Current themes in neuroimaging of epilepsy: Brain networks, dynamic phenomena, and clinical relevance

Clinical Neurophysiology - Tập 121 - Trang 1153-1175 - 2010
Mark Richardson1
1P043 Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK

Tài liệu tham khảo

Abbott, 2009, Voxel-based iterative sensitivity (VBIS) analysis: methods and a validation of intensity scaling for T2-weighted imaging of hippocampal sclerosis, Neuroimage, 44, 812, 10.1016/j.neuroimage.2008.09.055 Abou-Khalil, 2007, An update on determination of language dominance in screening for epilepsy surgery: the Wada test and newer noninvasive alternatives, Epilepsia, 48, 442, 10.1111/j.1528-1167.2007.01012.x Aghakhani, 2004, FMRI activation during spike and wave discharges in idiopathic generalized epilepsy, Brain, 127, 1127, 10.1093/brain/awh136 Aghakhani, 2006, Cortical and thalamic fMRI responses in partial epilepsy with focal and bilateral synchronous spikes, Clin Neurophysiol, 117, 177, 10.1016/j.clinph.2005.08.028 Akhtari, 2008, Functionalized magnetonanoparticles for MRI diagnosis and localization in epilepsy, Epilepsia, 49, 1419, 10.1111/j.1528-1167.2008.01615.x Aljabar, 2008, Automated morphological analysis of magnetic resonance brain imaging using spectral analysis, Neuroimage, 43, 225, 10.1016/j.neuroimage.2008.07.055 Allen, 2008, Effects of spatial transformation on regional brain volume estimates, Neuroimage, 42, 535, 10.1016/j.neuroimage.2008.05.047 Ances, 2008, Regional differences in the coupling of cerebral blood flow and oxygen metabolism changes in response to activation: implications for BOLD-fMRI, Neuroimage, 39, 1510, 10.1016/j.neuroimage.2007.11.015 Araujo, 2006, Volumetric evidence of bilateral damage in unilateral mesial temporal lobe epilepsy, Epilepsia, 47, 1354, 10.1111/j.1528-1167.2006.00605.x Archer, 2003, FMRI “deactivation” of the posterior cingulate during generalized spike and wave, Neuroimage, 20, 1915, 10.1016/S1053-8119(03)00294-5 Ashburner, 2000, Voxel-based morphometry – the methods, Neuroimage, 11, 805, 10.1006/nimg.2000.0582 Barnes, 2008, A comparison of methods for the automated calculation of volumes and atrophy rates in the hippocampus, Neuroimage, 40, 1655, 10.1016/j.neuroimage.2008.01.012 Bartolomei, 2005, Entorhinal cortex involvement in human mesial temporal lobe epilepsy: an electrophysiologic and volumetric study, Epilepsia, 46, 677, 10.1111/j.1528-1167.2005.43804.x Bauer, 2006, Transient and permanent magnetic resonance imaging abnormalities after complex partial status epilepticus, Epilepsy Behav, 8, 666, 10.1016/j.yebeh.2006.01.002 Bell, 2009, Epilepsy surgery outcomes in temporal lobe epilepsy with a normal MRI, Epilepsia, 50, 2053, 10.1111/j.1528-1167.2009.02079.x Benedek, 2006, Longitudinal changes in cortical glucose hypometabolism in children with intractable epilepsy, J Child Neurol, 21, 26, 10.1177/08830738060210011101 Benedek, 2004, Metabolic changes of subcortical structures in intractable focal epilepsy, Epilepsia, 45, 1100, 10.1111/j.0013-9580.2004.43303.x Benke, 2006, Language lateralization in temporal lobe epilepsy: a comparison between fMRI and the Wada Test, Epilepsia, 47, 1308, 10.1111/j.1528-1167.2006.00549.x Berl, 2005, Seizure focus affects regional language networks assessed by fMRI, Neurology, 65, 1604, 10.1212/01.wnl.0000184502.06647.28 Bernasconi, 2003, Entorhinal cortex MRI assessment in temporal, extratemporal, and idiopathic generalized epilepsy, Epilepsia, 44, 1070, 10.1046/j.1528-1157.2003.64802.x Bernasconi, 2003, Mesial temporal damage in temporal lobe epilepsy: a volumetric MRI study of the hippocampus, amygdala and parahippocampal region, Brain, 126, 462, 10.1093/brain/awg034 Bernasconi, 2004, Whole-brain voxel-based statistical analysis of gray matter and white matter in temporal lobe epilepsy, Neuroimage, 23, 717, 10.1016/j.neuroimage.2004.06.015 Bernasconi, 2005, Progression in temporal lobe epilepsy: differential atrophy in mesial temporal structures, Neurology, 65, 223, 10.1212/01.wnl.0000169066.46912.fa Bernhardt, 2009, Thalamo-cortical network pathology in idiopathic generalized epilepsy: insights from MRI-based morphometric correlation analysis, Neuroimage, 46, 373, 10.1016/j.neuroimage.2009.01.055 Bernhardt, 2008, Mapping limbic network organization in temporal lobe epilepsy using morphometric correlations: insights on the relation between mesiotemporal connectivity and cortical atrophy, Neuroimage, 42, 515, 10.1016/j.neuroimage.2008.04.261 Betting, 2006, Voxel-based morphometry in patients with idiopathic generalized epilepsies, Neuroimage, 32, 498, 10.1016/j.neuroimage.2006.04.174 Betting, 2006, MRI volumetry shows increased anterior thalamic volumes in patients with absence seizures, Epilepsy Behav, 8, 575, 10.1016/j.yebeh.2006.02.002 Binder, 2008, Use of preoperative functional MRI to predict verbal memory decline after temporal lobe epilepsy surgery, Epilepsia, 49, 1377, 10.1111/j.1528-1167.2008.01625.x Blumenfeld, 2004, Positive and negative network correlations in temporal lobe epilepsy, Cereb Cortex, 14, 892, 10.1093/cercor/bhh048 Bonilha, 2009, Automated MRI analysis for identification of hippocampal atrophy in temporal lobe epilepsy, Epilepsia, 50, 228, 10.1111/j.1528-1167.2008.01768.x Bonilha, 2003, Medial temporal lobe atrophy in patients with refractory temporal lobe epilepsy, J Neurol Neurosurg Psychiatry, 74, 1627, 10.1136/jnnp.74.12.1627 Bonilha, 2006, Gray matter atrophy associated with duration of temporal lobe epilepsy, Neuroimage, 32, 1070, 10.1016/j.neuroimage.2006.05.038 Bonilha, 2005, Voxel-based morphometry of the thalamus in patients with refractory medial temporal lobe epilepsy, Neuroimage, 25, 1016, 10.1016/j.neuroimage.2004.11.050 Bonilha, 2007, Asymmetrical extra-hippocampal grey matter loss related to hippocampal atrophy in patients with medial temporal lobe epilepsy, J Neurol Neurosurg Psychiatry, 78, 286, 10.1136/jnnp.2006.103994 Bookstein, 2001, “Voxel-based morphometry” should not be used with imperfectly registered images, Neuroimage, 14, 1454, 10.1006/nimg.2001.0770 Borsook, 2008, A ‘BOLD’ experiment in defining the utility of fMRI in drug development, Neuroimage, 42, 