 29, 321, 10.1016/0012-1606(72)90071-1

Toole, 1981, Glycosaminoglycans in morphogenesis, 259

Culp, 1979, Fibronectin and proteoglycans as determinants of cell-substratum adhesion, J Supramol Struct, 11, 401, 10.1002/jss.400110314

Lark, 1985, Close and focal contact adhesions of fibroblasts to fibronectin-containing matrix, Fed Proc, 44, 394

Rollins, 1979, Glycosaminoglycans in the substrate adhesion sites of normal and virus-transformed murine cells, Biochemistry, 18, 141, 10.1021/bi00568a022

Tomida, 1974, Hyaluronic acid synthetase in cultured mammalian cells producing hyaluronic acid: Oscillatory change during the growth phase and suppression by 5-bromodeoxyuridine, Biochim Biophys Acta, 338, 352, 10.1016/0304-4165(74)90295-5

Cohn, 1976, Relationship of transformation, cell density and growth control to cellular distribution of newly synthesized glycosaminoglycan, J Cell Biol, 71, 280, 10.1083/jcb.71.1.280

Underhill, 1976, Density-dependent changes in the amount of sulfated glycosaminoglycans associated with mouse 3T3 cells, J Cell Physiol, 89, 53, 10.1002/jcp.1040890106

Hopwood, 1977, Glycosaminoglycan synthesis by cultured human skin fibroblasts after transformation with simian virus 40, J Biol Chem, 252, 4777, 10.1016/S0021-9258(17)40123-2

Tomida, 1975, Induction of hyaluronic acid synthetase activity in rat fibroblasts by medium change of confluent cultures, J Cell Physiol, 86, 121, 10.1002/jcp.1040860114

Moscatelli, 1975, Increased hyaluronic acid production on stimulation of DNA synthesis in chick embryo fibroblasts, Nature, 254, 65, 10.1038/254065a0

Lembach, 1976, Enhanced synthesis and extracellular accumulation of hyaluronic acid during stimulation of quiescent human fibroblasts by mouse epidermal growth factor, J Cell Physiol, 89, 277, 10.1002/jcp.1040890211

Bertolami, 1982, Identification characterization, and partial purification of mammalian skin wound hyaluronidase, J Invest Dermatol, 79, 417, 10.1111/1523-1747.ep12530400

Wood, 1960, The formation of fibrils from collagen solutions: Effect of chondroitin sulfate and other naturally occurring polyanions on the rate of formation, Biochem J, 75, 605, 10.1042/bj0750605

Armitage, 1971, New fibrous long spacing form of collagen, Nature (NB), 229, 151

Kischer, 1974, Collagen and mucopolysaccharides in the hypertrophic scar, Connect Tissue Res, 2, 205, 10.3109/03008207409152245

Shetlar, 1972, The hypertrophic scar: Hexosarnine-containing components of bum scars, Proc Soc Exp Biol Med, 139, 544, 10.3181/00379727-139-36182

Kraemer, 1972, Cell-cycle dependent desquamation of heparan sulfate from the cell surface, J Cell Biol, 55, 713, 10.1083/jcb.55.3.713

Castellot, 1981, Vascular endothelial cells produce a heparin-like inhibitor of smooth muscle growth, J Cell Biol, 90, 372, 10.1083/jcb.90.2.372

Letourneau, 1980, The regulation of cell behavior by cell adhesion, vol, 2, 339

Grobstein, 1967, Mechanisms of organogenetic tissue interaction, Natl Cancer Inst Monogr, 26, 279

Bernfield, 1972, Acid mucopolysaccharide (glycosaminoglycan) at the epithelial-mesenchymal interface of mouse embryo salivary glands, J Cell Biol, 52, 664, 10.1083/jcb.52.3.664

Trelstad, 1974, Epithelial collagen and glycosaminoglycans in the embryonic cornea: Macromolecular order and morphogenesis in the basement membranes, J Cell Biol, 62, 815, 10.1083/jcb.62.3.815

Hay, 1974, Glycosaminoglycan synthesis by embryonic inductors: Neural tube, notocord, and lens, J Cell Biol, 62, 889, 10.1083/jcb.62.3.889

