Nội dung được dịch bởi AI, chỉ mang tính chất tham khảo
Các tùy chọn điều trị liên ngành dựa trên bằng chứng hiện tại cho đau cơ xương ở trẻ em
Tóm tắt
Chúng tôi đánh giá sự phổ biến của đau cơ xương mạn tính ở trẻ em, nhu cầu lâm sàng, bằng chứng cho các phương pháp điều trị đau bằng dược lý, tâm lý, vật lý và các phương pháp bổ sung, cũng như sự phát triển tiềm năng trong tương lai của chăm sóc liên ngành và từ xa. Chúng tôi tóm tắt các Đánh giá Hệ thống Cochrane về các can thiệp dược lý, cho thấy sự thiếu hụt bằng chứng để ủng hộ hoặc phản bác việc sử dụng tất cả các loại thuốc trong quản lý đau. Các thử nghiệm cho NSAIDs không cho thấy sự ưu việt so với các đối chứng, cũng như các thử nghiệm cho thuốc chống trầm cảm, và không có thử nghiệm cho paracetamol hay thuốc opioid. Có những nghiên cứu về can thiệp tâm lý cho thấy triển vọng và sự hỗ trợ ngày càng gia tăng cho liệu pháp vật lý. Cách tiếp cận tối ưu vẫn là một chương trình điều trị liên ngành quy mô lớn, mặc dù dịch vụ này không có sẵn cho hầu hết mọi người. 1. Khi không có bằng chứng, một chương trình thử nghiệm hiện đang được yêu cầu cấp bách để thiết lập cơ sở bằng chứng cho các thuốc giảm đau được kê đơn rộng rãi cho trẻ em và thanh thiếu niên mắc đau cơ xương mạn tính. 2. Cho đến khi bằng chứng đó có sẵn, việc xem xét thuốc là một nhiệm vụ thiết yếu trong dân số này. 3. Chúng tôi cần nhiều ví dụ và đánh giá hiệu quả của các can thiệp liên ngành quy mô lớn cho quản lý đau mạn tính, được mô tả chi tiết để các nhà nghiên cứu và bác sĩ lâm sàng có thể phân tích các thành phần điều trị tích cực có thể. 4. Các phương pháp điều trị trực tuyến có khả năng sẽ rất quan trọng trong tương lai. Chúng tôi cần xác định những khía cạnh nào của điều trị cho trẻ em và thanh niên có thể được cung cấp hiệu quả theo cách này, điều này sẽ giúp giảm gánh nặng cho số lượng lớn bệnh nhân cần hỗ trợ từ một số ít chuyên gia.
Từ khóa
#đau cơ xương mạn tính #trẻ em #điều trị dược lý #liệu pháp tâm lý #liệu pháp vật lý #chăm sóc liên ngànhTài liệu tham khảo
King S, Chambers CT, Huguet A, MacNevin RC, McGrath PH, Parker L, et al. The epidemiology of chronic pain in children and adolescents revisited: a systematic review. Pain. 2011;152(12):2729–38.
Rhee H, Miles MS, Halpern CT, Holditch-Davis D. Prevalence of recurrent physical symptoms in US adolescents. Pediatr Nurs. 2005;31:314–50.
Tan A, Strauss VY, Prothero J, Dunn KM. Epidemiology of paediatric presentations with musculoskeletal problems in primary care. BMC Musculoskelet Disord. 2018;19(1):40–5.
Clinch J. Chronic musculoskeletal pain in children and adolescents. In Watts RA, Conaghan PG, Denton C, Foster H, Isaacs J, Müller-Ladner U (Eds). Oxford Textbook of Rheumatology (4ed.). Oxford University Press; 2013.
Anthony KK, Schanberg LE. Assessment and management of pain syndromes and arthritis pain in children and adolescents. Rheum Dis Clin. 2007;33(3):625–60.
Connelly M, Kelly AK, Bromberg MH, Franks L, Gil KM, Schanberg LE. Emotion regulation predicts pain and functioning in children with juvenile idiopathic arthritis. Pediat Rheumat. 2012;10:A32.