461, 10.1016/j.neuroimage.2008.04.268 Bosnell, 2008, Reproducibility of fMRI in the clinical setting: Implications for trial designs, Neuroimage, 42, 603, 10.1016/j.neuroimage.2008.05.005 Bouilleret, 2008, Basal ganglia involvement in temporal lobe epilepsy: a functional and morphologic study, Neurology, 70, 177, 10.1212/01.wnl.0000297514.47695.48 Bouilleret, 2002, Correlation between PET and SISCOM in temporal lobe epilepsy, J Nucl Med, 43, 991 Bouvard, 2005, Seizure-related short-term plasticity of benzodiazepine receptors in partial epilepsy: a [11C]flumazenil-PET study, Brain, 128, 1330, 10.1093/brain/awh470 Brazdil, 2005, Reorganization of language-related neuronal networks in patients with left temporal lobe epilepsy – an fMRI study, Eur J Neurol, 12, 268, 10.1111/j.1468-1331.2004.01127.x Bruggemann, 2007, Voxel-based morphometry in the detection of dysplasia and neoplasia in childhood epilepsy: combined grey/white matter analysis augments detection, Epilepsy Res, 77, 93, 10.1016/j.eplepsyres.2007.09.004 Bruggemann, 2009, Voxel-based morphometry in the detection of dysplasia and neoplasia in childhood epilepsy: limitations of grey matter analysis, J Clin Neurosci, 16, 780, 10.1016/j.jocn.2008.08.025 Carne, 2007, “Magnetic resonance imaging negative positron emission tomography positive” temporal lobe epilepsy: FDG-PET pattern differs from mesial temporal lobe epilepsy, Mol Imaging Biol, 9, 32, 10.1007/s11307-006-0073-0 Carne, 2007, ‘MRI-negative PET-positive’ temporal lobe epilepsy (TLE) and mesial TLE differ with quantitative MRI and PET: a case control study, BMC Neurol, 7, 16, 10.1186/1471-2377-7-16 Chan, 2006, Thalamic atrophy in childhood absence epilepsy, Epilepsia, 47, 399, 10.1111/j.1528-1167.2006.00435.x Chassagnon, 2009, SPM analysis of ictal-interictal SPECT in mesial temporal lobe epilepsy: relationships between ictal semiology and perfusion changes, Epilepsy Res, 85, 252, 10.1016/j.eplepsyres.2009.03.020 Chassoux, 2004, Metabolic changes and electro-clinical patterns in mesio-temporal lobe epilepsy: a correlative study, Brain, 127, 164, 10.1093/brain/awh014 Chlebus, 2007, FMRI evaluation of hemispheric language dominance using various methods of laterality index calculation, Exp Brain Res, 179, 365, 10.1007/s00221-006-0794-y Chugani, 1998, Imaging epileptogenic tubers in children with tuberous sclerosis complex using alpha-[11C]methyl-l-tryptophan positron emission tomography, Ann Neurol, 44, 858, 10.1002/ana.410440603 Chugani, 2008, Increased striatal serotonin synthesis following cortical resection in children with intractable epilepsy, Epilepsy Res, 78, 124, 10.1016/j.eplepsyres.2007.10.012 Chung, 2001, A unified statistical approach to deformation-based morphometry, Neuroimage, 14, 595, 10.1006/nimg.2001.0862 Chupin, 2007, Fully automatic segmentation of the hippocampus and the amygdala from MRI using hybrid prior knowledge, Med Image Comput Comput Assist Interv Int Conf Med Image Comput Comput Assist Interv, 10, 875 Chupin, 2009, Automatic segmentation of the hippocampus and the amygdala driven by hybrid constraints: method and validation, Neuroimage, 46, 749, 10.1016/j.neuroimage.2009.02.013 Ciumas, 2008, Imaging of odor perception delineates functional disintegration of the limbic circuits in mesial temporal lobe epilepsy, Neuroimage, 39, 578, 10.1016/j.neuroimage.2007.09.004 Cohen-Gadol, 2004, Mesial temporal lobe epilepsy: a proton magnetic resonance spectroscopy study and a histopathological analysis, J Neurosurg, 101, 613, 10.3171/jns.2004.101.4.0613 Colliot, 2006, Individual voxel-based analysis of gray matter in focal cortical dysplasia, Neuroimage, 29, 162, 10.1016/j.neuroimage.2005.07.021 Concha, 2005, Bilateral limbic diffusion abnormalities in unilateral temporal lobe epilepsy, Ann Neurol, 57, 188, 10.1002/ana.20334 Concha, 2007, Bilateral white matter diffusion changes persist after epilepsy surgery, Epilepsia, 48, 931, 10.1111/j.1528-1167.2007.01006.x Cormack, 2005, Extra-hippocampal grey matter density abnormalities in paediatric mesial temporal sclerosis, Neuroimage, 27, 635, 10.1016/j.neuroimage.2005.05.023 Dale, 1999, Cortical surface-based analysis. I. Segmentation and surface reconstruction, Neuroimage, 9, 179, 10.1006/nimg.1998.0395 De Martino, 2008, Combining multivariate voxel selection and support vector machines for mapping and classification of fMRI spatial patterns, Neuroimage, 43, 44, 10.1016/j.neuroimage.2008.06.037 De Tiège, 2008, Metabolic evidence for remote inhibition in epilepsies with continuous spike-waves during sleep, Neuroimage, 40, 802, 10.1016/j.neuroimage.2007.11.043 Detre, 1998, Functional MRI lateralization of memory in temporal lobe epilepsy, Neurology, 50, 926, 10.1212/WNL.50.4.926 Diehl, 2001, Postictal diffusion-weighted imaging for the localization of focal epileptic areas in temporal lobe epilepsy, Epilepsia, 42, 21, 10.1046/j.1528-1157.2001.19500.x Diehl, 2005, Postictal diffusion tensor imaging, Epilepsy Res, 65, 137, 10.1016/j.eplepsyres.2005.05.007 Donaire, 2009, Identifying the structures involved in seizure generation using sequential analysis of ictal-fMRI data, Neuroimage, 47, 173, 10.1016/j.neuroimage.2009.03.059 Donaire, 2009, Sequential analysis of fMRI images: a new approach to study human epileptic networks, Epilepsia, 50, 2526, 10.1111/j.1528-1167.2009.02152.x Dupont, 2009, Dynamic perfusion patterns in temporal lobe epilepsy, Eur J Nucl Med Mol Imaging, 36, 823, 10.1007/s00259-008-1040-6 Duzel, 2006, Hippocampal atrophy in temporal lobe epilepsy is correlated with limbic systems atrophy, J Neurol, 253, 294, 10.1007/s00415-005-0981-y Erbayat Altay, 2005, Correlation of severity of FDG-PET hypometabolism and interictal regional delta slowing in temporal lobe epilepsy, Epilepsia, 46, 573, 10.1111/j.0013-9580.2005.08204.x Eriksson, 2007, Correlation of quantitative MRI and neuropathology in epilepsy surgical resection specimens–T2 correlates with neuronal tissue in gray matter, Neuroimage, 37, 48, 10.1016/j.neuroimage.2007.04.051 Eriksson, 2009, Quantitative grey matter histological measures do not correlate with grey matter probability values from in vivo MRI in the temporal