Current situation of H9N2 subtype avian influenza in China

Springer Science and Business Media LLC - Tập 48 - Trang 1-10 - 2017
Min Gu1,2,3, Lijun Xu1,2,4, Xiaoquan Wang1,2,3, Xiufan Liu1,2,3
1College of Veterinary Medicine, Yangzhou University, Yangzhou, China
2Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, China
3Jiangsu Key Laboratory of Zoonosis, Yangzhou University, Yangzhou, China
4Yangzhou Entry-Exit Inspection and Quarantine Bureau, Yangzhou, China

Tóm tắt

In China, H9N2 subtype avian influenza outbreak is firstly reported in Guangdong province in 1992. Subsequently, the disease spreads into vast majority regions nationwide and has currently become endemic there. Over vicennial genetic evolution, the viral pathogenicity and transmissibility have showed an increasing trend as year goes by, posing serious threat to poultry industry. In addition, H9N2 has demonstrated significance to public health as it could not only directly infect mankind, but also donate partial or even whole cassette of internal genes to generate novel human-lethal reassortants like H5N1, H7N9, H10N8 and H5N6 viruses. In this review, we mainly focused on the epidemiological dynamics, biological characteristics, molecular phylogeny and vaccine strategy of H9N2 subtype avian influenza virus in China to present an overview of the situation of H9N2 in China.

Tài liệu tham khảo

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