Vuorimaa H, Tamm K, Honkanen V, Komulainen E, Konttinen YT, Santavirta N. Parents and children as agents of disease management in JIA. Child Care Health Dev. 2009;35(4):578–85.
Haverman L, Grootenhuis MA, van den Berg JM, van Veenendaal M, Dolman KM, Swart HF, et al. Predictors of health-related quality of life in children and adolescents with juvenile idiopathic arthritis: results from a web-based survey. Arthrit Care Res. 2012;64(5):694–703.
Adam V, St-Pierre Y, Fautrel B, Clarke AE, Duffy CM, Penrod JR. What is the impact of adolescent arthritis and rheumatism? Evidence from a national sample of Canadians. J Rheumatol. 2005;32(2):354–61.
Harrison L, Wilson S, Munafò MR. Exploring the associations between sleep problems and chronic musculoskeletal pain in adolescents: a prospective cohort study. Pain Res Manag. 2014;19(5):e139–45.
Groenewald CB, Essner BS, Wright D, Fesinmeyer MD, Palermo TM. The economic costs of chronic pain among a cohort of treatment-seeking adolescents in the United States. J Pain. 2014;15(9):925–33.
Guite JW, McCue RL, Sherker JL, Sherry DD, Rose JB. Relationships among pain, protective parental responses, and disability for adolescents with chronic musculoskeletal pain: the mediating role of pain catastrophizing. Clin J Pain. 2011;27(9):775–81.
El-Metwally A, Salminen JJ, Auvinen A, Kautiainen H, Mikkelsson M. Prognosis of non-specific musculoskeletal pain in preadolescents: a prospective 4-year follow-up study till adolescence. Pain. 2004;110(3):550–9.
Leino-Arjas P, Rajaleid K, Mekuria G, Nummi T, Virtanen P, Hammarström A. Trajectories of musculoskeletal pain from adolescence to middle age. Pain. 2018;159(1):67–74. Longitudinal study evaluating the what contributes to continued musculoskeletal pain across the lifespan.
Clinch J, Eccleston C. Chronic musculoskeletal pain in children: assessment and management. Rheumatology. 2009;48(5):466–74.
Stinson J, Connelly M, Kamper SJ, Herlin T, April KT. Models of care for addressing chronic musculoskeletal pain and health in children and adolescents. Best Pract Res Clin Rheumatol. 2016;30(3):468–82. Review of models of care for pediatric chronic musculoskeletal pain.
Eccleston C, Cooper TE, Fisher E, Anderson B, Wilkinson N. Non-steroidal anti-inflammatory drugs (NSAIDs) for chronic non-cancer pain in children and adolescents. Cochrane Database of Systematic Reviews. 2017;2 Systematic review of evidence for effectiveness of NSAIDS for pediatric chronic pain.
Cooper TE, Fisher E, Anderson B, Wilkinson N, Williams G, Eccleston C. Paracetamol (acetaminophen) for chronic non-cancer pain in children and adolescents. Cochrane Database of Systematic Reviews. 2017;2 Systematic review of evidence for effectiveness of paracetamol for pediatric chronic pain.
Cooper TE, Fisher E, Wiffen PJ. Opioids for chronic non-cancer pain in children and adolescents. Cochrane Database Syst Rev. 2017;2 Systematic review of evidence for effectiveness of opioids for pediatric chronic pain.
Cooper TE, Heathcote LC, Clinch J, Gold JI, Howard R, Lord SM, Schecher N, Wood C, Wiffen PJ. Antidepressants for chronic non-cancer pain in children and adolescents. Cochrane Database Syst Rev 2017. https://doi.org/10.1002/14651858.CD012535.pub2.
Eccleston C. Malleson P. Managing chronic pain in children and adolescents: we need to address the embarrassing lack of data for this common problem BMJ 2003;326(7404):1408-1409.
Coakley R, Wihak T. Evidence-based psychological interventions for the management of pediatric chronic pain: new directions in research and clinical practice. Children. 2017;4(2):9.
Palermo TM. Cognitive-behavioural therapy for chronic pain in children and adolescents. New York: Oxford University Press; 2012.