lobe, J Neurosci Methods, 181, 111, 10.1016/j.jneumeth.2009.05.001 Eriksson, 2008, PROPELLER MRI visualizes detailed pathology of hippocampal sclerosis, Epilepsia, 49, 33, 10.1111/j.1528-1167.2007.01277.x Eriksson, 2009, Cortical neuronal loss and hippocampal sclerosis are not detected by voxel-based morphometry in individual epilepsy surgery patients, Hum Brain Mapp, 10.1002/hbm.20757 Federico, 2005, Functional MRI of the pre-ictal state, Brain, 128, 1811, 10.1093/brain/awh533 Fedi, 2008, Reduced striatal D1 receptor binding in autosomal dominant nocturnal frontal lobe epilepsy, Neurology, 71, 795, 10.1212/01.wnl.0000316192.52731.77 Fedi, 2001, Localizing value of alpha-methyl-l-tryptophan PET in intractable epilepsy of neocortical origin, Neurology, 57, 1629, 10.1212/WNL.57.9.1629 Fischl, 2002, Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain, Neuron, 33, 341, 10.1016/S0896-6273(02)00569-X Fischl, 1999, Cortical surface-based analysis. II. Inflation, flattening, and a surface-based coordinate system, Neuroimage, 9, 195, 10.1006/nimg.1998.0396 Fischl, 1999, High-resolution intersubject averaging and a coordinate system for the cortical surface, Hum Brain Mapp, 8, 272, 10.1002/(SICI)1097-0193(1999)8:4<272::AID-HBM10>3.0.CO;2-4 Focke, 2009, Automated normalized FLAIR imaging in MRI-negative patients with refractory focal epilepsy, Epilepsia, 50, 1484, 10.1111/j.1528-1167.2009.02022.x Focke, 2008, Voxel-based analysis of whole brain FLAIR at 3T detects focal cortical dysplasia, Epilepsia, 49, 786, 10.1111/j.1528-1167.2007.01474.x Focke, 2008, Voxel-based diffusion tensor imaging in patients with mesial temporal lobe epilepsy and hippocampal sclerosis, Neuroimage, 40, 728, 10.1016/j.neuroimage.2007.12.031 Fojtikova, 2006, Magnetic resonance spectroscopy of the thalamus in patients with typical absence epilepsy, Seizure, 15, 533, 10.1016/j.seizure.2006.06.007 Fojtikova, 2007, Magnetic resonance spectroscopy of the thalamus in patients with mesial temporal lobe epilepsy and hippocampal sclerosis, Epileptic Disord, 9, S59 Frings, 2008, Lateralization of hippocampal activation differs between left and right temporal lobe epilepsy patients and correlates with postsurgical verbal learning decrement, Epilepsy Res, 78, 161, 10.1016/j.eplepsyres.2007.11.006 Fukuda, 2006, Ictal SPECT analyzed by three-dimensional stereotactic surface projection in frontal lobe epilepsy patients, Epilepsy Res, 68, 95, 10.1016/j.eplepsyres.2005.09.032 Gaillard, 2002, Language dominance in partial epilepsy patients identified with an fMRI reading task, Neurology, 59, 256, 10.1212/WNL.59.2.256 Gaillard, 2004, FMRI language task panel improves determination of language dominance, Neurology, 63, 1403, 10.1212/01.WNL.0000141852.65175.A7 Gaillard, 2007, Atypical language in lesional and nonlesional complex partial epilepsy, Neurology, 69, 1761, 10.1212/01.wnl.0000289650.48830.1a Giovacchini, 2005, 5-HT 1A receptors are reduced in temporal lobe epilepsy after partial-volume correction, J Nucl Med, 46, 1128 Goncalves Pereira, 2005, MR volumetric analysis of the piriform cortex and cortical amygdala in drug-refractory temporal lobe epilepsy, AJNR Am J Neuroradiol, 26, 319 Goncalves Pereira, 2006, Apparent diffusion coefficient mapping of the hippocampus and the amygdala in pharmaco-resistant temporal lobe epilepsy, AJNR Am J Neuroradiol, 27, 671 Gong, 2008, Thalamic diffusion and volumetry in temporal lobe epilepsy with and without mesial temporal sclerosis, Epilepsy Res, 80, 184, 10.1016/j.eplepsyres.2008.04.002 Gotman, 2008, Epileptic networks studied with EEG-fMRI, Epilepsia, 49, 42, 10.1111/j.1528-1167.2008.01509.x Gotman, 2005, Generalized epileptic discharges show thalamocortical activation and suspension of the default state of the brain, Proc Natl Acad Sci USA, 102, 15236, 10.1073/pnas.0504935102 Grova, 2008, Concordance between distributed EEG source localization and simultaneous EEG-fMRI studies of epileptic spikes, Neuroimage, 39, 755, 10.1016/j.neuroimage.2007.08.020 Guimaraes, 2007, Distribution of regional gray matter abnormalities in a pediatric population with temporal lobe epilepsy and correlation with neuropsychological performance, Epilepsy Behav, 11, 558, 10.1016/j.yebeh.2007.07.005 Guye, 2007, What is the significance of interictal water diffusion changes in frontal lobe epilepsies?, Neuroimage, 35, 28, 10.1016/j.neuroimage.2006.11.049 Guye, 2005, 1H-MRS imaging in intractable frontal lobe epilepsies characterized by depth electrode recording, Neuroimage, 26, 1174, 10.1016/j.neuroimage.2005.03.023 Hajek, 2009, 1H MR spectroscopy in histopathological subgroups of mesial temporal lobe epilepsy, Eur Radiol, 19, 400, 10.1007/s00330-008-1156-x Haki, 2007, Proton magnetic resonance spectroscopy study of bilateral thalamus in juvenile myoclonic epilepsy, Seizure, 16, 287, 10.1016/j.seizure.2007.02.017 Hallez, 2008, Dipole estimation errors due to differences in modeling anisotropic conductivities in realistic head models for EEG source analysis, Phys Med Biol, 53, 1877, 10.1088/0031-9155/53/7/005 Hallez, 2005, A finite difference method with reciprocity used to incorporate anisotropy in electroencephalogram dipole source localization, Phys Med Biol, 50, 3787, 10.1088/0031-9155/50/16/009 Hamandi, 2008, BOLD and perfusion changes during epileptic generalised spike wave activity, Neuroimage, 39, 608, 10.1016/j.neuroimage.2007.07.009 Hamandi, 2008, Combined EEG-fMRI and tractography to visualise propagation of epileptic activity, J Neurol Neurosurg Psychiatry, 79, 594, 10.1136/jnnp.2007.125401 Hamandi, 2006, EEG-fMRI of idiopathic and secondarily generalized epilepsies, Neuroimage, 31, 1700, 10.1016/j.neuroimage.2006.02.016 Hammen, 2006, Identifying the affected hemisphere by (1)H-MR spectroscopy in patients with temporal lobe epilepsy and no pathological findings in high resolution MRI, Eur J Neurol, 13, 482, 10.1111/j.1468-1331.2006.01293.x Hammen, 2007, 1H-MR spectroscopy indicates severity markers in temporal lobe epilepsy: correlations between metabolic alterations, seizures, and epileptic discharges in EEG, Epilepsia, 48, 263, 10.1111/j.1528-1167.2006.00856.x Hammers, 2007, Automatic