Bernfield, 1972, Dependence of salivary epithelial morphology and branching morphogenesis upon acid mucopolysaccharide-protein (proteoglycan) at the epithelial surface, J Cell Biol, 52, 647, 10.1083/jcb.52.3.674

Banerjee, 1977, Basal lamina of embryonic salivary epithelial: Production by the epithelium and role in maintaining lobular morphology, J Cell Biol, 73, 445, 10.1083/jcb.73.2.445

Cohn, 1977, Basal lamina of embryonic salivary epithelia: Nature of glycosaminoglycan and organization of extracellular materials, J Cell Biol, 73, 464, 10.1083/jcb.73.2.464

Gordon, 1980, The basal lamina of the postnasal mammary epithelium contains glycosaminoglycans in a precise ultrastructural organization, Dev Biol, 74, 118, 10.1016/0012-1606(80)90056-1

Quinter, 1982, Proteoglycan modifications by granulation tissue in culture, Expl Cell Biol, 50, 222

Prockop, 1977, Collagen diseases and the biosynthesis of collagen, Hosp Pract, 12, 62, 10.1080/21548331.1977.11707242

Burgeson, 1982, Genetic heterogeneity of collagens, J Invest Dermatol, 79, 25, 10.1111/1523-1747.ep12544829

Sage, 1982, Collagens of basement membranes, J Invest Dermatol, 79, 51, 10.1111/1523-1747.ep12545773

Trelstad, 1981, Matrix assembly, 179

Timpl, 1981, A network model for the organization of type IV collagen molecules in basement membranes, Eur J Biochem, 120, 203, 10.1111/j.1432-1033.1981.tb05690.x

Gay, 1981, Collagen molecules comprised of 1 (V)-chains (B chains): An apparent localization in the exocytoskeleton, Cell Res, 1, 53, 10.1016/S0174-173X(80)80007-0

Chung, 1974, Collagen polymorphism: Characterization of molecules with the chain composition α1(III)3, Science, 183, 1200, 10.1126/science.183.4130.1200

Gabbiani, 1976, Collagen and myofibroblasts of granulation tissue: A chemical, ultra-structural and immunologic study, Virchows Arch (Cell Pathol), 21, 133, 10.1007/BF02899150

Hering, 1983, Type V collagen during granulation tissue development, Exp Mol Pathol, 39, 219, 10.1016/0014-4800(83)90053-9

Ehrlich, 1981, The identification of αA and αB collagen chains in hypertrophic scars, Exp Mol Pathol, 34, 1, 10.1016/0014-4800(81)90030-7

Levenson, 1965, The healing of rat skin wounds, Ann Surg, 161, 293, 10.1097/00000658-196502000-00019

Gabbiani, 1976, Collagen and myofibroblasts of granulation tissue: A chemical, ultra-structural and immunologic study, Virchows Arch (Cell Pathol), 21, 133, 10.1007/BF02899150

Abercrombie, 1954, Collagen formation and wound contraction during repair of small excised wounds in the skin of rats, J Embryol Exp Morphol, 2, 264

Madden, 1968, Studies on the biology of collagen during wound healing. I. Rate of collagen synthesis and deposition in cutaneous wounds of the rat, Surgery, 64, 288

Bailey, 1975, Characterization of the collagen of human hypertrophic and normal scars, Biochim Biophys Acta, 405, 412, 10.1016/0005-2795(75)90106-3

Diegelmann, 1975, Measurement of collagen biosynthesis during wound healing, J Surg Res, 19, 239, 10.1016/0022-4804(75)90087-6

Barnes, 1975, Studies on collagen synthesis in the mature dermal scar in the guinea pig, 3, 917

Lazarus, 1968, Degradation of collagen by a human granulocyte collagen-olytic system, J Clin Invest, 47, 2622, 10.1172/JCI105945

Robertson, 1972, Collagenase: Localization in polymorphonuclear leukocyte granules in the rabbit, Science, 177, 64, 10.1126/science.177.4043.64

Sugrue, 1981, Response of basal epithelial cell surface and cytoskeleton to solubilized extracellular matrix molecules, J Cell Biol, 91, 45, 10.1083/jcb.91.1.45