Eccleston C, Palermo TM, Williams ACC, Lewandowski Holley A, Morley S, Fisher E, et al. Psychological therapies for the management of chronic and recurrent pain in children and adolescents. Cochrane Database Syst Rev. 2014;5 https://doi.org/10.1002/14651858.CD003968.pub4. Systematic review of psychological therapy for pediatric chronic pain.
Fisher E, Heathcote L, Palermo TM, Williams ACC, Lau J, Eccleston C. Systematic review and meta-analysis of psychological therapies for children with chronic pain. J Pediatr Psychol. 2014;39(8):763–82.
Palermo TM, Law EF, Fales J, Bromberg MH, Jessen-Fiddick T, Tai G. Internet-delivered cognitive-behavioral treatment for adolescents with chronic pain and their parents: a randomized controlled multicenter trial. Pain. 2016;57(1):174.
Palermo TM, Wilson ACC, Peters M, Lewandowski A, Somhegyi H. Randomized controlled trial of an Internet-delivered family cognitive–behavioral therapy intervention for children and adolescents with chronic pain. Pain. 2009;146(1):205–13.
Wicksell RK, Melin L, Lekander M, Olsson GL. Evaluating the effectiveness of exposure and acceptance strategies to improve functioning and quality of life in longstanding pediatric pain—a randomized controlled trial. Pain. 2009;141(3):248–57.
Fisher E, Law E, Palermo TM, Eccleston C. Psychological therapies (remotely delivered) for the management of chronic and recurrent pain in children and adolescents. Cochrane Database Syst Rev 2015. https://doi.org/10.1002/14651858.CD011118.
Stinson JN, McGrath PJ, Hodnett ED, Feldman BM, Duffy CM, Huber AM, et al. An internet-based self-management program with telephone support for adolescents with arthritis: a pilot randomized controlled trial. J Rheumatol. 2010;37(9):1944–52.
Kashikar-Zuck S, Swain NF, Jones BA, Graham TB. Efficacy of cognitive-behavioral intervention for juvenile primary fibromyalgia syndrome. J Rheumatol. 2005;32(8):1594–602.
Kashikar-Zuck S, Ting TV, Lynch-Jordan AM. Cognitive behavioral therapy for the treatment of juvenile fibromyalgia: a multisite, single-blind, randomized, controlled clinical trial. Arthritis & Rheumatol. 2012;64(1):297–305.
Levy RL, Langer SL, et al. Cognitive-behavioral therapy for children with functional abdominal pain and their parents decreases pain and other symptoms. Am J Gastroenterol. 2010;105(4):946–56.
Trautmann E, Kröner-Herwig B. A randomized controlled trial of Internet-based self-help training for recurrent headache in childhood and adolescence. Behav Res Ther. 2010;48(1):28–37.
Forgeron PA, King S, Stinson JN, McGrath PJ, MacDonald AJ, Chambers CT. Social functioning and peer relationships in children and adolescents with chronic pain: a systematic review. Pain Res Manag. 2010;5(1):27–41.
Logan DE, Simons LE, Stein MJ, Chastain L. School impairment in adolescents with chronic pain. J Pain. 2008;9(5):407–16.
Stinson J, Kohut SA, Spiegel L. The iPeer2Peer program: a pilot randomized controlled trial in adolescents with juvenile idiopathic arthritis. Pediat Rheumatol. 2016;14(1):48. Evaluation of an innovative program for providing peer support to youth with arthritis.
Cunningham NR, Kashikar-Zuck S. Nonpharmacologic treatment of pain in rheumatic diseases and other musculoskeletal pain conditions. Curr Rheumatol Rep. 2013;15(2):306–19.
Stephens S, Feldman BM, Bradley N, Schneiderman J, Wright V, Singh-Grewal D, et al. Feasibility and effectiveness of an aerobic exercise program in children with fibromyalgia: results of a randomized controlled pilot trial. Arthrit Care & Res. 2008;59(10):1399–406.