detection and quantification of hippocampal atrophy on MRI in temporal lobe epilepsy: a proof-of-principle study, Neuroimage, 36, 38, 10.1016/j.neuroimage.2007.02.031 Hammers, 2005, Periventricular white matter flumazenil binding and postoperative outcome in hippocampal sclerosis, Epilepsia, 46, 944, 10.1111/j.1528-1167.2005.30904.x Hammers, 2002, Abnormalities of grey and white matter [11C]flumazenil binding in temporal lobe epilepsy with normal MRI, Brain, 125, 2257, 10.1093/brain/awf233 Hammers, 2001, Neocortical abnormalities of [11C]-flumazenil PET in mesial temporal lobe epilepsy, Neurology, 56, 897, 10.1212/WNL.56.7.897 Hawco, 2007, BOLD changes occur prior to epileptic spikes seen on scalp EEG, Neuroimage, 35, 1450, 10.1016/j.neuroimage.2006.12.042 Helms, 2006, Increased thalamus levels of glutamate and glutamine (Glx) in patients with idiopathic generalised epilepsy, J Neurol Neurosurg Psychiatry, 77, 489, 10.1136/jnnp.2005.074682 Helmstaedter, 2006, Shift-back of right into left hemisphere language dominance after control of epileptic seizures: evidence for epilepsy driven functional cerebral organization, Epilepsy Res, 70, 257, 10.1016/j.eplepsyres.2006.03.005 Henry, 2004, The role of positron emission tomography with [18F]fluorodeoxyglucose in the evaluation of the epilepsies, Neuroimag Clin N Am, 14, 517, 10.1016/j.nic.2004.04.011 Hermann, 2005, Cerebellar atrophy in temporal lobe epilepsy, Epilepsy Behav, 7, 279, 10.1016/j.yebeh.2005.05.022 Hetherington, 2007, A subcortical network of dysfunction in TLE measured by magnetic resonance spectroscopy, Neurology, 69, 2256, 10.1212/01.wnl.0000286945.21270.6d Hogan, 2008, Hippocampal deformation mapping in MRI negative PET positive temporal lobe epilepsy, J Neurol Neurosurg Psychiatry, 79, 636, 10.1136/jnnp.2007.123406 Hogan, 2006, Composite SISCOM perfusion patterns in right and left temporal seizures, Arch Neurol, 63, 1419, 10.1001/archneur.63.10.1419 Hogan, 2006, Predictive value of hippocampal MR imaging-based high-dimensional mapping in mesial temporal epilepsy: preliminary findings, AJNR Am J Neuroradiol, 27, 2149 Hua, 2008, 3D characterization of brain atrophy in Alzheimer’s disease and mild cognitive impairment using tensor-based morphometry, Neuroimage, 41, 19, 10.1016/j.neuroimage.2008.02.010 Huberfeld, 2006, Ictal brain hyperperfusion contralateral to seizure onset: the SPECT mirror image, Epilepsia, 47, 123, 10.1111/j.1528-1167.2006.00378.x Hufnagel, 2003, Brain diffusion after single seizures, Epilepsia, 44, 54, 10.1046/j.1528-1157.2003.07802.x Hugg, 1996, Normalization of contralateral metabolic function following temporal lobectomy demonstrated by 1H magnetic resonance spectroscopic imaging, Ann Neurol, 40, 236, 10.1002/ana.410400215 Huppertz, 2005, Enhanced visualization of blurred gray-white matter junctions in focal cortical dysplasia by voxel-based 3D MRI analysis, Epilepsy Res, 67, 35, 10.1016/j.eplepsyres.2005.07.009 Hutton, 2008, Voxel-based cortical thickness measurements in MRI, Neuroimage, 40, 1701, 10.1016/j.neuroimage.2008.01.027 Ito, 2007, Changes in central 5-HT(1A) receptor binding in mesial temporal epilepsy measured by positron emission tomography with [(11)C]WAY100635, Epilepsy Res, 73, 111, 10.1016/j.eplepsyres.2006.09.003 Jackson, 1999, Hippocampal sclerosis: development in adult life, Dev Neurosci, 21, 207, 10.1159/000017400 Jacobs, 2007, Hemodynamic responses to interictal epileptiform discharges in children with symptomatic epilepsy, Epilepsia, 48, 2068, 10.1111/j.1528-1167.2007.01192.x Jacobs, 2008, Evaluation of epileptogenic networks in children with tuberous sclerosis complex using EEG-fMRI, Epilepsia, 49, 816, 10.1111/j.1528-1167.2007.01486.x Jann, 2008, BOLD correlates of continuously fluctuating epileptic activity isolated by independent component analysis, Neuroimage, 42, 635, 10.1016/j.neuroimage.2008.05.001 Janszky, 2003, Functional organization of the brain with malformations of cortical development, Ann Neurol, 53, 759, 10.1002/ana.10545 Janszky, 2005, Functional MRI predicts memory performance after right mesiotemporal epilepsy surgery, Epilepsia, 46, 244, 10.1111/j.0013-9580.2005.10804.x Janszky, 2006, Left-sided interictal epileptic activity induces shift of language lateralization in temporal lobe epilepsy: an fMRI study, Epilepsia, 47, 921, 10.1111/j.1528-1167.2006.00514.x Joo, 2005, Postoperative alteration of cerebral glucose metabolism in mesial temporal lobe epilepsy, Brain, 128, 1802, 10.1093/brain/awh534 Juhasz, 2009, Focal decreases of cortical GABAA receptor binding remote from the primary seizure focus: what do they indicate?, Epilepsia, 50, 240, 10.1111/j.1528-1167.2008.01721.x Kagawa, 2005, Epilepsy surgery outcome in children with tuberous sclerosis complex evaluated with alpha-[11C]methyl-l-tryptophan positron emission tomography (PET), J Child Neurol, 20, 429, 10.1177/08830738050200050701 Kaiboriboon, 2005, Quantitative analysis of cerebral blood flow patterns in mesial temporal lobe epilepsy using composite SISCOM, J Nucl Med, 46, 38 Katramados, 2009, Periictal diffusion abnormalities of the thalamus in partial status epilepticus, Epilepsia, 50, 265, 10.1111/j.1528-1167.2008.01736.x Keller, 2009, Quantitative MRI of the prefrontal cortex and executive function in patients with temporal lobe epilepsy, Epilepsy Behav, 15, 186, 10.1016/j.yebeh.2009.03.005 Keller, 2007, Persistent seizures following left temporal lobe surgery are associated with posterior and bilateral structural and functional brain abnormalities, Epilepsy Res, 74, 131, 10.1016/j.eplepsyres.2007.02.005 Keller, 2008, Voxel-based morphometry of temporal lobe epilepsy: an introduction and review of the literature, Epilepsia, 49, 741, 10.1111/j.1528-1167.2007.01485.x Kho, 2007, Working memory deficits after resection of the dorsolateral prefrontal cortex predicted by functional magnetic resonance imaging and electrocortical stimulation mapping. Case report, J Neurosurg, 106, 501 Kim, 2009, Predictors of surgical outcome and pathologic considerations in focal cortical dysplasia, Neurology, 72, 211, 10.1212/01.wnl.0000327825.48731.c3 Kim, 2001, Transient MR signal changes in patients with generalized tonicoclonic seizure or status epilepticus: periictal diffusion-weighted imaging, AJNR Am J Neuroradiol, 22, 1149 Kim, 2007, Regional grey matter abnormalities in juvenile myoclonic epilepsy: a voxel-based morphometry study, Neuroimage, 37, 1132, 10.1016/j.neuroimage.2007.06.025 Kimiwada, 2006, Hippocampal and thalamic diffusion abnormalities in children with temporal lobe epilepsy, Epilepsia, 47, 167, 10.1111/j.1528-1167.2006.00383.x Knowlton, 2008, Functional imaging. II. Prediction of epilepsy surgery outcome, Ann Neurol, 64, 35, 10.1002/ana.21419 Knowlton, 2008, Functional imaging. I. Relative predictive value of intracranial electroencephalography, Ann Neurol, 64, 25, 10.1002/ana.21389 Kobayashi, 2006, Negative BOLD responses to epileptic spikes, Hum Brain Mapp, 27, 488, 10.1002/hbm.20193 Korja, 2007, Substantial thalamostriatal dopaminergic defect in Unverricht–Lundborg disease, Epilepsia, 48, 1768, 10.1111/j.1528-1167.2007.01118.x Kosior, 2009, Single-subject voxel-based relaxometry for clinical assessment of temporal lobe epilepsy, Epilepsy Res, 86, 23, 10.1016/j.eplepsyres.2009.04.001 Koylu, 2006, Neural correlates of verbal semantic memory in patients with temporal lobe epilepsy, Epilepsy Res, 72, 178, 10.1016/j.eplepsyres.2006.08.002 Kuzniecky, 1998, Relative utility of 1H spectroscopic imaging and hippocampal volumetry in the lateralization of mesial temporal lobe epilepsy, Neurology, 51, 66, 10.1212/WNL.51.1.66 Kuzniecky, 2001, Magnetic resonance spectroscopic imaging in temporal lobe epilepsy: neuronal dysfunction or cell loss?, Arch Neurol, 58, 2048, 10.1001/archneur.58.12.2048 la Fougere, 2009, PET and SPECT in epilepsy: a critical review, Epilepsy Behav, 15, 50, 10.1016/j.yebeh.2009.02.025 Lantz, 2006, Extent of preoperative abnormalities and focus lateralization predict postoperative normalization of contralateral 1H-magnetic resonance spectroscopy metabolite levels in patients with temporal lobe epilepsy, AJNR Am J Neuroradiol, 27, 1766 Laufs, 2008, Recent advances in recording electrophysiological data simultaneously with magnetic resonance imaging, Neuroimage, 40, 515, 10.1016/j.neuroimage.2007.11.039 Laufs, 2007, Electroencephalography/functional MRI in human epilepsy: what it currently can and cannot do, Curr Opin Neurol, 20, 417, 10.1097/WCO.0b013e3282202b92 Laufs, 2007, Temporal lobe interictal epileptic discharges affect cerebral activity in “default mode” brain regions, Hum Brain Mapp, 28, 1023, 10.1002/hbm.20323 Lee, 2009, Relationship between hypometabolic patterns and ictal scalp EEG patterns in patients with unilateral hippocampal sclerosis: an FDG-PET study, Epilepsy Res, 84, 187, 10.1016/j.eplepsyres.2009.02.005 Lee, 2005, Effect of seizure on hippocampus in mesial temporal lobe epilepsy and neocortical epilepsy: an MRS study, Neuroradiology, 47, 916, 10.1007/s00234-005-1447-8 Lee, 2006, Ictal SPECT in neocortical epilepsies: clinical usefulness and factors affecting the pattern of hyperperfusion, Neuroradiology, 48, 678, 10.1007/s00234-006-0106-z Leite, 2007, Multivoxel proton MR spectroscopy in malformations of cortical development, AJNR Am J Neuroradiol, 28, 1071, 10.3174/ajnr.A0511 Liew, 2009, 18F-FCWAY and 18F-FDG PET in MRI-negative temporal lobe epilepsy, Epilepsia, 50, 234, 10.1111/j.1528-1167.2008.01789.x Lillywhite, 2009, Neuropsychological and functional MRI studies provide converging evidence of anterior language dysfunction in BECTS, Epilepsia, 50, 2276, 10.1111/j.1528-1167.2009.02065.x Lin, 2007, Reduced neocortical thickness and complexity mapped in mesial temporal lobe epilepsy with hippocampal sclerosis, Cereb Cortex, 17, 2007, 10.1093/cercor/bhl109 Liston, 2006, Analysis of EEG-fMRI data in focal epilepsy based on automated spike classification and Signal Space Projection, Neuroimage, 31, 1015, 10.1016/j.neuroimage.2006.01.040 Liu, 2005, Cerebral damage in epilepsy: a population-based longitudinal quantitative MRI study, Epilepsia, 46, 1482, 10.1111/j.1528-1167.2005.51603.x Maccotta, 2007, Changing frontal contributions to memory before and after medial temporal lobectomy, Cereb Cortex, 17, 443, 10.1093/cercor/bhj161 Matsuda, 2009, Contribution of subtraction ictal SPECT coregistered to MRI to epilepsy surgery: a multicenter study, Ann Nucl Med, 23, 283, 10.1007/s12149-009-0236-6 Meade, 2008, Rhinal cortex asymmetries in patients with mesial temporal sclerosis, Seizure, 17, 234, 10.1016/j.seizure.2007.07.010 Medina, 2007, Role of functional MR in determining language dominance in epilepsy and nonepilepsy populations: a Bayesian analysis, Radiology, 242, 94, 10.1148/radiol.2421050677 Meeren, 2002, Cortical focus drives widespread corticothalamic networks during spontaneous absence seizures in rats, J Neurosci, 22, 1480, 10.1523/JNEUROSCI.22-04-01480.2002 Merlet, 2004, 5-HT1A receptor binding and intracerebral activity in temporal lobe epilepsy: an [18F]MPPF-PET study, Brain, 127, 900, 10.1093/brain/awh109 Merschhemke, 2003, Quantitative MRI detects abnormalities in relatives of patients with epilepsy and malformations of cortical development, Neuroimage, 18, 642, 10.1016/S1053-8119(02)00052-6 Messori, 2005, Predicting posttraumatic epilepsy with MRI: prospective longitudinal morphologic study in adults, Epilepsia, 46, 1472, 10.1111/j.1528-1167.2005.34004.x Milligan, 2009, Frequency and patterns of MRI abnormalities due to status epilepticus, Seizure, 18, 104, 10.1016/j.seizure.2008.07.004 Moeller, 2008, Changes in activity of striato-thalamo-cortical network precede generalized spike wave discharges, Neuroimage, 39, 1839, 10.1016/j.neuroimage.2007.10.058 Morgan, 2007, Cluster analysis detection of functional MRI activity in temporal lobe epilepsy, Epilepsy Res, 76, 22, 10.1016/j.eplepsyres.2007.06.008 Morgan, 2004, Resting functional MRI with temporal clustering analysis for localization of epileptic activity without EEG, Neuroimage, 21, 473, 10.1016/j.neuroimage.2003.08.031 Morra, 2008, Validation of a fully automated 3D hippocampal segmentation method using subjects with Alzheimer’s disease mild cognitive impairment, and elderly controls, Neuroimage, 43, 59, 10.1016/j.neuroimage.2008.07.003 