Takken T, Van Brussel M, Engelbert RH, van der Net JJ, Kuis W, Helders PP. Exercise therapy in juvenile idiopathic arthritis. Cochrane Libr. 2008;
Gill JR, Brown CA. A structured review of the evidence for pacing as a chronic pain intervention. Eur J Pain. 2009;13:214–6.
Nielson WR, Jensen MP, Karsdorp PA, Vlaeyen JW. Activity pacing in chronic pain: concepts, evidence, and future directions. Clin J Pain. 2013;29:461–8.
Andrews N, Deen M. Defining activity pacing: is it time to jump off the merry-go-round? J Pain. 2016;17(12):1359–62.
Hadzic R, Sharpe L, Wood BM. The relationship between pacing and avoidance in chronic pain: a systematic review and meta-analysis. J Pain. 2017;18:1165–73.
Smith SM, Sumar B, Dixon KA. Musculoskeletal pain in overweight and obese children. Int J obesity. 2014;38(1):11–5.
Young L, Kemper KJ. Integrative care for pediatric patients with pain. J Alternative and Complem Med. 2013;19(7):627–32.
Straube S, Derry S, Straube C, Moore RA. Vitamin D for the treatment of chronic painful conditions in adults. Cochrane Libr 2015.
Meltzer LJ, Mindell JA. Systematic review and meta-analysis of behavioral interventions for pediatric insomnia. J Pediatr Psychol. 2014;39(8):932–48.
Steultjens EE. Dekker JJ, Bouter LM, Schaardenburg DD, Kuyk MAM, Van den Ende, E C. Occupational therapy for rheumatoid arthritis. Cochrane Libr 2004.
Lin YC, Lee AC, Kemper KJ, Berde CB. Use of complementary and alternative medicine in pediatric pain management service: a survey. Pain Med. 2005;6(6):452–8.
Hagen LE Schneider R, Stephens D, Modrusan D, Feldman BM. Use of complementary and alternative medicine by pediatric rheumatology patients. Arthritis Rheumatol. 2003;49:3–6.
Tsao JC, Zeltzer LK. Complementary and alternative medicine approaches for pediatric pain: a review of the state-of-the-science. Evid Based Complement Alternat Med. 2005;2(2):149–59.
Golianu B, Yeh AM, Brooks M. Acupuncture for pediatric pain. Children. 2014;1(2):134–48.
Suresh S, Wang S, Porfyris S, Kamisinki-Sol R, Steinhorn DM. Massage therapy in outpatient pediatric chronic pain patients: do they facilitate significant reductions in levels of distress, pain, tension, discomfort, and mood alterations? Pediatr Anes. 2008;18(9):884–7.
Evans S, Moieni M, Taub R, Subramanian SK, Tsao JC, Sternlieb B, et al. Iyengar yoga for young adults with rheumatoid arthritis: results from a mixed-methods pilot study. K Pain Symp Manag. 2010;39(5):904–13.
Hechler T, Kanstrup M, Holley AL, Simons LE, Wicksell R, Hirschfeld G, et al. Systematic review on intensive interdisciplinary pain treatment of children with chronic pain. Pediatrics. 2015;136(1):115–27.
Mahrer NE, Gold JI, Luu M, Herman PM. A cost-analysis of an interdisciplinary pediatric chronic pain clinic. J Pain. 2018;19(2):158–65. Cost-analysis of interdisciplinary treatment for pediatric chronic pain.
Fisher E, Law, E, Palermo TM, Eccleston C. Psychological therapies (remotely delivered) for the management of chronic and recurrent pain in children and adolescents. Cochrane Database of Systematic Reviews 2014. Systematic review of remotely delivered psychological therapy for pediatric chronic pain.
Vervoort T, Logan DE, Goubert L, De Clercq B, Hublet A. Severity of pediatric pain in relation to school-related functioning and teacher support: an epidemiological study among school-aged children and adolescents. Pain. 2014;155(6):1118–27.
Logan DE, Coakley RM, Scharff L. Teachers’ perceptions of and responses to adolescents with chronic pain syndromes. J Pediatr Psychol. 2007;32(2):139–49.