Mory, 2003, Thalamic dysfunction in juvenile myoclonic epilepsy: a proton MRS study, Epilepsia, 44, 1402, 10.1046/j.1528-1157.2003.67702.x Mueller, 2009, Shrinkage of the hippocampal remnant after surgery for temporal lobe epilepsy: impact on seizure and neuropsychological outcomes, Epilepsy Behav, 14, 379, 10.1016/j.yebeh.2008.12.003 Mueller, 2009, Subfield atrophy pattern in temporal lobe epilepsy with and without mesial sclerosis detected by high-resolution MRI at 4Tesla: preliminary results, Epilepsia, 50, 1474, 10.1111/j.1528-1167.2009.02010.x Mueller, 2005, Metabolic characteristics of cortical malformations causing epilepsy, J Neurol, 252, 1082, 10.1007/s00415-005-0819-7 Mueller, 2006, Voxel-based optimized morphometry (VBM) of gray and white matter in temporal lobe epilepsy (TLE) with and without mesial temporal sclerosis, Epilepsia, 47, 900, 10.1111/j.1528-1167.2006.00512.x Natsume, 2003, MRI volumetry of the thalamus in temporal, extratemporal, and idiopathic generalized epilepsy, Neurology, 60, 1296, 10.1212/01.WNL.0000058764.34968.C2 Nelissen, 2006, Correlations of interictal FDG-PET metabolism and ictal SPECT perfusion changes in human temporal lobe epilepsy with hippocampal sclerosis, Neuroimage, 32, 684, 10.1016/j.neuroimage.2006.04.185 Newton, 1992, Dystonia, clinical lateralization, and regional blood flow changes in temporal lobe seizures, Neurology, 42, 371, 10.1212/WNL.42.2.371 Nishida, 2008, Cortical glucose metabolism positively correlates with gamma-oscillations in nonlesional focal epilepsy, Neuroimage, 42, 1275, 10.1016/j.neuroimage.2008.06.027 Noulhiane, 2006, A volumetric MRI study of the hippocampus and the parahippocampal region after unilateral medial temporal lobe resection, J Neurosci Methods, 156, 293, 10.1016/j.jneumeth.2006.02.021 O’Brien, 2008, The cost-effective use of 18F-FDG PET in the presurgical evaluation of medically refractory focal epilepsy, J Nucl Med, 49, 931, 10.2967/jnumed.107.048207 O’Brien, 1998, Subtraction ictal SPET co-registered to MRI in partial epilepsy: description and technical validation of the method with phantom and patient studies, Nucl Med Commun, 19, 31, 10.1097/00006231-199801000-00006 O’Brien, 2004, Subtraction SPECT coregistered to MRI in focal malformations of cortical development: localization of the epileptogenic zone in epilepsy surgery candidates, Epilepsia, 45, 367, 10.1111/j.0013-9580.2004.54703.x O’Brien, 2000, Subtraction peri-ictal SPECT is predictive of extratemporal epilepsy surgery outcome, Neurology, 55, 1668, 10.1212/WNL.55.11.1668 O’Brien, 1999, Subtraction SPECT co-registered to MRI improves postictal SPECT localization of seizure foci, Neurology, 52, 137, 10.1212/WNL.52.1.137 Oh, 2004, Role of immediate postictal diffusion-weighted MRI in localizing epileptogenic foci of mesial temporal lobe epilepsy and non-lesional neocortical epilepsy, Seizure, 13, 509, 10.1016/j.seizure.2003.12.005 Pardoe, 2008, Multi-site voxel-based morphometry: methods and a feasibility demonstration with childhood absence epilepsy, Neuroimage, 42, 611, 10.1016/j.neuroimage.2008.05.007 Pell, 2008, Selection of the control group for VBM analysis: influence of covariates, matching and sample size, Neuroimage, 41, 1324, 10.1016/j.neuroimage.2008.02.050 Pell, 2008, Composite voxel-based analysis of volume and T2 relaxometry in temporal lobe epilepsy, Neuroimage, 39, 1151, 10.1016/j.neuroimage.2007.09.061 Poduri, 2007, Focal cortical malformations can show asymmetrically higher uptake on interictal fluorine-18 fluorodeoxyglucose positron emission tomography (PET), J Child Neurol, 22, 232, 10.1177/0883073807300305 Powell, 2008, Imaging language pathways predicts postoperative naming deficits, J Neurol Neurosurg Psychiatry, 79, 327, 10.1136/jnnp.2007.126078 Powell, 2005, MR tractography predicts visual field defects following temporal lobe resection, Neurology, 65, 596, 10.1212/01.wnl.0000172858.20354.73 Powell, 2007, Abnormalities of language networks in temporal lobe epilepsy, Neuroimage, 36, 209, 10.1016/j.neuroimage.2007.02.028 Powell, 2007, Reorganization of verbal and nonverbal memory in temporal lobe epilepsy due to unilateral hippocampal sclerosis, Epilepsia, 48, 1512, 10.1111/j.1528-1167.2007.01053.x Powell, 2008, Preoperative fMRI predicts memory decline following anterior temporal lobe resection, J Neurol Neurosurg Psychiatry, 79, 686, 10.1136/jnnp.2007.115139 Provenzale, 2008, Hippocampal MRI signal hyperintensity after febrile status epilepticus is predictive of subsequent mesial temporal sclerosis, AJR Am J Roentgenol, 190, 976, 10.2214/AJR.07.2407 Pulsipher, 2009, Thalamofrontal circuitry and executive dysfunction in recent-onset juvenile myoclonic epilepsy, Epilepsia, 50, 1210, 10.1111/j.1528-1167.2008.01952.x Pulsipher, 2007, MRI volume loss of subcortical structures in unilateral temporal lobe epilepsy, Epilepsy Behav, 11, 442, 10.1016/j.yebeh.2007.08.007 Rabin, 2004, Functional MRI predicts post-surgical memory following temporal lobectomy, Brain, 127, 2286, 10.1093/brain/awh281 Restom, 2008, Calibrated fMRI in the medial temporal lobe during a memory-encoding task, Neuroimage, 40, 1495, 10.1016/j.neuroimage.2008.01.038 Richardson, 2006, BOLD correlates of EMG spectral density in cortical myoclonus: description of method and case report, Neuroimage, 32, 558, 10.1016/j.neuroimage.2006.04.183 Richardson, 2004, Emotional memory encoding depends on amygdala and hippocampus and their interactions, Nat Neurosci, 7, 278, 10.1038/nn1190 Richardson, 2003, Preserved verbal memory function in left medial temporal pathology involves reorganisation of function to right medial temporal lobe, Neuroimage, 20, S112, 10.1016/j.neuroimage.2003.09.008 Richardson, 2006, Memory fMRI in left hippocampal sclerosis: optimizing the approach to predicting postsurgical memory, Neurology, 66, 699, 10.1212/01.wnl.0000201186.07716.98 Richardson, 2004, Pre-operative verbal memory fMRI predicts post-operative memory decline after left temporal lobe resection, Brain, 127, 2419, 10.1093/brain/awh293 Riederer, 2006, 1H magnetic resonance spectroscopy at 3T in cryptogenic and mesial temporal lobe epilepsy, NMR Biomed, 19, 544, 10.1002/nbm.1029 Riederer, 2008, Network atrophy in temporal lobe epilepsy: a voxel-based morphometry study, Neurology, 71, 419, 10.1212/01.wnl.0000324264.96100.e0 Ritter, 2008, High-frequency (600Hz) population spikes in human EEG delineate thalamic and cortical fMRI activation sites, Neuroimage, 42, 483, 10.1016/j.neuroimage.2008.05.026 Roebling, 2009, Evaluation of cognition, structural, and functional MRI in juvenile myoclonic epilepsy, Epilepsia, 50, 2456, 10.1111/j.1528-1167.2009.02127.x Rosenberger, 2009, Interhemispheric and intrahemispheric language reorganization in complex partial epilepsy, Neurology, 72, 1830, 10.1212/WNL.0b013e3181a7114b Rugg-Gunn, 2005, Whole-brain T2 mapping demonstrates occult abnormalities in focal epilepsy, Neurology, 64, 318, 10.1212/01.WNL.0000149642.93493.F4 Rugg-Gunn, 2006, Imaging the neocortex in epilepsy with double inversion recovery imaging, Neuroimage, 31, 39, 10.1016/j.neuroimage.2005.11.034 Rullmann, 2009, EEG source analysis of epileptiform activity using a 1Âmm anisotropic hexahedra finite element head model, Neuroimage, 44, 399, 10.1016/j.neuroimage.2008.09.009 Rutten, 2002, FMRI-determined language lateralization in patients with unilateral or mixed language dominance according to the Wada test, Neuroimage, 17, 447, 10.1006/nimg.2002.1196 Sabsevitz, 2003, Use of preoperative functional neuroimaging to predict language deficits from epilepsy surgery, Neurology, 60, 1788, 10.1212/01.WNL.0000068022.05644.01 Salek-Haddadi, 2006, Hemodynamic correlates of epileptiform discharges: an EEG-fMRI study of 63 patients with focal epilepsy, Brain Res, 1088, 148, 10.1016/j.brainres.2006.02.098 Salek-Haddadi, 2003, Functional magnetic resonance imaging of human absence seizures, Ann Neurol, 53, 663, 10.1002/ana.10586 Salek-Haddadi, 2009, Imaging seizure activity: a combined EEG/EMG-fMRI study in reading epilepsy, Epilepsia, 50, 256, 10.1111/j.1528-1167.2008.01737.x Salmenpera, 2005, Hippocampal damage in newly diagnosed focal epilepsy: a prospective MRI study, Neurology, 64, 62, 10.1212/01.WNL.0000148643.36513.2A Salmenpera, 2006, High-resolution diffusion tensor imaging of the hippocampus in temporal lobe epilepsy, Epilepsy Res, 71, 102, 10.1016/j.eplepsyres.2006.05.020 Salmenpera, 2006, Postictal diffusion weighted imaging, Epilepsy Res, 70, 133, 10.1016/j.eplepsyres.2006.03.010 Salmenpera, 2007, Evaluation of quantitative magnetic resonance imaging contrasts in MRI-negative refractory focal epilepsy, Epilepsia, 48, 229, 10.1111/j.1528-1167.2007.00918.x Savic, 2000, MR spectroscopy shows reduced frontal lobe concentrations of N-acetyl aspartate in patients with juvenile myoclonic epilepsy, Epilepsia, 41, 290, 10.1111/j.1528-1157.2000.tb00158.x Savic, 2004, MRS shows syndrome differentiated metabolite changes in human-generalized epilepsies, Neuroimage, 21, 163, 10.1016/j.neuroimage.2003.08.034 Schacher, 2006, Amygdala fMRI lateralizes temporal lobe epilepsy, Neurology, 66, 81, 10.1212/01.wnl.0000191303.91188.00 Schoene-Bake, 2009, Widespread affections of large fiber tracts in postoperative temporal lobe epilepsy, Neuroimage, 46, 569, 10.1016/j.neuroimage.2009.03.013 Schramm, 2008, Temporal lobe epilepsy surgery and the quest for optimal extent of resection: a review, Epilepsia, 49, 1296 Scott, 2002, Magnetic resonance imaging findings within 5 days of status epilepticus in childhood, Brain, 125, 1951, 10.1093/brain/awf202 Seeck, 2005, Subcortical nuclei volumetry in idiopathic generalized epilepsy, Epilepsia, 46, 1642, 10.1111/j.1528-1167.2005.00259.x Seidenberg, 2008, Thalamic atrophy and cognition in unilateral temporal lobe epilepsy, J Int Neuropsychol Soc, 14, 384, 10.1017/S1355617708080399 Seidenberg, 2005, Ipsilateral and contralateral MRI volumetric abnormalities in chronic unilateral temporal lobe epilepsy and their clinical correlates, Epilepsia, 46, 420, 10.1111/j.0013-9580.2005.27004.x Serles, 2001, Time course of postoperative recovery of N-acetyl-aspartate in temporal lobe epilepsy, Epilepsia, 42, 190 Simister, 2003, A proton magnetic resonance spectroscopy study of metabolites in the occipital lobes in epilepsy, Epilepsia, 44, 550, 10.1046/j.1528-1157.2003.19102.x Simister, 2003, Proton MRS reveals frontal lobe metabolite abnormalities in idiopathic generalized epilepsy, Neurology, 61, 897, 10.1212/01.WNL.0000086903.69738.DC Simister, 2007, The effect of sodium valproate on proton MRS visible neurochemical concentrations, Epilepsy Res, 74, 215, 10.1016/j.eplepsyres.2007.03.001 Simister, 2007, Proton magnetic resonance spectroscopy of malformations of cortical development causing epilepsy, Epilepsy Res, 74, 107, 10.1016/j.eplepsyres.2007.02.002 Sokol, 2003, From swelling to sclerosis: acute change in mesial hippocampus after prolonged febrile seizure, Seizure, 12, 237, 10.1016/S1059-1311(02)00195-4 Spencer, 2002, Neural networks in human epilepsy: evidence of and implications for treatment, Epilepsia, 43, 219, 10.1046/j.1528-1157.2002.26901.x Stefanovic, 2005, Hemodynamic and metabolic responses to activation, deactivation and epileptic discharges, Neuroimage, 28, 205, 10.1016/j.neuroimage.2005.05.038 Stewart, 2009, Contributions of volumetrics of the hippocampus and thalamus to verbal memory in temporal lobe epilepsy patients, Brain Cogn, 69, 65, 10.1016/j.bandc.2008.05.005 Stokes, 2004 Sveller, 2006, Relationship between language lateralization and handedness in left-hemispheric partial epilepsy, Neurology, 67, 1813, 10.1212/01.wnl.0000244465.74707.42 Szabo, 2006, MR imaging volumetry of subcortical structures and cerebellar hemispheres in temporal lobe epilepsy, AJNR Am J Neuroradiol, 27, 2155 Szabo, 2005, Diffusion-weighted and perfusion MRI demonstrates parenchymal changes in complex partial status epilepticus, Brain, 128, 1369, 10.1093/brain/awh454 Szaflarski, 2008, Comprehensive presurgical functional MRI language evaluation in adult patients with epilepsy, Epilepsy Behav, 12, 74, 10.1016/j.yebeh.2007.07.015 Takaya, 2009, Improved cerebral function in mesial temporal lobe epilepsy after subtemporal amygdalohippocampectomy, Brain, 132, 185, 10.1093/brain/awn218 Taki, 2009, High gamma-aminobutyric acid level in cortical tubers in epileptic infants with tuberous sclerosis complex measured with the MEGA-editing J-difference method and a three-Tesla clinical MRI Instrument, Neuroimage, 47, 1207, 10.1016/j.neuroimage.2009.05.060 Theodore, 2007, Reduced hippocampal 5HT1A PET receptor binding and depression in temporal lobe epilepsy, Epilepsia, 48, 1526, 10.1111/j.1528-1167.2007.01089.x Theysohn, 2009, The human hippocampus at 7T – in vivo MRI, Hippocampus, 19, 1, 10.1002/hipo.20487 Thivard, 2006, Interictal diffusion MRI in partial epilepsies explored with intracerebral electrodes, Brain, 129, 375, 10.1093/brain/awh709 Thivard, 2005, Productive and perceptive language reorganization in temporal lobe epilepsy, Neuroimage, 24, 841, 10.1016/j.neuroimage.2004.10.001 Tyvaert, 2009, Noninvasive dynamic imaging of seizures in epileptic patients, Hum Brain Mapp, 30, 3993, 10.1002/hbm.20824 van der Lijn, 2008, Hippocampus segmentation in MR images using atlas registration, voxel classification, and graph cuts, Neuroimage, 43, 708, 10.1016/j.neuroimage.2008.07.058 Van Paesschen, 2003, SPECT perfusion changes during complex partial seizures in patients with hippocampal sclerosis, Brain, 126, 1103, 10.1093/brain/awg108 Vannest, 2008, Medial temporal fMRI activation reflects memory lateralization and memory performance in patients with epilepsy, Epilepsy Behav, 12, 410, 10.1016/j.yebeh.2007.11.012 Varghese, 2009, Clinical use of ictal SPECT in secondarily generalized tonic–clonic seizures, Brain, 132, 2102, 10.1093/brain/awp027 Vermathen, 2002, Temporal lobectomy for epilepsy: recovery of the contralateral hippocampus measured by (1)H MRS, Neurology, 59, 633, 10.1212/WNL.59.4.633 Vinton, 2007, The extent of resection of FDG-PET hypometabolism relates to outcome of temporal lobectomy, Brain, 130, 548, 10.1093/brain/awl232 Voets, 2009, Functional and structural changes in the memory network associated with left temporal lobe epilepsy, Hum Brain Mapp, 30, 4070, 10.1002/hbm.20830 Wagner, 2007, Hippocampal functional connectivity reflects verbal episodic memory network integrity, Neuroreport, 18, 1719, 10.1097/WNR.0b013e3282f0d3c5 Wagner, 2008, Differential effect of side of temporal lobe epilepsy on lateralization of hippocampal, temporolateral, and inferior frontal activation patterns during a verbal episodic memory task, Epilepsy Behav, 12, 382, 10.1016/j.yebeh.2007.11.003 Waites, 2006, Functional connectivity networks are disrupted in left temporal lobe epilepsy, Ann Neurol, 59, 335, 10.1002/ana.20733 Waites, 2005, How reliable are fMRI-EEG studies of epilepsy? A nonparametric approach to analysis validation and optimization, Neuroimage, 24, 192, 10.1016/j.neuroimage.2004.09.005 Wakamoto, 2008, Alpha-methyl-l-tryptophan positron emission tomography in epilepsy with cortical developmental malformations, Pediatr Neurol, 39, 181, 10.1016/j.pediatrneurol.2008.05.014 Walker, 2009, Gray matter volumes and cognitive ability in the epileptogenic brain malformation of periventricular nodular heterotopia, Epilepsy Behav, 15, 456, 10.1016/j.yebeh.2009.05.009 Wang, 2009, Function lateralization via measuring coherence laterality, Neuroimage, 47, 281, 10.1016/j.neuroimage.2009.03.069 Weber, 2006, Left hippocampal pathology is associated with atypical language lateralization in patients with focal epilepsy, Brain, 129, 346, 10.1093/brain/awh694 Weber, 2006, Presurgical language fMRI in patients with drug-resistant epilepsy: effects of task performance, Epilepsia, 47, 880, 10.1111/j.1528-1167.2006.00515.x Weitemeyer, 2005, The prognostic value of [F]FDG-PET in nonrefractory partial epilepsy, Epilepsia, 46, 1654, 10.1111/j.1528-1167.2005.00258.x Werhahn, 2006, Decreased dopamine D2/D3-receptor binding in temporal lobe epilepsy: an [18F]fallypride PET study, Epilepsia, 47, 1392, 10.1111/j.1528-1167.2006.00561.x Whiting, 2006, A systematic review of the effectiveness and cost-effectiveness of neuroimaging assessments used to visualise the seizure focus in people with refractory epilepsy being considered for surgery, Health Technol Assess, 10, 1, 10.3310/hta10040 Widjaja, 2007, Evaluation of subcortical white matter and deep white matter tracts in malformations of cortical development, Epilepsia, 48, 1460, 10.1111/j.1528-1167.2007.01105.x Wieshmann, 1997, Development of hippocampal atrophy: a serial magnetic resonance imaging study in a patient who developed epilepsy after generalized status epilepticus, Epilepsia, 38, 1238, 10.1111/j.1528-1157.1997.tb01222.x Willmann, 2006, The role of 1H magnetic resonance spectroscopy in pre-operative evaluation for epilepsy surgery. A meta-analysis, Epilepsy Res, 71, 149, 10.1016/j.eplepsyres.2006.06.004 Willmann, 2007, The contribution of 18F-FDG PET in preoperative epilepsy surgery evaluation for patients with temporal lobe epilepsy: a meta-analysis, Seizure, 16, 509, 10.1016/j.seizure.2007.04.001 Woermann, 1999, Abnormal cerebral structure in juvenile myoclonic epilepsy demonstrated with voxel-based analysis of MRI, Brain, 122, 2101, 10.1093/brain/122.11.2101 Woermann, 2003, Language lateralization by Wada test and fMRI in 100 patients with epilepsy, Neurology, 61, 699, 10.1212/01.WNL.0000078815.03224.57 Wolters, 2006, Influence of tissue conductivity anisotropy on EEG/MEG field and return current computation in a realistic head model: a simulation and visualization study using high-resolution finite element modeling, Neuroimage, 30, 813, 10.1016/j.neuroimage.2005.10.014 Yassa, 2009, A quantitative evaluation of cross-participant registration techniques for MRI studies of the medial temporal lobe, Neuroimage, 44, 319, 10.1016/j.neuroimage.2008.09.016 Yogarajah, 2008, Tractography of the parahippocampal gyrus and material specific memory impairment in unilateral temporal lobe epilepsy, Neuroimage, 40, 1755, 10.1016/j.neuroimage.2007.12.046 Yuan, 2006, FMRI shows atypical language lateralization in pediatric epilepsy patients, Epilepsia, 47, 593, 10.1111/j.1528-1167.2006.00474.x Yushkevich, 2009, A high-resolution computational atlas of the human hippocampus from postmortem magnetic resonance imaging at 9.4T, Neuroimage, 44, 385, 10.1016/j.neuroimage.2008.08.042